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The map label for this gene is fnr [H]

Identifier: 138894314

GI number: 138894314

Start: 715571

End: 716263

Strand: Reverse

Name: fnr [H]

Synonym: GTNG_0642

Alternate gene names: 138894314

Gene position: 716263-715571 (Counterclockwise)

Preceding gene: 138894323

Following gene: 138894313

Centisome position: 20.17

GC content: 46.32

Gene sequence:

>693_bases
ATGGCGAACCATTGGATGAAAGATCGTTTAAAAACGGTTCCGTTGTTTCGCGAACTGTCCGATTACGAACTCGAATCGCT
TGTCTCCATTTCCCATGTGCGCGTCTACAAGCCGCGGACATTTGTCTTTATGCAGGGCGATCCGTTAGAACGTGTCTATT
TCATTCATTCTGGAACTGTAAAAATTTACAAAACTGATTTAAGCGGAAAAGAACAAATCGTCTCGATTTTGCAGACAGGG
GAAATGTTTCCGCACGCCGGCTTCTTCTTAAAAGGCACGTACCCAGCCCATGCTGAAGTGGTGGAAGAAGCGACATTGAT
CGCCATTCCGATCCATGATTTTGAACAAGTGCTGATGGCCAGTCCTGAGTTATGCATGAAACTGTTTCGCGTTATGGGCG
AGAAAATCGTTGACTTGCAAAACCGGCTCGAAGCACAAGTGCTTCATAATACGTACGAACAAATCGTGCTGCTTTTGTTG
CGATTGACGCGGACAAATGCTGTCAAACAAGGGAAATGGTATCGCCTCACTACCCATGTGACGAACCGTGAACTGGCCAA
CATGATCGGTACCGCCCGCGAAACAGTCAGCCGAACGTTGAGCCAACTGAAGCGGAAAGGGTTGATCAATGTCGATGAAC
ACGGCTTTTATTTGATCGACCAGGAAGCGCTTGAAAAAGAAATCTTTTTCTAA

Upstream 100 bases:

>100_bases
GACAGAAAAGGTGAAACGGCGCGGATTTCCAAAAGCCGCTGCCACCTGTTCCAACTAACAGCTGTCACATTTTTTTCATA
TTTTTAAAGGAGAGAACGCC

Downstream 100 bases:

>100_bases
TTCCCCGTATGTCTAAAAGAGTGGCGATTTCATCAAAACCGCTGCACAAAAAGGCGCTTCTCTAATAGATACACCTTGAT
GTTTAGCGCTCTCCAAAACC

Product: cAMP-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MANHWMKDRLKTVPLFRELSDYELESLVSISHVRVYKPRTFVFMQGDPLERVYFIHSGTVKIYKTDLSGKEQIVSILQTG
EMFPHAGFFLKGTYPAHAEVVEEATLIAIPIHDFEQVLMASPELCMKLFRVMGEKIVDLQNRLEAQVLHNTYEQIVLLLL
RLTRTNAVKQGKWYRLTTHVTNRELANMIGTARETVSRTLSQLKRKGLINVDEHGFYLIDQEALEKEIFF

Sequences:

>Translated_230_residues
MANHWMKDRLKTVPLFRELSDYELESLVSISHVRVYKPRTFVFMQGDPLERVYFIHSGTVKIYKTDLSGKEQIVSILQTG
EMFPHAGFFLKGTYPAHAEVVEEATLIAIPIHDFEQVLMASPELCMKLFRVMGEKIVDLQNRLEAQVLHNTYEQIVLLLL
RLTRTNAVKQGKWYRLTTHVTNRELANMIGTARETVSRTLSQLKRKGLINVDEHGFYLIDQEALEKEIFF
>Mature_229_residues
ANHWMKDRLKTVPLFRELSDYELESLVSISHVRVYKPRTFVFMQGDPLERVYFIHSGTVKIYKTDLSGKEQIVSILQTGE
MFPHAGFFLKGTYPAHAEVVEEATLIAIPIHDFEQVLMASPELCMKLFRVMGEKIVDLQNRLEAQVLHNTYEQIVLLLLR
LTRTNAVKQGKWYRLTTHVTNRELANMIGTARETVSRTLSQLKRKGLINVDEHGFYLIDQEALEKEIFF

Specific function: It is involved in the activation of genes necessary for anaerobic respiration [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=214, Percent_Identity=26.6355140186916, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1789756, Length=207, Percent_Identity=25.6038647342995, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 26698; Mature: 26567

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS50042 CNMP_BINDING_3 ; PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANHWMKDRLKTVPLFRELSDYELESLVSISHVRVYKPRTFVFMQGDPLERVYFIHSGTV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCEEEEEECCCCCCEEEEEECCEE
KIYKTDLSGKEQIVSILQTGEMFPHAGFFLKGTYPAHAEVVEEATLIAIPIHDFEQVLMA
EEEEECCCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHCCCEEEEEEHHHHHHHHHC
SPELCMKLFRVMGEKIVDLQNRLEAQVLHNTYEQIVLLLLRLTRTNAVKQGKWYRLTTHV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEH
TNRELANMIGTARETVSRTLSQLKRKGLINVDEHGFYLIDQEALEKEIFF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEECHHHHHHHCCC
>Mature Secondary Structure 
ANHWMKDRLKTVPLFRELSDYELESLVSISHVRVYKPRTFVFMQGDPLERVYFIHSGTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCEEEEEECCCCCCEEEEEECCEE
KIYKTDLSGKEQIVSILQTGEMFPHAGFFLKGTYPAHAEVVEEATLIAIPIHDFEQVLMA
EEEEECCCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHCCCEEEEEEHHHHHHHHHC
SPELCMKLFRVMGEKIVDLQNRLEAQVLHNTYEQIVLLLLRLTRTNAVKQGKWYRLTTHV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEH
TNRELANMIGTARETVSRTLSQLKRKGLINVDEHGFYLIDQEALEKEIFF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEECHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8846791; 9384377 [H]