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The map label for this gene is kipI [H]

Identifier: 138895013

GI number: 138895013

Start: 1437933

End: 1438634

Strand: Direct

Name: kipI [H]

Synonym: GTNG_1351

Alternate gene names: 138895013

Gene position: 1437933-1438634 (Clockwise)

Preceding gene: 138895012

Following gene: 138895014

Centisome position: 40.5

GC content: 56.27

Gene sequence:

>702_bases
ATGGAATACACGTTGTTTCCGTTATGCGAATACGCGGTGACCGTTCGATTTGCCAGTTACATTGACGAAGCCGTAAACGA
TATCGTTCACGAAACAGCAGCCCGGCTTCAGGGAGAGAGAAAAGAAGGCATCAAGGAAATCGTGCCGGCGTTTTCCTCAC
TGACCGTCTATTATGATCCGGTGGTGGCCGGAAATTATGCTGACGTATGTGCCTGGCTGCGCGAGAATATCGGATCGACC
GGACAGGCTGCCCGCCATTCGACGCGAACCATCGTCATTCCCGTTTGTTACGGCGGCGAGTTCGGGCCGGATTTAGCGGA
TGTCGCCCGCTTTCATGGGATGACGGAAGATGAAGTGGTGGCGCTTCATTCCTCGGGCCGTTACCGCGTCTATATGATCG
GTTTTTCACCCGGGTTTGCCTATTTAGGGGGCTTATCACCGCGTTTGGCGACGCCGAGGAGGCCGGTGCCGCGCACAACG
GTGCCTGCCGGTTCGGTCGGCATCGCCGGCGGACAGACGGGTGTTTATCCGCTCGCGACGCCAGGTGGTTGGCAATTGAT
TGGCCGGACACCGCTTCGGCTGTTTGATCCGCATCGGGAGAAACCAAGCTTGCTTTCAGCGGGTGACATCGTTGAGTTTC
GCCGGATTACCGCTGAGGAATTTGCACGTTGGAGAGAGGAACATGATGATGGACGTCATTGA

Upstream 100 bases:

>100_bases
CACGTTTTTCGCCCGATGATGTGGTGCGCATCGTTCCGCTATTAAAGCAGGCGGCGATGGATATCTCACGTGAACTTGGT
TTTCAAGGGAAGGGGTAACG

Downstream 100 bases:

>100_bases
TGGTGGATTTTTTACAACTGTCCAAGATGGCGGGCGCATCGGCTATCGAAATGCCGGTGTGCCGGTTGGTGGGGTGATGG
ACGCTTGGGCGTATCGCCTT

Product: allophanate hydrolase subunit 1

Products: NA

Alternate protein names: Sporulation inhibitor kipI [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MEYTLFPLCEYAVTVRFASYIDEAVNDIVHETAARLQGERKEGIKEIVPAFSSLTVYYDPVVAGNYADVCAWLRENIGST
GQAARHSTRTIVIPVCYGGEFGPDLADVARFHGMTEDEVVALHSSGRYRVYMIGFSPGFAYLGGLSPRLATPRRPVPRTT
VPAGSVGIAGGQTGVYPLATPGGWQLIGRTPLRLFDPHREKPSLLSAGDIVEFRRITAEEFARWREEHDDGRH

Sequences:

>Translated_233_residues
MEYTLFPLCEYAVTVRFASYIDEAVNDIVHETAARLQGERKEGIKEIVPAFSSLTVYYDPVVAGNYADVCAWLRENIGST
GQAARHSTRTIVIPVCYGGEFGPDLADVARFHGMTEDEVVALHSSGRYRVYMIGFSPGFAYLGGLSPRLATPRRPVPRTT
VPAGSVGIAGGQTGVYPLATPGGWQLIGRTPLRLFDPHREKPSLLSAGDIVEFRRITAEEFARWREEHDDGRH
>Mature_233_residues
MEYTLFPLCEYAVTVRFASYIDEAVNDIVHETAARLQGERKEGIKEIVPAFSSLTVYYDPVVAGNYADVCAWLRENIGST
GQAARHSTRTIVIPVCYGGEFGPDLADVARFHGMTEDEVVALHSSGRYRVYMIGFSPGFAYLGGLSPRLATPRRPVPRTT
VPAGSVGIAGGQTGVYPLATPGGWQLIGRTPLRLFDPHREKPSLLSAGDIVEFRRITAEEFARWREEHDDGRH

Specific function: Is a potent inhibitor of the autophosphorylation reaction of kinase A and its reverse reaction, but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. KipI is an inhibitor of the catalytic domain of kinase

COG id: COG2049

COG function: function code E; Allophanate hydrolase subunit 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786929, Length=207, Percent_Identity=45.8937198067633, Blast_Score=158, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003833
- InterPro:   IPR020899
- InterPro:   IPR010016
- InterPro:   IPR002130 [H]

Pfam domain/function: PF02682 AHS1 [H]

EC number: NA

Molecular weight: Translated: 25686; Mature: 25686

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYTLFPLCEYAVTVRFASYIDEAVNDIVHETAARLQGERKEGIKEIVPAFSSLTVYYDP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCEEEEECC
VVAGNYADVCAWLRENIGSTGQAARHSTRTIVIPVCYGGEFGPDLADVARFHGMTEDEVV
EECCCHHHHHHHHHHHCCCCCHHHHCCCCEEEEEEEECCCCCCCHHHHHHHCCCCCCCEE
ALHSSGRYRVYMIGFSPGFAYLGGLSPRLATPRRPVPRTTVPAGSVGIAGGQTGVYPLAT
EEECCCCEEEEEEEECCCHHHHCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEEC
PGGWQLIGRTPLRLFDPHREKPSLLSAGDIVEFRRITAEEFARWREEHDDGRH
CCCCEEECCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEYTLFPLCEYAVTVRFASYIDEAVNDIVHETAARLQGERKEGIKEIVPAFSSLTVYYDP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCEEEEECC
VVAGNYADVCAWLRENIGSTGQAARHSTRTIVIPVCYGGEFGPDLADVARFHGMTEDEVV
EECCCHHHHHHHHHHHCCCCCHHHHCCCCEEEEEEEECCCCCCCHHHHHHHCCCCCCCEE
ALHSSGRYRVYMIGFSPGFAYLGGLSPRLATPRRPVPRTTVPAGSVGIAGGQTGVYPLAT
EEECCCCEEEEEEEECCCHHHHCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEEC
PGGWQLIGRTPLRLFDPHREKPSLLSAGDIVEFRRITAEEFARWREEHDDGRH
CCCCEEECCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 10568751 [H]