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The map label for this gene is secY

Identifier: 145294720

GI number: 145294720

Start: 726828

End: 728150

Strand: Direct

Name: secY

Synonym: cgR_0668

Alternate gene names: 145294720

Gene position: 726828-728150 (Clockwise)

Preceding gene: 145294709

Following gene: 145294722

Centisome position: 21.93

GC content: 51.55

Gene sequence:

>1323_bases
GTGTCCGCCATTATTCAGGCATTCAAGGACGCCGATCTGCGTAAGAAGATTTTCTTCACTATCGCAATGATCGTTCTATA
CCGCATCGGTGCGCAGATCCCTTCCCCGGGAGTTGACTATGCAACGATTAGTGGTCGTCTGCGTGACTTGACTCAGGATC
AGTCAAGCGTTTATTCGCTGATTAACCTGTTTTCCGGTGGAGCGCTGCTGCAGCTGTCCATTTTTGCTATTGGTATCATG
CCGTACATCACGGCGTCTATTATCGTGCAGCTGCTGACTGTGGTTATTCCACACTTTGAGGAGTTGAAGAAGGAAGGCCA
GTCTGGCCAGGCCAAGATGATGCAGTACACCAGGTACTTAACGGTTGCCTTGGCGTTGCTTCAGTCTTCGGGCATCGTCG
CGTTGGCGGACCGTGAGCAGCTGCTTGGCGCAGGCATTCGCGTGCTGTCGGCTGATCGCAACTTCTTCGACCTCATTGTT
TTGGTCATCACCATGACTGCGGGTGCAGTGCTTGTGATGTGGATGGGTGAGCTCATCACGGAAAAGGGCGTAGGCAATGG
TATGTCGCTGCTGATTTTCGCTGGTATCGCAACTCGCCTCCCAACTGATGGCATGAACATTCTGGGCAACTCCGGCGGCG
TGGTTTTCGCTGTTGTTCTGGCTTCCGTTCTGATCCTGGTCATTGGTGTTGTATTCGTTGAGCAGGGCCAGCGTCGTATT
CCAGTGCAGTACGCAAAGCGCATGGTGGGTCGTCGTCAGTACGGTGGTTCTTCCACTTACCTGCCTTTGAAGGTCAACCA
AGCTGGTGTTATCCCAGTGATCTTCGCGTCTTCCTTGATTTACATGCCAGTGCTGATTACTCAGATCGTGAACTCTGGTT
CGCTGGAAGTGTCTGATAACTGGTGGCAGCGCAACATCATTGCGCACCTGCAGACGCCTTCTTCCTGGCAGTACATTGTT
TTGTACTTTGCACTGACCATCTTCTTCTCTTACTTCTATGTTTCTGTTCAGTATGATCCAGCTGAGCAGGCTGAAAACAT
GAAGAAGTACGGCGGATTTATCCCTGGTATTCGTCCGGGCCGTCCGACTGCTGAGTACTTGGGATTCGTCATGAACCGCC
TGCTGTTTGTTGGTTCCCTGTACCTGGCTGTCATTGCTGTGCTGCCAAACATTATGCTGGATCTAGGTGTTGACGCCGGT
TCGGCCGGAGCAACTCCATTCGGCGGAACCGCAATCTTGATTCTTGTATCTGTTGCACTGACCACAGTGAAGCAGATTGA
GAGCCAGCTCCTGCAAAGCAACTACGAAGGACTTCTAAAATAA

Upstream 100 bases:

>100_bases
TGTAATCGGACCAGGATCTAAAGAACACATCTCCCGGTACCTTTTAGTCACTATTGTGAAAATATGTGGGTTTGAAGTGC
TGAGGAGGCCAGGAGGATAA

Downstream 100 bases:

>100_bases
TGCGACTCGTACTCCTCGGACCTCCCGGTGCTGGTAAGGGCACCCAGGCTGCAATTCTCTCTGAGAAGCTTGGCATTCCT
CACATTTCTACTGGCGATCT

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSAIIQAFKDADLRKKIFFTIAMIVLYRIGAQIPSPGVDYATISGRLRDLTQDQSSVYSLINLFSGGALLQLSIFAIGIM
PYITASIIVQLLTVVIPHFEELKKEGQSGQAKMMQYTRYLTVALALLQSSGIVALADREQLLGAGIRVLSADRNFFDLIV
LVITMTAGAVLVMWMGELITEKGVGNGMSLLIFAGIATRLPTDGMNILGNSGGVVFAVVLASVLILVIGVVFVEQGQRRI
PVQYAKRMVGRRQYGGSSTYLPLKVNQAGVIPVIFASSLIYMPVLITQIVNSGSLEVSDNWWQRNIIAHLQTPSSWQYIV
LYFALTIFFSYFYVSVQYDPAEQAENMKKYGGFIPGIRPGRPTAEYLGFVMNRLLFVGSLYLAVIAVLPNIMLDLGVDAG
SAGATPFGGTAILILVSVALTTVKQIESQLLQSNYEGLLK

Sequences:

