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The map label for this gene is lepB [H]

Identifier: 138894724

GI number: 138894724

Start: 1123220

End: 1123771

Strand: Direct

Name: lepB [H]

Synonym: GTNG_1056

Alternate gene names: 138894724

Gene position: 1123220-1123771 (Clockwise)

Preceding gene: 138894723

Following gene: 138894725

Centisome position: 31.64

GC content: 49.46

Gene sequence:

>552_bases
ATGGAACAGAAGAAAAGCGAATGGCGTGAGTGGTTGAAAGCCATTGTCGTCGCGGTCTTGTTGGCTGGGGGCATCCGCTA
TTTTATTTTCGCCCCGATTATTGTCGACGGCTATTCAATGATGCCAACATTACATAACCATGAGCGGATGATCGTCAATA
AATTGGCCTATAAAATCGGCATGCCAAACCGCTTCGATATTATTGTTTTTCACGCTGAAGAAGGGAGAGACTATATCAAG
CGGGTCATCGGCCTGCCCGGCGACCGGATCGAATATAAAAACGACACACTCTATGTCAACGGCAAGCCGTATGACGAGCC
GTATTTGGACGAATATAAAAAGCAGGTAGCCGACGGGCCGCTGACCGAGCCATTTACGTTAGAGGAGTTGACCGGGCAGA
GCACCGTGCCGGAAGGACATTTGTTCGTCATGGGTGACAATCGCCGTTTCAGCAAAGATAGCCGTCATATCGGTTTCATT
CCGATGGAGAAAGTTGTCGGCAAGGCGAATATTGTCTACTGGCCGCTTGGTGGCGTCCGGATTGCGAAATAA

Upstream 100 bases:

>100_bases
GACATCAGTGGGTCGTAGCGAAAAAGGAGCTTGCTTTCAAGCTCCTTTTTTCACTATCCGTCGGCGAAGCGGGTAAATTA
TGATTTGGGTGGGAGAAAAG

Downstream 100 bases:

>100_bases
ATGAGGCAGGTGATGCCAATGACGATGATTCAATGGTTTCCCGGCCATATGGCGAAAGCGAAGCGGGAAGTACAAGAAAA
ACTAAAACTGATCGATGTGG

Product: Type I signal peptidase

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MEQKKSEWREWLKAIVVAVLLAGGIRYFIFAPIIVDGYSMMPTLHNHERMIVNKLAYKIGMPNRFDIIVFHAEEGRDYIK
RVIGLPGDRIEYKNDTLYVNGKPYDEPYLDEYKKQVADGPLTEPFTLEELTGQSTVPEGHLFVMGDNRRFSKDSRHIGFI
PMEKVVGKANIVYWPLGGVRIAK

Sequences:

>Translated_183_residues
MEQKKSEWREWLKAIVVAVLLAGGIRYFIFAPIIVDGYSMMPTLHNHERMIVNKLAYKIGMPNRFDIIVFHAEEGRDYIK
RVIGLPGDRIEYKNDTLYVNGKPYDEPYLDEYKKQVADGPLTEPFTLEELTGQSTVPEGHLFVMGDNRRFSKDSRHIGFI
PMEKVVGKANIVYWPLGGVRIAK
>Mature_183_residues
MEQKKSEWREWLKAIVVAVLLAGGIRYFIFAPIIVDGYSMMPTLHNHERMIVNKLAYKIGMPNRFDIIVFHAEEGRDYIK
RVIGLPGDRIEYKNDTLYVNGKPYDEPYLDEYKKQVADGPLTEPFTLEELTGQSTVPEGHLFVMGDNRRFSKDSRHIGFI
PMEKVVGKANIVYWPLGGVRIAK

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 21076; Mature: 21076

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQKKSEWREWLKAIVVAVLLAGGIRYFIFAPIIVDGYSMMPTLHNHERMIVNKLAYKIG
CCCHHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHCC
MPNRFDIIVFHAEEGRDYIKRVIGLPGDRIEYKNDTLYVNGKPYDEPYLDEYKKQVADGP
CCCCEEEEEEECCCCHHHHHHHHCCCCCCEEECCCEEEECCCCCCCHHHHHHHHHHCCCC
LTEPFTLEELTGQSTVPEGHLFVMGDNRRFSKDSRHIGFIPMEKVVGKANIVYWPLGGVR
CCCCEEHHHHCCCCCCCCCEEEEEECCCCCCCCCCEECCEEHHHHHCCCCEEEECCCCEE
IAK
ECC
>Mature Secondary Structure
MEQKKSEWREWLKAIVVAVLLAGGIRYFIFAPIIVDGYSMMPTLHNHERMIVNKLAYKIG
CCCHHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHCC
MPNRFDIIVFHAEEGRDYIKRVIGLPGDRIEYKNDTLYVNGKPYDEPYLDEYKKQVADGP
CCCCEEEEEEECCCCHHHHHHHHCCCCCCEEECCCEEEECCCCCCCHHHHHHHHHHCCCC
LTEPFTLEELTGQSTVPEGHLFVMGDNRRFSKDSRHIGFIPMEKVVGKANIVYWPLGGVR
CCCCEEHHHHCCCCCCCCCEEEEEECCCCCCCCCCEECCEEHHHHHCCCCEEEECCCCEE
IAK
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8801417 [H]