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The map label for this gene is dapG [H]

Identifier: 138894796

GI number: 138894796

Start: 1192648

End: 1193895

Strand: Direct

Name: dapG [H]

Synonym: GTNG_1130

Alternate gene names: 138894796

Gene position: 1192648-1193895 (Clockwise)

Preceding gene: 138894795

Following gene: 138894797

Centisome position: 33.59

GC content: 53.85

Gene sequence:

>1248_bases
ATGAAAATCATTGTCCAAAAGTTTGGCGGCACGTCCGTCCGCGATGAGCGCGGACGGAACTTGGCACGCCGCCATATTGA
AAAGGCGCTTGAAGACGGCTACAAAGTCGTCGTTGTCGTCTCGGCCATGGGCCGTAATGGCGATCCGTACGCGACCGATA
CGCTTCTTCACTTGATCGGCGGCACCGGCCATCATGTGACCAAGCGCGAACAAGATATGTTAATGGCGTGCGGGGAAATC
ATTTCGAGCGTCGTATTTAGCAATTTGCTGAATGAACACGGCATTAAGGCGACGGCGTTTACCGGCGCGCAAGCCGGATT
CCGCACGAACGGCGATCATACGAATGCGAAGATTCTCGAAATGCGCTGCGATCGCCTTCTTGAGGCGCTCGAACAATACG
ATGTCATCGTCGTCGCCGGTTTTCAAGGGGTGGCAGAAAACGGCGATATCACAACGCTTGGCCGCGGTGGAAGCGATACA
TCCGCTGCAGCGCTCGGCGCTGCCTTAAATGCCGAGTGGGTCGACATTTTTACCGATGTCGACGGCGTTATGACCGCCGA
CCCGCGAATTGTCGAAAGTGCCCGGCCACTGGAAGTCGTCACATACACGGAAATTTGCAATATGGCGTACCAAGGAGCGA
AAGTCATTCATCCGCGCGCAGTGGAAATCGCTATGCAAGCGAAAGTGCCGTTGCGCGTTCGTTCGACGTATTCCGATGCG
CCTGGAACGCTTGTCACTTCATCGGTTCGTGGTCAAAAAGGAAGTGATGTGAAGGAGCGGCTTGTCACGGGCATTGCATA
TGTCGCCAATGTCACGCAAATTAAAGTGCTGGCGAAAGAGGGACACTATGAACTGCAGTCTGATGTGTTCCAAGCGATGG
CTCGCGAAGGGATCAGCGTCGACTTTATTAACATTTCGCCATACGGCGTCGTTTACACAGTGAGCGGCGACATGACAGAA
AAAGCGATTGCTGCTTTGCGTCGTGTTGGTTATGAGCCGGCGGTGACGCCTCGCTGTGCCAAAGTGTCGGTTGTCGGTGC
TGGCATTGCTGGCGTGCCGGGGGTGACGGCGAAAATCGTCACTGCTTTATCGGAACAAGGCATTCAAATTTTGCAGTCGG
CTGACAGCCATACGACGATTTGGGTGCTTGTGAAACAGGATGATATGGAAAAAGCGGTTAACGCCTTGCATGACGCCTTT
TGTCTGTCTGAGGAAGGCGGATATGAAGCGATTTGGAACGAGGAGTGA

Upstream 100 bases:

>100_bases
TTGCTGACAATCTATTAAAAGGAGCAGCCTCAAACTCCGTACAAATTGCAGAAAGCTTATTGAAGCTTGGGCTGATTTGA
ATAAGCATCGGGGTGTTAGC

Downstream 100 bases:

>100_bases
AAACAGTGGCTCAGTTCGGAAACATTGTAACGGCGATGGTGACACCATTTGACCGGAAAGGAAATCTCGATTTAGCGAAA
ACGACGGAGCTCGTCAACTA

Product: aspartate kinase I

Products: NA

Alternate protein names: Aspartate kinase 1; Aspartokinase I [H]

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MKIIVQKFGGTSVRDERGRNLARRHIEKALEDGYKVVVVVSAMGRNGDPYATDTLLHLIGGTGHHVTKREQDMLMACGEI
ISSVVFSNLLNEHGIKATAFTGAQAGFRTNGDHTNAKILEMRCDRLLEALEQYDVIVVAGFQGVAENGDITTLGRGGSDT
SAAALGAALNAEWVDIFTDVDGVMTADPRIVESARPLEVVTYTEICNMAYQGAKVIHPRAVEIAMQAKVPLRVRSTYSDA
PGTLVTSSVRGQKGSDVKERLVTGIAYVANVTQIKVLAKEGHYELQSDVFQAMAREGISVDFINISPYGVVYTVSGDMTE
KAIAALRRVGYEPAVTPRCAKVSVVGAGIAGVPGVTAKIVTALSEQGIQILQSADSHTTIWVLVKQDDMEKAVNALHDAF
CLSEEGGYEAIWNEE

Sequences:

>Translated_415_residues
MKIIVQKFGGTSVRDERGRNLARRHIEKALEDGYKVVVVVSAMGRNGDPYATDTLLHLIGGTGHHVTKREQDMLMACGEI
ISSVVFSNLLNEHGIKATAFTGAQAGFRTNGDHTNAKILEMRCDRLLEALEQYDVIVVAGFQGVAENGDITTLGRGGSDT
SAAALGAALNAEWVDIFTDVDGVMTADPRIVESARPLEVVTYTEICNMAYQGAKVIHPRAVEIAMQAKVPLRVRSTYSDA
PGTLVTSSVRGQKGSDVKERLVTGIAYVANVTQIKVLAKEGHYELQSDVFQAMAREGISVDFINISPYGVVYTVSGDMTE
KAIAALRRVGYEPAVTPRCAKVSVVGAGIAGVPGVTAKIVTALSEQGIQILQSADSHTTIWVLVKQDDMEKAVNALHDAF
CLSEEGGYEAIWNEE
>Mature_415_residues
MKIIVQKFGGTSVRDERGRNLARRHIEKALEDGYKVVVVVSAMGRNGDPYATDTLLHLIGGTGHHVTKREQDMLMACGEI
ISSVVFSNLLNEHGIKATAFTGAQAGFRTNGDHTNAKILEMRCDRLLEALEQYDVIVVAGFQGVAENGDITTLGRGGSDT
SAAALGAALNAEWVDIFTDVDGVMTADPRIVESARPLEVVTYTEICNMAYQGAKVIHPRAVEIAMQAKVPLRVRSTYSDA
PGTLVTSSVRGQKGSDVKERLVTGIAYVANVTQIKVLAKEGHYELQSDVFQAMAREGISVDFINISPYGVVYTVSGDMTE
KAIAALRRVGYEPAVTPRCAKVSVVGAGIAGVPGVTAKIVTALSEQGIQILQSADSHTTIWVLVKQDDMEKAVNALHDAF
CLSEEGGYEAIWNEE

Specific function: Catalyzes 2 nonconsecutive reactions in the common biosynthetic pathway leading from Asp to diaminopimelate and Lys, to Met, and to Thr and Ile. [C]

COG id: COG0527

COG function: function code E; Aspartokinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartokinase family [H]

Homologues:

Organism=Escherichia coli, GI1786183, Length=279, Percent_Identity=36.9175627240143, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1790455, Length=408, Percent_Identity=28.921568627451, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790376, Length=337, Percent_Identity=25.5192878338279, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320893, Length=376, Percent_Identity=27.3936170212766, Blast_Score=114, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR005260
- InterPro:   IPR001341
- InterPro:   IPR018042 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.4 [H]

Molecular weight: Translated: 44583; Mature: 44583

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00324 ASPARTOKINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIVQKFGGTSVRDERGRNLARRHIEKALEDGYKVVVVVSAMGRNGDPYATDTLLHLIG
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHC
GTGHHVTKREQDMLMACGEIISSVVFSNLLNEHGIKATAFTGAQAGFRTNGDHTNAKILE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHH
MRCDRLLEALEQYDVIVVAGFQGVAENGDITTLGRGGSDTSAAALGAALNAEWVDIFTDV
HHHHHHHHHHHHCCEEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCHHEEEECC
DGVMTADPRIVESARPLEVVTYTEICNMAYQGAKVIHPRAVEIAMQAKVPLRVRSTYSDA
CCEEECCCHHHCCCCCEEEEEHHHHHHHHHCCCEEECCHHEEEEEECCCCEEEECCCCCC
PGTLVTSSVRGQKGSDVKERLVTGIAYVANVTQIKVLAKEGHYELQSDVFQAMAREGISV
CCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHCCCEE
DFINISPYGVVYTVSGDMTEKAIAALRRVGYEPAVTPRCAKVSVVGAGIAGVPGVTAKIV
EEEEECCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHH
TALSEQGIQILQSADSHTTIWVLVKQDDMEKAVNALHDAFCLSEEGGYEAIWNEE
HHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MKIIVQKFGGTSVRDERGRNLARRHIEKALEDGYKVVVVVSAMGRNGDPYATDTLLHLIG
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHC
GTGHHVTKREQDMLMACGEIISSVVFSNLLNEHGIKATAFTGAQAGFRTNGDHTNAKILE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHH
MRCDRLLEALEQYDVIVVAGFQGVAENGDITTLGRGGSDTSAAALGAALNAEWVDIFTDV
HHHHHHHHHHHHCCEEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCHHEEEECC
DGVMTADPRIVESARPLEVVTYTEICNMAYQGAKVIHPRAVEIAMQAKVPLRVRSTYSDA
CCEEECCCHHHCCCCCEEEEEHHHHHHHHHCCCEEECCHHEEEEEECCCCEEEECCCCCC
PGTLVTSSVRGQKGSDVKERLVTGIAYVANVTQIKVLAKEGHYELQSDVFQAMAREGISV
CCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHCCCEE
DFINISPYGVVYTVSGDMTEKAIAALRRVGYEPAVTPRCAKVSVVGAGIAGVPGVTAKIV
EEEEECCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHH
TALSEQGIQILQSADSHTTIWVLVKQDDMEKAVNALHDAFCLSEEGGYEAIWNEE
HHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377 [H]