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The map label for this gene is ruvA [H]

Identifier: 138896159

GI number: 138896159

Start: 2627320

End: 2627904

Strand: Reverse

Name: ruvA [H]

Synonym: GTNG_2522

Alternate gene names: 138896159

Gene position: 2627904-2627320 (Counterclockwise)

Preceding gene: 138896160

Following gene: 138896158

Centisome position: 74.02

GC content: 49.74

Gene sequence:

>585_bases
TTGATCGAGTTTATCCGCGGATATGTCGATTACATCTGTCCCGAATATATTGTGATCGACCATAACGGCATCGGCTACGA
AATTTTTACTCCCAACCCGTTTGCCTTTGAGGAGAGTCGTGAGGCAGCGGTAACGGTATATACATACGAATACGTGCGTG
AAGATGTGCACGCTTTATACGGATTTCTAACGCGTGAAGAGCGGAACTTGTTCGCCAAGCTGCTCCAAGTGTCCGGCATT
GGACCAAAAGGGGGGCTCGCTATTTTGGCAGCGGGGCGTCCGGATGAGCTGGCACGGGCGATTGAGGAAGAAAATGAAGC
ATTTTTATGTAAGTTCCCGGGTGTTGGAAAAAAAACGGCACGGCAAATGATTTTAGACTTAAAAGGAAAGCTTACGATGT
TTTCAATGCCAACGGCTCCACGACCGGCCGCTTCTCTGTCTGGGGAGCTTGCTGAGGCGATTGCTGCGCTCAAGGCGCTT
GGCTATGCGGAACGAGAAATTGAAAAAATTATTCCGGCGCTCCGCGAAGAAACGATGTCGACGGAACAGTACGTGAAGCG
GGCGTTGGCCATGTTACTGAAATAA

Upstream 100 bases:

>100_bases
AACGGAATCCCGTGGTGTGAAGCGCATCACGGGATTTGTTTTTTGCTATAATGAAATCGTATGATACAATGAAAGGACGA
GAAAAGGAGAGGAGTAGGCA

Downstream 100 bases:

>100_bases
ATGGCTGTTGGCAACGAGCCAAAAGGGAGGGACGACGGTGGACGAACGGCTTGTATCTGGATCAGCTTTAGGCGGCGAGG
CGGCGTTCGAACCAACCTTG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MIEFIRGYVDYICPEYIVIDHNGIGYEIFTPNPFAFEESREAAVTVYTYEYVREDVHALYGFLTREERNLFAKLLQVSGI
GPKGGLAILAAGRPDELARAIEEENEAFLCKFPGVGKKTARQMILDLKGKLTMFSMPTAPRPAASLSGELAEAIAALKAL
GYAEREIEKIIPALREETMSTEQYVKRALAMLLK

Sequences:

>Translated_194_residues
MIEFIRGYVDYICPEYIVIDHNGIGYEIFTPNPFAFEESREAAVTVYTYEYVREDVHALYGFLTREERNLFAKLLQVSGI
GPKGGLAILAAGRPDELARAIEEENEAFLCKFPGVGKKTARQMILDLKGKLTMFSMPTAPRPAASLSGELAEAIAALKAL
GYAEREIEKIIPALREETMSTEQYVKRALAMLLK
>Mature_194_residues
MIEFIRGYVDYICPEYIVIDHNGIGYEIFTPNPFAFEESREAAVTVYTYEYVREDVHALYGFLTREERNLFAKLLQVSGI
GPKGGLAILAAGRPDELARAIEEENEAFLCKFPGVGKKTARQMILDLKGKLTMFSMPTAPRPAASLSGELAEAIAALKAL
GYAEREIEKIIPALREETMSTEQYVKRALAMLLK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=201, Percent_Identity=34.8258706467662, Blast_Score=113, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 21673; Mature: 21673

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEFIRGYVDYICPEYIVIDHNGIGYEIFTPNPFAFEESREAAVTVYTYEYVREDVHALY
CHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHH
GFLTREERNLFAKLLQVSGIGPKGGLAILAAGRPDELARAIEEENEAFLCKFPGVGKKTA
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCEEEEECCCCCHHHH
RQMILDLKGKLTMFSMPTAPRPAASLSGELAEAIAALKALGYAEREIEKIIPALREETMS
HHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
TEQYVKRALAMLLK
HHHHHHHHHHHHCC
>Mature Secondary Structure
MIEFIRGYVDYICPEYIVIDHNGIGYEIFTPNPFAFEESREAAVTVYTYEYVREDVHALY
CHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHH
GFLTREERNLFAKLLQVSGIGPKGGLAILAAGRPDELARAIEEENEAFLCKFPGVGKKTA
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCEEEEECCCCCHHHH
RQMILDLKGKLTMFSMPTAPRPAASLSGELAEAIAALKALGYAEREIEKIIPALREETMS
HHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
TEQYVKRALAMLLK
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA