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The map label for this gene is treP [H]

Identifier: 138895300

GI number: 138895300

Start: 1732277

End: 1733692

Strand: Reverse

Name: treP [H]

Synonym: GTNG_1644

Alternate gene names: 138895300

Gene position: 1733692-1732277 (Counterclockwise)

Preceding gene: 138895302

Following gene: 138895299

Centisome position: 48.83

GC content: 51.48

Gene sequence:

>1416_bases
ATGGGGGCATATGCACAAGCAGCTGCACAAATCGTTGAGGCCATCGGCGGCAAAGAGAACATCGTCGCCGCCACACATTG
TGTGACACGGCTCCGGTTTGCGCTCAAAGACGAAGGAAAAGTGGATAAAGAAGCGCTTGAACGCATTGATGTAGTGAAAG
GGTCGTTTTCGGCAAACGGCCAGTTTCAAGTTGTCATCGGTCAAGGGCTCGTTGATAAAGTGTATAACGAACTCGTTGAG
TTGACTGGCATTGGCCGGGCGACGAAACAGGAAATTAAAGATGCGGCGGAAGCGAAGCTCAATCCGCTGCAACGCGCCAT
TAAGACGCTCGCTGACATTTTTATCCCGATTTTGCCGGCGATCGTCACAGCTGGTCTGTTAATGGGAATTAATAACGTTT
TGACCGGTCCAGACATTTTTTATGAGGGGAAATCGTTTGTCGATGTGCATCAAGAATGGGCAGATTTGGCGAATATGATC
AACTTGATCGCCAATACGGCGTTTGTCTTCCTGCCGGGGTTGATCGGTTGGTCGGCGGTGACAAAATTCGGAGGCAGTCC
GCTGTTGGGGATTGTTCTTGGCTTGATGCTCGTCCACCCGGATTTGCTGAATGCTTGGGGCTGGGGAGCAGCAAAACAAG
AAGGAGAAATCCCAGTTTGGAACTTATTCGGGTTTGATGTGCAAAAAGTCGGCTATCAAGGGCAAGTGCTGCCTGTGTTA
GTTGCTTCGTACGTATTGGCGAAGATCGAGCTGTTTTTGCGCAACCGCATTCCGGATGCGTTTCAACTGTTGCTTGTCGC
ACCGCTTGCCTTGCTCGTGACAGGTTTCTTGGCGTTTATCGCCATCGGACCGATCACGTTCGCGATCGGGAACGCGATTA
CGAACTTGTTTGTCGGAATTTTTGACAACGTTCCAGCCATTGGTGGTTTGCTGTATGGAGCGCTGTATGCGCCGCTTGTC
GTTACCGGGATGCACCATACATTCTTGCCGGTTGATTTGCAGCTGATTGCTAGCACGGGCGGCACGTTCTTATGGCCGAT
TTTAGTCATGTCGAATATCGCCCAAGGTTCTGCGGCATTAGCGATGATGTTTGTCGCAAAAGACGAAAAGCTGCGCGGAT
TGTCGTTCACTTCAGCGGTTTCGGCCTATCTCGGCATTACCGAGCCGGCGATGTTCGGGGTCAACTTGCGCTTCCGATTC
CCGTTTATTGCAGCGATGACAGGGGCAGCGATTGCCGGCATGTTTATCACACTCAATAAAGTCCTTGCTCCATCGATCGG
CGTCGGCGGTCTGCCGGGCTTCTTGTCGATCGTGCCACAGAAATGGGTCCCGTTCTTTATCGGGATGGCGATTGCCATTG
TAGTGCCGTTTGTGCTGACATTTGTTTTCGGCAAAGTGCGCAAAGTGGCACGCTAA

Upstream 100 bases:

>100_bases
AGAATGAGTTCAGGATGTATATACAAGTTTTTTTGCAACCGGTTGCTGAAAGCGATTTAACGCAATTGAAAGCGAGAGAA
AGAAAAAGGAGGCATTCATA

Downstream 100 bases:

>100_bases
TGGTTCACATTTATTGAGGTAATGATGCATTCGCTGACATACCATTGGCTGCCAACGCCAATGGTATGTTTTTCATTCAT
TGTCGAAGTCAACAAACGAG

Product: PTS system trehalose-specific transporter subunit IIBC

Products: NA

Alternate protein names: EIIBC-Tre; EII-Tre; Trehalose-specific phosphotransferase enzyme IIB component; PTS system trehalose-specific EIIB component; Trehalose permease IIC component; PTS system trehalose-specific EIIC component [H]

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MGAYAQAAAQIVEAIGGKENIVAATHCVTRLRFALKDEGKVDKEALERIDVVKGSFSANGQFQVVIGQGLVDKVYNELVE
LTGIGRATKQEIKDAAEAKLNPLQRAIKTLADIFIPILPAIVTAGLLMGINNVLTGPDIFYEGKSFVDVHQEWADLANMI
NLIANTAFVFLPGLIGWSAVTKFGGSPLLGIVLGLMLVHPDLLNAWGWGAAKQEGEIPVWNLFGFDVQKVGYQGQVLPVL
VASYVLAKIELFLRNRIPDAFQLLLVAPLALLVTGFLAFIAIGPITFAIGNAITNLFVGIFDNVPAIGGLLYGALYAPLV
VTGMHHTFLPVDLQLIASTGGTFLWPILVMSNIAQGSAALAMMFVAKDEKLRGLSFTSAVSAYLGITEPAMFGVNLRFRF
PFIAAMTGAAIAGMFITLNKVLAPSIGVGGLPGFLSIVPQKWVPFFIGMAIAIVVPFVLTFVFGKVRKVAR

Sequences:

>Translated_471_residues
MGAYAQAAAQIVEAIGGKENIVAATHCVTRLRFALKDEGKVDKEALERIDVVKGSFSANGQFQVVIGQGLVDKVYNELVE
LTGIGRATKQEIKDAAEAKLNPLQRAIKTLADIFIPILPAIVTAGLLMGINNVLTGPDIFYEGKSFVDVHQEWADLANMI
NLIANTAFVFLPGLIGWSAVTKFGGSPLLGIVLGLMLVHPDLLNAWGWGAAKQEGEIPVWNLFGFDVQKVGYQGQVLPVL
VASYVLAKIELFLRNRIPDAFQLLLVAPLALLVTGFLAFIAIGPITFAIGNAITNLFVGIFDNVPAIGGLLYGALYAPLV
VTGMHHTFLPVDLQLIASTGGTFLWPILVMSNIAQGSAALAMMFVAKDEKLRGLSFTSAVSAYLGITEPAMFGVNLRFRF
PFIAAMTGAAIAGMFITLNKVLAPSIGVGGLPGFLSIVPQKWVPFFIGMAIAIVVPFVLTFVFGKVRKVAR
>Mature_470_residues
GAYAQAAAQIVEAIGGKENIVAATHCVTRLRFALKDEGKVDKEALERIDVVKGSFSANGQFQVVIGQGLVDKVYNELVEL
TGIGRATKQEIKDAAEAKLNPLQRAIKTLADIFIPILPAIVTAGLLMGINNVLTGPDIFYEGKSFVDVHQEWADLANMIN
LIANTAFVFLPGLIGWSAVTKFGGSPLLGIVLGLMLVHPDLLNAWGWGAAKQEGEIPVWNLFGFDVQKVGYQGQVLPVLV
ASYVLAKIELFLRNRIPDAFQLLLVAPLALLVTGFLAFIAIGPITFAIGNAITNLFVGIFDNVPAIGGLLYGALYAPLVV
TGMHHTFLPVDLQLIASTGGTFLWPILVMSNIAQGSAALAMMFVAKDEKLRGLSFTSAVSAYLGITEPAMFGVNLRFRFP
FIAAMTGAAIAGMFITLNKVLAPSIGVGGLPGFLSIVPQKWVPFFIGMAIAIVVPFVLTFVFGKVRKVAR

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=465, Percent_Identity=42.1505376344086, Blast_Score=342, Evalue=2e-95,
Organism=Escherichia coli, GI1790159, Length=464, Percent_Identity=28.0172413793103, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI48994906, Length=473, Percent_Identity=30.6553911205074, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1788769, Length=480, Percent_Identity=29.1666666666667, Blast_Score=147, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011296 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 50311; Mature: 50180

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAYAQAAAQIVEAIGGKENIVAATHCVTRLRFALKDEGKVDKEALERIDVVKGSFSANG
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCC
QFQVVIGQGLVDKVYNELVELTGIGRATKQEIKDAAEAKLNPLQRAIKTLADIFIPILPA
EEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVTAGLLMGINNVLTGPDIFYEGKSFVDVHQEWADLANMINLIANTAFVFLPGLIGWSAV
HHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKFGGSPLLGIVLGLMLVHPDLLNAWGWGAAKQEGEIPVWNLFGFDVQKVGYQGQVLPVL
HHCCCCCHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCEEEECCCCHHHCCCCCCHHHHH
VASYVLAKIELFLRNRIPDAFQLLLVAPLALLVTGFLAFIAIGPITFAIGNAITNLFVGI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FDNVPAIGGLLYGALYAPLVVTGMHHTFLPVDLQLIASTGGTFLWPILVMSNIAQGSAAL
HHCCHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHCCCCHHHHHHHHHHHCCCCHHHH
AMMFVAKDEKLRGLSFTSAVSAYLGITEPAMFGVNLRFRFPFIAAMTGAAIAGMFITLNK
HHHHHHCCCHHCCCHHHHHHHHHHCCCCCHHCCCEEEEECHHHHHHHHHHHHHHHHHHHH
VLAPSIGVGGLPGFLSIVPQKWVPFFIGMAIAIVVPFVLTFVFGKVRKVAR
HHCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GAYAQAAAQIVEAIGGKENIVAATHCVTRLRFALKDEGKVDKEALERIDVVKGSFSANG
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCC
QFQVVIGQGLVDKVYNELVELTGIGRATKQEIKDAAEAKLNPLQRAIKTLADIFIPILPA
EEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVTAGLLMGINNVLTGPDIFYEGKSFVDVHQEWADLANMINLIANTAFVFLPGLIGWSAV
HHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKFGGSPLLGIVLGLMLVHPDLLNAWGWGAAKQEGEIPVWNLFGFDVQKVGYQGQVLPVL
HHCCCCCHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCEEEECCCCHHHCCCCCCHHHHH
VASYVLAKIELFLRNRIPDAFQLLLVAPLALLVTGFLAFIAIGPITFAIGNAITNLFVGI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FDNVPAIGGLLYGALYAPLVVTGMHHTFLPVDLQLIASTGGTFLWPILVMSNIAQGSAAL
HHCCHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHCCCCHHHHHHHHHHHCCCCHHHH
AMMFVAKDEKLRGLSFTSAVSAYLGITEPAMFGVNLRFRFPFIAAMTGAAIAGMFITLNK
HHHHHHCCCHHCCCHHHHHHHHHHCCCCCHHCCCEEEEECHHHHHHHHHHHHHHHHHHHH
VLAPSIGVGGLPGFLSIVPQKWVPFFIGMAIAIVVPFVLTFVFGKVRKVAR
HHCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8917076; 8969503; 9272861; 9384377; 7651129 [H]