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The map label for this gene is asd [H]

Identifier: 138894795

GI number: 138894795

Start: 1191584

End: 1192627

Strand: Direct

Name: asd [H]

Synonym: GTNG_1129

Alternate gene names: 138894795

Gene position: 1191584-1192627 (Clockwise)

Preceding gene: 138894794

Following gene: 138894796

Centisome position: 33.56

GC content: 51.44

Gene sequence:

>1044_bases
ATGACTCAAAAACAATATCATGTTGCTGTTGTCGGAGCAACGGGGGCAGTTGGGCAACAAATGGTGCGGACGCTTGAAGA
CCGGAACTTTCCGGTCGGAAAATTAACGCTGTTATCATCGGAACGTTCGGCAGGCAAAAAAATGCGCTTCCGCGGCGAGG
AAATTGAGGTGCAAGTGGCAACACCGGAGCGTTTCGACGGGGTGGATATCGCCTTATTCAGCGCCGGCGGGTCAGTATCG
AAAGCATTGGCGCCGGAAGCGGTTCGGCGTGGGGCGATCGTTATCGACAATACGAGCGCATTTCGGATGGACGAAAAGGT
GCCGCTTGTCGTCCCAGAAGTAAATGAAAGCGACTTGACATGGCATAACGGCATCATTGCCAATCCGAACTGCTCGACGA
TTCAAATGGTCGTGGCGCTAGAGCCGATCCGGAAAGCGTTCGGCTTAGAGCGCGTCATTGTCTCGACGTACCAAGCTGTT
TCTGGGGCTGGAGCGCAGGCTATCGAGGAGTTGCATGCACAGACGAAAGCCGTGCTCGAAAATAAGCCGGTTGAAGCTAA
TATTTTGCCAGTGAAATCGGATCGGAAACATTACCAAATTGCATTCAACGCCATTCCGCAAATCGATAAATTTCAAGACA
ATGGCTTTACATTTGAAGAGATGAAAATGATTAATGAAACGAAAAAAATTATGCATATGCCTGAGCTAAAAGTCGCAGCA
ACGTGCGTACGCATCCCGGTGGCGAGCGGCCACTCGGAATCGGTGTACGTCGAAATCGAACAAGACGGCGTCACCGCTGC
CGATCTGCAGTCGGTACTGAGCGAGGCACCGGGCGTCGTGTTGCAAGATGACCCGAACGAGCAGTTGTATCCGATGCCGG
CGGATTGCGTCGGAAAGTATGACGTCTTTGTCGGCCGCATCCGCCGCGACTTGGACAATAGCCGTGCTTTCCATCTATGG
ATCGTTGCTGACAATCTATTAAAAGGAGCAGCCTCAAACTCCGTACAAATTGCAGAAAGCTTATTGAAGCTTGGGCTGAT
TTGA

Upstream 100 bases:

>100_bases
GCACCGCACTCAAAAATTTTCTCTCGTCCGCAGTGGAATGTGATAAAATAAAAATTATGAATTCACTTTTAACAGTGACG
ATGTGGAAGGAGAATGGCTG

Downstream 100 bases:

>100_bases
ATAAGCATCGGGGTGTTAGCATGAAAATCATTGTCCAAAAGTTTGGCGGCACGTCCGTCCGCGATGAGCGCGGACGGAAC
TTGGCACGCCGCCATATTGA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MTQKQYHVAVVGATGAVGQQMVRTLEDRNFPVGKLTLLSSERSAGKKMRFRGEEIEVQVATPERFDGVDIALFSAGGSVS
KALAPEAVRRGAIVIDNTSAFRMDEKVPLVVPEVNESDLTWHNGIIANPNCSTIQMVVALEPIRKAFGLERVIVSTYQAV
SGAGAQAIEELHAQTKAVLENKPVEANILPVKSDRKHYQIAFNAIPQIDKFQDNGFTFEEMKMINETKKIMHMPELKVAA
TCVRIPVASGHSESVYVEIEQDGVTAADLQSVLSEAPGVVLQDDPNEQLYPMPADCVGKYDVFVGRIRRDLDNSRAFHLW
IVADNLLKGAASNSVQIAESLLKLGLI

Sequences:

>Translated_347_residues
MTQKQYHVAVVGATGAVGQQMVRTLEDRNFPVGKLTLLSSERSAGKKMRFRGEEIEVQVATPERFDGVDIALFSAGGSVS
KALAPEAVRRGAIVIDNTSAFRMDEKVPLVVPEVNESDLTWHNGIIANPNCSTIQMVVALEPIRKAFGLERVIVSTYQAV
SGAGAQAIEELHAQTKAVLENKPVEANILPVKSDRKHYQIAFNAIPQIDKFQDNGFTFEEMKMINETKKIMHMPELKVAA
TCVRIPVASGHSESVYVEIEQDGVTAADLQSVLSEAPGVVLQDDPNEQLYPMPADCVGKYDVFVGRIRRDLDNSRAFHLW
IVADNLLKGAASNSVQIAESLLKLGLI
>Mature_346_residues
TQKQYHVAVVGATGAVGQQMVRTLEDRNFPVGKLTLLSSERSAGKKMRFRGEEIEVQVATPERFDGVDIALFSAGGSVSK
ALAPEAVRRGAIVIDNTSAFRMDEKVPLVVPEVNESDLTWHNGIIANPNCSTIQMVVALEPIRKAFGLERVIVSTYQAVS
GAGAQAIEELHAQTKAVLENKPVEANILPVKSDRKHYQIAFNAIPQIDKFQDNGFTFEEMKMINETKKIMHMPELKVAAT
CVRIPVASGHSESVYVEIEQDGVTAADLQSVLSEAPGVVLQDDPNEQLYPMPADCVGKYDVFVGRIRRDLDNSRAFHLWI
VADNLLKGAASNSVQIAESLLKLGLI

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=341, Percent_Identity=33.7243401759531, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1789841, Length=358, Percent_Identity=27.6536312849162, Blast_Score=92, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6320362, Length=401, Percent_Identity=27.6807980049875, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37937; Mature: 37806

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKQYHVAVVGATGAVGQQMVRTLEDRNFPVGKLTLLSSERSAGKKMRFRGEEIEVQVA
CCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCCEEEEEEE
TPERFDGVDIALFSAGGSVSKALAPEAVRRGAIVIDNTSAFRMDEKVPLVVPEVNESDLT
CCCCCCCCEEEEEECCCCHHHHCCHHHHHCCEEEEECCCCEEECCCCCEEEECCCCCCCE
WHNGIIANPNCSTIQMVVALEPIRKAFGLERVIVSTYQAVSGAGAQAIEELHAQTKAVLE
ECCCEEECCCCCEEEEEEHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
NKPVEANILPVKSDRKHYQIAFNAIPQIDKFQDNGFTFEEMKMINETKKIMHMPELKVAA
CCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHEE
TCVRIPVASGHSESVYVEIEQDGVTAADLQSVLSEAPGVVLQDDPNEQLYPMPADCVGKY
EEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHCCHH
DVFVGRIRRDLDNSRAFHLWIVADNLLKGAASNSVQIAESLLKLGLI
HHHHHHHHHHCCCCCEEEEEEEECHHHHCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQKQYHVAVVGATGAVGQQMVRTLEDRNFPVGKLTLLSSERSAGKKMRFRGEEIEVQVA
CCCEEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCCEEEEEEE
TPERFDGVDIALFSAGGSVSKALAPEAVRRGAIVIDNTSAFRMDEKVPLVVPEVNESDLT
CCCCCCCCEEEEEECCCCHHHHCCHHHHHCCEEEEECCCCEEECCCCCEEEECCCCCCCE
WHNGIIANPNCSTIQMVVALEPIRKAFGLERVIVSTYQAVSGAGAQAIEELHAQTKAVLE
ECCCEEECCCCCEEEEEEHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
NKPVEANILPVKSDRKHYQIAFNAIPQIDKFQDNGFTFEEMKMINETKKIMHMPELKVAA
CCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHEE
TCVRIPVASGHSESVYVEIEQDGVTAADLQSVLSEAPGVVLQDDPNEQLYPMPADCVGKY
EEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHCCHH
DVFVGRIRRDLDNSRAFHLWIVADNLLKGAASNSVQIAESLLKLGLI
HHHHHHHHHHCCCCCEEEEEEEECHHHHCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377; 8345520 [H]