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The map label for this gene is treA [H]

Identifier: 138895299

GI number: 138895299

Start: 1730475

End: 1732166

Strand: Reverse

Name: treA [H]

Synonym: GTNG_1643

Alternate gene names: 138895299

Gene position: 1732166-1730475 (Counterclockwise)

Preceding gene: 138895300

Following gene: 138895298

Centisome position: 48.79

GC content: 50.47

Gene sequence:

>1692_bases
GTGTCAACAACACCGTGGTGGAAAAAGGCGGTTGTTTATCAAATTTATCCGAAGAGTTTCCGTGATACGAATGGGGATGG
TATCGGCGATTTGCCGGGCATCATCGAAAAGCTCGATTACTTGAAAGAACTGGGCGTCGATGTCATTTGGCTGACGCCAA
TTTACGCTTCGCCGCAGCGCGATAACGGCTACGACATTAGCGATTATTTCGCCATTCATCACGAGTACGGAACAATGGAT
GATTTTGACCGGTTGCTTGAGGAAGTGCATGCGCGCGGCATGAAGCTTGTCATGGATATGGTCGTCAACCATACGTCGAC
TGACCATGAATGGTTCAAGCAAGCGAGCACATCGAAAACGAACCCGTACCGTCATTTTTACATTTGGCGCGACCCGAAGG
CGGACGGCAGCGCTCCGAACAACTGGCAGTCGAAATTCGGCGGTTCGGCGTGGGAATACGATGAACAAACCGGGCAATAT
TATTTGCATTTGTTCGATGTGACACAAGCCGACTTGAACTGGGAAAACGAAGAGCTGCGCCGCCGCATTTATGACATGAT
GCATTTTTGGCTGAAAAAAGGGGTCGACGGCTTCCGATTGGATGTCATCAACTTGTTGTCCAAAGACCAACATTTTCCAG
ACGATGACGGCTCGATTCCACCGGGGGATGGGCGCCGCTTCTATACGGACGGGCCGCGCATCCATGAATTTTTACAAGAA
ATGAACCGGGAAGTGTTTTCGAAATATGACGTCATGACAGTGGGAGAAATGTCGTCGACGACGATCGATCATTGCATCCG
TTACACGAATCCGGAAAATAACGAGCTGAACATGACGTTTAATTTCCATCACTTGAAAGTCGATTACCCAAACGGGGAAA
AATGGGCCGTCGCTCCGTTTGATTTTCTCGCTTTAAAACGCATTTTGTCGGAGTGGCAGGTGCGAATGCACGAAGGCGGA
GGATGGAATGCGCTCTTTTGGTGCAACCACGACCAACCGCGCATCGTGTCGCGCTACGGTGATGATGGGGAGTATTGGAA
AGAATCAGCGAAGATGCTGGCGACGACGATTCATCTCATGCAAGGGACGCCATACATTTATCAGGGCGAAGAAATCGGCA
TGACCGACCCGAAATTCAACGATATTGGCGACTATCGCGACGTGGAGTCGCTCAATATGTACCGGATCTTGCAAGAGCAA
GGCAAAAGTGAGCAAGAAGTACTCGAGATTTTGCGGCGGAAATCGCGCGACAATTCGCGCACGCCGATGCAATGGGACGA
CAGCTTGCACGCTGGGTTTACATCCGGGACGCCGTGGATTCGCGTTGCCGATAATTATCGGTACATTAACGTGAAGCAGG
CACTGGCCGATCGTGATTCGATTTTTTATCACTATAAGCGGCTCATTGAGCTGCGCAAGCAGTATGACATTATTACGACT
GGCCGTTATGAGCTGCTCCTTGCCGATGATCCGCATCTCTTCGCCTATATGCGTCATGGTGATGGGGAAAAGCTGCTTGT
CGTCAACAACTTTTACCCGGTGGAAACGACGTTTACGCTGCCGGAAGAAGCAGAAGCGAATGACTATACGGGTGAATTGT
TGATCGCCAATTATCCGGACGCACCGGCCGATTTCCGTCGTATGGCGCTACGTCCGTACGAATCGGTTGTTTATCTTCTG
CGCCGTCCATGA

Upstream 100 bases:

>100_bases
TTATTGAGGTAATGATGCATTCGCTGACATACCATTGGCTGCCAACGCCAATGGTATGTTTTTCATTCATTGTCGAAGTC
AACAAACGAGGTGAAGAAAC

Downstream 100 bases:

>100_bases
TACAATACAGACGGTGATGATGATGCATGAAAACAAATATTTAGCTATTTATCACGATCTTGCTTCCCGCATCCGCGACG
GGGAATGGAAGGCGTACGAT

Product: alpha-glucosidase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 563; Mature: 562

Protein sequence:

>563_residues
MSTTPWWKKAVVYQIYPKSFRDTNGDGIGDLPGIIEKLDYLKELGVDVIWLTPIYASPQRDNGYDISDYFAIHHEYGTMD
DFDRLLEEVHARGMKLVMDMVVNHTSTDHEWFKQASTSKTNPYRHFYIWRDPKADGSAPNNWQSKFGGSAWEYDEQTGQY
YLHLFDVTQADLNWENEELRRRIYDMMHFWLKKGVDGFRLDVINLLSKDQHFPDDDGSIPPGDGRRFYTDGPRIHEFLQE
MNREVFSKYDVMTVGEMSSTTIDHCIRYTNPENNELNMTFNFHHLKVDYPNGEKWAVAPFDFLALKRILSEWQVRMHEGG
GWNALFWCNHDQPRIVSRYGDDGEYWKESAKMLATTIHLMQGTPYIYQGEEIGMTDPKFNDIGDYRDVESLNMYRILQEQ
GKSEQEVLEILRRKSRDNSRTPMQWDDSLHAGFTSGTPWIRVADNYRYINVKQALADRDSIFYHYKRLIELRKQYDIITT
GRYELLLADDPHLFAYMRHGDGEKLLVVNNFYPVETTFTLPEEAEANDYTGELLIANYPDAPADFRRMALRPYESVVYLL
RRP

Sequences:

>Translated_563_residues
MSTTPWWKKAVVYQIYPKSFRDTNGDGIGDLPGIIEKLDYLKELGVDVIWLTPIYASPQRDNGYDISDYFAIHHEYGTMD
DFDRLLEEVHARGMKLVMDMVVNHTSTDHEWFKQASTSKTNPYRHFYIWRDPKADGSAPNNWQSKFGGSAWEYDEQTGQY
YLHLFDVTQADLNWENEELRRRIYDMMHFWLKKGVDGFRLDVINLLSKDQHFPDDDGSIPPGDGRRFYTDGPRIHEFLQE
MNREVFSKYDVMTVGEMSSTTIDHCIRYTNPENNELNMTFNFHHLKVDYPNGEKWAVAPFDFLALKRILSEWQVRMHEGG
GWNALFWCNHDQPRIVSRYGDDGEYWKESAKMLATTIHLMQGTPYIYQGEEIGMTDPKFNDIGDYRDVESLNMYRILQEQ
GKSEQEVLEILRRKSRDNSRTPMQWDDSLHAGFTSGTPWIRVADNYRYINVKQALADRDSIFYHYKRLIELRKQYDIITT
GRYELLLADDPHLFAYMRHGDGEKLLVVNNFYPVETTFTLPEEAEANDYTGELLIANYPDAPADFRRMALRPYESVVYLL
RRP
>Mature_562_residues
STTPWWKKAVVYQIYPKSFRDTNGDGIGDLPGIIEKLDYLKELGVDVIWLTPIYASPQRDNGYDISDYFAIHHEYGTMDD
FDRLLEEVHARGMKLVMDMVVNHTSTDHEWFKQASTSKTNPYRHFYIWRDPKADGSAPNNWQSKFGGSAWEYDEQTGQYY
LHLFDVTQADLNWENEELRRRIYDMMHFWLKKGVDGFRLDVINLLSKDQHFPDDDGSIPPGDGRRFYTDGPRIHEFLQEM
NREVFSKYDVMTVGEMSSTTIDHCIRYTNPENNELNMTFNFHHLKVDYPNGEKWAVAPFDFLALKRILSEWQVRMHEGGG
WNALFWCNHDQPRIVSRYGDDGEYWKESAKMLATTIHLMQGTPYIYQGEEIGMTDPKFNDIGDYRDVESLNMYRILQEQG
KSEQEVLEILRRKSRDNSRTPMQWDDSLHAGFTSGTPWIRVADNYRYINVKQALADRDSIFYHYKRLIELRKQYDIITTG
RYELLLADDPHLFAYMRHGDGEKLLVVNNFYPVETTFTLPEEAEANDYTGELLIANYPDAPADFRRMALRPYESVVYLLR
RP

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=529, Percent_Identity=30.0567107750473, Blast_Score=238, Evalue=2e-62,
Organism=Escherichia coli, GI1790687, Length=556, Percent_Identity=57.1942446043165, Blast_Score=649, Evalue=0.0,
Organism=Escherichia coli, GI1786604, Length=193, Percent_Identity=31.0880829015544, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87081873, Length=149, Percent_Identity=27.5167785234899, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI25147709, Length=585, Percent_Identity=25.982905982906, Blast_Score=132, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI32565753, Length=206, Percent_Identity=30.5825242718447, Blast_Score=111, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6322245, Length=579, Percent_Identity=41.4507772020725, Blast_Score=445, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6321726, Length=578, Percent_Identity=39.9653979238754, Blast_Score=407, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6324416, Length=580, Percent_Identity=40.1724137931035, Blast_Score=400, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6322241, Length=578, Percent_Identity=40.1384083044983, Blast_Score=397, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6322021, Length=578, Percent_Identity=40.1384083044983, Blast_Score=397, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6321731, Length=580, Percent_Identity=39.1379310344828, Blast_Score=387, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6319776, Length=580, Percent_Identity=38.9655172413793, Blast_Score=385, Evalue=1e-108,
Organism=Drosophila melanogaster, GI221330053, Length=594, Percent_Identity=33.5016835016835, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24586599, Length=588, Percent_Identity=32.8231292517007, Blast_Score=275, Evalue=5e-74,
Organism=Drosophila melanogaster, GI24583747, Length=551, Percent_Identity=35.3901996370236, Blast_Score=268, Evalue=5e-72,
Organism=Drosophila melanogaster, GI24583749, Length=551, Percent_Identity=35.3901996370236, Blast_Score=268, Evalue=6e-72,
Organism=Drosophila melanogaster, GI45549022, Length=545, Percent_Identity=33.7614678899083, Blast_Score=267, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24586597, Length=542, Percent_Identity=33.3948339483395, Blast_Score=267, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24583745, Length=521, Percent_Identity=33.7811900191939, Blast_Score=265, Evalue=9e-71,
Organism=Drosophila melanogaster, GI24586593, Length=571, Percent_Identity=31.6987740805604, Blast_Score=252, Evalue=4e-67,
Organism=Drosophila melanogaster, GI24586589, Length=530, Percent_Identity=33.7735849056604, Blast_Score=252, Evalue=6e-67,
Organism=Drosophila melanogaster, GI24586591, Length=530, Percent_Identity=32.8301886792453, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI24586587, Length=594, Percent_Identity=29.1245791245791, Blast_Score=238, Evalue=7e-63,
Organism=Drosophila melanogaster, GI281360393, Length=516, Percent_Identity=28.4883720930233, Blast_Score=173, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 66289; Mature: 66158

