| Definition | Corynebacterium glutamicum R chromosome, complete genome. |
|---|---|
| Accession | NC_009342 |
| Length | 3,314,179 |
Click here to switch to the map view.
The map label for this gene is morA [H]
Identifier: 145294210
GI number: 145294210
Start: 182480
End: 182938
Strand: Direct
Name: morA [H]
Synonym: cgR_0167
Alternate gene names: 145294210
Gene position: 182480-182938 (Clockwise)
Preceding gene: 145294209
Following gene: 145294211
Centisome position: 5.51
GC content: 64.05
Gene sequence:
>459_bases ATGGTCCCCCACCTCGACCGTCTCATGGACCGGGCCACGGTTGCCCCGGCGGTCAATCAGCTGGAGATCCACCCCTACTT CCAGCAGCGCGAGGTGCTCGCCCGCAACGCTGAGCTGGGAATTATCAGCCAGGCGTGGTCACCGATCGGGGGCATCACCT TCTACCGGGACAGCGGACATGGCAGCACCCTGGAGGATCCCACCATTGGTGAGATCGCGGCCGATCATGCCAAGACCCCG GCGCAGGTGATGCTGCGCTGGCACCTGCAGCAGGGTCGTCAGGTCATCCCGAAGTCGGTTACGCCCTCGCGTATCAGGGA GAACTTCGCGGTCTTCGATTTCGAGCTCTCATCGGATGAACTGGCCAGCATCGACGCCTTGGACACCGGTGTCCGCGGGG GTCCCGAGCCGGAGCAAGTCACCCTGGCGTCCTTCGGAATCGAGATCCCGGAAGCCTAA
Upstream 100 bases:
>100_bases GGCGCTGCCGGAGGACTTTGAAGCCACGATCGAGGCCTACCGGGCGTTGGAGAGACTGCAGGCCGACGGGCGGGTCCGAG CGATTGGGGTTAGCAATTTC
Downstream 100 bases:
>100_bases CGAGTACAAACACCGCCAGTATCTGAACCTCAACAGGGAACCCGGCCATACCTTTAAGGTGCGGCCGTGTTCCTTGTTTC TGTGGCGGGTAGGAAACGGG
Product: hypothetical protein
Products: NA
Alternate protein names: Naloxone reductase [H]
Number of amino acids: Translated: 152; Mature: 152
Protein sequence:
>152_residues MVPHLDRLMDRATVAPAVNQLEIHPYFQQREVLARNAELGIISQAWSPIGGITFYRDSGHGSTLEDPTIGEIAADHAKTP AQVMLRWHLQQGRQVIPKSVTPSRIRENFAVFDFELSSDELASIDALDTGVRGGPEPEQVTLASFGIEIPEA
Sequences:
>Translated_152_residues MVPHLDRLMDRATVAPAVNQLEIHPYFQQREVLARNAELGIISQAWSPIGGITFYRDSGHGSTLEDPTIGEIAADHAKTP AQVMLRWHLQQGRQVIPKSVTPSRIRENFAVFDFELSSDELASIDALDTGVRGGPEPEQVTLASFGIEIPEA >Mature_152_residues MVPHLDRLMDRATVAPAVNQLEIHPYFQQREVLARNAELGIISQAWSPIGGITFYRDSGHGSTLEDPTIGEIAADHAKTP AQVMLRWHLQQGRQVIPKSVTPSRIRENFAVFDFELSSDELASIDALDTGVRGGPEPEQVTLASFGIEIPEA
Specific function: Oxidizes only the C-6 hydroxy group of morphine and codeine [H]
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldo/keto reductase family [H]
Homologues:
Organism=Homo sapiens, GI223468663, Length=133, Percent_Identity=42.1052631578947, Blast_Score=105, Evalue=1e-23, Organism=Homo sapiens, GI24497577, Length=130, Percent_Identity=39.2307692307692, Blast_Score=104, Evalue=2e-23, Organism=Homo sapiens, GI5174391, Length=130, Percent_Identity=39.2307692307692, Blast_Score=104, Evalue=2e-23, Organism=Homo sapiens, GI4502049, Length=118, Percent_Identity=46.6101694915254, Blast_Score=104, Evalue=3e-23, Organism=Homo sapiens, GI291291012, Length=132, Percent_Identity=41.6666666666667, Blast_Score=103, Evalue=4e-23, Organism=Homo sapiens, GI310109924, Length=119, Percent_Identity=40.3361344537815, Blast_Score=96, Evalue=1e-20, Organism=Homo sapiens, GI310109922, Length=119, Percent_Identity=40.3361344537815, Blast_Score=96, Evalue=1e-20, Organism=Homo sapiens, GI5453543, Length=119, Percent_Identity=40.3361344537815, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI310109920, Length=119, Percent_Identity=40.3361344537815, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI45446745, Length=119, Percent_Identity=40.3361344537815, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI4503285, Length=119, Percent_Identity=40.3361344537815, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI93277124, Length=131, Percent_Identity=36.6412213740458, Blast_Score=95, Evalue=3e-20, Organism=Homo sapiens, GI5174695, Length=119, Percent_Identity=37.8151260504202, Blast_Score=90, Evalue=6e-19, Organism=Homo sapiens, GI24497583, Length=118, Percent_Identity=37.2881355932203, Blast_Score=89, Evalue=2e-18, Organism=Homo sapiens, GI24497585, Length=119, Percent_Identity=36.9747899159664, Blast_Score=86, Evalue=1e-17, Organism=Homo sapiens, GI300116271, Length=118, Percent_Identity=36.4406779661017, Blast_Score=84, Evalue=3e-17, Organism=Homo sapiens, GI300116273, Length=98, Percent_Identity=36.734693877551, Blast_Score=68, Evalue=3e-12, Organism=Escherichia coli, GI87082198, Length=138, Percent_Identity=47.1014492753623, Blast_Score=132, Evalue=7e-33, Organism=Escherichia coli, GI1786400, Length=130, Percent_Identity=35.3846153846154, Blast_Score=78, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17537077, Length=130, Percent_Identity=43.8461538461538, Blast_Score=119, Evalue=8e-28, Organism=Caenorhabditis elegans, GI17537075, Length=131, Percent_Identity=43.5114503816794, Blast_Score=115, Evalue=6e-27, Organism=Caenorhabditis elegans, GI71998625, Length=131, Percent_Identity=35.8778625954198, Blast_Score=105, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17564128, Length=151, Percent_Identity=35.7615894039735, Blast_Score=94, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17538386, Length=125, Percent_Identity=37.6, Blast_Score=91, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17561298, Length=127, Percent_Identity=38.5826771653543, Blast_Score=90, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17537079, Length=133, Percent_Identity=32.3308270676692, Blast_Score=77, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17550248, Length=117, Percent_Identity=32.4786324786325, Blast_Score=70, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17552492, Length=140, Percent_Identity=27.8571428571429, Blast_Score=67, Evalue=3e-12, Organism=Saccharomyces cerevisiae, GI6320576, Length=134, Percent_Identity=36.5671641791045, Blast_Score=82, Evalue=4e-17, Organism=Saccharomyces cerevisiae, GI6324694, Length=114, Percent_Identity=36.8421052631579, Blast_Score=80, Evalue=2e-16, Organism=Saccharomyces cerevisiae, GI6322556, Length=127, Percent_Identity=29.1338582677165, Blast_Score=77, Evalue=1e-15, Organism=Saccharomyces cerevisiae, GI6319625, Length=127, Percent_Identity=31.496062992126, Blast_Score=65, Evalue=4e-12, Organism=Drosophila melanogaster, GI24644950, Length=134, Percent_Identity=41.044776119403, Blast_Score=107, Evalue=2e-24, Organism=Drosophila melanogaster, GI221378297, Length=134, Percent_Identity=41.044776119403, Blast_Score=107, Evalue=2e-24, Organism=Drosophila melanogaster, GI24662789, Length=130, Percent_Identity=37.6923076923077, Blast_Score=88, Evalue=2e-18, Organism=Drosophila melanogaster, GI24657054, Length=134, Percent_Identity=35.0746268656716, Blast_Score=86, Evalue=1e-17, Organism=Drosophila melanogaster, GI20129731, Length=130, Percent_Identity=36.1538461538462, Blast_Score=83, Evalue=6e-17, Organism=Drosophila melanogaster, GI21356425, Length=148, Percent_Identity=31.0810810810811, Blast_Score=83, Evalue=8e-17, Organism=Drosophila melanogaster, GI24662785, Length=115, Percent_Identity=40.8695652173913, Blast_Score=79, Evalue=8e-16, Organism=Drosophila melanogaster, GI24662781, Length=115, Percent_Identity=40.8695652173913, Blast_Score=79, Evalue=9e-16, Organism=Drosophila melanogaster, GI24663317, Length=132, Percent_Identity=31.8181818181818, Blast_Score=75, Evalue=1e-14, Organism=Drosophila melanogaster, GI45553081, Length=135, Percent_Identity=31.1111111111111, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI281366140, Length=135, Percent_Identity=31.1111111111111, Blast_Score=68, Evalue=2e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR018170 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: =1.1.1.218 [H]
Molecular weight: Translated: 16727; Mature: 16727
Theoretical pI: Translated: 4.65; Mature: 4.65
Prosite motif: PS00063 ALDOKETO_REDUCTASE_3
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.0 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVPHLDRLMDRATVAPAVNQLEIHPYFQQREVLARNAELGIISQAWSPIGGITFYRDSGH CCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCEEHHHCCCCCCCEEEEEECCC GSTLEDPTIGEIAADHAKTPAQVMLRWHLQQGRQVIPKSVTPSRIRENFAVFDFELSSDE CCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCEECCCCCCHHHHHCCCEEEEEEECCCC LASIDALDTGVRGGPEPEQVTLASFGIEIPEA HHHHHHHHCCCCCCCCCCEEEHHHCCEECCCC >Mature Secondary Structure MVPHLDRLMDRATVAPAVNQLEIHPYFQQREVLARNAELGIISQAWSPIGGITFYRDSGH CCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCEEHHHCCCCCCCEEEEEECCC GSTLEDPTIGEIAADHAKTPAQVMLRWHLQQGRQVIPKSVTPSRIRENFAVFDFELSSDE CCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCEECCCCCCHHHHHCCCEEEEEEECCCC LASIDALDTGVRGGPEPEQVTLASFGIEIPEA HHHHHHHHCCCCCCCCCCEEEHHHCCEECCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8452544; 2012614; 8192670 [H]