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The map label for this gene is kipR [H]

Identifier: 138895012

GI number: 138895012

Start: 1437181

End: 1437930

Strand: Direct

Name: kipR [H]

Synonym: GTNG_1350

Alternate gene names: 138895012

Gene position: 1437181-1437930 (Clockwise)

Preceding gene: 138895011

Following gene: 138895013

Centisome position: 40.48

GC content: 52.93

Gene sequence:

>750_bases
ATGAATAAAACGGTTTTGAAAACAAAAGAGCTGCTAGATTTGTTTCTTGATTGCGAGCGGTTAACGCTGCCGGAGATGGT
TGCGCGGCTTCGGATGCCGAAAACGTCGGTGTACCGGATGGCGCAGTCGCTTGTGGCGCTAGGCTTTTTGCAAAAACAAG
GCGACCAGTATGAACTCGGCTTGTCGTTATTGACGTTCGGAGCGCTTGTCGCCGAGCGGCTCGATATTCGTCGAGTGGCG
CTGCCGGTCATGGAGCGGCTGAAAGAGGAGACGAAGGAAGCAGTGAATTTAGTCATCCGCGACGGCGATGAAGCGCTGTA
TATCGAAAAAGTGGAGACGTCCGAACCGGTGCGCGTCTATACGAAAGTTGGGCGGCGTGCACCGCTGTATGCTGGGGCGT
GCCCGCGCGTCTTGCTTGCGTTTATGGATGAAGTTGACCGGGAACGGTATTTAGAACAAGTGGAACTAGTGAAAATCGCT
AAATGTACGGTGACAGACAAACAAGTGTTGCGCCGATTGGTAGAAGAAGGCCGGAATCAAGGCTATACGGTTAGTTGTTC
TGAGCTGGAAAACTACTCTGCTGCTGTTGCTGTGCCGATTTTCAACCATGAAGGGGCAGCGGTTGCTGGGTTGAGCGTCG
CCGGTCCGGAACCACGTTTTTCGCCCGATGATGTGGTGCGCATCGTTCCGCTATTAAAGCAGGCGGCGATGGATATCTCA
CGTGAACTTGGTTTTCAAGGGAAGGGGTAA

Upstream 100 bases:

>100_bases
TGTTTGTTTTTTTGTAGAAAATAATTGGACTTTTCGTTATAATTGAAATAAAATTCATATTTCGGAATTATCATTCCGAT
ATTCGGAACAAGGAGAGGCC

Downstream 100 bases:

>100_bases
CGATGGAATACACGTTGTTTCCGTTATGCGAATACGCGGTGACCGTTCGATTTGCCAGTTACATTGACGAAGCCGTAAAC
GATATCGTTCACGAAACAGC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MNKTVLKTKELLDLFLDCERLTLPEMVARLRMPKTSVYRMAQSLVALGFLQKQGDQYELGLSLLTFGALVAERLDIRRVA
LPVMERLKEETKEAVNLVIRDGDEALYIEKVETSEPVRVYTKVGRRAPLYAGACPRVLLAFMDEVDRERYLEQVELVKIA
KCTVTDKQVLRRLVEEGRNQGYTVSCSELENYSAAVAVPIFNHEGAAVAGLSVAGPEPRFSPDDVVRIVPLLKQAAMDIS
RELGFQGKG

Sequences:

>Translated_249_residues
MNKTVLKTKELLDLFLDCERLTLPEMVARLRMPKTSVYRMAQSLVALGFLQKQGDQYELGLSLLTFGALVAERLDIRRVA
LPVMERLKEETKEAVNLVIRDGDEALYIEKVETSEPVRVYTKVGRRAPLYAGACPRVLLAFMDEVDRERYLEQVELVKIA
KCTVTDKQVLRRLVEEGRNQGYTVSCSELENYSAAVAVPIFNHEGAAVAGLSVAGPEPRFSPDDVVRIVPLLKQAAMDIS
RELGFQGKG
>Mature_249_residues
MNKTVLKTKELLDLFLDCERLTLPEMVARLRMPKTSVYRMAQSLVALGFLQKQGDQYELGLSLLTFGALVAERLDIRRVA
LPVMERLKEETKEAVNLVIRDGDEALYIEKVETSEPVRVYTKVGRRAPLYAGACPRVLLAFMDEVDRERYLEQVELVKIA
KCTVTDKQVLRRLVEEGRNQGYTVSCSELENYSAAVAVPIFNHEGAAVAGLSVAGPEPRFSPDDVVRIVPLLKQAAMDIS
RELGFQGKG

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=245, Percent_Identity=33.469387755102, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1786468, Length=246, Percent_Identity=28.4552845528455, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786715, Length=227, Percent_Identity=29.9559471365639, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1790752, Length=227, Percent_Identity=23.3480176211454, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789999, Length=217, Percent_Identity=26.7281105990783, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87082359, Length=228, Percent_Identity=21.4912280701754, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788581, Length=238, Percent_Identity=24.7899159663866, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27873; Mature: 27873

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTVLKTKELLDLFLDCERLTLPEMVARLRMPKTSVYRMAQSLVALGFLQKQGDQYELG
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHH
LSLLTFGALVAERLDIRRVALPVMERLKEETKEAVNLVIRDGDEALYIEKVETSEPVRVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCCCHHHH
TKVGRRAPLYAGACPRVLLAFMDEVDRERYLEQVELVKIAKCTVTDKQVLRRLVEEGRNQ
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
GYTVSCSELENYSAAVAVPIFNHEGAAVAGLSVAGPEPRFSPDDVVRIVPLLKQAAMDIS
CEEEEHHHHCCCCCEEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RELGFQGKG
HHCCCCCCC
>Mature Secondary Structure
MNKTVLKTKELLDLFLDCERLTLPEMVARLRMPKTSVYRMAQSLVALGFLQKQGDQYELG
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHH
LSLLTFGALVAERLDIRRVALPVMERLKEETKEAVNLVIRDGDEALYIEKVETSEPVRVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCCCHHHH
TKVGRRAPLYAGACPRVLLAFMDEVDRERYLEQVELVKIAKCTVTDKQVLRRLVEEGRNQ
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
GYTVSCSELENYSAAVAVPIFNHEGAAVAGLSVAGPEPRFSPDDVVRIVPLLKQAAMDIS
CEEEEHHHHCCCCCEEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RELGFQGKG
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]