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTPWWKKAVVYQIYPKSFRDTNGDGIGDLPGIIEKLDYLKELGVDVIWLTPIYASPQR
CCCCCCHHHEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECEECCCCC
DNGYDISDYFAIHHEYGTMDDFDRLLEEVHARGMKLVMDMVVNHTSTDHEWFKQASTSKT
CCCCCHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
NPYRHFYIWRDPKADGSAPNNWQSKFGGSAWEYDEQTGQYYLHLFDVTQADLNWENEELR
CCCEEEEEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHH
RRIYDMMHFWLKKGVDGFRLDVINLLSKDQHFPDDDGSIPPGDGRRFYTDGPRIHEFLQE
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHH
MNREVFSKYDVMTVGEMSSTTIDHCIRYTNPENNELNMTFNFHHLKVDYPNGEKWAVAPF
HHHHHHHHCCEEEECCCCHHHHHHHHHCCCCCCCEEEEEEEEEEEEEECCCCCEEEECCH
DFLALKRILSEWQVRMHEGGGWNALFWCNHDQPRIVSRYGDDGEYWKESAKMLATTIHLM
HHHHHHHHHHHHHEEEECCCCEEEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHH
QGTPYIYQGEEIGMTDPKFNDIGDYRDVESLNMYRILQEQGKSEQEVLEILRRKSRDNSR
CCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
TPMQWDDSLHAGFTSGTPWIRVADNYRYINVKQALADRDSIFYHYKRLIELRKQYDIITT
CCCCCCCCCCCCCCCCCCEEEEECCEEEEEHHHHHCCHHHHHHHHHHHHHHHHHCCEEEC
GRYELLLADDPHLFAYMRHGDGEKLLVVNNFYPVETTFTLPEEAEANDYTGELLIANYPD
CCEEEEEECCCCEEEEEEECCCCEEEEEECEECCCEEEECCCCCCCCCCCCEEEEEECCC
APADFRRMALRPYESVVYLLRRP
CCHHHHHHHCCCHHHHHHHHCCC
>Mature Secondary Structure 
STTPWWKKAVVYQIYPKSFRDTNGDGIGDLPGIIEKLDYLKELGVDVIWLTPIYASPQR
CCCCCHHHEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECEECCCCC
DNGYDISDYFAIHHEYGTMDDFDRLLEEVHARGMKLVMDMVVNHTSTDHEWFKQASTSKT
CCCCCHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
NPYRHFYIWRDPKADGSAPNNWQSKFGGSAWEYDEQTGQYYLHLFDVTQADLNWENEELR
CCCEEEEEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHH
RRIYDMMHFWLKKGVDGFRLDVINLLSKDQHFPDDDGSIPPGDGRRFYTDGPRIHEFLQE
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHH
MNREVFSKYDVMTVGEMSSTTIDHCIRYTNPENNELNMTFNFHHLKVDYPNGEKWAVAPF
HHHHHHHHCCEEEECCCCHHHHHHHHHCCCCCCCEEEEEEEEEEEEEECCCCCEEEECCH
DFLALKRILSEWQVRMHEGGGWNALFWCNHDQPRIVSRYGDDGEYWKESAKMLATTIHLM
HHHHHHHHHHHHHEEEECCCCEEEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHH
QGTPYIYQGEEIGMTDPKFNDIGDYRDVESLNMYRILQEQGKSEQEVLEILRRKSRDNSR
CCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
TPMQWDDSLHAGFTSGTPWIRVADNYRYINVKQALADRDSIFYHYKRLIELRKQYDIITT
CCCCCCCCCCCCCCCCCCEEEEECCEEEEEHHHHHCCHHHHHHHHHHHHHHHHHCCEEEC
GRYELLLADDPHLFAYMRHGDGEKLLVVNNFYPVETTFTLPEEAEANDYTGELLIANYPD
CCEEEEEECCCCEEEEEEECCCCEEEEEECEECCCEEEECCCCCCCCCCCCEEEEEECCC
APADFRRMALRPYESVVYLLRRP
CCHHHHHHHCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7651129; 8969503; 9384377; 7751281 [H]