>Translated_440_residues
MSAIIQAFKDADLRKKIFFTIAMIVLYRIGAQIPSPGVDYATISGRLRDLTQDQSSVYSLINLFSGGALLQLSIFAIGIM
PYITASIIVQLLTVVIPHFEELKKEGQSGQAKMMQYTRYLTVALALLQSSGIVALADREQLLGAGIRVLSADRNFFDLIV
LVITMTAGAVLVMWMGELITEKGVGNGMSLLIFAGIATRLPTDGMNILGNSGGVVFAVVLASVLILVIGVVFVEQGQRRI
PVQYAKRMVGRRQYGGSSTYLPLKVNQAGVIPVIFASSLIYMPVLITQIVNSGSLEVSDNWWQRNIIAHLQTPSSWQYIV
LYFALTIFFSYFYVSVQYDPAEQAENMKKYGGFIPGIRPGRPTAEYLGFVMNRLLFVGSLYLAVIAVLPNIMLDLGVDAG
SAGATPFGGTAILILVSVALTTVKQIESQLLQSNYEGLLK
>Mature_439_residues
SAIIQAFKDADLRKKIFFTIAMIVLYRIGAQIPSPGVDYATISGRLRDLTQDQSSVYSLINLFSGGALLQLSIFAIGIMP
YITASIIVQLLTVVIPHFEELKKEGQSGQAKMMQYTRYLTVALALLQSSGIVALADREQLLGAGIRVLSADRNFFDLIVL
VITMTAGAVLVMWMGELITEKGVGNGMSLLIFAGIATRLPTDGMNILGNSGGVVFAVVLASVLILVIGVVFVEQGQRRIP
VQYAKRMVGRRQYGGSSTYLPLKVNQAGVIPVIFASSLIYMPVLITQIVNSGSLEVSDNWWQRNIIAHLQTPSSWQYIVL
YFALTIFFSYFYVSVQYDPAEQAENMKKYGGFIPGIRPGRPTAEYLGFVMNRLLFVGSLYLAVIAVLPNIMLDLGVDAGS
AGATPFGGTAILILVSVALTTVKQIESQLLQSNYEGLLK

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family

Homologues:

Organism=Escherichia coli, GI1789696, Length=438, Percent_Identity=43.6073059360731, Blast_Score=301, Evalue=4e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECY_CORGL (P38376)

Other databases:

- EMBL:   D14162
- EMBL:   AF331925
- EMBL:   BA000036
- EMBL:   BX927149
- PIR:   I40340
- RefSeq:   NP_599793.1
- RefSeq:   YP_224848.1
- ProteinModelPortal:   P38376
- GeneID:   1018561
- GeneID:   3342606
- GenomeReviews:   BA000036_GR
- GenomeReviews:   BX927147_GR
- KEGG:   cgb:cg0647
- KEGG:   cgl:NCgl0532
- HOGENOM:   HBG565931
- OMA:   FAQSIMF
- PhylomeDB:   P38376
- ProtClustDB:   PRK09204
- BioCyc:   CGLU196627:CG0647-MONOMER
- InterPro:   IPR002208
- InterPro:   IPR023201
- PANTHER:   PTHR10906
- PIRSF:   PIRSF004557
- PRINTS:   PR00303
- TIGRFAMs:   TIGR00967

Pfam domain/function: PF00344 SecY; SSF103491 SecY

EC number: NA

Molecular weight: Translated: 47904; Mature: 47773

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00755 SECY_1; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb42cfc8)-; HASH(0x40815e48)-; HASH(0x1a775d04)-; HASH(0x1bd9a894)-; HASH(0x1b638170)-; HASH(0x1bb96b04)-; HASH(0x1baff3b4)-; HASH(0x1ab70404)-; HASH(0x1b89db5c)-; HASH(0x1a98f8fc)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIIQAFKDADLRKKIFFTIAMIVLYRIGAQIPSPGVDYATISGRLRDLTQDQSSVYSL
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
INLFSGGALLQLSIFAIGIMPYITASIIVQLLTVVIPHFEELKKEGQSGQAKMMQYTRYL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
TVALALLQSSGIVALADREQLLGAGIRVLSADRNFFDLIVLVITMTAGAVLVMWMGELIT
HHHHHHHHCCCEEEECCHHHHHHCCHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EKGVGNGMSLLIFAGIATRLPTDGMNILGNSGGVVFAVVLASVLILVIGVVFVEQGQRRI
HCCCCCCHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
PVQYAKRMVGRRQYGGSSTYLPLKVNQAGVIPVIFASSLIYMPVLITQIVNSGSLEVSDN
CHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
WWQRNIIAHLQTPSSWQYIVLYFALTIFFSYFYVSVQYDPAEQAENMKKYGGFIPGIRPG
HHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHHCCCCCCCCCC
RPTAEYLGFVMNRLLFVGSLYLAVIAVLPNIMLDLGVDAGSAGATPFGGTAILILVSVAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
TTVKQIESQLLQSNYEGLLK
HHHHHHHHHHHHCCHHHCCH
>Mature Secondary Structure 
SAIIQAFKDADLRKKIFFTIAMIVLYRIGAQIPSPGVDYATISGRLRDLTQDQSSVYSL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
INLFSGGALLQLSIFAIGIMPYITASIIVQLLTVVIPHFEELKKEGQSGQAKMMQYTRYL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
TVALALLQSSGIVALADREQLLGAGIRVLSADRNFFDLIVLVITMTAGAVLVMWMGELIT
HHHHHHHHCCCEEEECCHHHHHHCCHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EKGVGNGMSLLIFAGIATRLPTDGMNILGNSGGVVFAVVLASVLILVIGVVFVEQGQRRI
HCCCCCCHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
PVQYAKRMVGRRQYGGSSTYLPLKVNQAGVIPVIFASSLIYMPVLITQIVNSGSLEVSDN
CHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
WWQRNIIAHLQTPSSWQYIVLYFALTIFFSYFYVSVQYDPAEQAENMKKYGGFIPGIRPG
HHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHHCCCCCCCCCC
RPTAEYLGFVMNRLLFVGSLYLAVIAVLPNIMLDLGVDAGSAGATPFGGTAILILVSVAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
TTVKQIESQLLQSNYEGLLK
HHHHHHHHHHHHCCHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8112597; 12948626