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The map label for this gene is rnr [H]

Identifier: 138896635

GI number: 138896635

Start: 3093849

End: 3096116

Strand: Reverse

Name: rnr [H]

Synonym: GTNG_2998

Alternate gene names: 138896635

Gene position: 3096116-3093849 (Counterclockwise)

Preceding gene: 138896636

Following gene: 138896634

Centisome position: 87.21

GC content: 52.34

Gene sequence:

>2268_bases
ATGGATCACGCATTGGCCGAACGAATTTTAACGTTTATGCGCGACGAGGCGTACAAGCCGCTGACAGTTCAAGAGCTCGA
AGAAGCGTTTGGGATCACGGAGGCGGACGAATTTAAAACGTTCGTTAAAACGCTTGTCGCCATGGAAGAGGAAGGGCTTG
TCGTTCGGACACGCAGCAACCGCTACGGTGTGCCTGAACGGATGAATCTCGTGCGCGGTAAAGTGACTGGCCATGCGAAA
GGATTTGCCTTCGTCACGCCGGAAGAACCGGGAATGGACGACATTTTCATCCCGCCGTCGGAGCTGAAAAATGCCATGCA
CGGCGACACGGTGCTCGTACGCGTCCAATCCGAGTCCGGCGGAGCGCGCCGCGAAGGGACGATCGTCCGCATTTTGGAGC
GTGGGGTGAAAGAAGTCGTCGGTACATATACGGAAAGCAAATATTTCGGCTTTGTCATCCCCGATGATAAGCGGATCGTC
AACGATATTTTCATCCCGAAAAACGCGGCGAACGGGGCGGTCGAAGGGCATAAAGTCGTCGTCCGGCTCACATCATACCC
GGAAGGACGAATGAGCGCCGAAGGGGAAGTCGTCCAAATTCTTGGCCATAAAAACGACCCGGGCGTCGATATTTTATCGG
TCATCTATAAGCACGGCTTACCGCTTCAGTTTCCGGATGATGTCATCGATCATGCCAATCGTGTTCCTGATGTGATTACG
GAAAAGGATCTCGAGGGGCGCCGCGACTTGCGCGGTGAGATGATCGTCACCATCGACGGCGAAGATGCGAAAGACTTGGA
CGATGCGGTGACCGTGACAAAACTTGAGAACGGAAACTATAAACTGGGCGTCCATATTGCCGATGTGAGCCATTATGTCG
AAGAAGGCTCGCCGATTGACCGCGAAGCGTACGAACGCGGAACGAGCGTCTATTTGGTCGATCGTGTCATTCCGATGATT
CCGCACCGGTTGTCGAACGGCATTTGCTCGCTCAACCCGAAAGTCGACCGGTTGACGCTATCGTGTGAAATGGAAATCAC
CCCGCAAGGCGAAGTCGTCAGTCATGACATTTTCCAGAGCGTCATCCGCACGACGGAACGGATGACATATTCTGACGTCA
ATAAAATTTTGGTCGATAAAGATGAGGCGTTGCGTGAAAAATACGCGCCGCTTGTGCCGATGTTTGAACTCATGGCTGAG
CTCGCCGACATTTTGCGAACGAAGCGGATGAAGCGCGGGGCGATCGATTTCGATTTTAAAGAAGCGAAAGTGCTCGTTGA
TGAAAACGGCAAGCCATATGACGTCGTTTTGCGCGAGCGATCCGTTGCCGAGCGGCTCATTGAAGAGTTTATGTTGGTGG
CGAACGAAACGGTCGCCGAGCATTTCCATTGGCTCAACGTGCCGTTTATGTACCGCGTCCATGAGGATCCGAAGCCGGAG
AAACTGCAGCGCTTTTTGGAATTCATTACGAACTTCGGCTATGTCGTCAAAGGGACGGGCAACCAAATCCATCCGCGCGC
CTTGCAGCAAATTCTCGAAGCGGTGCGCGGCGAACCGGAAGAAATGGTCATTTCCACCGTCATGCTCCGGTCGATGAAGC
AAGCCCGTTATGACGCGGAAAGCCTTGGCCATTATGGCTTGTCCACCGAGTTTTACACCCATTTTACGTCCCCGATCCGC
CGCTATCCGGACTTAATCGTCCACCGGTTGATTCGGACGTATCTCATTAACGGACAGATGGATCCTGACACCCAGCAAAA
ATGGGCGGAAAAGCTGCCTGACATCGCCGAACATGCGTCCAACATGGAACGGCGCGCCGTCGAGGCTGAGCGTGAAACCG
ATGACTTAAAGAAAACAGAGTTTATGGAAGATAAAATCGGGATGGAATTTGACGGCATCATTAGTTCCGTCACGAACTTC
GGTTTGTTTGTGGAGCTCCCGAATACGATCGAAGGGTTGGTGCACGTCAGCTATTTAACGGATGATTATTACCGTTACGA
TGAGCGCAACTATGCCATGGTCGGCGAGCGGACGGGGAAAATGTACCGCATCGGTGATGAAATTACCGTCCGCGTCATTA
ACGTCAACAAAGACGAACGAATCGTTGATTTTGAAATCGTCGGCATGAAAGGGCGCCGCCCGCCGAAAGCGAAAGCGGCA
CCGGTTGTCATTGAAGGGAAAAAGCAAAAGAAAGCAAAGGCACAAGCGAAAAAGAACAACGCTGGCCGCCATACCAAAGC
GAAAAAGAAGAAAAAGAAAAAACGGTGA

