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The map label for this gene is pyrDII

Identifier: 138894680

GI number: 138894680

Start: 1078332

End: 1079105

Strand: Direct

Name: pyrDII

Synonym: GTNG_1010

Alternate gene names: 138894680

Gene position: 1078332-1079105 (Clockwise)

Preceding gene: 138894679

Following gene: 138894681

Centisome position: 30.37

GC content: 58.27

Gene sequence:

>774_bases
ATGATCGGCCGTGAACGAATGACGGTAGTCAGCCAACGGATGATTGCTGAGCGCACGTATGAATTGACACTGAGCGGCCA
ACTCGTTGCCCAAATGAATGAGCCGGGACAGTTCGTTCATATCAAAGTGGCAGAAGCGGCCGATCCGCTTTTGCGCCGTC
CGTTGAGCCTTTGTCAGATCGACCACAAGCAGGGGCAATGCATCATCATTTACCGCCAGGAAGGGAAAGGCACTGCGTTG
TTAACACAAAAACAGCCGGGCGACAGAGTTGATGTGCTCGGTCCGCTCGGCCACGGCTTTCCGCTAGATGCCGCGCCAGC
GGGCGGTCGGGCGCTGTTGGTTGGCGGCGGCATCGGCGTCCCGCCACTGTACGAATTGGCAAAACAGCTGGCGAACCGGG
GGGTAAACGTCGTGAGCGTACTTGGCTTCGCGACCAAAGCCGCCGTTTTTTACGAAGCGGAATTTGCTGCGTTCGGTGAG
ACGTATATCGCCACCGATGACGGATCATACGGGATGGCAGGGCGCGTCACTGATGTGATCGAGCAACAGGGCCTTTCGTT
TGACGTGTTGTACGCCTGCGGCCCGAAGCCGATGTTAAAGGCGTTGGATGAACGATTCCGCGGCCGACCGGTCTATTTGT
CGCTAGAGGAGCGGATGGGTTGCGGCGTCGGAGCGTGTTTTGCCTGCGTCTGCCATGTGCCGGGGAGCGAGACGGCGTAT
AAAAAAGTATGCAGCGACGGTCCGGTATTTCGGGCCGGGGAGGTGGTGTTATGA

Upstream 100 bases:

>100_bases
TTCCGTGCTTGACGTCGTTGGATACCGCACGTGCGATGCTCCAGGTCGTTGAATCGATGACGTTTTCAACGACGGCGATG
ACGGAAGGGCTGGTGCGTTC

Downstream 100 bases:

>100_bases
ACCGGCTTGCGGTCGAACTGCCAGGTCTTTCGCTCAAAAACCCGATCATGCCGGCGTCCGGATGTTTCGGGTTTGGCCGC
GAGTACGCCCAGTTTTACGA

Product: dihydroorotate dehydrogenase electron transfer subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MIGRERMTVVSQRMIAERTYELTLSGQLVAQMNEPGQFVHIKVAEAADPLLRRPLSLCQIDHKQGQCIIIYRQEGKGTAL
LTQKQPGDRVDVLGPLGHGFPLDAAPAGGRALLVGGGIGVPPLYELAKQLANRGVNVVSVLGFATKAAVFYEAEFAAFGE
TYIATDDGSYGMAGRVTDVIEQQGLSFDVLYACGPKPMLKALDERFRGRPVYLSLEERMGCGVGACFACVCHVPGSETAY
KKVCSDGPVFRAGEVVL

Sequences:

>Translated_257_residues
MIGRERMTVVSQRMIAERTYELTLSGQLVAQMNEPGQFVHIKVAEAADPLLRRPLSLCQIDHKQGQCIIIYRQEGKGTAL
LTQKQPGDRVDVLGPLGHGFPLDAAPAGGRALLVGGGIGVPPLYELAKQLANRGVNVVSVLGFATKAAVFYEAEFAAFGE
TYIATDDGSYGMAGRVTDVIEQQGLSFDVLYACGPKPMLKALDERFRGRPVYLSLEERMGCGVGACFACVCHVPGSETAY
KKVCSDGPVFRAGEVVL
>Mature_257_residues
MIGRERMTVVSQRMIAERTYELTLSGQLVAQMNEPGQFVHIKVAEAADPLLRRPLSLCQIDHKQGQCIIIYRQEGKGTAL
LTQKQPGDRVDVLGPLGHGFPLDAAPAGGRALLVGGGIGVPPLYELAKQLANRGVNVVSVLGFATKAAVFYEAEFAAFGE
TYIATDDGSYGMAGRVTDVIEQQGLSFDVLYACGPKPMLKALDERFRGRPVYLSLEERMGCGVGACFACVCHVPGSETAY
KKVCSDGPVFRAGEVVL

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+)

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRK_GEOTN (A4IM34)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001125133.1
- ProteinModelPortal:   A4IM34
- SMR:   A4IM34
- STRING:   A4IM34
- GeneID:   4965953
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_1010
- NMPDR:   fig|420246.5.peg.979
- eggNOG:   COG0543
- HOGENOM:   HBG730970
- OMA:   RPISICS
- ProtClustDB:   PRK00054
- BioCyc:   GTHE420246:GTNG_1010-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01211_B
- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938
- PIRSF:   PIRSF006816

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1; SSF63380 Riboflavin_synthase_like_b-brl

EC number: NA

Molecular weight: Translated: 27581; Mature: 27581

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS51384 FAD_FR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRERMTVVSQRMIAERTYELTLSGQLVAQMNEPGQFVHIKVAEAADPLLRRPLSLCQI
CCCHHHHHHHHHHHHHHHEEEEEECCEEEEEECCCCCEEEEEEHHHCCHHHHCCHHHHHH
DHKQGQCIIIYRQEGKGTALLTQKQPGDRVDVLGPLGHGFPLDAAPAGGRALLVGGGIGV
HCCCCCEEEEEEECCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCEEEEEECCCCC
PPLYELAKQLANRGVNVVSVLGFATKAAVFYEAEFAAFGETYIATDDGSYGMAGRVTDVI
CHHHHHHHHHHHCCCCEEHHHHHHHHHEEEEEEHHHHCCCEEEEECCCCCCCCCHHHHHH
EQQGLSFDVLYACGPKPMLKALDERFRGRPVYLSLEERMGCGVGACFACVCHVPGSETAY
HHCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEHHHCCCCHHHHHHHHCCCCCCHHHH
KKVCSDGPVFRAGEVVL
HHHCCCCCEECCCCEEC
>Mature Secondary Structure
MIGRERMTVVSQRMIAERTYELTLSGQLVAQMNEPGQFVHIKVAEAADPLLRRPLSLCQI
CCCHHHHHHHHHHHHHHHEEEEEECCEEEEEECCCCCEEEEEEHHHCCHHHHCCHHHHHH
DHKQGQCIIIYRQEGKGTALLTQKQPGDRVDVLGPLGHGFPLDAAPAGGRALLVGGGIGV
HCCCCCEEEEEEECCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCEEEEEECCCCC
PPLYELAKQLANRGVNVVSVLGFATKAAVFYEAEFAAFGETYIATDDGSYGMAGRVTDVI
CHHHHHHHHHHHCCCCEEHHHHHHHHHEEEEEEHHHHCCCEEEEECCCCCCCCCHHHHHH
EQQGLSFDVLYACGPKPMLKALDERFRGRPVYLSLEERMGCGVGACFACVCHVPGSETAY
HHCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEHHHCCCCHHHHHHHHCCCCCCHHHH
KKVCSDGPVFRAGEVVL
HHHCCCCCEECCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA