Click here to switch to the map view.

The map label for this gene is nuoI [H]

Identifier: 138896928

GI number: 138896928

Start: 3407011

End: 3407430

Strand: Reverse

Name: nuoI [H]

Synonym: GTNG_3297

Alternate gene names: 138896928

Gene position: 3407430-3407011 (Counterclockwise)

Preceding gene: 138896929

Following gene: 138896927

Centisome position: 95.98

GC content: 45.71

Gene sequence:

>420_bases
ATGATCGGGTTAGTAAAAGGATTAGCGTATACGTTAAAAGAATTGACGCGCGAAAAAGTAACGTACAAGTACCCGCATGA
GCCGCTCCCGCTCCCGGACCGGTTTCGCGGCATCCAAAAATTTTATCCGGAAAAATGCATCGTCTGCAATCAGTGCATGA
ACATTTGTCCGACGCAATGCATTCAGCTGACCGGGAAAAAACATCCCGATCCGACGAAAAAAGGGAAAGTGATCGAGACG
TACAACATTAACTTTGAAATTTGCATTTTATGCGACTTATGCACGGAAGTTTGCCCGACGGAAGCGATTGTCATGACGAA
CAACTTCGAACTCGCTGAATACAGCCGTGATGCCCTGTATAAAGATTTGACTTGGCTCGATGAAAACGACACGAACGTAA
GAAGGGAGAATAAGCCGTGA

Upstream 100 bases:

>100_bases
CCTGCCTTGTGAGAGAGGCGGTCGTTATCCATAGGCACGGCTTCTTTCAAGGCAAGAGGCCGTGCAGAACGCCATTTTTC
CCATGAGAGGGGTTGGACGG

Downstream 100 bases:

>100_bases
GCGGAACCGACATTGCCTTTTTCCTGCTTGCCCTTGCAGCCATTGCTGGCGGGGTGACGATGCTTCAACTGACGAACGTC
GTCCATATGGTGATCGCCCT

Product: NADH dehydrogenase subunit I

Products: NA

Alternate protein names: NADH dehydrogenase I subunit I; NDH-1 subunit I [H]

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MIGLVKGLAYTLKELTREKVTYKYPHEPLPLPDRFRGIQKFYPEKCIVCNQCMNICPTQCIQLTGKKHPDPTKKGKVIET
YNINFEICILCDLCTEVCPTEAIVMTNNFELAEYSRDALYKDLTWLDENDTNVRRENKP

Sequences:

>Translated_139_residues
MIGLVKGLAYTLKELTREKVTYKYPHEPLPLPDRFRGIQKFYPEKCIVCNQCMNICPTQCIQLTGKKHPDPTKKGKVIET
YNINFEICILCDLCTEVCPTEAIVMTNNFELAEYSRDALYKDLTWLDENDTNVRRENKP
>Mature_139_residues
MIGLVKGLAYTLKELTREKVTYKYPHEPLPLPDRFRGIQKFYPEKCIVCNQCMNICPTQCIQLTGKKHPDPTKKGKVIET
YNINFEICILCDLCTEVCPTEAIVMTNNFELAEYSRDALYKDLTWLDENDTNVRRENKP

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI4505371, Length=133, Percent_Identity=38.3458646616541, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1788617, Length=108, Percent_Identity=42.5925925925926, Blast_Score=79, Evalue=1e-16,
Organism=Escherichia coli, GI1789075, Length=98, Percent_Identity=32.6530612244898, Blast_Score=63, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17555194, Length=121, Percent_Identity=37.1900826446281, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17864306, Length=121, Percent_Identity=37.1900826446281, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR010226 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 16167; Mature: 16167

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
8.6 %Cys+Met (Translated Protein)
6.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
8.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGLVKGLAYTLKELTREKVTYKYPHEPLPLPDRFRGIQKFYPEKCIVCNQCMNICPTQC
CCCHHHHHHHHHHHHHHHHCEEECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHH
IQLTGKKHPDPTKKGKVIETYNINFEICILCDLCTEVCPTEAIVMTNNFELAEYSRDALY
HHHCCCCCCCCCCCCCEEEEEECCEEEEEHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
KDLTWLDENDTNVRRENKP
HHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIGLVKGLAYTLKELTREKVTYKYPHEPLPLPDRFRGIQKFYPEKCIVCNQCMNICPTQC
CCCHHHHHHHHHHHHHHHHCEEECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHH
IQLTGKKHPDPTKKGKVIETYNINFEICILCDLCTEVCPTEAIVMTNNFELAEYSRDALY
HHHCCCCCCCCCCCCCEEEEEECCEEEEEHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
KDLTWLDENDTNVRRENKP
HHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA