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The map label for this gene is bsaA [H]

Identifier: 138895334

GI number: 138895334

Start: 1768350

End: 1768718

Strand: Reverse

Name: bsaA [H]

Synonym: GTNG_1678

Alternate gene names: 138895334

Gene position: 1768718-1768350 (Counterclockwise)

Preceding gene: 138895335

Following gene: 138895333

Centisome position: 49.82

GC content: 47.43

Gene sequence:

>369_bases
TTGACACCGCAATATCAAGAATTGCAGGAGTTGTATGACGAATATCGTGACCGCGGGTTTGTCGTGCTGGGGTTTCCGTG
CAATCAATTCGGTGGCCAAGAACCGGGAACGGAAGAGGAAATCGAGCAGTTTTGCCAGTTGAATTACGGTGTAACGTTTC
CGATGTTTGCAAAGGTGGATGTTAATGGCGACAACGCCCATCCACTGTTTCAATACTTGAAAGAACAAGCACCAGGGGCA
CTTGGCACGAAGGCGATCAAATGGAATTTTACTAAGTTTTTGGTTGACCGCGATGGTCGAGTTGTTGCCCGCTTCGCTCC
GCAAACGAAGCCGAGCGAGTTGAAAAAGGAAATTGAAAAATTGTTGTAG

Upstream 100 bases:

>100_bases
ATACGAGTTCAGCGCTAAGACGATTCGCGGGGAAGAGCAGTCGCTGTCTGCCTATCGCGGGGACGTTCTTCTTATTGTCA
ACACGGCCAGCCGATGCGGT

Downstream 100 bases:

>100_bases
TCTTTTTGTGAAGGAGGGATGACGGTTGCGCATTAAAGCGATTGAGCCGACACCAAGTCCGAACACGATGAAAATATTAC
TTGATGAAGAACTGCCTTCC

Product: glutathione peroxidase

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MTPQYQELQELYDEYRDRGFVVLGFPCNQFGGQEPGTEEEIEQFCQLNYGVTFPMFAKVDVNGDNAHPLFQYLKEQAPGA
LGTKAIKWNFTKFLVDRDGRVVARFAPQTKPSELKKEIEKLL

Sequences:

>Translated_122_residues
MTPQYQELQELYDEYRDRGFVVLGFPCNQFGGQEPGTEEEIEQFCQLNYGVTFPMFAKVDVNGDNAHPLFQYLKEQAPGA
LGTKAIKWNFTKFLVDRDGRVVARFAPQTKPSELKKEIEKLL
>Mature_121_residues
TPQYQELQELYDEYRDRGFVVLGFPCNQFGGQEPGTEEEIEQFCQLNYGVTFPMFAKVDVNGDNAHPLFQYLKEQAPGAL
GTKAIKWNFTKFLVDRDGRVVARFAPQTKPSELKKEIEKLL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=117, Percent_Identity=49.5726495726496, Blast_Score=120, Evalue=3e-28,
Organism=Homo sapiens, GI90903240, Length=117, Percent_Identity=49.5726495726496, Blast_Score=119, Evalue=6e-28,
Organism=Homo sapiens, GI15618997, Length=119, Percent_Identity=42.8571428571429, Blast_Score=103, Evalue=5e-23,
Organism=Homo sapiens, GI90903238, Length=92, Percent_Identity=53.2608695652174, Blast_Score=99, Evalue=1e-21,
Organism=Homo sapiens, GI192455698, Length=119, Percent_Identity=38.655462184874, Blast_Score=93, Evalue=6e-20,
Organism=Homo sapiens, GI4557629, Length=137, Percent_Identity=40.1459854014599, Blast_Score=86, Evalue=7e-18,
Organism=Homo sapiens, GI33186887, Length=143, Percent_Identity=37.7622377622378, Blast_Score=82, Evalue=9e-17,
Organism=Homo sapiens, GI41406084, Length=141, Percent_Identity=36.8794326241135, Blast_Score=81, Evalue=2e-16,
Organism=Homo sapiens, GI6006001, Length=137, Percent_Identity=38.6861313868613, Blast_Score=80, Evalue=4e-16,
Organism=Homo sapiens, GI32967607, Length=144, Percent_Identity=32.6388888888889, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788003, Length=132, Percent_Identity=46.2121212121212, Blast_Score=131, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17535473, Length=119, Percent_Identity=51.2605042016807, Blast_Score=127, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17506887, Length=119, Percent_Identity=47.8991596638655, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71993584, Length=120, Percent_Identity=44.1666666666667, Blast_Score=112, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI193210707, Length=125, Percent_Identity=47.2, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17550320, Length=127, Percent_Identity=33.8582677165354, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI193209493, Length=127, Percent_Identity=33.0708661417323, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17507603, Length=105, Percent_Identity=35.2380952380952, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319721, Length=121, Percent_Identity=65.2892561983471, Blast_Score=178, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6322228, Length=121, Percent_Identity=61.1570247933884, Blast_Score=169, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6322826, Length=121, Percent_Identity=51.2396694214876, Blast_Score=136, Evalue=9e-34,
Organism=Drosophila melanogaster, GI24656772, Length=121, Percent_Identity=50.4132231404959, Blast_Score=122, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24656767, Length=121, Percent_Identity=50.4132231404959, Blast_Score=122, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24656777, Length=121, Percent_Identity=50.4132231404959, Blast_Score=122, Evalue=6e-29,
Organism=Drosophila melanogaster, GI85726443, Length=121, Percent_Identity=39.6694214876033, Blast_Score=89, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: NA

Molecular weight: Translated: 14040; Mature: 13909

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPQYQELQELYDEYRDRGFVVLGFPCNQFGGQEPGTEEEIEQFCQLNYGVTFPMFAKVD
CCCCHHHHHHHHHHHHCCCEEEECCCHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEE
VNGDNAHPLFQYLKEQAPGALGTKAIKWNFTKFLVDRDGRVVARFAPQTKPSELKKEIEK
CCCCCCCHHHHHHHHHCCCCCCCCEEEECHHHEEECCCCCEEEEECCCCCHHHHHHHHHH
LL
HC
>Mature Secondary Structure 
TPQYQELQELYDEYRDRGFVVLGFPCNQFGGQEPGTEEEIEQFCQLNYGVTFPMFAKVD
CCCHHHHHHHHHHHHCCCEEEECCCHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEE
VNGDNAHPLFQYLKEQAPGALGTKAIKWNFTKFLVDRDGRVVARFAPQTKPSELKKEIEK
CCCCCCCHHHHHHHHHCCCCCCCCEEEECHHHEEECCCCCEEEEECCCCCHHHHHHHHHH
LL
HC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]