Click here to switch to the map view.

The map label for this gene is fmt [H]

Identifier: 138894693

GI number: 138894693

Start: 1094075

End: 1095034

Strand: Direct

Name: fmt [H]

Synonym: GTNG_1025

Alternate gene names: 138894693

Gene position: 1094075-1095034 (Clockwise)

Preceding gene: 138894692

Following gene: 138894694

Centisome position: 30.82

GC content: 53.85

Gene sequence:

>960_bases
ATGACGAACATTGTCTTTATGGGAACGCCTGATTTTGCGGTGCCGGTTTTACGGCAGCTGCTTGATGACGGGTATCGGGT
TGTTGCCGTTGTTACGCAGCCGGACAAGCCGAAAGGGCGAAAGCGCGAGCTTGTTCCGCCCCCCGTTAAGGTCGAGGCGC
AAAAACACGGCATCCCGGTATTGCAACCGACGAAAATTCGTGAACCGGAACAATACGAACAAGTGCTGGCGTTTGCGCCT
GACTTGATCGTGACCGCGGCATTTGGACAAATTTTGCCTAAGGCTCTGCTTGACGCTCCCAAATACGGCTGCATTAATGT
TCACGCCTCGCTTCTTCCCGAGCTGCGCGGCGGTGCGCCGATCCATTATGCCATTTGGCAAGGGAAAACGAAAACAGGTG
TCACGATTATGTATATGGCGGAAAAGTTGGATGCCGGCGACATGTTGACGCAAGTCGAAGTGCCGATTGAAGAAACCGAT
ACCGTCGGCACACTGCATGATAAATTGAGCGCTGCCGGGGCTAAACTATTATCAGAAACGCTCCCGCTTTTATTGGAAGG
TAACCTTGCGCCTATTCCGCAAGAGGAAGAGAAAGCGACATATGCTCCGAATATCCGGCGTGAACAAGAGCGGATTGACT
GGGCGCAGCCTGGTGAGGCGATTTACAACCATATCCGTGCTTTTCATCCGTGGCCGGTTACGTATACGACATACGACGGG
AACGTTTGGAAAATCTGGTGGGGCGAAAAAGTGCCGGCGCCAAGCTTAGCATCGCCAGGCACGATTTTATCGCTTGAGGA
AGACGGCATCGTCGTCGCCACCGGCAGTGAGACGGCCATTAAAATTACTGAATTGCAGCCGGCCGGCAAAAAGCGAATGG
CCGCCAGCGAGTTTTTGCGCGGTGCTGGCAGCCGGCTTGCGGTCGGCACGAAGCTAGGAGAGAACAATGAACGTACGTGA

Upstream 100 bases:

>100_bases
GCGCGCCTTGCAGCACGAAATCGATCACTTGCACGGCGTGTTGTTTACATCGAAAGTGATCCGTTACTGCGATCTTGAAG
AATTGGAAGGGTAGATGCTG

Downstream 100 bases:

>100_bases
ACTTGCTTTAGACACGCTGTTGGCCATCGAACAAAAAGGGGCTTACAGCCATTTGCAACTGAACAACGCCATTCAAAAAG
GGCGTCTTGACGGGCGCGAT

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MTNIVFMGTPDFAVPVLRQLLDDGYRVVAVVTQPDKPKGRKRELVPPPVKVEAQKHGIPVLQPTKIREPEQYEQVLAFAP
DLIVTAAFGQILPKALLDAPKYGCINVHASLLPELRGGAPIHYAIWQGKTKTGVTIMYMAEKLDAGDMLTQVEVPIEETD
TVGTLHDKLSAAGAKLLSETLPLLLEGNLAPIPQEEEKATYAPNIRREQERIDWAQPGEAIYNHIRAFHPWPVTYTTYDG
NVWKIWWGEKVPAPSLASPGTILSLEEDGIVVATGSETAIKITELQPAGKKRMAASEFLRGAGSRLAVGTKLGENNERT

Sequences:

>Translated_319_residues
MTNIVFMGTPDFAVPVLRQLLDDGYRVVAVVTQPDKPKGRKRELVPPPVKVEAQKHGIPVLQPTKIREPEQYEQVLAFAP
DLIVTAAFGQILPKALLDAPKYGCINVHASLLPELRGGAPIHYAIWQGKTKTGVTIMYMAEKLDAGDMLTQVEVPIEETD
TVGTLHDKLSAAGAKLLSETLPLLLEGNLAPIPQEEEKATYAPNIRREQERIDWAQPGEAIYNHIRAFHPWPVTYTTYDG
NVWKIWWGEKVPAPSLASPGTILSLEEDGIVVATGSETAIKITELQPAGKKRMAASEFLRGAGSRLAVGTKLGENNERT
>Mature_318_residues
TNIVFMGTPDFAVPVLRQLLDDGYRVVAVVTQPDKPKGRKRELVPPPVKVEAQKHGIPVLQPTKIREPEQYEQVLAFAPD
LIVTAAFGQILPKALLDAPKYGCINVHASLLPELRGGAPIHYAIWQGKTKTGVTIMYMAEKLDAGDMLTQVEVPIEETDT
VGTLHDKLSAAGAKLLSETLPLLLEGNLAPIPQEEEKATYAPNIRREQERIDWAQPGEAIYNHIRAFHPWPVTYTTYDGN
VWKIWWGEKVPAPSLASPGTILSLEEDGIVVATGSETAIKITELQPAGKKRMAASEFLRGAGSRLAVGTKLGENNERT

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI21614513, Length=320, Percent_Identity=30.3125, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI238814322, Length=312, Percent_Identity=28.8461538461538, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI164663775, Length=318, Percent_Identity=30.188679245283, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI4503915, Length=145, Percent_Identity=30.3448275862069, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI209869995, Length=145, Percent_Identity=30.3448275862069, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI209869993, Length=145, Percent_Identity=30.3448275862069, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789683, Length=309, Percent_Identity=44.9838187702265, Blast_Score=268, Evalue=3e-73,
Organism=Escherichia coli, GI1788589, Length=314, Percent_Identity=29.2993630573248, Blast_Score=149, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI133930964, Length=323, Percent_Identity=30.030959752322, Blast_Score=126, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6319458, Length=276, Percent_Identity=28.6231884057971, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45550868, Length=305, Percent_Identity=31.4754098360656, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI28571984, Length=228, Percent_Identity=32.8947368421053, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24585660, Length=319, Percent_Identity=26.6457680250784, Blast_Score=94, Evalue=9e-20,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 34965; Mature: 34833

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNIVFMGTPDFAVPVLRQLLDDGYRVVAVVTQPDKPKGRKRELVPPPVKVEAQKHGIPV
CCCEEEEECCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEHHHCCCCC
LQPTKIREPEQYEQVLAFAPDLIVTAAFGQILPKALLDAPKYGCINVHASLLPELRGGAP
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCC
IHYAIWQGKTKTGVTIMYMAEKLDAGDMLTQVEVPIEETDTVGTLHDKLSAAGAKLLSET
EEEEEECCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
LPLLLEGNLAPIPQEEEKATYAPNIRREQERIDWAQPGEAIYNHIRAFHPWPVTYTTYDG
CCEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEECC
NVWKIWWGEKVPAPSLASPGTILSLEEDGIVVATGSETAIKITELQPAGKKRMAASEFLR
CEEEEEECCCCCCCCCCCCCEEEEECCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHH
GAGSRLAVGTKLGENNERT
CCCCEEEEEEECCCCCCCC
>Mature Secondary Structure 
TNIVFMGTPDFAVPVLRQLLDDGYRVVAVVTQPDKPKGRKRELVPPPVKVEAQKHGIPV
CCEEEEECCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEHHHCCCCC
LQPTKIREPEQYEQVLAFAPDLIVTAAFGQILPKALLDAPKYGCINVHASLLPELRGGAP
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCC
IHYAIWQGKTKTGVTIMYMAEKLDAGDMLTQVEVPIEETDTVGTLHDKLSAAGAKLLSET
EEEEEECCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
LPLLLEGNLAPIPQEEEKATYAPNIRREQERIDWAQPGEAIYNHIRAFHPWPVTYTTYDG
CCEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEECC
NVWKIWWGEKVPAPSLASPGTILSLEEDGIVVATGSETAIKITELQPAGKKRMAASEFLR
CEEEEEECCCCCCCCCCCCCEEEEECCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHH
GAGSRLAVGTKLGENNERT
CCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA