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The map label for this gene is ydbM [H]

Identifier: 138895294

GI number: 138895294

Start: 1724325

End: 1725518

Strand: Reverse

Name: ydbM [H]

Synonym: GTNG_1638

Alternate gene names: 138895294

Gene position: 1725518-1724325 (Counterclockwise)

Preceding gene: 138895295

Following gene: 138895290

Centisome position: 48.6

GC content: 57.54

Gene sequence:

>1194_bases
ATGAACGAATTGTATCATTTGCTCGTGCGAAACGAGCGGGAACGGGAACTGTATGAACAAGCTCGGCACCTCGCTGAGCG
TTTTGCGGCGCGGGCGGCAGATTATGACGAACGGGCGGAGTTCCCGTTTGCTGATTTTGCTGACTTAAAAGAAGCCGGAT
TTCTTTCGCTCACGGTTCCCACCGAATACGGTGGCCACGGGGCGTCGCTTTATGAATTGGTACTTGTGCAAGAAATGCTC
GCTCAAGGCAGCGGCGCCACCGCCTTGTCGTTCGGATGGCACGCGAGCATTCTGATGCGTCTGTTTTTACTCCGCCGCTG
GCCGGAATCGACGCTCGCCCGCTTGGCCGAAGAAGTTGTCAAACGCCATGCGCTCATTAACAGCGCCCACTCCGAACGGG
CAACCGGCAGCCCAGCGCGCGGCGGAAAACCTGAAACAAAAGCCGCCCTCCGCAATGGCCGCTTTGTGCTCTGCGGGCGC
AAATCGTTTGCCTCGTTGGCCCCGGCGTTAGATTACGTATTGATTTCCGCCACCATCGAAGACAGCGGCGAAGTCGGCGA
ATTTCTCACCCCTATGTCCGCTACAGGCATGCGCATTGAGCCGACATGGAACACGCTCGGTATGCGGGCGACGCGTAGCG
ACGACCTCATCCTTGATGGTGTTGAAGTCGAGAAGGATGCGCTTGTGGAAATCCTCGGGAAGTCGAATGAAACCGCTCCA
GCACAAGGATGGTTGTTGCACGTTCCGGCTTGCTACTTAGGCATCGCCATTGCGGCTCGCAATGAAGCGATCCGCTTCGC
GCAGACGTATCAGCCGAACACATTGTCCCATCCGATCGCTTCAACGCCAGAAGTGCAGCGAAAGATCGCCGAAATGGAAT
GGCGGCTTGCCCACGCGCGCCATTTTCTGTACGCGATCGCTGACTTATGGGATCGCTATCCGGATAAACGAGCCGAGATG
AAAGAGGAGCTGGCGGCCGCGAAGCTAGTTGCCACAAATACAGCACTCGAGGTCGTCGATATGGCGATGCGCATCGTCGG
CGGGCAAAGCTTGTTTGCTGACAATCCGCTCGGCCGCTATTACCGCGACATCCGCGCCGGGCTGCATAACCCACCCGCTG
ATGACTTGACGCTCGCATGGCTGGCTAAACGAGCACTATCTCACCACCCGCTAGGCGGCTCAAGCAACCAATAA

Upstream 100 bases:

>100_bases
GATGACATGGGCATCGGTGGGCGTTTAAGCGTTTTTGTTTTCACCCTTCATCAAAACCGGTACAATGAAATCATCTTAAC
AACAAAAGAAGGGGAGAGCG

Downstream 100 bases:

>100_bases
AAGAGCTTTCTCTAAGAGGAGGCATCAGATGCGGGTAACACAAAAAGGGAGGATTCAAAGAGCCGGCTAAACACCTATAT
AGAACAGCAAAATCATTTAA

Product: Short-chain-specific acyl-CoA dehydrogenase

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MNELYHLLVRNERERELYEQARHLAERFAARAADYDERAEFPFADFADLKEAGFLSLTVPTEYGGHGASLYELVLVQEML
AQGSGATALSFGWHASILMRLFLLRRWPESTLARLAEEVVKRHALINSAHSERATGSPARGGKPETKAALRNGRFVLCGR
KSFASLAPALDYVLISATIEDSGEVGEFLTPMSATGMRIEPTWNTLGMRATRSDDLILDGVEVEKDALVEILGKSNETAP
AQGWLLHVPACYLGIAIAARNEAIRFAQTYQPNTLSHPIASTPEVQRKIAEMEWRLAHARHFLYAIADLWDRYPDKRAEM
KEELAAAKLVATNTALEVVDMAMRIVGGQSLFADNPLGRYYRDIRAGLHNPPADDLTLAWLAKRALSHHPLGGSSNQ

Sequences:

>Translated_397_residues
MNELYHLLVRNERERELYEQARHLAERFAARAADYDERAEFPFADFADLKEAGFLSLTVPTEYGGHGASLYELVLVQEML
AQGSGATALSFGWHASILMRLFLLRRWPESTLARLAEEVVKRHALINSAHSERATGSPARGGKPETKAALRNGRFVLCGR
KSFASLAPALDYVLISATIEDSGEVGEFLTPMSATGMRIEPTWNTLGMRATRSDDLILDGVEVEKDALVEILGKSNETAP
AQGWLLHVPACYLGIAIAARNEAIRFAQTYQPNTLSHPIASTPEVQRKIAEMEWRLAHARHFLYAIADLWDRYPDKRAEM
KEELAAAKLVATNTALEVVDMAMRIVGGQSLFADNPLGRYYRDIRAGLHNPPADDLTLAWLAKRALSHHPLGGSSNQ
>Mature_397_residues
MNELYHLLVRNERERELYEQARHLAERFAARAADYDERAEFPFADFADLKEAGFLSLTVPTEYGGHGASLYELVLVQEML
AQGSGATALSFGWHASILMRLFLLRRWPESTLARLAEEVVKRHALINSAHSERATGSPARGGKPETKAALRNGRFVLCGR
KSFASLAPALDYVLISATIEDSGEVGEFLTPMSATGMRIEPTWNTLGMRATRSDDLILDGVEVEKDALVEILGKSNETAP
AQGWLLHVPACYLGIAIAARNEAIRFAQTYQPNTLSHPIASTPEVQRKIAEMEWRLAHARHFLYAIADLWDRYPDKRAEM
KEELAAAKLVATNTALEVVDMAMRIVGGQSLFADNPLGRYYRDIRAGLHNPPADDLTLAWLAKRALSHHPLGGSSNQ

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=368, Percent_Identity=25, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI226958414, Length=340, Percent_Identity=24.4117647058824, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI4557233, Length=380, Percent_Identity=26.3157894736842, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI4501859, Length=369, Percent_Identity=24.390243902439, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1786223, Length=372, Percent_Identity=24.4623655913978, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081958, Length=365, Percent_Identity=26.027397260274, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17538396, Length=372, Percent_Identity=25.2688172043011, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17508101, Length=359, Percent_Identity=22.8412256267409, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17506239, Length=339, Percent_Identity=23.8938053097345, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17534899, Length=374, Percent_Identity=23.7967914438503, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355753, Length=370, Percent_Identity=24.5945945945946, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24646207, Length=376, Percent_Identity=26.063829787234, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=24.2021276595745, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 44032; Mature: 44032

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELYHLLVRNERERELYEQARHLAERFAARAADYDERAEFPFADFADLKEAGFLSLTVP
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHCCEEEEECC
TEYGGHGASLYELVLVQEMLAQGSGATALSFGWHASILMRLFLLRRWPESTLARLAEEVV
CCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KRHALINSAHSERATGSPARGGKPETKAALRNGRFVLCGRKSFASLAPALDYVLISATIE
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCEEEECCHHHHHHHHHHHHHEEEEEEC
DSGEVGEFLTPMSATGMRIEPTWNTLGMRATRSDDLILDGVEVEKDALVEILGKSNETAP
CCCCHHHHHCCCCCCCEEECCCHHHHCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCC
AQGWLLHVPACYLGIAIAARNEAIRFAQTYQPNTLSHPIASTPEVQRKIAEMEWRLAHAR
CCCCEEECCHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
HFLYAIADLWDRYPDKRAEMKEELAAAKLVATNTALEVVDMAMRIVGGQSLFADNPLGRY
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHH
YRDIRAGLHNPPADDLTLAWLAKRALSHHPLGGSSNQ
HHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNELYHLLVRNERERELYEQARHLAERFAARAADYDERAEFPFADFADLKEAGFLSLTVP
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHCCEEEEECC
TEYGGHGASLYELVLVQEMLAQGSGATALSFGWHASILMRLFLLRRWPESTLARLAEEVV
CCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KRHALINSAHSERATGSPARGGKPETKAALRNGRFVLCGRKSFASLAPALDYVLISATIE
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCEEEECCHHHHHHHHHHHHHEEEEEEC
DSGEVGEFLTPMSATGMRIEPTWNTLGMRATRSDDLILDGVEVEKDALVEILGKSNETAP
CCCCHHHHHCCCCCCCEEECCCHHHHCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCC
AQGWLLHVPACYLGIAIAARNEAIRFAQTYQPNTLSHPIASTPEVQRKIAEMEWRLAHAR
CCCCEEECCHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
HFLYAIADLWDRYPDKRAEMKEELAAAKLVATNTALEVVDMAMRIVGGQSLFADNPLGRY
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHH
YRDIRAGLHNPPADDLTLAWLAKRALSHHPLGGSSNQ
HHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]