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The map label for this gene is rsbU [H]

Identifier: 138897002

GI number: 138897002

Start: 3477618

End: 3479498

Strand: Reverse

Name: rsbU [H]

Synonym: GTNG_3373

Alternate gene names: 138897002

Gene position: 3479498-3477618 (Counterclockwise)

Preceding gene: 138897003

Following gene: 138896998

Centisome position: 98.01

GC content: 52.79

Gene sequence:

>1881_bases
ATGCGCCTGCACAGCATAGCGGCAGTGTTGGCAACCACGTTATTTGGCGTGCTTTTGTTCGCTGCAGGGCGGCTCTCTTT
TCCCCCTAGTTTCTATCATTCTATTCATCTTGCTTTAGGGCTTGCCGCCGTTGTCGTCTGCTGGCTTGTCGCCATGCAAG
GATGGGCGGTGTTTCCCCATACGCTGTCGATGGAGCGGCTCGTGATGGGGGCGTTATTTTTTTCCTCAGGATCGCTGTTT
TCCTTTCATTTTCTCCTTTCATTCGCGGACGCGGGTGAAGCGTCGCTGTTTTCGCTTGCTGCTCGCTTTACGATCGCTTG
GGGGTTGCTCTTTTTATTTTCACGTCCGGACGAGGTGATGGAACGGCACAGCGGACAGCGTTGGCAGGCGTTTTTGATGG
CCTTGGTTTATACAGCTGCTATCGGTCTATTGCTCCATTTTACAGCGTCGCTTTGGCTGGGAGATGGGACGAGCCGCTGG
CCGCTTTGGTGGCAGGCGGGAGAAGGGACGGTTGGATTGCTTGATGCAGCAGCCGCCGCGATCGTATGGCGTCGCTATCG
GCAAGGCGGCTCTTCTTCCCCCTTGTACTGGTTGATGGCTTTACTGTTGTTCGCTTTTGGCCAAGTGTTGCTGATGTTGG
GCCCTGGGCATGTGCTATGGGGGCAGCTGTACGAAGTGGCCGGATTTTTGTATGTCTTGCGGGCTATGTATGTGGAGACG
ATTGAAAAGCCGTATGTAGAACTCAAGCAACACGAACAGCAGCTGGAAATGATGGCGAACGCCCTTGGCGAAGGACTGAT
GATGTTAGACCGAGACGGGCAAATTGTTTGGATGAACCCAGAAGCCGGTCGACTGCTCGGTGTCGTCCCTGACGAAGCGA
AAGGAAAGCCGTTATTTTCTTTTGTTTCGCTTGCTGGGCCGAACGGTGACGCATGGGATTGGAAGCAGCTGCGCTACGTC
GTCAAACGGTTGAAAAGCGGCGAAGTGATCCGCGTTGAGGAAGAGTCATTTTGCCGATACGACGGTGTTTGTTTGCCGGT
GAGCTACACGCTGGCGCCAGTAATCGAAAACGGTGCGCTGACGGGGCTTGTCGCTGTGTTGCGCGACATGACGGAGAAAA
AAGAGAAAGAGCGGCTTGAACGAGAGCGTGAACAGCTTGATTTTGAATTGTCGCTTGCAGCGAATATGCAGCGTGCGCTC
TTGCAGACGTCTTCCGAAGCGAATTTGCCATCCTATGTCGACATCGGTGTCCTCAGCGTTCCCGCTCGGGTATTAAGCGG
CGATTTTTACCGCTTTTCTGTTCACCAAACATCCGTGTCTGTCGGCATTGCTGATGTGTCGGGAAAAGGCATTCCAGCCG
CAATGCTTATGACACTAATGAAATTTATTTTAGACCGCACGGTCCATTATGGGACGCAGCCGCATGTGTATCTTGACTTG
TTGAATCGGTTCGCCTATGACTACACCGAACCGTCAATGTTTGTAACGATGTTTGTCGGCAATTACAATGAAAAAACGCA
CGTATTTTCGTATGCGTGCGCCGGGCATGAGCCGGCGCTTCTATACCGAGCGAAAACGAAACAATGCGTGCCGCTTCACG
CCAAAGGATGCGCGCTCGGCTTGTTCCCGCAATTTTCGTTTGAGACCAAATCGGTTGCACTAGAACCAGGAGATTTTGTG
TTGTTGTACACGGACGGAGTGACGGAAAAGCGCGGGGAAGAAGTGGCTGATGGCTTTTCTGTCCTCGCCTCAATGGTCAC
CCGCACCAACCTCGACCAGCCTGCCTCACAAGTTGTTCACGATTTGTACGAGCAGGTGAAAGCGTATCACCAATACGAAC
AAAAAGACGATCAGACGTTGTTGCTATTGCGCCGCCGTTGA

Upstream 100 bases:

>100_bases
ACGTTCCTATACGTCAGTTAGATGACGTATGGTATAATAAACCATATAAACAAAGAGTGGGGGTTCACCATTTGTGAACG
AACATAGACAAAATCGGCAA

Downstream 100 bases:

>100_bases
CATCAGCGTTTATACTGCTTGATGGTGAAGGCGGCGCTTTCTTCTGCCATTATGACGAATAGGCGGCAAGCTGCCGCTTC
AGTTTTTCAATCGCCCGCTT

Product: putative sigma-B regulator

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 626; Mature: 626

Protein sequence:

>626_residues
MRLHSIAAVLATTLFGVLLFAAGRLSFPPSFYHSIHLALGLAAVVVCWLVAMQGWAVFPHTLSMERLVMGALFFSSGSLF
SFHFLLSFADAGEASLFSLAARFTIAWGLLFLFSRPDEVMERHSGQRWQAFLMALVYTAAIGLLLHFTASLWLGDGTSRW
PLWWQAGEGTVGLLDAAAAAIVWRRYRQGGSSSPLYWLMALLLFAFGQVLLMLGPGHVLWGQLYEVAGFLYVLRAMYVET
IEKPYVELKQHEQQLEMMANALGEGLMMLDRDGQIVWMNPEAGRLLGVVPDEAKGKPLFSFVSLAGPNGDAWDWKQLRYV
VKRLKSGEVIRVEEESFCRYDGVCLPVSYTLAPVIENGALTGLVAVLRDMTEKKEKERLEREREQLDFELSLAANMQRAL
LQTSSEANLPSYVDIGVLSVPARVLSGDFYRFSVHQTSVSVGIADVSGKGIPAAMLMTLMKFILDRTVHYGTQPHVYLDL
LNRFAYDYTEPSMFVTMFVGNYNEKTHVFSYACAGHEPALLYRAKTKQCVPLHAKGCALGLFPQFSFETKSVALEPGDFV
LLYTDGVTEKRGEEVADGFSVLASMVTRTNLDQPASQVVHDLYEQVKAYHQYEQKDDQTLLLLRRR

Sequences:

>Translated_626_residues
MRLHSIAAVLATTLFGVLLFAAGRLSFPPSFYHSIHLALGLAAVVVCWLVAMQGWAVFPHTLSMERLVMGALFFSSGSLF
SFHFLLSFADAGEASLFSLAARFTIAWGLLFLFSRPDEVMERHSGQRWQAFLMALVYTAAIGLLLHFTASLWLGDGTSRW
PLWWQAGEGTVGLLDAAAAAIVWRRYRQGGSSSPLYWLMALLLFAFGQVLLMLGPGHVLWGQLYEVAGFLYVLRAMYVET
IEKPYVELKQHEQQLEMMANALGEGLMMLDRDGQIVWMNPEAGRLLGVVPDEAKGKPLFSFVSLAGPNGDAWDWKQLRYV
VKRLKSGEVIRVEEESFCRYDGVCLPVSYTLAPVIENGALTGLVAVLRDMTEKKEKERLEREREQLDFELSLAANMQRAL
LQTSSEANLPSYVDIGVLSVPARVLSGDFYRFSVHQTSVSVGIADVSGKGIPAAMLMTLMKFILDRTVHYGTQPHVYLDL
LNRFAYDYTEPSMFVTMFVGNYNEKTHVFSYACAGHEPALLYRAKTKQCVPLHAKGCALGLFPQFSFETKSVALEPGDFV
LLYTDGVTEKRGEEVADGFSVLASMVTRTNLDQPASQVVHDLYEQVKAYHQYEQKDDQTLLLLRRR
>Mature_626_residues
MRLHSIAAVLATTLFGVLLFAAGRLSFPPSFYHSIHLALGLAAVVVCWLVAMQGWAVFPHTLSMERLVMGALFFSSGSLF
SFHFLLSFADAGEASLFSLAARFTIAWGLLFLFSRPDEVMERHSGQRWQAFLMALVYTAAIGLLLHFTASLWLGDGTSRW
PLWWQAGEGTVGLLDAAAAAIVWRRYRQGGSSSPLYWLMALLLFAFGQVLLMLGPGHVLWGQLYEVAGFLYVLRAMYVET
IEKPYVELKQHEQQLEMMANALGEGLMMLDRDGQIVWMNPEAGRLLGVVPDEAKGKPLFSFVSLAGPNGDAWDWKQLRYV
VKRLKSGEVIRVEEESFCRYDGVCLPVSYTLAPVIENGALTGLVAVLRDMTEKKEKERLEREREQLDFELSLAANMQRAL
LQTSSEANLPSYVDIGVLSVPARVLSGDFYRFSVHQTSVSVGIADVSGKGIPAAMLMTLMKFILDRTVHYGTQPHVYLDL
LNRFAYDYTEPSMFVTMFVGNYNEKTHVFSYACAGHEPALLYRAKTKQCVPLHAKGCALGLFPQFSFETKSVALEPGDFV
LLYTDGVTEKRGEEVADGFSVLASMVTRTNLDQPASQVVHDLYEQVKAYHQYEQKDDQTLLLLRRR

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 69994; Mature: 69994

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS50112 PAS ; PS50113 PAC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLHSIAAVLATTLFGVLLFAAGRLSFPPSFYHSIHLALGLAAVVVCWLVAMQGWAVFPH
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCC
TLSMERLVMGALFFSSGSLFSFHFLLSFADAGEASLFSLAARFTIAWGLLFLFSRPDEVM
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
ERHSGQRWQAFLMALVYTAAIGLLLHFTASLWLGDGTSRWPLWWQAGEGTVGLLDAAAAA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEECCCCCCHHHHHHHHH
IVWRRYRQGGSSSPLYWLMALLLFAFGQVLLMLGPGHVLWGQLYEVAGFLYVLRAMYVET
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
IEKPYVELKQHEQQLEMMANALGEGLMMLDRDGQIVWMNPEAGRLLGVVPDEAKGKPLFS
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCCEEEECCCCCCCCHHHH
FVSLAGPNGDAWDWKQLRYVVKRLKSGEVIRVEEESFCRYDGVCLPVSYTLAPVIENGAL
HHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEHHHHHHHHHCCCHH
TGLVAVLRDMTEKKEKERLEREREQLDFELSLAANMQRALLQTSSEANLPSYVDIGVLSV
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHCCCCCCCCCEEECHHHHH
PARVLSGDFYRFSVHQTSVSVGIADVSGKGIPAAMLMTLMKFILDRTVHYGTQPHVYLDL
HHHHHCCCEEEEEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LNRFAYDYTEPSMFVTMFVGNYNEKTHVFSYACAGHEPALLYRAKTKQCVPLHAKGCALG
HHHHHCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCEEE
LFPQFSFETKSVALEPGDFVLLYTDGVTEKRGEEVADGFSVLASMVTRTNLDQPASQVVH
CCCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
DLYEQVKAYHQYEQKDDQTLLLLRRR
HHHHHHHHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure
MRLHSIAAVLATTLFGVLLFAAGRLSFPPSFYHSIHLALGLAAVVVCWLVAMQGWAVFPH
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCC
TLSMERLVMGALFFSSGSLFSFHFLLSFADAGEASLFSLAARFTIAWGLLFLFSRPDEVM
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
ERHSGQRWQAFLMALVYTAAIGLLLHFTASLWLGDGTSRWPLWWQAGEGTVGLLDAAAAA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEECCCCCCHHHHHHHHH
IVWRRYRQGGSSSPLYWLMALLLFAFGQVLLMLGPGHVLWGQLYEVAGFLYVLRAMYVET
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
IEKPYVELKQHEQQLEMMANALGEGLMMLDRDGQIVWMNPEAGRLLGVVPDEAKGKPLFS
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCCEEEECCCCCCCCHHHH
FVSLAGPNGDAWDWKQLRYVVKRLKSGEVIRVEEESFCRYDGVCLPVSYTLAPVIENGAL
HHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEHHHHHHHHHCCCHH
TGLVAVLRDMTEKKEKERLEREREQLDFELSLAANMQRALLQTSSEANLPSYVDIGVLSV
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHCCCCCCCCCEEECHHHHH
PARVLSGDFYRFSVHQTSVSVGIADVSGKGIPAAMLMTLMKFILDRTVHYGTQPHVYLDL
HHHHHCCCEEEEEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LNRFAYDYTEPSMFVTMFVGNYNEKTHVFSYACAGHEPALLYRAKTKQCVPLHAKGCALG
HHHHHCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCEEE
LFPQFSFETKSVALEPGDFVLLYTDGVTEKRGEEVADGFSVLASMVTRTNLDQPASQVVH
CCCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
DLYEQVKAYHQYEQKDDQTLLLLRRR
HHHHHHHHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]