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The map label for this gene is era [H]

Identifier: 138896062

GI number: 138896062

Start: 2533250

End: 2534158

Strand: Reverse

Name: era [H]

Synonym: GTNG_2425

Alternate gene names: 138896062

Gene position: 2534158-2533250 (Counterclockwise)

Preceding gene: 138896063

Following gene: 138896061

Centisome position: 71.38

GC content: 48.95

Gene sequence:

>909_bases
ATGAATAAACAGGGATACAAATCAGGATTTGTTGCTATTATCGGAAGACCAAACGTAGGAAAATCAACGTTTTTAAACCG
CGTCATTGGGCAAAAAATCGCCATTATGAGCGACAAGCCACAAACGACGCGTAATAAAATTCAAGGTGTTTATACGGACG
ATGAAGCCCAAATCATTTTCATCGACACCCCAGGGGTTCATAAACCGAAACACAAGCTCGGCGACTTTATGATGAAAGTG
GCGCTCAATGCGCTTCGCGAAGTCGATTTGATTTTGTTTATGGTCAATGCGGAGGAAGGATTTGGGCGCGGCGAAGCGTT
TATTATTGAGCGGTTGAACGAAGTCAATACTCCGGTGTTTTTAGTGATCAATAAAATCGACCGCGTCCATCCGGATGAAC
TGCTGCCGATCATTGACCGGTACAAGGATTTGTACACTTTTGCCGAGATCGTGCCAATTTCGGCGCTTGAAGGGAACAAT
GTCGAGCGTCTGTTGGAGCAAATTAAACAACGATTGCCAGAAGGGCCGCAATATTACCCACCGGATCAGATTACCGACCA
TCCGGAACAGTTTATTATTGCCGAGCTCATTCGTGAGAAAGCGCTTCACTTAACGCGCGAGGAAGTTCCGCATTCGATCG
CTGTCGTCGTGGAACGCATCGAGCGGCGCGAGGAGACGGGCACAGTATACGTCGGCGCTGTCATCGTTGTCGAGCGTGAT
TCACAAAAAGGGATCATCATCGGCAAACAAGGCCGAATGCTAAAGGAAATCGGGCAGCGGGCGCGCGCTGACATTGAGGC
GCTGCTCGGGTCAAGAGTGTTTTTGGAGCTGTGGGTGAAGGTGCAAAAAGATTGGCGCAACCGTCTTGTGCAGCTGCGTG
ACTTCGGGTTTCGAGAAGACGAGTATTGA

Upstream 100 bases:

>100_bases
CCCGGCGATATGAAGGTCATTTTGGCCAACTTAAGCGGAGATATCAAAATAGTCACTGTTAACGAATTACTGCCAGAAGC
TTTTGCAGCGGAGGATATGC

Downstream 100 bases:

>100_bases
AGGCTAGAAAATTTTACGCGACATAAACCATTTTTGCCCGAGCCAACCTATAGGTAGACCACCAATACGCAATGCCTGCA
GGCGGAAAGAGGTGTCATTC

Product: GTP-binding protein

Products: NA

Alternate protein names: Bex protein [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MNKQGYKSGFVAIIGRPNVGKSTFLNRVIGQKIAIMSDKPQTTRNKIQGVYTDDEAQIIFIDTPGVHKPKHKLGDFMMKV
ALNALREVDLILFMVNAEEGFGRGEAFIIERLNEVNTPVFLVINKIDRVHPDELLPIIDRYKDLYTFAEIVPISALEGNN
VERLLEQIKQRLPEGPQYYPPDQITDHPEQFIIAELIREKALHLTREEVPHSIAVVVERIERREETGTVYVGAVIVVERD
SQKGIIIGKQGRMLKEIGQRARADIEALLGSRVFLELWVKVQKDWRNRLVQLRDFGFREDEY

Sequences:

>Translated_302_residues
MNKQGYKSGFVAIIGRPNVGKSTFLNRVIGQKIAIMSDKPQTTRNKIQGVYTDDEAQIIFIDTPGVHKPKHKLGDFMMKV
ALNALREVDLILFMVNAEEGFGRGEAFIIERLNEVNTPVFLVINKIDRVHPDELLPIIDRYKDLYTFAEIVPISALEGNN
VERLLEQIKQRLPEGPQYYPPDQITDHPEQFIIAELIREKALHLTREEVPHSIAVVVERIERREETGTVYVGAVIVVERD
SQKGIIIGKQGRMLKEIGQRARADIEALLGSRVFLELWVKVQKDWRNRLVQLRDFGFREDEY
>Mature_302_residues
MNKQGYKSGFVAIIGRPNVGKSTFLNRVIGQKIAIMSDKPQTTRNKIQGVYTDDEAQIIFIDTPGVHKPKHKLGDFMMKV
ALNALREVDLILFMVNAEEGFGRGEAFIIERLNEVNTPVFLVINKIDRVHPDELLPIIDRYKDLYTFAEIVPISALEGNN
VERLLEQIKQRLPEGPQYYPPDQITDHPEQFIIAELIREKALHLTREEVPHSIAVVVERIERREETGTVYVGAVIVVERD
SQKGIIIGKQGRMLKEIGQRARADIEALLGSRVFLELWVKVQKDWRNRLVQLRDFGFREDEY

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. Binds both GDP and GTP. Complements

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=326, Percent_Identity=26.0736196319018, Blast_Score=86, Evalue=5e-17,
Organism=Escherichia coli, GI1788919, Length=295, Percent_Identity=39.3220338983051, Blast_Score=221, Evalue=4e-59,
Organism=Escherichia coli, GI87082120, Length=181, Percent_Identity=34.2541436464088, Blast_Score=97, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24646434, Length=307, Percent_Identity=25.7328990228013, Blast_Score=105, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34697; Mature: 34697

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQGYKSGFVAIIGRPNVGKSTFLNRVIGQKIAIMSDKPQTTRNKIQGVYTDDEAQIIF
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEECCCCCHHHHHCCCEEECCCCEEEE
IDTPGVHKPKHKLGDFMMKVALNALREVDLILFMVNAEEGFGRGEAFIIERLNEVNTPVF
EECCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCHHHHHHHHHHCCCCEE
LVINKIDRVHPDELLPIIDRYKDLYTFAEIVPISALEGNNVERLLEQIKQRLPEGPQYYP
EEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCC
PDQITDHPEQFIIAELIREKALHLTREEVPHSIAVVVERIERREETGTVYVGAVIVVERD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEEEEEEEEC
SQKGIIIGKQGRMLKEIGQRARADIEALLGSRVFLELWVKVQKDWRNRLVQLRDFGFRED
CCCCEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EY
CC
>Mature Secondary Structure
MNKQGYKSGFVAIIGRPNVGKSTFLNRVIGQKIAIMSDKPQTTRNKIQGVYTDDEAQIIF
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEECCCCCHHHHHCCCEEECCCCEEEE
IDTPGVHKPKHKLGDFMMKVALNALREVDLILFMVNAEEGFGRGEAFIIERLNEVNTPVF
EECCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCHHHHHHHHHHCCCCEE
LVINKIDRVHPDELLPIIDRYKDLYTFAEIVPISALEGNNVERLLEQIKQRLPEGPQYYP
EEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCC
PDQITDHPEQFIIAELIREKALHLTREEVPHSIAVVVERIERREETGTVYVGAVIVVERD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEEEEEEEEC
SQKGIIIGKQGRMLKEIGQRARADIEALLGSRVFLELWVKVQKDWRNRLVQLRDFGFRED
CCCCEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EY
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 2526291 [H]