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The map label for this gene is nuoH [H]

Identifier: 138896929

GI number: 138896929

Start: 3407542

End: 3408540

Strand: Reverse

Name: nuoH [H]

Synonym: GTNG_3298

Alternate gene names: 138896929

Gene position: 3408540-3407542 (Counterclockwise)

Preceding gene: 138896930

Following gene: 138896928

Centisome position: 96.01

GC content: 52.95

Gene sequence:

>999_bases
ATGGAACAATGGCTCGAATCGGCGCCAGGCTGGACGAATGTCGCCGTCTTCTTCGGGCTTGGGGCGCTTTTGCTGCTAGT
CGTGCTCGGGTTCGTCACATACGCCATTTTGGCGGAACGGAAAGTGATGGGATTTATGCAAGGGCGCATCGGCCCGAACC
AAGTTGGCGGCCGTCTAGGGCTGTTGCAAACGGTCGCTGACGTATTAAAGCTGCTGTTAAAGGAAGATACAATTCCGAAA
GCGGCTGACCGCCCGCTGTACGTGTTGGCGCCGATCATCGCCTTTACGCCGTCATTTATGGTGTTGGCGGCGCTGCCGTT
TACCGATGCGTTCCGATTTGCCGATATCGGCGTTGGCCTATTGTACTATATTGCTGTTTCTGGATTAACCACGATCGGCG
TTGTCACCGGCGGCTGGGCATCCAACAACAAATACGCCTTGCTTGGCGGCATGCGCGCGGCAGCGCAAATGATTTCATAC
GAAATTCCGCTCGTCATGTCGGCGCTTGGCGTCGTGCTCTTGGCTGGAAGCATGAATTTGGTCGACATTGTCACAGCGCA
AGACAACGTTTGGTTTATTTTTGCCCAACCGCTCGCCTTCTTGATCTTCTTTATTGCTGCAGTGGCTGAGTTGAATCGGG
TGCCGTTTGACTTACCGGAGGCGGAATCTGAGCTTGTTTCCGGATTTCACGTCGAATATTCCGGATTCCGTTGGGCGTTC
TTTATGCTTGCTGAGTATGTCTATTTGTTTGCGATGGCCGCTTTGATTACGATTTTGTTTTTAGGCGGTTGGCACCCAGT
TGCGTTTCTCGGCTGGATTCCTGGCTCTGTCTGGTTTGCGCTTAAGTTTTGTGCCATCGTCTATGTCTTGATCTGGTTTC
GCGCGACGTTCCCGCGCGTGCGCGCCGACCAGCTGATGGAGTTTGCCTGGAAAGTGCTGCTTCCGCTTTCGCTCGTCAAC
ATCGTGTTGACGGCTGTGATTAAATCGTTATTCTTCTAA

Upstream 100 bases:

>100_bases
ACTTGCAAATACTCCCGAAGCTGCTTAAAGGAGAAAATTTGGCCAACGTCATCGCCATTCTCGGATCGATTGACATTGTG
CTCGGGGAGGTCGACGGATA

Downstream 100 bases:

>100_bases
AAAATGAGGCGCCTGCCTTGTGAGAGAGGCGGTCGTTATCCATAGGCACGGCTTCTTTCAAGGCAAGAGGCCGTGCAGAA
CGCCATTTTTCCCATGAGAG

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MEQWLESAPGWTNVAVFFGLGALLLLVVLGFVTYAILAERKVMGFMQGRIGPNQVGGRLGLLQTVADVLKLLLKEDTIPK
AADRPLYVLAPIIAFTPSFMVLAALPFTDAFRFADIGVGLLYYIAVSGLTTIGVVTGGWASNNKYALLGGMRAAAQMISY
EIPLVMSALGVVLLAGSMNLVDIVTAQDNVWFIFAQPLAFLIFFIAAVAELNRVPFDLPEAESELVSGFHVEYSGFRWAF
FMLAEYVYLFAMAALITILFLGGWHPVAFLGWIPGSVWFALKFCAIVYVLIWFRATFPRVRADQLMEFAWKVLLPLSLVN
IVLTAVIKSLFF

