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The map label for this gene is cdd [H]

Identifier: 138896063

GI number: 138896063

Start: 2534151

End: 2534549

Strand: Reverse

Name: cdd [H]

Synonym: GTNG_2426

Alternate gene names: 138896063

Gene position: 2534549-2534151 (Counterclockwise)

Preceding gene: 138896064

Following gene: 138896062

Centisome position: 71.39

GC content: 51.63

Gene sequence:

>399_bases
GTGAAAATCGAGCAGCTCATTGTCGAAGCGAAAAAAGCGCGCGAACTCGCCTACGTGCCGTACTCAAAGTTTAAAGTTGG
CGCCGCTTTATTGACGAAAGGCGGCAGCGTATATCGTGGTTGCAACATTGAGAATGCTGCCTACAGCATGTGTAATTGTG
CGGAACGAACCGCGCTGTTTAAGGCATATTCGGAAGGGGAGACGGAGTTTGCTGCGCTTGCGGTCATCGCTGACACCCCT
CGTCCGGTGCCGCCGTGCGGCGCATGCCGCCAAGTGATCGCCGAACTTTGTCCCGGCGATATGAAGGTCATTTTGGCCAA
CTTAAGCGGAGATATCAAAATAGTCACTGTTAACGAATTACTGCCAGAAGCTTTTGCAGCGGAGGATATGCATGAATAA

Upstream 100 bases:

>100_bases
ATTTTTCTGTTACATTTTCGTTTCAGATGATGAAATTTACGCTGTTTTTTTGTAAAATAAAAGAAAGCAGTGGTTGCTTT
CAGGAAGGGAAGAGTTATTG

Downstream 100 bases:

>100_bases
ACAGGGATACAAATCAGGATTTGTTGCTATTATCGGAAGACCAAACGTAGGAAAATCAACGTTTTTAAACCGCGTCATTG
GGCAAAAAATCGCCATTATG

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MKIEQLIVEAKKARELAYVPYSKFKVGAALLTKGGSVYRGCNIENAAYSMCNCAERTALFKAYSEGETEFAALAVIADTP
RPVPPCGACRQVIAELCPGDMKVILANLSGDIKIVTVNELLPEAFAAEDMHE

Sequences:

>Translated_132_residues
MKIEQLIVEAKKARELAYVPYSKFKVGAALLTKGGSVYRGCNIENAAYSMCNCAERTALFKAYSEGETEFAALAVIADTP
RPVPPCGACRQVIAELCPGDMKVILANLSGDIKIVTVNELLPEAFAAEDMHE
>Mature_132_residues
MKIEQLIVEAKKARELAYVPYSKFKVGAALLTKGGSVYRGCNIENAAYSMCNCAERTALFKAYSEGETEFAALAVIADTP
RPVPPCGACRQVIAELCPGDMKVILANLSGDIKIVTVNELLPEAFAAEDMHE

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=131, Percent_Identity=46.5648854961832, Blast_Score=120, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17540514, Length=127, Percent_Identity=45.6692913385827, Blast_Score=112, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17551074, Length=132, Percent_Identity=44.6969696969697, Blast_Score=98, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323274, Length=133, Percent_Identity=38.3458646616541, Blast_Score=98, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24582741, Length=130, Percent_Identity=46.9230769230769, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI19920920, Length=121, Percent_Identity=47.9338842975207, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24582744, Length=136, Percent_Identity=41.9117647058824, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14244; Mature: 14244

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEQLIVEAKKARELAYVPYSKFKVGAALLTKGGSVYRGCNIENAAYSMCNCAERTALF
CCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHH
KAYSEGETEFAALAVIADTPRPVPPCGACRQVIAELCPGDMKVILANLSGDIKIVTVNEL
HHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEHHHH
LPEAFAAEDMHE
HHHHHHHCCCCC
>Mature Secondary Structure
MKIEQLIVEAKKARELAYVPYSKFKVGAALLTKGGSVYRGCNIENAAYSMCNCAERTALF
CCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHH
KAYSEGETEFAALAVIADTPRPVPPCGACRQVIAELCPGDMKVILANLSGDIKIVTVNEL
HHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEHHHH
LPEAFAAEDMHE
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2526291; 8969508; 9384377 [H]