Upstream 100 bases:

>100_bases
ATGTTATTACGCTTGATCAAGAAAAAGAGCAGCTGCATGAAGATATTTATGCGTTTCTTGAGTCGTTAGATTGGTAACGA
CGGAAAGGAGGAGAGGGCCG

Downstream 100 bases:

>100_bases
GGAAAAGCCGAGCAGGCGGCTTTTCCTTCTTTTTCGTTTTTGGTACAATAAAAGCGCTACGAATGAGGAGGAGGACGTTC
ATGCCAAAAGGGGAAGGAAA

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 755; Mature: 755

Protein sequence:

>755_residues
MDHALAERILTFMRDEAYKPLTVQELEEAFGITEADEFKTFVKTLVAMEEEGLVVRTRSNRYGVPERMNLVRGKVTGHAK
GFAFVTPEEPGMDDIFIPPSELKNAMHGDTVLVRVQSESGGARREGTIVRILERGVKEVVGTYTESKYFGFVIPDDKRIV
NDIFIPKNAANGAVEGHKVVVRLTSYPEGRMSAEGEVVQILGHKNDPGVDILSVIYKHGLPLQFPDDVIDHANRVPDVIT
EKDLEGRRDLRGEMIVTIDGEDAKDLDDAVTVTKLENGNYKLGVHIADVSHYVEEGSPIDREAYERGTSVYLVDRVIPMI
PHRLSNGICSLNPKVDRLTLSCEMEITPQGEVVSHDIFQSVIRTTERMTYSDVNKILVDKDEALREKYAPLVPMFELMAE
LADILRTKRMKRGAIDFDFKEAKVLVDENGKPYDVVLRERSVAERLIEEFMLVANETVAEHFHWLNVPFMYRVHEDPKPE
KLQRFLEFITNFGYVVKGTGNQIHPRALQQILEAVRGEPEEMVISTVMLRSMKQARYDAESLGHYGLSTEFYTHFTSPIR
RYPDLIVHRLIRTYLINGQMDPDTQQKWAEKLPDIAEHASNMERRAVEAERETDDLKKTEFMEDKIGMEFDGIISSVTNF
GLFVELPNTIEGLVHVSYLTDDYYRYDERNYAMVGERTGKMYRIGDEITVRVINVNKDERIVDFEIVGMKGRRPPKAKAA
PVVIEGKKQKKAKAQAKKNNAGRHTKAKKKKKKKR

Sequences:

