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The map label for this gene is pbpI [H]

Identifier: 138896116

GI number: 138896116

Start: 2581951

End: 2583717

Strand: Reverse

Name: pbpI [H]

Synonym: GTNG_2479

Alternate gene names: 138896116

Gene position: 2583717-2581951 (Counterclockwise)

Preceding gene: 138896117

Following gene: 138896115

Centisome position: 72.77

GC content: 53.08

Gene sequence:

>1767_bases
ATGTGGAAAAAACGGACGCTCGCCATGCTGGCGCTCATTCAATTCGGTTTGCTGCTGCTTATCGGGCGATTGGCCCAGCT
TCAGCTCATTGACACGGAATCGTTTTCCAATCATAATTTAATTGCCGAGAGCGTTGCCCAGCGCACACAAGAATTGATGA
TCGATGATGGCCGTGGGTCGTTCGTCGATCGAAATGGAAAGCCGCTTACAAAACGGTACGTGCCATCGCTTGTGTTATTT
CCGTTTTTAAACACGGTGACATGGCCAATTGAACAAGTTGCGCGCATCATAGATGTCCCTGAGGAAGAGATTCGCCGTCA
GCTCGAGCGGGCAAACGGGCCGTTCGTCTTCGAGCAAGACGGTGAGCCACTCGCGTTAAGCGAAAGGCAGATGAAACAAA
TTAACGATTTGCGCATCCCAGGTGTCTTGGCCGTCAATAAACAATATGCACTCGAGACGGTGTACGCTCCGCATGTGCTT
GGCTTCACTCGTCCGGATCGCGAGCTGTTGCGTCAACGGTATCCAAAACGACCGATCCCACCGCGGGCCGAGGCCGGTAT
TCAAGGGCTCGAGAAGGCGTTTGACGAATTTTTGCTCGCCGATGATGAGACGAAGCTGCTTTATCACGTCGATGCTGAAG
GAAGGCCGCTGTTTGGGCTCGATGTGAAATATAGCGAACCAGGTAACCCGTTTTATCCGGTGACCGTCCAAACCACACTT
GATCGTGATATACAGCAAGAGATGGAGCGGATCGTGGATCGATACGGACTGAAAAAAGGTGGTCTCGTCTTGCTAGATAT
CGATACAAACAGCGTGCTCGCTCTAGTCAGCCGCCCGAATATGGATCCGCGCGATCCGTACAAAAACCGCGGAGCGGAAA
ATCAAATGGTGCTGCCGCACATTCCCGGCTCCATCTTTAAGACAGTGATCGCCGCGGCGGCACTCGACGAAGGGCTTGCT
TCGTTCAAGACGATGTTTGACTGCAGCAAAAAAATTGACGGCATAACCCGCGATAAGGAGCACGATTACGGCATGCTCGA
CTTGACTGACAGTTTTGCTGTCAGCTGCAATAACGCCTTCGCCACCCTCGGCAAAAAGTTAATTCAGCATGATTCAGACG
CATTTGAGACGTATGCCGAAAAGCTTGGGCTGTATCCGATGGCTGGCTGGGAGGGGACGGTTTACCGTGAAGAGCAATTT
CGCCAGTTCCCGGAAGAGCGGAAAGGAACGATCTGGCACGATCGGCATGACAAGCAGGTGCCGCTCGCTGTAGCGCAAAC
GGCGATCGGGCAAAAAGATGTACGCGTCTCGCCGCTTGGCGTTGCCAATATGATGGCGACGATCGCCCGCGGTGGTGAAG
CGCTTAAAGTGCGAGCCGTCGATCAAGTACTCTATAAAAACGGTACAACGTTGTTTTCATTTTCACCCGAACCGGCGACA
AATCAGGAGCCGCTCGCGCCAAAAACGGTACAACAGCTCCAGCAGCTGTTGCGCGGTGTCGTCACTAAGGAAGAAGGAAC
CGGGCGCCGCTTCCGCTCATTGCCGTATGCTGTCGCCGGCAAATCGGGAACGGCGGAGACAGGAAAAACGGATGACGAGG
GTGAATTAATTAATAAATGGTTTGCCGGCTATTTCCCAGTTGATCGTCCGAAATATGCTCTTGTCGTCGTCGAGCTCGAC
CGCCCGAATGGGCGCACCGTGACGAACGACGTGTTTGCTGCTGCCGTCGAAACGCTTTACGCTTATGACAAAAACGAGCA
GGGATAA

Upstream 100 bases:

>100_bases
GCCAAACGGACAGCGGTGTAAACAAAGCGGGAAAATCACTGCCTTTGGTACGTTTCAAACGAAAACACCTCGTCAAAACT
GATGATGAGGTGTTTTCTTT

Downstream 100 bases:

>100_bases
CGAACTCGTATAGAGAACCCGTTTTTCAGCAGGAAAACCGCATAAAAAAGGGGGAGGAGACTATGCCACAAACAGGGACG
CGCTTTGCCGCCCGCGCTAA

Product: penicillin-binding protein-like protein

Products: NA

Alternate protein names: PBP-4B; PBP4b; Penicillin-binding protein I [H]

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MWKKRTLAMLALIQFGLLLLIGRLAQLQLIDTESFSNHNLIAESVAQRTQELMIDDGRGSFVDRNGKPLTKRYVPSLVLF
PFLNTVTWPIEQVARIIDVPEEEIRRQLERANGPFVFEQDGEPLALSERQMKQINDLRIPGVLAVNKQYALETVYAPHVL
GFTRPDRELLRQRYPKRPIPPRAEAGIQGLEKAFDEFLLADDETKLLYHVDAEGRPLFGLDVKYSEPGNPFYPVTVQTTL
DRDIQQEMERIVDRYGLKKGGLVLLDIDTNSVLALVSRPNMDPRDPYKNRGAENQMVLPHIPGSIFKTVIAAAALDEGLA
SFKTMFDCSKKIDGITRDKEHDYGMLDLTDSFAVSCNNAFATLGKKLIQHDSDAFETYAEKLGLYPMAGWEGTVYREEQF
RQFPEERKGTIWHDRHDKQVPLAVAQTAIGQKDVRVSPLGVANMMATIARGGEALKVRAVDQVLYKNGTTLFSFSPEPAT
NQEPLAPKTVQQLQQLLRGVVTKEEGTGRRFRSLPYAVAGKSGTAETGKTDDEGELINKWFAGYFPVDRPKYALVVVELD
RPNGRTVTNDVFAAAVETLYAYDKNEQG

Sequences:

>Translated_588_residues
MWKKRTLAMLALIQFGLLLLIGRLAQLQLIDTESFSNHNLIAESVAQRTQELMIDDGRGSFVDRNGKPLTKRYVPSLVLF
PFLNTVTWPIEQVARIIDVPEEEIRRQLERANGPFVFEQDGEPLALSERQMKQINDLRIPGVLAVNKQYALETVYAPHVL
GFTRPDRELLRQRYPKRPIPPRAEAGIQGLEKAFDEFLLADDETKLLYHVDAEGRPLFGLDVKYSEPGNPFYPVTVQTTL
DRDIQQEMERIVDRYGLKKGGLVLLDIDTNSVLALVSRPNMDPRDPYKNRGAENQMVLPHIPGSIFKTVIAAAALDEGLA
SFKTMFDCSKKIDGITRDKEHDYGMLDLTDSFAVSCNNAFATLGKKLIQHDSDAFETYAEKLGLYPMAGWEGTVYREEQF
RQFPEERKGTIWHDRHDKQVPLAVAQTAIGQKDVRVSPLGVANMMATIARGGEALKVRAVDQVLYKNGTTLFSFSPEPAT
NQEPLAPKTVQQLQQLLRGVVTKEEGTGRRFRSLPYAVAGKSGTAETGKTDDEGELINKWFAGYFPVDRPKYALVVVELD
RPNGRTVTNDVFAAAVETLYAYDKNEQG
>Mature_588_residues
MWKKRTLAMLALIQFGLLLLIGRLAQLQLIDTESFSNHNLIAESVAQRTQELMIDDGRGSFVDRNGKPLTKRYVPSLVLF
PFLNTVTWPIEQVARIIDVPEEEIRRQLERANGPFVFEQDGEPLALSERQMKQINDLRIPGVLAVNKQYALETVYAPHVL
GFTRPDRELLRQRYPKRPIPPRAEAGIQGLEKAFDEFLLADDETKLLYHVDAEGRPLFGLDVKYSEPGNPFYPVTVQTTL
DRDIQQEMERIVDRYGLKKGGLVLLDIDTNSVLALVSRPNMDPRDPYKNRGAENQMVLPHIPGSIFKTVIAAAALDEGLA
SFKTMFDCSKKIDGITRDKEHDYGMLDLTDSFAVSCNNAFATLGKKLIQHDSDAFETYAEKLGLYPMAGWEGTVYREEQF
RQFPEERKGTIWHDRHDKQVPLAVAQTAIGQKDVRVSPLGVANMMATIARGGEALKVRAVDQVLYKNGTTLFSFSPEPAT
NQEPLAPKTVQQLQQLLRGVVTKEEGTGRRFRSLPYAVAGKSGTAETGKTDDEGELINKWFAGYFPVDRPKYALVVVELD
RPNGRTVTNDVFAAAVETLYAYDKNEQG

