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The map label for this gene is gpmB [H]

Identifier: 138894988

GI number: 138894988

Start: 1412353

End: 1412979

Strand: Direct

Name: gpmB [H]

Synonym: GTNG_1326

Alternate gene names: 138894988

Gene position: 1412353-1412979 (Clockwise)

Preceding gene: 138894987

Following gene: 138894992

Centisome position: 39.78

GC content: 52.47

Gene sequence:

>627_bases
ATGACGACAACGCTGTATTTAACAAGACATGGGGAAACGCAGTGGAACGTGGAAAAGCGGATGCAAGGATGGCAAGACTC
GCCGCTTACCGAAAAAGGGCGGCAAGACGCCAAACGGCTTGGGCAACGGCTTGAAGCGGTCGAGTTGACAGCGATTTATG
CGAGCACGAGCGGTCGGGCGTTCGAAACAGCGGAACTCGTCCGTGGTGAGCGGCCCATTCCGATTTATCAAGACGAGCAG
TTGCGTGAAATGCATCTTGGCGACTGGGAAGGAAAGACGCATGATGAAATTCAGCAAATGGATCCGGTTTTGTTCGACCA
TTTTTGGAACGCCCCCCATTTGTATGTGCCACAGCGCGGTGAACGATTTTGGGACGTGCAACAGCGGGCGCTTGAAGCGG
TGCAGCGCATCATTGCGCGGCATCAAGGGAAGACGGTCTTGGTCGTCACTCACGGTGTCGTGCTGAAAACGCTCATAGCG
GCATTCAAAGGTGTGCCGCTCGATGATCTTTGGGCGCCTCCGTATATGTACGGCACGAGCGTGACAATCGTTGAGGCGCA
TCATGATGAATTTCGTGTTATCGTTGAAGGTGACGCTTCTCATATCAAAGAAATAAAAAAAGTATAG

Upstream 100 bases:

>100_bases
GGGTGCTTTTGGGCTTAAGAGTATGGAGGCAAAACCGTATGCCGAATTACTCGCTTCTTCATATGTAATTGAAATGATGA
ATAGAGGGACGGAGAGAAGG

Downstream 100 bases:

>100_bases
ACACATAGCTAGCCCCGCTTCCCGTGATTGGAAGCGGGGCTTTGCTGTTTGCAAGATCGTGCGGGAACGCCTCTGTCCCT
AAAAATAGAGGGAGCGAACG

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: PGAM; Phosphoglyceromutase [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MTTTLYLTRHGETQWNVEKRMQGWQDSPLTEKGRQDAKRLGQRLEAVELTAIYASTSGRAFETAELVRGERPIPIYQDEQ
LREMHLGDWEGKTHDEIQQMDPVLFDHFWNAPHLYVPQRGERFWDVQQRALEAVQRIIARHQGKTVLVVTHGVVLKTLIA
AFKGVPLDDLWAPPYMYGTSVTIVEAHHDEFRVIVEGDASHIKEIKKV

Sequences:

>Translated_208_residues
MTTTLYLTRHGETQWNVEKRMQGWQDSPLTEKGRQDAKRLGQRLEAVELTAIYASTSGRAFETAELVRGERPIPIYQDEQ
LREMHLGDWEGKTHDEIQQMDPVLFDHFWNAPHLYVPQRGERFWDVQQRALEAVQRIIARHQGKTVLVVTHGVVLKTLIA
AFKGVPLDDLWAPPYMYGTSVTIVEAHHDEFRVIVEGDASHIKEIKKV
>Mature_207_residues
TTTLYLTRHGETQWNVEKRMQGWQDSPLTEKGRQDAKRLGQRLEAVELTAIYASTSGRAFETAELVRGERPIPIYQDEQL
REMHLGDWEGKTHDEIQQMDPVLFDHFWNAPHLYVPQRGERFWDVQQRALEAVQRIIARHQGKTVLVVTHGVVLKTLIAA
FKGVPLDDLWAPPYMYGTSVTIVEAHHDEFRVIVEGDASHIKEIKKV

Specific function: Converts N1-(5-Phospho-Alpha-D-Ribosyl)-5,6- Dimethylbenzimidazole Into N1-Alpha-D-Ribosyl-5,6- Dimethylbenzimidazole; Involved In The Assembly Of The Nucleotide Loop Of Cobalamin. [C]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

Organism=Homo sapiens, GI64762445, Length=175, Percent_Identity=33.7142857142857, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI64762406, Length=175, Percent_Identity=33.7142857142857, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI118582286, Length=175, Percent_Identity=32, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4758902, Length=161, Percent_Identity=32.2981366459627, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI4758900, Length=161, Percent_Identity=32.2981366459627, Blast_Score=64, Evalue=9e-11,
Organism=Homo sapiens, GI224282149, Length=161, Percent_Identity=32.2981366459627, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1786857, Length=167, Percent_Identity=34.1317365269461, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1790856, Length=206, Percent_Identity=31.5533980582524, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI25145314, Length=178, Percent_Identity=34.2696629213483, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6322306, Length=218, Percent_Identity=31.651376146789, Blast_Score=79, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322697, Length=198, Percent_Identity=28.2828282828283, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR023086 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 24021; Mature: 23889

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTLYLTRHGETQWNVEKRMQGWQDSPLTEKGRQDAKRLGQRLEAVELTAIYASTSGRA
CCEEEEEEECCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCC
FETAELVRGERPIPIYQDEQLREMHLGDWEGKTHDEIQQMDPVLFDHFWNAPHLYVPQRG
HHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHCCCCEEECCCCC
ERFWDVQQRALEAVQRIIARHQGKTVLVVTHGVVLKTLIAAFKGVPLDDLWAPPYMYGTS
CHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCCHHHCCCCEECCCE
VTIVEAHHDEFRVIVEGDASHIKEIKKV
EEEEEECCCCEEEEEECCHHHHHHHHCC
>Mature Secondary Structure 
TTTLYLTRHGETQWNVEKRMQGWQDSPLTEKGRQDAKRLGQRLEAVELTAIYASTSGRA
CEEEEEEECCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCC
FETAELVRGERPIPIYQDEQLREMHLGDWEGKTHDEIQQMDPVLFDHFWNAPHLYVPQRG
HHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHCCCCEEECCCCC
ERFWDVQQRALEAVQRIIARHQGKTVLVVTHGVVLKTLIAAFKGVPLDDLWAPPYMYGTS
CHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCCHHHCCCCEECCCE
VTIVEAHHDEFRVIVEGDASHIKEIKKV
EEEEEECCCCEEEEEECCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA