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The map label for this gene is csd [H]

Identifier: 138895295

GI number: 138895295

Start: 1725694

End: 1727193

Strand: Reverse

Name: csd [H]

Synonym: GTNG_1639

Alternate gene names: 138895295

Gene position: 1727193-1725694 (Counterclockwise)

Preceding gene: 138895296

Following gene: 138895294

Centisome position: 48.65

GC content: 52.33

Gene sequence:

>1500_bases
ATGACAATTCGCGCGACGATCGGGAGCGCAACATATACATGTCGCGGCGAGCTTGAGACACACTTCCAGCCGTTTCGCGA
CGGAACAATCGGCCGGTTTCACCCATTTTCTACACCATTTGGTGAACAGCGGCTCATTTACGCCGATTGGACAGCAAGCG
GGCGGTTATACCGACCGATTGAAGAAAAAATGGTGCACGAGCTCGGCCCGTTTGTCGGCAACACGCATACGGAGTCGAAT
GTGACCGGAACGAAAATGACGCTTGCGTATCAATATGCGAAAGAAATTATCAAACAGCACGTTCACGCAGGGAGAGGCGA
TGTGTTGATCATGCAAGGAGCCGGCATGACGAGCGCTGTCAACAAACTGCAGCGCCTGCTTGGCTTGCGTGTGCCAGAAC
AATGGAAATCGCGCCTGGCGCTTACTAATGACGAACGACCGGTCGTTTTTGTCACGCATATGGAGCACCATTCGAATTTA
TTATCATGGGCCGAAACGATCGCTGAGGTCGTAACGGTTCGTCCGACCGCTAGCGGCGAGGTGGACCTTGACCATTTACG
CGAATTGCTTGAACGCTACCGCCATCGGCCGCAAAAAATCGGTGCATTCACTGCCTGCTCGAACGTCACCGGCCTAGAGA
CGCCATACCATGAACTCGCTAAACTTATGCATGAATACGGCGGGCTTTGTTTCGTTGATTTTGCCGCTTCCGCTCCGTAC
GTCCGCATTGATATGCATCCGGATGATCCAATGGAAAAGCTTGATGCGATTTATTTTTCTCCGCATAAGTTTCTTGGCGG
GCCGGGGAGTGCCGGCGTGCTCGTGTTTGACGGACGCCTTTACCGCCAGCATGCGCCGGATCATCCGGGCGGTGGGACGG
TGTATTGGACCGATCCATGGGGGCATTATGAGTACGTAGAGGCGATTGAAGAACGGGAAGACGGGGGCACACCGCCGTTT
TGGCAAACGATTAAAGCAGCGCTCGCCATTCAACTGAAAGAACAGATGAATATTGCGAAGATGCGCGCTCGGGAAAAAGA
GCTCGTTTCGCTTCTCCTGCCGGCGCTGCAGAAAATCCCCGGCGTTCATGTGCTAGAAGGGCATCGAAGTGATCGGCTTG
GTATTGTTTCGTTTGTAATCGAAGGACTTCATTATAATCTTGTCGTCAAACTGCTAAACGACCGCTTTGGCATTCAGGCG
CGCGGCGGCTGCTCATGCGCCGGGCCGTACGGACATTACTTGCTTGGCATTGACAAAGAACAGTCGGCTGCCTTGCTTGA
GGAAGTCAAAAGCGGCAACGCCCTCGCCAAACCAGGATGGGTACGTTTATCGCTCCATCCGACGATGACAAACGAAGAAG
TGTACACGATTATTCATGCTGTTCGTCAAATTGCACGTGATGGCTGCCGCTGGCAAGACGAATACGAATATGACGAAGCA
AAAAACGAGTTTGTTCACCGTGGCGATGATCGGTATATTCGGTATTTTTTTCTCTTTTAA

Upstream 100 bases:

>100_bases
ACAAGGCGGTTTTTTTGTCTTCATTCGTTTTCTCTGGACCAAACTGCCCAATGGCCACATATGGTATGAGTAGGGTGACT
CAGAAAAGGGAGGAACGATC

Downstream 100 bases:

>100_bases
TCTTCGTTTTGGTTATCTTTGCTGTCCTAGTCGTCTGAAGACCAAGACGGCTATTTTTTATCTCCCCGAATTCAGGATGA
CATGGGCATCGGTGGGCGTT

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MTIRATIGSATYTCRGELETHFQPFRDGTIGRFHPFSTPFGEQRLIYADWTASGRLYRPIEEKMVHELGPFVGNTHTESN
VTGTKMTLAYQYAKEIIKQHVHAGRGDVLIMQGAGMTSAVNKLQRLLGLRVPEQWKSRLALTNDERPVVFVTHMEHHSNL
LSWAETIAEVVTVRPTASGEVDLDHLRELLERYRHRPQKIGAFTACSNVTGLETPYHELAKLMHEYGGLCFVDFAASAPY
VRIDMHPDDPMEKLDAIYFSPHKFLGGPGSAGVLVFDGRLYRQHAPDHPGGGTVYWTDPWGHYEYVEAIEEREDGGTPPF
WQTIKAALAIQLKEQMNIAKMRAREKELVSLLLPALQKIPGVHVLEGHRSDRLGIVSFVIEGLHYNLVVKLLNDRFGIQA
RGGCSCAGPYGHYLLGIDKEQSAALLEEVKSGNALAKPGWVRLSLHPTMTNEEVYTIIHAVRQIARDGCRWQDEYEYDEA
KNEFVHRGDDRYIRYFFLF

Sequences:

