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The map label for this gene is argB

Identifier: 138894344

GI number: 138894344

Start: 749101

End: 749877

Strand: Direct

Name: argB

Synonym: GTNG_0672

Alternate gene names: 138894344

Gene position: 749101-749877 (Clockwise)

Preceding gene: 138894343

Following gene: 138894345

Centisome position: 21.1

GC content: 55.34

Gene sequence:

>777_bases
ATGGAGAACACGGTCGTGATCAAATGCGGCGGCAGCGTGCTTGATGAGCTATCTCCCGCTTTTTTTGCCAGCGTGAAAAC
GATGCGCGAACAAGGGATGAATGTCGTCATCGTCCACGGTGGCGGGCCGGAGATTGGAAAGATGCTGAAACAGTTGAACG
TGCGAAGCGAATTTGTCAATGGTTTGCGCAAAACGACGAAAGAGGTGCTCGCCGTTGTGGAAATGGTGCTGTCCGGTAAA
GTGAACAAGCAGCTCGTCACGATGTTCAAGCAGCACGGTTTACCGGCAGTGGGCATTTCAGGGGTAGACGGAGGGCTGCT
TGAAGCGGAACCGATTGACGGGATTAAGCTTGGCTACGTCGGCCGCGTCACAGCTGTTCGCGTCGATTTGCTGCAAACGC
TACTTGCCGCAAACTACATACCGGTCATTTCACCGCTTGGCGTTGGTCGGAGCGGACAAACGTACAACATTAATGCGGAC
ACGGCAGCAGGGGCGATCGCGGCAGCCATCGGCGCCAATCAGCTCGCGTTTGTGACGAACGTGCCCGGCCTTTTGCAAGA
CGGGACGCTCATCGGGGAAGCAACAGCGGAAACGGTCGAGCAGCTGCTCAAAGACGGTGTCATCACCGGCGGGATGATCC
CGAAAGTGAAAGCGGCGCTCTCCGCCTTATCCGATGCGTTGCCGAAAGTGATGATTGTCAGCGGCAAAACGCCGTTTTAT
GAGCAAGGAACATGGCACGGGACAACAATCCGTAAAGAAGTGGGGGCATATTTATGA

Upstream 100 bases:

>100_bases
CCTTCATTTAGGTGATGGCTTTGGCATTGCATGGGGCTGCGACTTAACATATGATTACGTGAAAATTAACGCCAGTTACC
GGACATAAGGGGAGAGGAAA

Downstream 100 bases:

>100_bases
GCGCACTGTTTCCAACCTACAACCGTTGGAAAATTTCTGTTCAATCGGCAGAAGGGACGGTTGTGACTGATGTCAATGGA
AAACAATATCTCGATTTCGT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MENTVVIKCGGSVLDELSPAFFASVKTMREQGMNVVIVHGGGPEIGKMLKQLNVRSEFVNGLRKTTKEVLAVVEMVLSGK
VNKQLVTMFKQHGLPAVGISGVDGGLLEAEPIDGIKLGYVGRVTAVRVDLLQTLLAANYIPVISPLGVGRSGQTYNINAD
TAAGAIAAAIGANQLAFVTNVPGLLQDGTLIGEATAETVEQLLKDGVITGGMIPKVKAALSALSDALPKVMIVSGKTPFY
EQGTWHGTTIRKEVGAYL

Sequences:

>Translated_258_residues
MENTVVIKCGGSVLDELSPAFFASVKTMREQGMNVVIVHGGGPEIGKMLKQLNVRSEFVNGLRKTTKEVLAVVEMVLSGK
VNKQLVTMFKQHGLPAVGISGVDGGLLEAEPIDGIKLGYVGRVTAVRVDLLQTLLAANYIPVISPLGVGRSGQTYNINAD
TAAGAIAAAIGANQLAFVTNVPGLLQDGTLIGEATAETVEQLLKDGVITGGMIPKVKAALSALSDALPKVMIVSGKTPFY
EQGTWHGTTIRKEVGAYL
>Mature_258_residues
MENTVVIKCGGSVLDELSPAFFASVKTMREQGMNVVIVHGGGPEIGKMLKQLNVRSEFVNGLRKTTKEVLAVVEMVLSGK
VNKQLVTMFKQHGLPAVGISGVDGGLLEAEPIDGIKLGYVGRVTAVRVDLLQTLLAANYIPVISPLGVGRSGQTYNINAD
TAAGAIAAAIGANQLAFVTNVPGLLQDGTLIGEATAETVEQLLKDGVITGGMIPKVKAALSALSDALPKVMIVSGKTPFY
EQGTWHGTTIRKEVGAYL

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=226, Percent_Identity=39.8230088495575, Blast_Score=119, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320913, Length=259, Percent_Identity=26.2548262548263, Blast_Score=83, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_GEOTN (A4IL48)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001124797.1
- ProteinModelPortal:   A4IL48
- SMR:   A4IL48
- STRING:   A4IL48
- GeneID:   4965615
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_0672
- NMPDR:   fig|420246.5.peg.652
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- PhylomeDB:   A4IL48
- ProtClustDB:   PRK00942
- BioCyc:   GTHE420246:GTNG_0672-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 26982; Mature: 26982

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: BINDING 63-63 BINDING 156-156

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENTVVIKCGGSVLDELSPAFFASVKTMREQGMNVVIVHGGGPEIGKMLKQLNVRSEFVN
CCCEEEEEECCHHHHHCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
GLRKTTKEVLAVVEMVLSGKVNKQLVTMFKQHGLPAVGISGVDGGLLEAEPIDGIKLGYV
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCEEECCH
GRVTAVRVDLLQTLLAANYIPVISPLGVGRSGQTYNINADTAAGAIAAAIGANQLAFVTN
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCEEEEEC
VPGLLQDGTLIGEATAETVEQLLKDGVITGGMIPKVKAALSALSDALPKVMIVSGKTPFY
CCCHHCCCCEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCC
EQGTWHGTTIRKEVGAYL
CCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MENTVVIKCGGSVLDELSPAFFASVKTMREQGMNVVIVHGGGPEIGKMLKQLNVRSEFVN
CCCEEEEEECCHHHHHCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
GLRKTTKEVLAVVEMVLSGKVNKQLVTMFKQHGLPAVGISGVDGGLLEAEPIDGIKLGYV
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCEEECCH
GRVTAVRVDLLQTLLAANYIPVISPLGVGRSGQTYNINADTAAGAIAAAIGANQLAFVTN
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCEEEEEC
VPGLLQDGTLIGEATAETVEQLLKDGVITGGMIPKVKAALSALSDALPKVMIVSGKTPFY
CCCHHCCCCEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCC
EQGTWHGTTIRKEVGAYL
CCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA