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The map label for this gene is ilvC [H]

Identifier: 138896225

GI number: 138896225

Start: 2697280

End: 2698305

Strand: Reverse

Name: ilvC [H]

Synonym: GTNG_2588

Alternate gene names: 138896225

Gene position: 2698305-2697280 (Counterclockwise)

Preceding gene: 138896226

Following gene: 138896224

Centisome position: 76.0

GC content: 49.71

Gene sequence:

>1026_bases
ATGGCAAAAGTTTACTATAACGGAGATGCAAACGAACAATACTTGCAAGGAAAAACAGTTGCTATCATCGGCTATGGTTC
GCAAGGCCATGCCCATGCGCAAAATTTGCGTGACAGCGGTGTTCACGTCATTATCGGATTGCGGAAAGGCAGATCATGGG
AACAAGCGGAACAAGACGGCTTTGATGTATATTCGGTGCGTGAAGCGTCGAAAAAAGCTGATATCGTGATGGTGCTGCTG
CCAGATGAAAAGCAGCCCGCTGTTTACAAGGAAGAAATTGAACCAGAACTGAAACCGGGCAACGCGCTTGTCTTCGCCCA
TGGCTTTAATATTCATTTCAGCCAAATCGTCCCGCCGGAGCACGTTGACGTCTTTTTAGTCGCACCAAAAGGCCCAGGCC
ACCTCGTGCGTCGCACATACGTCGAAGGGGCGGGCGTACCAGCACTCATCGCCGTCTACCAAGATGTGACCGGCCATGCC
AAGGAAACGGCGCTCGCCTATGCCAAAGCGATCGGTGCCGCTCGGGCTGGAGTGCTTGAGACAACGTTCAAAGAAGAAAC
AGAAACTGACTTATTCGGCGAACAGGCGGTACTTTGCGGCGGATTGACGGCACTCATTAAAGCCGGATTTGAAACGCTTG
TTGAAGCTGGATATCAGCCGGAAGTCGCGTATTTCGAATGTTTGCATGAGATGAAGCTCATCGTCGATCTCCTTTATGAG
GGCGGACTGTCGTGGATGCGCTACTCGATTTCTGATACGGCACAATGGGGTGACTTTACATCCGGACCGCGTGTCATTAA
CGAAGCAGTAAAAGCAGAAATGAAAAACATCTTGCATGACATTCAAACCGGCAAATTTGCAAAAGGCTGGATTTTAGAAA
ATCAGGCGAATCGTCCAGAATTCAACGCCATCAACCAGCGCGAAAATGAGCATTTGATCGAGGTCGTCGGACGCGAATTG
CGGAGCATGATGCCGTTTGTGAAGGCAAAACAAAAAGAGGTGGTGGTGCCAGGTGCGAAAAATTAA

Upstream 100 bases:

>100_bases
AACGACTGCGTTTACCCGCGGGGCGCAAAAAGCGGGATCCAATCAGAAAACAGCATTCATCATTTAACAATTATTACACT
AATAAAAGGAGAGGGTAATC

Downstream 100 bases:

>100_bases
GTTTTTTGATACGACCTTGCGCGACGGGGAACAATCGGCTGGTGTCAACTTGAACTTGCAAGAAAAATTGGAGATCGCCC
GCCAGCTCGAGCGTCTGCAA

Product: ketol-acid reductoisomerase

Products: NA

Alternate protein names: Acetohydroxy-acid isomeroreductase; Alpha-keto-beta-hydroxylacil reductoisomerase [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MAKVYYNGDANEQYLQGKTVAIIGYGSQGHAHAQNLRDSGVHVIIGLRKGRSWEQAEQDGFDVYSVREASKKADIVMVLL
PDEKQPAVYKEEIEPELKPGNALVFAHGFNIHFSQIVPPEHVDVFLVAPKGPGHLVRRTYVEGAGVPALIAVYQDVTGHA
KETALAYAKAIGAARAGVLETTFKEETETDLFGEQAVLCGGLTALIKAGFETLVEAGYQPEVAYFECLHEMKLIVDLLYE
GGLSWMRYSISDTAQWGDFTSGPRVINEAVKAEMKNILHDIQTGKFAKGWILENQANRPEFNAINQRENEHLIEVVGREL
RSMMPFVKAKQKEVVVPGAKN

Sequences:

>Translated_341_residues
MAKVYYNGDANEQYLQGKTVAIIGYGSQGHAHAQNLRDSGVHVIIGLRKGRSWEQAEQDGFDVYSVREASKKADIVMVLL
PDEKQPAVYKEEIEPELKPGNALVFAHGFNIHFSQIVPPEHVDVFLVAPKGPGHLVRRTYVEGAGVPALIAVYQDVTGHA
KETALAYAKAIGAARAGVLETTFKEETETDLFGEQAVLCGGLTALIKAGFETLVEAGYQPEVAYFECLHEMKLIVDLLYE
GGLSWMRYSISDTAQWGDFTSGPRVINEAVKAEMKNILHDIQTGKFAKGWILENQANRPEFNAINQRENEHLIEVVGREL
RSMMPFVKAKQKEVVVPGAKN
>Mature_340_residues
AKVYYNGDANEQYLQGKTVAIIGYGSQGHAHAQNLRDSGVHVIIGLRKGRSWEQAEQDGFDVYSVREASKKADIVMVLLP
DEKQPAVYKEEIEPELKPGNALVFAHGFNIHFSQIVPPEHVDVFLVAPKGPGHLVRRTYVEGAGVPALIAVYQDVTGHAK
ETALAYAKAIGAARAGVLETTFKEETETDLFGEQAVLCGGLTALIKAGFETLVEAGYQPEVAYFECLHEMKLIVDLLYEG
GLSWMRYSISDTAQWGDFTSGPRVINEAVKAEMKNILHDIQTGKFAKGWILENQANRPEFNAINQRENEHLIEVVGRELR
SMMPFVKAKQKEVVVPGAKN

Specific function: Valine and isoleucine biosynthesis; second step. [C]

COG id: COG0059

COG function: function code EH; Ketol-acid reductoisomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketol-acid reductoisomerase family [H]

Homologues:

Organism=Escherichia coli, GI1790210, Length=288, Percent_Identity=37.8472222222222, Blast_Score=159, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6323387, Length=325, Percent_Identity=36, Blast_Score=166, Evalue=7e-42,

Paralogues:

None

Copy number: 160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013023
- InterPro:   IPR000506
- InterPro:   IPR013328
- InterPro:   IPR013116 [H]

Pfam domain/function: PF01450 IlvC; PF07991 IlvN [H]

EC number: =1.1.1.86 [H]

Molecular weight: Translated: 37666; Mature: 37535

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVYYNGDANEQYLQGKTVAIIGYGSQGHAHAQNLRDSGVHVIIGLRKGRSWEQAEQDG
CCEEEECCCCCCHHHCCCEEEEEEECCCCCHHHHHHCCCCCEEEEEECCCCCHHHHHHCC
FDVYSVREASKKADIVMVLLPDEKQPAVYKEEIEPELKPGNALVFAHGFNIHFSQIVPPE
CCEEEHHHHCCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCEEEEEECCCEEEECCCCCC
HVDVFLVAPKGPGHLVRRTYVEGAGVPALIAVYQDVTGHAKETALAYAKAIGAARAGVLE
CCEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHH
TTFKEETETDLFGEQAVLCGGLTALIKAGFETLVEAGYQPEVAYFECLHEMKLIVDLLYE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
GGLSWMRYSISDTAQWGDFTSGPRVINEAVKAEMKNILHDIQTGKFAKGWILENQANRPE
CCHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCEEECCCCCCCC
FNAINQRENEHLIEVVGRELRSMMPFVKAKQKEVVVPGAKN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCC
>Mature Secondary Structure 
AKVYYNGDANEQYLQGKTVAIIGYGSQGHAHAQNLRDSGVHVIIGLRKGRSWEQAEQDG
CEEEECCCCCCHHHCCCEEEEEEECCCCCHHHHHHCCCCCEEEEEECCCCCHHHHHHCC
FDVYSVREASKKADIVMVLLPDEKQPAVYKEEIEPELKPGNALVFAHGFNIHFSQIVPPE
CCEEEHHHHCCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCEEEEEECCCEEEECCCCCC
HVDVFLVAPKGPGHLVRRTYVEGAGVPALIAVYQDVTGHAKETALAYAKAIGAARAGVLE
CCEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHH
TTFKEETETDLFGEQAVLCGGLTALIKAGFETLVEAGYQPEVAYFECLHEMKLIVDLLYE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
GGLSWMRYSISDTAQWGDFTSGPRVINEAVKAEMKNILHDIQTGKFAKGWILENQANRPE
CCHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCEEECCCCCCCC
FNAINQRENEHLIEVVGRELRSMMPFVKAKQKEVVVPGAKN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA