Click here to switch to the map view.

The map label for this gene is metA [H]

Identifier: 138895336

GI number: 138895336

Start: 1769588

End: 1770430

Strand: Direct

Name: metA [H]

Synonym: GTNG_1680

Alternate gene names: 138895336

Gene position: 1769588-1770430 (Clockwise)

Preceding gene: 138895319

Following gene: 138895357

Centisome position: 49.84

GC content: 48.87

Gene sequence:

>843_bases
ATGGACGAAGAACGGGCTTACTCCCAAGACATCCGGCCGCTCAACATCATCATTTTAAACTTGATGCCCGAAAAAGAAAA
AGCAGAGACACAGTTGCTGCGGCTGCTTGGCAACTCGCCGCTGCAAGTGAACGTCACCTTTTTGCGTCCGGCGACCCATG
AACCGAAAACGACGAGTAAACATCATTTGGATCAATTTTACACAATTTTTCCTCACATCCGCCATCGGAAGTTCGACGGA
ATGATCATCACAGGAGCGCCGGTCGAGCAAATGCCGTTTGAAGAAGTGACGTACTGGGACGAGTTGACCGACATTATGGA
ATGGACAAAAACAAACGTCACATCGACGCTCCATATTTGCTGGGGGGCGCAAGCCGGCTTGTATTACCATTATGGCATTC
CGAAATATCCACTGCCGAAAAAATGCTTCGGCGTGTTCAACCATACACTGGAAGTAAAAAATGTAAAGCTTTTGCGCGGC
TTTGACGACGTGTTCCGCATGCCGCACTCCCGCCATACGGACGTCAAGCGAGAAGACATTGAAAAAGTGCCGGAGCTCAT
GATTTTATCAGTCGCCGACAAAGCTGGCGTTTGCCTTGTCGCCTCGAACGACGGCCGTCATATTTTCTTGACCGGTCATC
CAGAATATGATGCAACAACGTTAAAAGACGAATATGAGCGCGATTTGGCCAAAGGGTTACCGATTCAACTTCCGGAGTCG
TACTTCCCGAATGATGACCCGAGTCAACCGCCGCTCAATACGTGGCGCTCACACGCCAATTTGCTGTTTGTCAACTGGCT
CAACTATTACGTCTATCAGGAAACGCCTTATATTTGGGAATAA

Upstream 100 bases:

>100_bases
ATTTAGTAACGAGACAGAAACGGAGGGGACACCATTGCCAATCAACATTCCAAAAGACTTGCCGGCGAAAGAAATACTCG
AACAGGAAAACATTTTCGTG

Downstream 100 bases:

>100_bases
AAAGAAGTCCCATCCAACAACAAAAACGCCTTTGCTTTCCTAGCAAGGCGTTTTTGTTATTTTGCATTTTTCGACAATTT
TCCCGTGCATTCATGCAATA

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MDEERAYSQDIRPLNIIILNLMPEKEKAETQLLRLLGNSPLQVNVTFLRPATHEPKTTSKHHLDQFYTIFPHIRHRKFDG
MIITGAPVEQMPFEEVTYWDELTDIMEWTKTNVTSTLHICWGAQAGLYYHYGIPKYPLPKKCFGVFNHTLEVKNVKLLRG
FDDVFRMPHSRHTDVKREDIEKVPELMILSVADKAGVCLVASNDGRHIFLTGHPEYDATTLKDEYERDLAKGLPIQLPES
YFPNDDPSQPPLNTWRSHANLLFVNWLNYYVYQETPYIWE

Sequences:

>Translated_280_residues
MDEERAYSQDIRPLNIIILNLMPEKEKAETQLLRLLGNSPLQVNVTFLRPATHEPKTTSKHHLDQFYTIFPHIRHRKFDG
MIITGAPVEQMPFEEVTYWDELTDIMEWTKTNVTSTLHICWGAQAGLYYHYGIPKYPLPKKCFGVFNHTLEVKNVKLLRG
FDDVFRMPHSRHTDVKREDIEKVPELMILSVADKAGVCLVASNDGRHIFLTGHPEYDATTLKDEYERDLAKGLPIQLPES
YFPNDDPSQPPLNTWRSHANLLFVNWLNYYVYQETPYIWE
>Mature_280_residues
MDEERAYSQDIRPLNIIILNLMPEKEKAETQLLRLLGNSPLQVNVTFLRPATHEPKTTSKHHLDQFYTIFPHIRHRKFDG
MIITGAPVEQMPFEEVTYWDELTDIMEWTKTNVTSTLHICWGAQAGLYYHYGIPKYPLPKKCFGVFNHTLEVKNVKLLRG
FDDVFRMPHSRHTDVKREDIEKVPELMILSVADKAGVCLVASNDGRHIFLTGHPEYDATTLKDEYERDLAKGLPIQLPES
YFPNDDPSQPPLNTWRSHANLLFVNWLNYYVYQETPYIWE

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family [H]

Homologues:

Organism=Escherichia coli, GI1790443, Length=277, Percent_Identity=48.7364620938628, Blast_Score=276, Evalue=9e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005697
- ProDom:   PD037892 [H]

Pfam domain/function: PF04204 HTS [H]

EC number: =2.3.1.46 [H]

Molecular weight: Translated: 32731; Mature: 32731

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEERAYSQDIRPLNIIILNLMPEKEKAETQLLRLLGNSPLQVNVTFLRPATHEPKTTSK
CCCHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCH
HHLDQFYTIFPHIRHRKFDGMIITGAPVEQMPFEEVTYWDELTDIMEWTKTNVTSTLHIC
HHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEE
WGAQAGLYYHYGIPKYPLPKKCFGVFNHTLEVKNVKLLRGFDDVFRMPHSRHTDVKREDI
ECCCCCEEEECCCCCCCCCHHHHHHHHCEEEECCEEEECCCHHHHCCCCCCCCCCCHHHH
EKVPELMILSVADKAGVCLVASNDGRHIFLTGHPEYDATTLKDEYERDLAKGLPIQLPES
HHHHHEEEEEECCCCCEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCC
YFPNDDPSQPPLNTWRSHANLLFVNWLNYYVYQETPYIWE
CCCCCCCCCCCHHHHHCCCCEEEEEEEEEEEEECCCCCCC
>Mature Secondary Structure
MDEERAYSQDIRPLNIIILNLMPEKEKAETQLLRLLGNSPLQVNVTFLRPATHEPKTTSK
CCCHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCH
HHLDQFYTIFPHIRHRKFDGMIITGAPVEQMPFEEVTYWDELTDIMEWTKTNVTSTLHIC
HHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEE
WGAQAGLYYHYGIPKYPLPKKCFGVFNHTLEVKNVKLLRGFDDVFRMPHSRHTDVKREDI
ECCCCCEEEECCCCCCCCCHHHHHHHHCEEEECCEEEECCCHHHHCCCCCCCCCCCHHHH
EKVPELMILSVADKAGVCLVASNDGRHIFLTGHPEYDATTLKDEYERDLAKGLPIQLPES
HHHHHEEEEEECCCCCEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCC
YFPNDDPSQPPLNTWRSHANLLFVNWLNYYVYQETPYIWE
CCCCCCCCCCCHHHHHCCCCEEEEEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA