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The map label for this gene is argD [H]

Identifier: 138894345

GI number: 138894345

Start: 749874

End: 751034

Strand: Direct

Name: argD [H]

Synonym: GTNG_0673

Alternate gene names: 138894345

Gene position: 749874-751034 (Clockwise)

Preceding gene: 138894344

Following gene: 138894346

Centisome position: 21.12

GC content: 51.59

Gene sequence:

>1161_bases
ATGAGCGCACTGTTTCCAACCTACAACCGTTGGAAAATTTCTGTTCAATCGGCAGAAGGGACGGTTGTGACTGATGTCAA
TGGAAAACAATATCTCGATTTCGTGTCTGGCATTGCTGTTTGTAACCTCGGCCATCGTCATCCGCACGTCAAGAAAGCAA
TTGAAGAGCAGCTGAACCAATATTGGCACGTATCAAACTTGTTTACGATTCCGATTCAAGAAGAAGTCGCCTCCCAGCTT
GTTGCCCACAGCGCCGGCAATTACGTCTTTTTCTGCAACAGCGGAGCCGAGGCGAACGAAGCGGCGTTGAAGCTGGCACG
CAAACATACGGGAAGGCATAAAGTCATCACATTTCATCAGTCGTTTCACGGCCGAACGTTTGCGACGATGGCCGCGACCG
GGCAAGAGAAAGTGCATAGCGGATTTGGTCCATTATTGCCGGAATTTATACACTTGCCGTTTAACGATGCGAGCGCGCTC
GAGAAAGCGATGAACGATGAGATCGCGGCAGTGATGCTCGAGATCGTTCAAGGAGAAGGTGGTGTCCGCCCGATTGATCC
AGTGTTTTTGCAAACAGCTGCCGAGCTATGTCAAAAATACGGTGCGCTCTTGATCATTGACGAAGTACAAACCGGCATCG
GTCGGACCGGGAAGCCGTTTGCGTATCAACATTTTGGCATTGAGCCGGATATTATGACGGTCGCCAAAGGACTGGGCAGC
GGCATTCCGGTCGGTGCAATGATCGGCAAGGCGTTTTTAAAAGATTCATTCGGCCCTGGAGTGCACGGGTCGACGTTTGG
CGGCAACCCGATCGCGATGGCCGCCGCCAAGGCGACACTTGAAGTCGTGTTCGATTCGGCATTTTTACAAGAGGTTCAAG
AAAAAGGAAGCTACTTGCTTGGGCGGTTAAACGAGGCGCTCTCCCCGCTTGAAATTGTCAAGGACGTGCGCGGACTCGGA
CTGCTTGTTGGGGTGGAATGTCAAACGGAAATCGCTCCACTGTTGCCTTTGATTCATGAAAGCCGCTTGCTCGTTTTGCC
GGCCGGACCGAAGGTGATCCGACTGTTGCCACCGCTTGTCGTGACGAAAGACGAAATCGATCAAGCAGTGGATATTTTAA
CGGCAACATTGAAGAATGCCAACGCCTCGGCTGTCTTGTAA

Upstream 100 bases:

>100_bases
ATGCGTTGCCGAAAGTGATGATTGTCAGCGGCAAAACGCCGTTTTATGAGCAAGGAACATGGCACGGGACAACAATCCGT
AAAGAAGTGGGGGCATATTT

Downstream 100 bases:

>100_bases
TCAAATCAGGCAGTTGACGGCTTCATTTTTATTCTTGTTTTTGCATAAAAATTCTCTAACGGTTATAAAAATTAAACGAT
GAGGTGGCGCTAATGAAAGC

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MSALFPTYNRWKISVQSAEGTVVTDVNGKQYLDFVSGIAVCNLGHRHPHVKKAIEEQLNQYWHVSNLFTIPIQEEVASQL
VAHSAGNYVFFCNSGAEANEAALKLARKHTGRHKVITFHQSFHGRTFATMAATGQEKVHSGFGPLLPEFIHLPFNDASAL
EKAMNDEIAAVMLEIVQGEGGVRPIDPVFLQTAAELCQKYGALLIIDEVQTGIGRTGKPFAYQHFGIEPDIMTVAKGLGS
GIPVGAMIGKAFLKDSFGPGVHGSTFGGNPIAMAAAKATLEVVFDSAFLQEVQEKGSYLLGRLNEALSPLEIVKDVRGLG
LLVGVECQTEIAPLLPLIHESRLLVLPAGPKVIRLLPPLVVTKDEIDQAVDILTATLKNANASAVL

Sequences:

>Translated_386_residues
MSALFPTYNRWKISVQSAEGTVVTDVNGKQYLDFVSGIAVCNLGHRHPHVKKAIEEQLNQYWHVSNLFTIPIQEEVASQL
VAHSAGNYVFFCNSGAEANEAALKLARKHTGRHKVITFHQSFHGRTFATMAATGQEKVHSGFGPLLPEFIHLPFNDASAL
EKAMNDEIAAVMLEIVQGEGGVRPIDPVFLQTAAELCQKYGALLIIDEVQTGIGRTGKPFAYQHFGIEPDIMTVAKGLGS
GIPVGAMIGKAFLKDSFGPGVHGSTFGGNPIAMAAAKATLEVVFDSAFLQEVQEKGSYLLGRLNEALSPLEIVKDVRGLG
LLVGVECQTEIAPLLPLIHESRLLVLPAGPKVIRLLPPLVVTKDEIDQAVDILTATLKNANASAVL
>Mature_385_residues
SALFPTYNRWKISVQSAEGTVVTDVNGKQYLDFVSGIAVCNLGHRHPHVKKAIEEQLNQYWHVSNLFTIPIQEEVASQLV
AHSAGNYVFFCNSGAEANEAALKLARKHTGRHKVITFHQSFHGRTFATMAATGQEKVHSGFGPLLPEFIHLPFNDASALE
KAMNDEIAAVMLEIVQGEGGVRPIDPVFLQTAAELCQKYGALLIIDEVQTGIGRTGKPFAYQHFGIEPDIMTVAKGLGSG
IPVGAMIGKAFLKDSFGPGVHGSTFGGNPIAMAAAKATLEVVFDSAFLQEVQEKGSYLLGRLNEALSPLEIVKDVRGLGL
LVGVECQTEIAPLLPLIHESRLLVLPAGPKVIRLLPPLVVTKDEIDQAVDILTATLKNANASAVL

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=385, Percent_Identity=32.987012987013, Blast_Score=212, Evalue=5e-55,
Organism=Homo sapiens, GI13994255, Length=408, Percent_Identity=32.5980392156863, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=35.7859531772575, Blast_Score=178, Evalue=9e-45,
Organism=Homo sapiens, GI37574042, Length=410, Percent_Identity=30, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI226442705, Length=410, Percent_Identity=28.2926829268293, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI24119277, Length=418, Percent_Identity=30.3827751196172, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI226442709, Length=380, Percent_Identity=29.7368421052632, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI188536080, Length=431, Percent_Identity=24.1299303944316, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI38679950, Length=431, Percent_Identity=24.1299303944316, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI38679946, Length=431, Percent_Identity=24.1299303944316, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1789759, Length=377, Percent_Identity=41.3793103448276, Blast_Score=298, Evalue=5e-82,
Organism=Escherichia coli, GI1788044, Length=391, Percent_Identity=39.6419437340153, Blast_Score=291, Evalue=4e-80,
Organism=Escherichia coli, GI145693181, Length=377, Percent_Identity=37.6657824933687, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1787560, Length=396, Percent_Identity=36.3636363636364, Blast_Score=218, Evalue=7e-58,
Organism=Escherichia coli, GI1789016, Length=403, Percent_Identity=33.9950372208437, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1786991, Length=415, Percent_Identity=31.8072289156626, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1786349, Length=309, Percent_Identity=34.3042071197411, Blast_Score=143, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI25144271, Length=385, Percent_Identity=33.5064935064935, Blast_Score=221, Evalue=7e-58,
Organism=Caenorhabditis elegans, GI32564660, Length=432, Percent_Identity=31.9444444444444, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI25144274, Length=269, Percent_Identity=35.3159851301115, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=421, Percent_Identity=29.4536817102138, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17541228, Length=439, Percent_Identity=23.9179954441913, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71981843, Length=155, Percent_Identity=30.9677419354839, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324432, Length=370, Percent_Identity=37.2972972972973, Blast_Score=239, Evalue=5e-64,
Organism=Saccharomyces cerevisiae, GI6323470, Length=400, Percent_Identity=34, Blast_Score=199, Evalue=6e-52,
Organism=Saccharomyces cerevisiae, GI6324386, Length=435, Percent_Identity=24.8275862068966, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6321456, Length=363, Percent_Identity=26.7217630853994, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21357415, Length=383, Percent_Identity=32.6370757180157, Blast_Score=207, Evalue=7e-54,
Organism=Drosophila melanogaster, GI28574759, Length=420, Percent_Identity=31.9047619047619, Blast_Score=184, Evalue=7e-47,
Organism=Drosophila melanogaster, GI161085790, Length=413, Percent_Identity=30.9927360774818, Blast_Score=182, Evalue=5e-46,
Organism=Drosophila melanogaster, GI21356575, Length=420, Percent_Identity=29.2857142857143, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI281366494, Length=371, Percent_Identity=26.1455525606469, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24667139, Length=371, Percent_Identity=26.1455525606469, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24667143, Length=371, Percent_Identity=26.1455525606469, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 41516; Mature: 41385

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALFPTYNRWKISVQSAEGTVVTDVNGKQYLDFVSGIAVCNLGHRHPHVKKAIEEQLNQ
CCCCCCCCCEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
YWHVSNLFTIPIQEEVASQLVAHSAGNYVFFCNSGAEANEAALKLARKHTGRHKVITFHQ
HEECCCEEEECCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEC
SFHGRTFATMAATGQEKVHSGFGPLLPEFIHLPFNDASALEKAMNDEIAAVMLEIVQGEG
CCCCCEEEEEHHCCHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GVRPIDPVFLQTAAELCQKYGALLIIDEVQTGIGRTGKPFAYQHFGIEPDIMTVAKGLGS
CCCCCCHHHHHHHHHHHHHCCCEEEEECHHHCCCCCCCCCEEECCCCCCHHHHHHHHHCC
GIPVGAMIGKAFLKDSFGPGVHGSTFGGNPIAMAAAKATLEVVFDSAFLQEVQEKGSYLL
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRLNEALSPLEIVKDVRGLGLLVGVECQTEIAPLLPLIHESRLLVLPAGPKVIRLLPPLV
HHHHHHCCHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCE
VTKDEIDQAVDILTATLKNANASAVL
EEHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SALFPTYNRWKISVQSAEGTVVTDVNGKQYLDFVSGIAVCNLGHRHPHVKKAIEEQLNQ
CCCCCCCCEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
YWHVSNLFTIPIQEEVASQLVAHSAGNYVFFCNSGAEANEAALKLARKHTGRHKVITFHQ
HEECCCEEEECCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEC
SFHGRTFATMAATGQEKVHSGFGPLLPEFIHLPFNDASALEKAMNDEIAAVMLEIVQGEG
CCCCCEEEEEHHCCHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GVRPIDPVFLQTAAELCQKYGALLIIDEVQTGIGRTGKPFAYQHFGIEPDIMTVAKGLGS
CCCCCCHHHHHHHHHHHHHCCCEEEEECHHHCCCCCCCCCEEECCCCCCHHHHHHHHHCC
GIPVGAMIGKAFLKDSFGPGVHGSTFGGNPIAMAAAKATLEVVFDSAFLQEVQEKGSYLL
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRLNEALSPLEIVKDVRGLGLLVGVECQTEIAPLLPLIHESRLLVLPAGPKVIRLLPPLV
HHHHHHCCHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCE
VTKDEIDQAVDILTATLKNANASAVL
EEHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8473852; 9370352 [H]