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The map label for this gene is dppA [H]

Identifier: 138894152

GI number: 138894152

Start: 532037

End: 533641

Strand: Direct

Name: dppA [H]

Synonym: GTNG_0478

Alternate gene names: 138894152

Gene position: 532037-533641 (Clockwise)

Preceding gene: 138894151

Following gene: 138894153

Centisome position: 14.99

GC content: 47.6

Gene sequence:

>1605_bases
ATGAGAAGAAACAAATGGTTTACCTGGCTGGCCATGCTGCTTGCCGTTGTGCTTGTCTTTGCCGGCTGCAGCAAGCCGAA
GGAAAGCACAGGGGGCAGCAGCGAAAAACCATCGGCCCAAGACACTCTTGTCTATGGCCGCGGTGGCGATTCGGTATCGC
TTGACCCGGCGACAGTGACGGATGGTGAGTCGCTCAAAGTCACGAAAAACATTTTTGACACACTGCTTGACTACAACGAT
AACGACACATCCGTTAAGCCAGCATTGGCGACGAAGTGGACGGTTTCTGAGGATGGACTGACGTACACTTTCGAGTTGCG
TCAAGGTGTAAAGTTTCATGATGGCACGGATTTTTACGCTGAAGCAGTTGTATTCAACTTTGAGCGTTGGGCAAACGGCA
ATGAAGCCTTTTTCCCATACTATGGCTCGATGTTTGGCGGCTATAAAACCGTTGAAGGCCATGTCATTAAAGAGGTGAAA
GCGATTGATGACTATACCGTACAGTTTGTGCTGAAGCGTCCGCAAGCGCCGTTCTTGAAAAATATCGCCATGCCGCCGTT
TGCCATTGCCAGCCCAGAAGCTGTGAAAAAATACGGTGACAAATTTGGCGAACATCCGGTTGGCACCGGACCGTTTATCT
TTAAAGAGTGGAAACGAAACGAACGGATCATGCTTGAGAAAAATAAAGAATATTGGGAAAAAGGTTATCCGAAGTTGAAT
CAGCTTATTTTCGTTTCCATTCCGGACAACTCAGCGCGCCTCAATGCCCTTTTAAAAGGGGAAATCGATATCATGGAAGA
CTTGAACCCGACGGACTTAAAACAAGTGGAAGGAAACAAAGAGTTTCAAATTTTTAAGCGTCCGTCGATGAACGTCGCCT
ATGTTGGACTGACAGCGACGAGAGGCCCTCTGAAAAACAAACTGGTGCGCCAAGCGTTGAACCATGCAGTCGATAAGAAA
GCAATCATCGATGCGTTTTACGCCGGACAGGCGGAAGTGGCAAAAAATCCGATGCCACCGAGCATTCCAGGGTATAACGA
TGCCATTCAAGACTACCCGTTTGATCTAGAAAAAGCCAAACAATTGCTCGCGGAGGCCGGATACCCGAACGGCTTTGAAA
TCGAACTTTGGGCGATGCCGGTGCCGCGTCCGTATATGCCGGATGGGCAAAAAATCGCTGAAGCCATTCAAGCAAACTTT
GCCAAAATCGGTGTCAAAGCGAAAATTGTGTCATATGAATGGGCGACTTACTTAGAGAAGCTCGCTAAAGGGGAAGCGGA
TACCTTCATGCTCGGTTGGACCGGCGACAACGGTGATGCGGATAACTTCCTATACGCGCTCCTTGACAAAGACAGCATTG
GCAGCAACAACTACACGTATTTTGCGAACGATGAGCTTCATAACATTTTAGTTGAGGCGCAAACAGTCAGCGATGAAAAT
AAACGCAATGAGCTGTATAAACAGGCACAAGAAATTATTAAAGAAGAGGCACCGTGGATTCCGCTCGTTCACTCGACTCC
GCTGTTAGCCGGCAAGACAAATATTCAAGGGTTTCATCCGCATCCGACTGGCTCAGACAAATTTACAAAAGTGGAATTTC
AATAA

Upstream 100 bases:

>100_bases
CATTAAAAGAAGTAGCGACTGGACATTACGTCGCCTGCCATTTATATGAATAAACAGCAGGCGGTGTGATGATAGACAAA
ACAAGTAAGGGGGAGAAACG

Downstream 100 bases:

>100_bases
TCAGTTGGGAGAGGGGAAGGAGCGCATCTTCCCCTCTTTGTTTACCGCACGTTAAGGGAGGGATACTTGGGTGCTGTCGT
ATATAGTGAGAAGGGTGCTG

Product: peptide ABC transporter

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 534; Mature: 534

Protein sequence:

>534_residues
MRRNKWFTWLAMLLAVVLVFAGCSKPKESTGGSSEKPSAQDTLVYGRGGDSVSLDPATVTDGESLKVTKNIFDTLLDYND
NDTSVKPALATKWTVSEDGLTYTFELRQGVKFHDGTDFYAEAVVFNFERWANGNEAFFPYYGSMFGGYKTVEGHVIKEVK
AIDDYTVQFVLKRPQAPFLKNIAMPPFAIASPEAVKKYGDKFGEHPVGTGPFIFKEWKRNERIMLEKNKEYWEKGYPKLN
QLIFVSIPDNSARLNALLKGEIDIMEDLNPTDLKQVEGNKEFQIFKRPSMNVAYVGLTATRGPLKNKLVRQALNHAVDKK
AIIDAFYAGQAEVAKNPMPPSIPGYNDAIQDYPFDLEKAKQLLAEAGYPNGFEIELWAMPVPRPYMPDGQKIAEAIQANF
AKIGVKAKIVSYEWATYLEKLAKGEADTFMLGWTGDNGDADNFLYALLDKDSIGSNNYTYFANDELHNILVEAQTVSDEN
KRNELYKQAQEIIKEEAPWIPLVHSTPLLAGKTNIQGFHPHPTGSDKFTKVEFQ

Sequences:

>Translated_534_residues
MRRNKWFTWLAMLLAVVLVFAGCSKPKESTGGSSEKPSAQDTLVYGRGGDSVSLDPATVTDGESLKVTKNIFDTLLDYND
NDTSVKPALATKWTVSEDGLTYTFELRQGVKFHDGTDFYAEAVVFNFERWANGNEAFFPYYGSMFGGYKTVEGHVIKEVK
AIDDYTVQFVLKRPQAPFLKNIAMPPFAIASPEAVKKYGDKFGEHPVGTGPFIFKEWKRNERIMLEKNKEYWEKGYPKLN
QLIFVSIPDNSARLNALLKGEIDIMEDLNPTDLKQVEGNKEFQIFKRPSMNVAYVGLTATRGPLKNKLVRQALNHAVDKK
AIIDAFYAGQAEVAKNPMPPSIPGYNDAIQDYPFDLEKAKQLLAEAGYPNGFEIELWAMPVPRPYMPDGQKIAEAIQANF
AKIGVKAKIVSYEWATYLEKLAKGEADTFMLGWTGDNGDADNFLYALLDKDSIGSNNYTYFANDELHNILVEAQTVSDEN
KRNELYKQAQEIIKEEAPWIPLVHSTPLLAGKTNIQGFHPHPTGSDKFTKVEFQ
>Mature_534_residues
MRRNKWFTWLAMLLAVVLVFAGCSKPKESTGGSSEKPSAQDTLVYGRGGDSVSLDPATVTDGESLKVTKNIFDTLLDYND
NDTSVKPALATKWTVSEDGLTYTFELRQGVKFHDGTDFYAEAVVFNFERWANGNEAFFPYYGSMFGGYKTVEGHVIKEVK
AIDDYTVQFVLKRPQAPFLKNIAMPPFAIASPEAVKKYGDKFGEHPVGTGPFIFKEWKRNERIMLEKNKEYWEKGYPKLN
QLIFVSIPDNSARLNALLKGEIDIMEDLNPTDLKQVEGNKEFQIFKRPSMNVAYVGLTATRGPLKNKLVRQALNHAVDKK
AIIDAFYAGQAEVAKNPMPPSIPGYNDAIQDYPFDLEKAKQLLAEAGYPNGFEIELWAMPVPRPYMPDGQKIAEAIQANF
AKIGVKAKIVSYEWATYLEKLAKGEADTFMLGWTGDNGDADNFLYALLDKDSIGSNNYTYFANDELHNILVEAQTVSDEN
KRNELYKQAQEIIKEEAPWIPLVHSTPLLAGKTNIQGFHPHPTGSDKFTKVEFQ

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=510, Percent_Identity=41.5686274509804, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI1787052, Length=504, Percent_Identity=32.7380952380952, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI1787551, Length=547, Percent_Identity=28.7020109689214, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1787762, Length=544, Percent_Identity=27.3897058823529, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1787495, Length=484, Percent_Identity=28.5123966942149, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1789397, Length=514, Percent_Identity=26.8482490272374, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1789887, Length=460, Percent_Identity=28.4782608695652, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI87081878, Length=524, Percent_Identity=25.5725190839695, Blast_Score=155, Evalue=5e-39,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59965; Mature: 59965

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRNKWFTWLAMLLAVVLVFAGCSKPKESTGGSSEKPSAQDTLVYGRGGDSVSLDPATVT
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEECCCCEEC
DGESLKVTKNIFDTLLDYNDNDTSVKPALATKWTVSEDGLTYTFELRQGVKFHDGTDFYA
CCCCEEEHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCHHH
EAVVFNFERWANGNEAFFPYYGSMFGGYKTVEGHVIKEVKAIDDYTVQFVLKRPQAPFLK
HHHEEEHHHHCCCCCEECCCHHHHCCCCEEECCHHHHHHHHHCHHEEEEEEECCCCCHHH
NIAMPPFAIASPEAVKKYGDKFGEHPVGTGPFIFKEWKRNERIMLEKNKEYWEKGYPKLN
HCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCEEEECCHHHHHCCCCCCC
QLIFVSIPDNSARLNALLKGEIDIMEDLNPTDLKQVEGNKEFQIFKRPSMNVAYVGLTAT
CEEEEEECCCCHHEEEEEECCCHHHHCCCCCHHHHCCCCCCEEEEECCCCCEEEEEEECC
RGPLKNKLVRQALNHAVDKKAIIDAFYAGQAEVAKNPMPPSIPGYNDAIQDYPFDLEKAK
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCHHHCCCCCHHHHH
QLLAEAGYPNGFEIELWAMPVPRPYMPDGQKIAEAIQANFAKIGVKAKIVSYEWATYLEK
HHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCEEEEEEEHHHHHHHHH
LAKGEADTFMLGWTGDNGDADNFLYALLDKDSIGSNNYTYFANDELHNILVEAQTVSDEN
HHCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCEEEEECCCCEEEEEEEECCCCCH
KRNELYKQAQEIIKEEAPWIPLVHSTPLLAGKTNIQGFHPHPTGSDKFTKVEFQ
HHHHHHHHHHHHHHHCCCCEEEEECCCCEECCCCCCCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MRRNKWFTWLAMLLAVVLVFAGCSKPKESTGGSSEKPSAQDTLVYGRGGDSVSLDPATVT
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEECCCCEEC
DGESLKVTKNIFDTLLDYNDNDTSVKPALATKWTVSEDGLTYTFELRQGVKFHDGTDFYA
CCCCEEEHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCHHH
EAVVFNFERWANGNEAFFPYYGSMFGGYKTVEGHVIKEVKAIDDYTVQFVLKRPQAPFLK
HHHEEEHHHHCCCCCEECCCHHHHCCCCEEECCHHHHHHHHHCHHEEEEEEECCCCCHHH
NIAMPPFAIASPEAVKKYGDKFGEHPVGTGPFIFKEWKRNERIMLEKNKEYWEKGYPKLN
HCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCEEEECCHHHHHCCCCCCC
QLIFVSIPDNSARLNALLKGEIDIMEDLNPTDLKQVEGNKEFQIFKRPSMNVAYVGLTAT
CEEEEEECCCCHHEEEEEECCCHHHHCCCCCHHHHCCCCCCEEEEECCCCCEEEEEEECC
RGPLKNKLVRQALNHAVDKKAIIDAFYAGQAEVAKNPMPPSIPGYNDAIQDYPFDLEKAK
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCHHHCCCCCHHHHH
QLLAEAGYPNGFEIELWAMPVPRPYMPDGQKIAEAIQANFAKIGVKAKIVSYEWATYLEK
HHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCEEEEEEEHHHHHHHHH
LAKGEADTFMLGWTGDNGDADNFLYALLDKDSIGSNNYTYFANDELHNILVEAQTVSDEN
HHCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCEEEEECCCCEEEEEEEECCCCCH
KRNELYKQAQEIIKEEAPWIPLVHSTPLLAGKTNIQGFHPHPTGSDKFTKVEFQ
HHHHHHHHHHHHHHHCCCCEEEEECCCCEECCCCCCCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]