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The map label for this gene is czrA [H]

Identifier: 138894928

GI number: 138894928

Start: 1336071

End: 1336385

Strand: Direct

Name: czrA [H]

Synonym: GTNG_1266

Alternate gene names: 138894928

Gene position: 1336071-1336385 (Clockwise)

Preceding gene: 138894927

Following gene: 138894929

Centisome position: 37.63

GC content: 48.89

Gene sequence:

>315_bases
ATGGCAGTGAAAACGGAAGATCATCTGTTTTTAGAAGCGGAAACAGTCGATGAAGTGTCGCGTCTATTTAAAGCATTAGC
GGATCCGACTCGGATTAAAATGTTGTATTTGTTATCGCAGGAAGAGTGTCATGTCGGCCATATCGCGGAAGTGCTCGGCA
TGTCGCAATCGGCCGTTTCCCACCAGTTGGCGTTGCTTCGGACGTTGCGGCTCGTCAAATACCGCCGCGAAGGGAAGACA
TTGGTGTATTCTTGCGATGATGACCATGTGATTTCGTTGTTAAAGCAGGCGATTGACCATGCACAACACCGGTGA

Upstream 100 bases:

>100_bases
GCTTTTTTTCATGGTCCATCATTGACAAAGAGCACAAATGAGGCATATAATGCATATATATGAACATATGCTCATATATT
AATTTGTGTGGAGCGAGGGA

Downstream 100 bases:

>100_bases
GGGGGAGTCGATTTATGCACCACCATGCGCACGGCCATTGCGACCATCATCATGGCCATCATCACCATGGCAGAGAAGGA
AATCGAAAAGGGTTAGCGAT

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 104; Mature: 103

Protein sequence:

>104_residues
MAVKTEDHLFLEAETVDEVSRLFKALADPTRIKMLYLLSQEECHVGHIAEVLGMSQSAVSHQLALLRTLRLVKYRREGKT
LVYSCDDDHVISLLKQAIDHAQHR

Sequences:

>Translated_104_residues
MAVKTEDHLFLEAETVDEVSRLFKALADPTRIKMLYLLSQEECHVGHIAEVLGMSQSAVSHQLALLRTLRLVKYRREGKT
LVYSCDDDHVISLLKQAIDHAQHR
>Mature_103_residues
AVKTEDHLFLEAETVDEVSRLFKALADPTRIKMLYLLSQEECHVGHIAEVLGMSQSAVSHQLALLRTLRLVKYRREGKTL
VYSCDDDHVISLLKQAIDHAQHR

Specific function: Metal-responsive transcriptional regulator that represses transcription of cadA and the czcD-trkA operon by binding specifically to their promoter. Binding of zinc causes the repressor to dissociate from the DNA [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 11882; Mature: 11751

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKTEDHLFLEAETVDEVSRLFKALADPTRIKMLYLLSQEECHVGHIAEVLGMSQSAVS
CCCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHEECCCCCCHHHHHHHHCCCHHHHH
HQLALLRTLRLVKYRREGKTLVYSCDDDHVISLLKQAIDHAQHR
HHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AVKTEDHLFLEAETVDEVSRLFKALADPTRIKMLYLLSQEECHVGHIAEVLGMSQSAVS
CCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHEECCCCCCHHHHHHHHCCCHHHHH
HQLALLRTLRLVKYRREGKTLVYSCDDDHVISLLKQAIDHAQHR
HHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]