Sequences:

>Translated_332_residues
MEQWLESAPGWTNVAVFFGLGALLLLVVLGFVTYAILAERKVMGFMQGRIGPNQVGGRLGLLQTVADVLKLLLKEDTIPK
AADRPLYVLAPIIAFTPSFMVLAALPFTDAFRFADIGVGLLYYIAVSGLTTIGVVTGGWASNNKYALLGGMRAAAQMISY
EIPLVMSALGVVLLAGSMNLVDIVTAQDNVWFIFAQPLAFLIFFIAAVAELNRVPFDLPEAESELVSGFHVEYSGFRWAF
FMLAEYVYLFAMAALITILFLGGWHPVAFLGWIPGSVWFALKFCAIVYVLIWFRATFPRVRADQLMEFAWKVLLPLSLVN
IVLTAVIKSLFF
>Mature_332_residues
MEQWLESAPGWTNVAVFFGLGALLLLVVLGFVTYAILAERKVMGFMQGRIGPNQVGGRLGLLQTVADVLKLLLKEDTIPK
AADRPLYVLAPIIAFTPSFMVLAALPFTDAFRFADIGVGLLYYIAVSGLTTIGVVTGGWASNNKYALLGGMRAAAQMISY
EIPLVMSALGVVLLAGSMNLVDIVTAQDNVWFIFAQPLAFLIFFIAAVAELNRVPFDLPEAESELVSGFHVEYSGFRWAF
FMLAEYVYLFAMAALITILFLGGWHPVAFLGWIPGSVWFALKFCAIVYVLIWFRATFPRVRADQLMEFAWKVLLPLSLVN
IVLTAVIKSLFF

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=285, Percent_Identity=40.3508771929825, Blast_Score=203, Evalue=2e-52,
Organism=Escherichia coli, GI1788618, Length=306, Percent_Identity=44.7712418300654, Blast_Score=269, Evalue=2e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 36559; Mature: 36559

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQWLESAPGWTNVAVFFGLGALLLLVVLGFVTYAILAERKVMGFMQGRIGPNQVGGRLG
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHH
LLQTVADVLKLLLKEDTIPKAADRPLYVLAPIIAFTPSFMVLAALPFTDAFRFADIGVGL
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHH
LYYIAVSGLTTIGVVTGGWASNNKYALLGGMRAAAQMISYEIPLVMSALGVVLLAGSMNL
HHHHHHHHHHHHHEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VDIVTAQDNVWFIFAQPLAFLIFFIAAVAELNRVPFDLPEAESELVSGFHVEYSGFRWAF
EEEEEECCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCEEECCHHHHH
FMLAEYVYLFAMAALITILFLGGWHPVAFLGWIPGSVWFALKFCAIVYVLIWFRATFPRV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCC
RADQLMEFAWKVLLPLSLVNIVLTAVIKSLFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEQWLESAPGWTNVAVFFGLGALLLLVVLGFVTYAILAERKVMGFMQGRIGPNQVGGRLG
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHH
LLQTVADVLKLLLKEDTIPKAADRPLYVLAPIIAFTPSFMVLAALPFTDAFRFADIGVGL
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHH
LYYIAVSGLTTIGVVTGGWASNNKYALLGGMRAAAQMISYEIPLVMSALGVVLLAGSMNL
HHHHHHHHHHHHHEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VDIVTAQDNVWFIFAQPLAFLIFFIAAVAELNRVPFDLPEAESELVSGFHVEYSGFRWAF
EEEEEECCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCEEECCHHHHH
FMLAEYVYLFAMAALITILFLGGWHPVAFLGWIPGSVWFALKFCAIVYVLIWFRATFPRV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCC
RADQLMEFAWKVLLPLSLVNIVLTAVIKSLFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA