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The map label for this gene is carA [H]

Identifier: 138894346

GI number: 138894346

Start: 751127

End: 752191

Strand: Direct

Name: carA [H]

Synonym: GTNG_0674

Alternate gene names: 138894346

Gene position: 751127-752191 (Clockwise)

Preceding gene: 138894345

Following gene: 138894347

Centisome position: 21.16

GC content: 50.89

Gene sequence:

>1065_bases
ATGAAAGCGTATTTGCATCTGGCCAGTGGAAAAACGTTCAGCGGTAAGCTTGCCACCCCGCTTGAAAAAAAGGTGAGCGG
GGAGATCGTTTTTTTTACCGGTATGACTGGGTATCAGGAAGTGCTGACCGACCCGTCGTATAAAAATCAAATCATCGTCT
TTACGTACCCACTGATCGGCAATTACGGCATCAATGATGAAGATTTTGAAAGCAAACGCCCGCATGTGGCAGCGGCCGTC
GTCTATGAGGCGAGCAACGAAGGGTTTCATTATGGAGTGAAATACAGCTTGGCTGAATATTTGCGGCACTGGAACATTCC
GCTGCTCACTCACGTTGATACGCGCGCCCTTGTCAAAGAAATTCGCATGGAAGGAACGATGATGGCAGAACTAAGCTCGT
CGCCCATCCCAGCGGTGATGGATGAAGAGACAACATTTCCTGTGTGCGCCGTGTCGACGAAAAAGATGGAGACGTACGGC
CAAGGCGGACCGCATATCGTGCTAATCGATTTCGGTTATAAAAAATCGATTTTACAGTCGCTCGTATCACGCGGCTGCCA
AGTAACCGTCGTGCCGCACGATACGGCGCCGGAAGCGATCGATGCGCTTAAACCGGATGGCCTTGTCCTCTCAAACGGCC
CCGGAGATCCGAAACAGCTAAGCGTTCGGCTTCCAGCCATTCGCCAGCTTATCGACCGGTATCCAACTTTAGCCATTTGC
CTCGGCCATCAGCTTGTTGCCTTGGCGTACGGGGCGGATACGGAAAAGCTTCGCTTCGGGCACCGCGGCGCCAACCAGCC
AGTGTGGGATGCTGTAAAACAAAAAGTGATGATCACGTCGCAAAACCATAGTTATGTCGTCAAAGAGAAAAGCCTTGAGG
GCAAGCCGTTTGCCATTCGTTTCATCAACATCAACGATGGCTCAGTGGAAGGCATGATCCATCGCGATAAACCAATTTTG
TCGGTGCAGTATCATCCGGAAGCTCATCCGGGGCCGCAAGATACCGGCTATATTTTCGATGAATTTTTGCAAACCGTCGC
AAAGGGAGAGAAAGTATATGCCTAA

Upstream 100 bases:

>100_bases
TCTTGTAATCAAATCAGGCAGTTGACGGCTTCATTTTTATTCTTGTTTTTGCATAAAAATTCTCTAACGGTTATAAAAAT
TAAACGATGAGGTGGCGCTA

Downstream 100 bases:

>100_bases
AGATTCCTCGCTTCAGTCGATTCTCCTGATTGGGTCGGGGCCGATCGTCATCGGCCAGGCCGCTGAGTTTGACTATTCTG
GGACGCAGGCATGCATCGCC

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MKAYLHLASGKTFSGKLATPLEKKVSGEIVFFTGMTGYQEVLTDPSYKNQIIVFTYPLIGNYGINDEDFESKRPHVAAAV
VYEASNEGFHYGVKYSLAEYLRHWNIPLLTHVDTRALVKEIRMEGTMMAELSSSPIPAVMDEETTFPVCAVSTKKMETYG
QGGPHIVLIDFGYKKSILQSLVSRGCQVTVVPHDTAPEAIDALKPDGLVLSNGPGDPKQLSVRLPAIRQLIDRYPTLAIC
LGHQLVALAYGADTEKLRFGHRGANQPVWDAVKQKVMITSQNHSYVVKEKSLEGKPFAIRFININDGSVEGMIHRDKPIL
SVQYHPEAHPGPQDTGYIFDEFLQTVAKGEKVYA

Sequences:

>Translated_354_residues
MKAYLHLASGKTFSGKLATPLEKKVSGEIVFFTGMTGYQEVLTDPSYKNQIIVFTYPLIGNYGINDEDFESKRPHVAAAV
VYEASNEGFHYGVKYSLAEYLRHWNIPLLTHVDTRALVKEIRMEGTMMAELSSSPIPAVMDEETTFPVCAVSTKKMETYG
QGGPHIVLIDFGYKKSILQSLVSRGCQVTVVPHDTAPEAIDALKPDGLVLSNGPGDPKQLSVRLPAIRQLIDRYPTLAIC
LGHQLVALAYGADTEKLRFGHRGANQPVWDAVKQKVMITSQNHSYVVKEKSLEGKPFAIRFININDGSVEGMIHRDKPIL
SVQYHPEAHPGPQDTGYIFDEFLQTVAKGEKVYA
>Mature_354_residues
MKAYLHLASGKTFSGKLATPLEKKVSGEIVFFTGMTGYQEVLTDPSYKNQIIVFTYPLIGNYGINDEDFESKRPHVAAAV
VYEASNEGFHYGVKYSLAEYLRHWNIPLLTHVDTRALVKEIRMEGTMMAELSSSPIPAVMDEETTFPVCAVSTKKMETYG
QGGPHIVLIDFGYKKSILQSLVSRGCQVTVVPHDTAPEAIDALKPDGLVLSNGPGDPKQLSVRLPAIRQLIDRYPTLAIC
LGHQLVALAYGADTEKLRFGHRGANQPVWDAVKQKVMITSQNHSYVVKEKSLEGKPFAIRFININDGSVEGMIHRDKPIL
SVQYHPEAHPGPQDTGYIFDEFLQTVAKGEKVYA

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=364, Percent_Identity=42.5824175824176, Blast_Score=254, Evalue=8e-68,
Organism=Homo sapiens, GI169790915, Length=345, Percent_Identity=36.231884057971, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI21361331, Length=345, Percent_Identity=36.231884057971, Blast_Score=217, Evalue=1e-56,
Organism=Escherichia coli, GI1786215, Length=380, Percent_Identity=38.1578947368421, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI1789760, Length=173, Percent_Identity=30.635838150289, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193204318, Length=369, Percent_Identity=41.4634146341463, Blast_Score=245, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6324878, Length=369, Percent_Identity=40.3794037940379, Blast_Score=255, Evalue=6e-69,
Organism=Saccharomyces cerevisiae, GI6322331, Length=394, Percent_Identity=38.5786802030457, Blast_Score=237, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6322638, Length=177, Percent_Identity=29.9435028248588, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45555749, Length=377, Percent_Identity=37.9310344827586, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24642586, Length=377, Percent_Identity=37.9310344827586, Blast_Score=238, Evalue=3e-63,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 39211; Mature: 39211

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAYLHLASGKTFSGKLATPLEKKVSGEIVFFTGMTGYQEVLTDPSYKNQIIVFTYPLIG
CCEEEEECCCCEECCCCCCCHHHHCCCCEEEEECCCCHHHHHCCCCCCCEEEEEEECCCC
NYGINDEDFESKRPHVAAAVVYEASNEGFHYGVKYSLAEYLRHWNIPLLTHVDTRALVKE
CCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEHHHHHHHHHHCCCCEEEECCHHHHHHH
IRMEGTMMAELSSSPIPAVMDEETTFPVCAVSTKKMETYGQGGPHIVLIDFGYKKSILQS
HHHCCEEEEECCCCCCCCEECCCCCCCEEEEEHHHHHHCCCCCCEEEEEECCCHHHHHHH
LVSRGCQVTVVPHDTAPEAIDALKPDGLVLSNGPGDPKQLSVRLPAIRQLIDRYPTLAIC
HHHCCCEEEEEECCCCCHHHHHCCCCCEEEECCCCCHHEEEEECHHHHHHHHHCCEEEEE
LGHQLVALAYGADTEKLRFGHRGANQPVWDAVKQKVMITSQNHSYVVKEKSLEGKPFAIR
HHCEEEEEEECCCHHHEEECCCCCCCHHHHHHHCEEEEEECCCEEEEEECCCCCCCEEEE
FININDGSVEGMIHRDKPILSVQYHPEAHPGPQDTGYIFDEFLQTVAKGEKVYA
EEEECCCCEEEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKAYLHLASGKTFSGKLATPLEKKVSGEIVFFTGMTGYQEVLTDPSYKNQIIVFTYPLIG
CCEEEEECCCCEECCCCCCCHHHHCCCCEEEEECCCCHHHHHCCCCCCCEEEEEEECCCC
NYGINDEDFESKRPHVAAAVVYEASNEGFHYGVKYSLAEYLRHWNIPLLTHVDTRALVKE
CCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEHHHHHHHHHHCCCCEEEECCHHHHHHH
IRMEGTMMAELSSSPIPAVMDEETTFPVCAVSTKKMETYGQGGPHIVLIDFGYKKSILQS
HHHCCEEEEECCCCCCCCEECCCCCCCEEEEEHHHHHHCCCCCCEEEEEECCCHHHHHHH
LVSRGCQVTVVPHDTAPEAIDALKPDGLVLSNGPGDPKQLSVRLPAIRQLIDRYPTLAIC
HHHCCCEEEEEECCCCCHHHHHCCCCCEEEECCCCCHHEEEEECHHHHHHHHHCCEEEEE
LGHQLVALAYGADTEKLRFGHRGANQPVWDAVKQKVMITSQNHSYVVKEKSLEGKPFAIR
HHCEEEEEEECCCHHHEEECCCCCCCHHHHHHHCEEEEEECCCEEEEEECCCCCCCEEEE
FININDGSVEGMIHRDKPILSVQYHPEAHPGPQDTGYIFDEFLQTVAKGEKVYA
EEEECCCCEEEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9370352 [H]