>Translated_499_residues
MTIRATIGSATYTCRGELETHFQPFRDGTIGRFHPFSTPFGEQRLIYADWTASGRLYRPIEEKMVHELGPFVGNTHTESN
VTGTKMTLAYQYAKEIIKQHVHAGRGDVLIMQGAGMTSAVNKLQRLLGLRVPEQWKSRLALTNDERPVVFVTHMEHHSNL
LSWAETIAEVVTVRPTASGEVDLDHLRELLERYRHRPQKIGAFTACSNVTGLETPYHELAKLMHEYGGLCFVDFAASAPY
VRIDMHPDDPMEKLDAIYFSPHKFLGGPGSAGVLVFDGRLYRQHAPDHPGGGTVYWTDPWGHYEYVEAIEEREDGGTPPF
WQTIKAALAIQLKEQMNIAKMRAREKELVSLLLPALQKIPGVHVLEGHRSDRLGIVSFVIEGLHYNLVVKLLNDRFGIQA
RGGCSCAGPYGHYLLGIDKEQSAALLEEVKSGNALAKPGWVRLSLHPTMTNEEVYTIIHAVRQIARDGCRWQDEYEYDEA
KNEFVHRGDDRYIRYFFLF
>Mature_498_residues
TIRATIGSATYTCRGELETHFQPFRDGTIGRFHPFSTPFGEQRLIYADWTASGRLYRPIEEKMVHELGPFVGNTHTESNV
TGTKMTLAYQYAKEIIKQHVHAGRGDVLIMQGAGMTSAVNKLQRLLGLRVPEQWKSRLALTNDERPVVFVTHMEHHSNLL
SWAETIAEVVTVRPTASGEVDLDHLRELLERYRHRPQKIGAFTACSNVTGLETPYHELAKLMHEYGGLCFVDFAASAPYV
RIDMHPDDPMEKLDAIYFSPHKFLGGPGSAGVLVFDGRLYRQHAPDHPGGGTVYWTDPWGHYEYVEAIEEREDGGTPPFW
QTIKAALAIQLKEQMNIAKMRAREKELVSLLLPALQKIPGVHVLEGHRSDRLGIVSFVIEGLHYNLVVKLLNDRFGIQAR
GGCSCAGPYGHYLLGIDKEQSAALLEEVKSGNALAKPGWVRLSLHPTMTNEEVYTIIHAVRQIARDGCRWQDEYEYDEAK
NEFVHRGDDRYIRYFFLF

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=332, Percent_Identity=26.2048192771084, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789175, Length=420, Percent_Identity=26.1904761904762, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193211090, Length=493, Percent_Identity=32.2515212981744, Blast_Score=251, Evalue=5e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 56499; Mature: 56368

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRATIGSATYTCRGELETHFQPFRDGTIGRFHPFSTPFGEQRLIYADWTASGRLYRPI
CEEEEEECCCEEEEECCHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECCH
EEKMVHELGPFVGNTHTESNVTGTKMTLAYQYAKEIIKQHVHAGRGDVLIMQGAGMTSAV
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHH
NKLQRLLGLRVPEQWKSRLALTNDERPVVFVTHMEHHSNLLSWAETIAEVVTVRPTASGE
HHHHHHHCCCCCHHHHHCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHEECCCCCCC
VDLDHLRELLERYRHRPQKIGAFTACSNVTGLETPYHELAKLMHEYGGLCFVDFAASAPY
CCHHHHHHHHHHHHCCHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCE
VRIDMHPDDPMEKLDAIYFSPHKFLGGPGSAGVLVFDGRLYRQHAPDHPGGGTVYWTDPW
EEEECCCCCHHHHHHHHEECCHHHCCCCCCCCEEEECCEEHHCCCCCCCCCCEEEECCCC
GHYEYVEAIEEREDGGTPPFWQTIKAALAIQLKEQMNIAKMRAREKELVSLLLPALQKIP
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVHVLEGHRSDRLGIVSFVIEGLHYNLVVKLLNDRFGIQARGGCSCAGPYGHYLLGIDKE
CCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCH
QSAALLEEVKSGNALAKPGWVRLSLHPTMTNEEVYTIIHAVRQIARDGCRWQDEYEYDEA
HHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
KNEFVHRGDDRYIRYFFLF
HHHHHHCCCCCEEEEEEEC
>Mature Secondary Structure 
TIRATIGSATYTCRGELETHFQPFRDGTIGRFHPFSTPFGEQRLIYADWTASGRLYRPI
EEEEEECCCEEEEECCHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECCH
EEKMVHELGPFVGNTHTESNVTGTKMTLAYQYAKEIIKQHVHAGRGDVLIMQGAGMTSAV
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHH
NKLQRLLGLRVPEQWKSRLALTNDERPVVFVTHMEHHSNLLSWAETIAEVVTVRPTASGE
HHHHHHHCCCCCHHHHHCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHEECCCCCCC
VDLDHLRELLERYRHRPQKIGAFTACSNVTGLETPYHELAKLMHEYGGLCFVDFAASAPY
CCHHHHHHHHHHHHCCHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCE
VRIDMHPDDPMEKLDAIYFSPHKFLGGPGSAGVLVFDGRLYRQHAPDHPGGGTVYWTDPW
EEEECCCCCHHHHHHHHEECCHHHCCCCCCCCEEEECCEEHHCCCCCCCCCCEEEECCCC
GHYEYVEAIEEREDGGTPPFWQTIKAALAIQLKEQMNIAKMRAREKELVSLLLPALQKIP
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVHVLEGHRSDRLGIVSFVIEGLHYNLVVKLLNDRFGIQARGGCSCAGPYGHYLLGIDKE
CCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCH
QSAALLEEVKSGNALAKPGWVRLSLHPTMTNEEVYTIIHAVRQIARDGCRWQDEYEYDEA
HHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
KNEFVHRGDDRYIRYFFLF
HHHHHHCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]