>Translated_755_residues
MDHALAERILTFMRDEAYKPLTVQELEEAFGITEADEFKTFVKTLVAMEEEGLVVRTRSNRYGVPERMNLVRGKVTGHAK
GFAFVTPEEPGMDDIFIPPSELKNAMHGDTVLVRVQSESGGARREGTIVRILERGVKEVVGTYTESKYFGFVIPDDKRIV
NDIFIPKNAANGAVEGHKVVVRLTSYPEGRMSAEGEVVQILGHKNDPGVDILSVIYKHGLPLQFPDDVIDHANRVPDVIT
EKDLEGRRDLRGEMIVTIDGEDAKDLDDAVTVTKLENGNYKLGVHIADVSHYVEEGSPIDREAYERGTSVYLVDRVIPMI
PHRLSNGICSLNPKVDRLTLSCEMEITPQGEVVSHDIFQSVIRTTERMTYSDVNKILVDKDEALREKYAPLVPMFELMAE
LADILRTKRMKRGAIDFDFKEAKVLVDENGKPYDVVLRERSVAERLIEEFMLVANETVAEHFHWLNVPFMYRVHEDPKPE
KLQRFLEFITNFGYVVKGTGNQIHPRALQQILEAVRGEPEEMVISTVMLRSMKQARYDAESLGHYGLSTEFYTHFTSPIR
RYPDLIVHRLIRTYLINGQMDPDTQQKWAEKLPDIAEHASNMERRAVEAERETDDLKKTEFMEDKIGMEFDGIISSVTNF
GLFVELPNTIEGLVHVSYLTDDYYRYDERNYAMVGERTGKMYRIGDEITVRVINVNKDERIVDFEIVGMKGRRPPKAKAA
PVVIEGKKQKKAKAQAKKNNAGRHTKAKKKKKKKR
>Mature_755_residues
MDHALAERILTFMRDEAYKPLTVQELEEAFGITEADEFKTFVKTLVAMEEEGLVVRTRSNRYGVPERMNLVRGKVTGHAK
GFAFVTPEEPGMDDIFIPPSELKNAMHGDTVLVRVQSESGGARREGTIVRILERGVKEVVGTYTESKYFGFVIPDDKRIV
NDIFIPKNAANGAVEGHKVVVRLTSYPEGRMSAEGEVVQILGHKNDPGVDILSVIYKHGLPLQFPDDVIDHANRVPDVIT
EKDLEGRRDLRGEMIVTIDGEDAKDLDDAVTVTKLENGNYKLGVHIADVSHYVEEGSPIDREAYERGTSVYLVDRVIPMI
PHRLSNGICSLNPKVDRLTLSCEMEITPQGEVVSHDIFQSVIRTTERMTYSDVNKILVDKDEALREKYAPLVPMFELMAE
LADILRTKRMKRGAIDFDFKEAKVLVDENGKPYDVVLRERSVAERLIEEFMLVANETVAEHFHWLNVPFMYRVHEDPKPE
KLQRFLEFITNFGYVVKGTGNQIHPRALQQILEAVRGEPEEMVISTVMLRSMKQARYDAESLGHYGLSTEFYTHFTSPIR
RYPDLIVHRLIRTYLINGQMDPDTQQKWAEKLPDIAEHASNMERRAVEAERETDDLKKTEFMEDKIGMEFDGIISSVTNF
GLFVELPNTIEGLVHVSYLTDDYYRYDERNYAMVGERTGKMYRIGDEITVRVINVNKDERIVDFEIVGMKGRRPPKAKAA
PVVIEGKKQKKAKAQAKKNNAGRHTKAKKKKKKKR

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=542, Percent_Identity=30.0738007380074, Blast_Score=229, Evalue=1e-59,
Organism=Homo sapiens, GI190014623, Length=542, Percent_Identity=30.0738007380074, Blast_Score=228, Evalue=2e-59,
Organism=Homo sapiens, GI134288890, Length=458, Percent_Identity=32.7510917030568, Blast_Score=222, Evalue=1e-57,
Organism=Homo sapiens, GI19115966, Length=651, Percent_Identity=26.7281105990783, Blast_Score=186, Evalue=8e-47,
Organism=Homo sapiens, GI219521928, Length=651, Percent_Identity=26.7281105990783, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI156105695, Length=374, Percent_Identity=24.8663101604278, Blast_Score=76, Evalue=1e-13,
Organism=Escherichia coli, GI87082383, Length=696, Percent_Identity=40.5172413793103, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI1787542, Length=646, Percent_Identity=26.625386996904, Blast_Score=163, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17553506, Length=496, Percent_Identity=28.4274193548387, Blast_Score=199, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI212645896, Length=536, Percent_Identity=27.0522388059701, Blast_Score=174, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6324552, Length=528, Percent_Identity=29.5454545454545, Blast_Score=192, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6320499, Length=431, Percent_Identity=25.5220417633411, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323943, Length=363, Percent_Identity=25.068870523416, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24649634, Length=488, Percent_Identity=31.9672131147541, Blast_Score=225, Evalue=7e-59,
Organism=Drosophila melanogaster, GI19922976, Length=487, Percent_Identity=29.1581108829569, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24654597, Length=487, Percent_Identity=29.1581108829569, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24654592, Length=412, Percent_Identity=31.3106796116505, Blast_Score=187, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 86077; Mature: 86077

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHALAERILTFMRDEAYKPLTVQELEEAFGITEADEFKTFVKTLVAMEEEGLVVRTRSN
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCC
RYGVPERMNLVRGKVTGHAKGFAFVTPEEPGMDDIFIPPSELKNAMHGDTVLVRVQSESG
CCCCCHHHHHHHCCCCCCCCCEEEECCCCCCCCCEECCHHHHHHHCCCCEEEEEEECCCC
GARREGTIVRILERGVKEVVGTYTESKYFGFVIPDDKRIVNDIFIPKNAANGAVEGHKVV
CCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHEECCCCCCCCCCCCCEEE
VRLTSYPEGRMSAEGEVVQILGHKNDPGVDILSVIYKHGLPLQFPDDVIDHANRVPDVIT
EEEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHC
EKDLEGRRDLRGEMIVTIDGEDAKDLDDAVTVTKLENGNYKLGVHIADVSHYVEEGSPID
CCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCEEEEEEEEHHHHHHHCCCCCC
REAYERGTSVYLVDRVIPMIPHRLSNGICSLNPKVDRLTLSCEMEITPQGEVVSHDIFQS
HHHHHCCCEEEEHHHHHHHHHHHHCCCEEECCCCCEEEEEEEEEEECCCCCHHHHHHHHH
VIRTTERMTYSDVNKILVDKDEALREKYAPLVPMFELMAELADILRTKRMKRGAIDFDFK
HHHHHHHCCHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
EAKVLVDENGKPYDVVLRERSVAERLIEEFMLVANETVAEHFHWLNVPFMYRVHEDPKPE
CCEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHH
KLQRFLEFITNFGYVVKGTGNQIHPRALQQILEAVRGEPEEMVISTVMLRSMKQARYDAE
HHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHH
SLGHYGLSTEFYTHFTSPIRRYPDLIVHRLIRTYLINGQMDPDTQQKWAEKLPDIAEHAS
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHH
NMERRAVEAERETDDLKKTEFMEDKIGMEFDGIISSVTNFGLFVELPNTIEGLVHVSYLT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEECCCHHHHHEEEEEEC
DDYYRYDERNYAMVGERTGKMYRIGDEITVRVINVNKDERIVDFEIVGMKGRRPPKAKAA
CHHHHCCCCCEEEEECCCCCEEEECCEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCC
PVVIEGKKQKKAKAQAKKNNAGRHTKAKKKKKKKR
CEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MDHALAERILTFMRDEAYKPLTVQELEEAFGITEADEFKTFVKTLVAMEEEGLVVRTRSN
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCC
RYGVPERMNLVRGKVTGHAKGFAFVTPEEPGMDDIFIPPSELKNAMHGDTVLVRVQSESG
CCCCCHHHHHHHCCCCCCCCCEEEECCCCCCCCCEECCHHHHHHHCCCCEEEEEEECCCC
GARREGTIVRILERGVKEVVGTYTESKYFGFVIPDDKRIVNDIFIPKNAANGAVEGHKVV
CCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHEECCCCCCCCCCCCCEEE
VRLTSYPEGRMSAEGEVVQILGHKNDPGVDILSVIYKHGLPLQFPDDVIDHANRVPDVIT
EEEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHC
EKDLEGRRDLRGEMIVTIDGEDAKDLDDAVTVTKLENGNYKLGVHIADVSHYVEEGSPID
CCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCEEEEEEEEHHHHHHHCCCCCC
REAYERGTSVYLVDRVIPMIPHRLSNGICSLNPKVDRLTLSCEMEITPQGEVVSHDIFQS
HHHHHCCCEEEEHHHHHHHHHHHHCCCEEECCCCCEEEEEEEEEEECCCCCHHHHHHHHH
VIRTTERMTYSDVNKILVDKDEALREKYAPLVPMFELMAELADILRTKRMKRGAIDFDFK
HHHHHHHCCHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
EAKVLVDENGKPYDVVLRERSVAERLIEEFMLVANETVAEHFHWLNVPFMYRVHEDPKPE
CCEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHH
KLQRFLEFITNFGYVVKGTGNQIHPRALQQILEAVRGEPEEMVISTVMLRSMKQARYDAE
HHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHH
SLGHYGLSTEFYTHFTSPIRRYPDLIVHRLIRTYLINGQMDPDTQQKWAEKLPDIAEHAS
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHH
NMERRAVEAERETDDLKKTEFMEDKIGMEFDGIISSVTNFGLFVELPNTIEGLVHVSYLT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEECCCHHHHHEEEEEEC
DDYYRYDERNYAMVGERTGKMYRIGDEITVRVINVNKDERIVDFEIVGMKGRRPPKAKAA
CHHHHCCCCCEEEEECCCCCEEEECCEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCC
PVVIEGKKQKKAKAQAKKNNAGRHTKAKKKKKKKR
CEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]