Specific function: Penicillin-binding protein with an unknown catalytic activity. Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Beta-lactamase inactivates the PBPs by acylating an essential serine residue in the active site of these p

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 66091; Mature: 66091

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWKKRTLAMLALIQFGLLLLIGRLAQLQLIDTESFSNHNLIAESVAQRTQELMIDDGRGS
CCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHEEECCCCC
FVDRNGKPLTKRYVPSLVLFPFLNTVTWPIEQVARIIDVPEEEIRRQLERANGPFVFEQD
EECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHCCCCEEECCC
GEPLALSERQMKQINDLRIPGVLAVNKQYALETVYAPHVLGFTRPDRELLRQRYPKRPIP
CCCCCCCHHHHHHHHHCCCCCEEEECCHHHHHHHHCCHHCCCCCCHHHHHHHHCCCCCCC
PRAEAGIQGLEKAFDEFLLADDETKLLYHVDAEGRPLFGLDVKYSEPGNPFYPVTVQTTL
CCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEEEECCCCCCEEEEEEEHHH
DRDIQQEMERIVDRYGLKKGGLVLLDIDTNSVLALVSRPNMDPRDPYKNRGAENQMVLPH
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCCCHHCCCCCCCEEECC
IPGSIFKTVIAAAALDEGLASFKTMFDCSKKIDGITRDKEHDYGMLDLTDSFAVSCNNAF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEECCHHH
ATLGKKLIQHDSDAFETYAEKLGLYPMAGWEGTVYREEQFRQFPEERKGTIWHDRHDKQV
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEHHHHHCCHHHHCCCCCCCCCCCCC
PLAVAQTAIGQKDVRVSPLGVANMMATIARGGEALKVRAVDQVLYKNGTTLFSFSPEPAT
CHHHHHHHCCCCCCEECCCHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCEEEEECCCCCC
NQEPLAPKTVQQLQQLLRGVVTKEEGTGRRFRSLPYAVAGKSGTAETGKTDDEGELINKW
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCEEECCCCCCCCCCCCCHHHHHHHH
FAGYFPVDRPKYALVVVELDRPNGRTVTNDVFAAAVETLYAYDKNEQG
HHCCCCCCCCCEEEEEEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MWKKRTLAMLALIQFGLLLLIGRLAQLQLIDTESFSNHNLIAESVAQRTQELMIDDGRGS
CCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHEEECCCCC
FVDRNGKPLTKRYVPSLVLFPFLNTVTWPIEQVARIIDVPEEEIRRQLERANGPFVFEQD
EECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHCCCCEEECCC
GEPLALSERQMKQINDLRIPGVLAVNKQYALETVYAPHVLGFTRPDRELLRQRYPKRPIP
CCCCCCCHHHHHHHHHCCCCCEEEECCHHHHHHHHCCHHCCCCCCHHHHHHHHCCCCCCC
PRAEAGIQGLEKAFDEFLLADDETKLLYHVDAEGRPLFGLDVKYSEPGNPFYPVTVQTTL
CCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEEEECCCCCCEEEEEEEHHH
DRDIQQEMERIVDRYGLKKGGLVLLDIDTNSVLALVSRPNMDPRDPYKNRGAENQMVLPH
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCCCHHCCCCCCCEEECC
IPGSIFKTVIAAAALDEGLASFKTMFDCSKKIDGITRDKEHDYGMLDLTDSFAVSCNNAF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEECCHHH
ATLGKKLIQHDSDAFETYAEKLGLYPMAGWEGTVYREEQFRQFPEERKGTIWHDRHDKQV
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEHHHHHCCHHHHCCCCCCCCCCCCC
PLAVAQTAIGQKDVRVSPLGVANMMATIARGGEALKVRAVDQVLYKNGTTLFSFSPEPAT
CHHHHHHHCCCCCCEECCCHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCEEEEECCCCCC
NQEPLAPKTVQQLQQLLRGVVTKEEGTGRRFRSLPYAVAGKSGTAETGKTDDEGELINKW
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCEEECCCCCCCCCCCCCHHHHHHHH
FAGYFPVDRPKYALVVVELDRPNGRTVTNDVFAAAVETLYAYDKNEQG
HHCCCCCCCCCEEEEEEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]