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The map label for this gene is ung [H]

Identifier: 138896998

GI number: 138896998

Start: 3475160

End: 3475849

Strand: Reverse

Name: ung [H]

Synonym: GTNG_3369

Alternate gene names: 138896998

Gene position: 3475849-3475160 (Counterclockwise)

Preceding gene: 138897002

Following gene: 138896997

Centisome position: 97.9

GC content: 53.48

Gene sequence:

>690_bases
ATGCCGATTTTAAAAAACGATTGGGCTCCGCTTCTAGAAGAGGAGTTTCAAAAGCCATATTACTTAAAGCTGCGCGAGTT
TTTAAAAGAAGAGTACCGGACGCGAACGATTTATCCTGATATGTACGATATTTTCAACGCCCTTCATTATACGCCGTACG
CGAACGTCAAAGTCGTGTTGCTCGGGCAAGATCCGTACCACGGCCCAGGGCAGGCGCACGGGTTGAGTTTCTCCGTTAAG
CCGGGCGTTCCGGTGCCGCCGTCTTTGGTCAACATTTTTAAAGAACTGCATGATGACCTTGGCTGTTACATACCGGATAA
CGGCTACCTCGTGAAATGGGCAAAGCAAGGGGTGCTGTTGCTAAACACCGTGCTGACGGTTCGGCGCGGCCAGGCAAATT
CCCACCGCGGCAAAGGGTGGGAACATTTCACCGACCGCGTCATTGAGCTCGTCAACGAAAAAGACGATCCAGTCGTCTTT
TTGCTTTGGGGGCGGAACGCGCAAGAGAAAAAAGAACGCATCACGAACCCGCGTCATCATATCATCGAGGCGCCGCACCC
GAGCCCGTTTTCTGCCGCGCGCGGCTTTTTCGGTCACCGCCCGTTTTCGCGGACGAACGCATTTTTGACAAAGTGCGGAC
GCGAACCGATCGACTGGCAAATCGAAAACATCGGCGCCCGCGCCGAATGA

Upstream 100 bases:

>100_bases
ATAAGGTTGTCCACCCCTAAGACGTTTACAATGGATATACCCATATTTTATACTATTTGAAACAGAAAAGAAAAAAGCCA
ATGCCAAAGGAGTGGCTGCA

Downstream 100 bases:

>100_bases
ACAAGGAGGAAACACCATGTCCATTTCTTTTGCTGCTGTTGTCGCCAAAATGGAAGACGAGCTTCGGAAAGCGAAAGTTA
CGAACGACCCGCAGCGGATG

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MPILKNDWAPLLEEEFQKPYYLKLREFLKEEYRTRTIYPDMYDIFNALHYTPYANVKVVLLGQDPYHGPGQAHGLSFSVK
PGVPVPPSLVNIFKELHDDLGCYIPDNGYLVKWAKQGVLLLNTVLTVRRGQANSHRGKGWEHFTDRVIELVNEKDDPVVF
LLWGRNAQEKKERITNPRHHIIEAPHPSPFSAARGFFGHRPFSRTNAFLTKCGREPIDWQIENIGARAE

Sequences:

>Translated_229_residues
MPILKNDWAPLLEEEFQKPYYLKLREFLKEEYRTRTIYPDMYDIFNALHYTPYANVKVVLLGQDPYHGPGQAHGLSFSVK
PGVPVPPSLVNIFKELHDDLGCYIPDNGYLVKWAKQGVLLLNTVLTVRRGQANSHRGKGWEHFTDRVIELVNEKDDPVVF
LLWGRNAQEKKERITNPRHHIIEAPHPSPFSAARGFFGHRPFSRTNAFLTKCGREPIDWQIENIGARAE
>Mature_228_residues
PILKNDWAPLLEEEFQKPYYLKLREFLKEEYRTRTIYPDMYDIFNALHYTPYANVKVVLLGQDPYHGPGQAHGLSFSVKP
GVPVPPSLVNIFKELHDDLGCYIPDNGYLVKWAKQGVLLLNTVLTVRRGQANSHRGKGWEHFTDRVIELVNEKDDPVVFL
LWGRNAQEKKERITNPRHHIIEAPHPSPFSAARGFFGHRPFSRTNAFLTKCGREPIDWQIENIGARAE

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=215, Percent_Identity=53.4883720930233, Blast_Score=233, Evalue=1e-61,
Organism=Homo sapiens, GI6224979, Length=215, Percent_Identity=53.4883720930233, Blast_Score=233, Evalue=1e-61,
Organism=Escherichia coli, GI1788934, Length=214, Percent_Identity=56.5420560747664, Blast_Score=247, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI17556304, Length=216, Percent_Identity=47.2222222222222, Blast_Score=202, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6323620, Length=238, Percent_Identity=45.3781512605042, Blast_Score=201, Evalue=7e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 26459; Mature: 26327

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPILKNDWAPLLEEEFQKPYYLKLREFLKEEYRTRTIYPDMYDIFNALHYTPYANVKVVL
CCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEE
LGQDPYHGPGQAHGLSFSVKPGVPVPPSLVNIFKELHDDLGCYIPDNGYLVKWAKQGVLL
EECCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCEEECCCCEEEEEECCCCHH
LNTVLTVRRGQANSHRGKGWEHFTDRVIELVNEKDDPVVFLLWGRNAQEKKERITNPRHH
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCCHHE
IIEAPHPSPFSAARGFFGHRPFSRTNAFLTKCGREPIDWQIENIGARAE
EEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
PILKNDWAPLLEEEFQKPYYLKLREFLKEEYRTRTIYPDMYDIFNALHYTPYANVKVVL
CCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEE
LGQDPYHGPGQAHGLSFSVKPGVPVPPSLVNIFKELHDDLGCYIPDNGYLVKWAKQGVLL
EECCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCEEECCCCEEEEEECCCCHH
LNTVLTVRRGQANSHRGKGWEHFTDRVIELVNEKDDPVVFLLWGRNAQEKKERITNPRHH
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCCHHE
IIEAPHPSPFSAARGFFGHRPFSRTNAFLTKCGREPIDWQIENIGARAE
EEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA