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The map label for this gene is yfkJ [H]

Identifier: 138894065

GI number: 138894065

Start: 441623

End: 442105

Strand: Direct

Name: yfkJ [H]

Synonym: GTNG_0391

Alternate gene names: 138894065

Gene position: 441623-442105 (Clockwise)

Preceding gene: 138894056

Following gene: 138894066

Centisome position: 12.44

GC content: 50.72

Gene sequence:

>483_bases
ATGGTCAAAGTGTTGTTTGTTTGCCTTGGAAACATTTGCCGTTCACCGATGGCCGAAGCGATATTCCGCCATTTAGTGAA
AGAGCGGGGGCTCGATAGGGTTATTGCCGTTGATTCGGCGGGGACGGGCAGTTGGCATGTCGGCGAACCGCCACATGAAG
GGACAAGACGCATCTTAAACGAAAACGACATTGATTATTCCGGCATCCGTGCCCGGCAAGTCGAACGCCGCGATTTGGAG
GAATTTGATTATATTATCGCCATGGATGCCGCCAACTTGAACGATTTACGCCGACTAGCTGGATCCAATTCATCGGCCGT
AATCGCCCGCTTGCTCGATTTTGTGCCGGATCGGGAAAAAGACGATGTGCCGGATCCATATTATACTGGGAATTTCGTGG
AAGTATATCACCTTGTCCGTTCTGGATGCGAGCATTTGCTTGAGGCGATTATCCGTGATCATCGGCTTGTTGCGGGCGAA
TAA

Upstream 100 bases:

>100_bases
TATGCCGGAAAGCAGCATAAAAAGTCTAGACGAAAGGAAAAGAAGAAAAACTAATGATCGGAGACGTGCCGTAGAAATAG
CGAAAGGGGTTGTTGTTCGG

Downstream 100 bases:

>100_bases
AGAGGAGCAAAAAGGGATGCACTCGCTTTGAAAAAACGGGAAAGGAGGGCAGCCCGTGTTAGTGAATATGATGTTCGTCC
GCGAGTTGGCGCGGCGCTTT

Product: low molecular weight phosphotyrosine protein

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MVKVLFVCLGNICRSPMAEAIFRHLVKERGLDRVIAVDSAGTGSWHVGEPPHEGTRRILNENDIDYSGIRARQVERRDLE
EFDYIIAMDAANLNDLRRLAGSNSSAVIARLLDFVPDREKDDVPDPYYTGNFVEVYHLVRSGCEHLLEAIIRDHRLVAGE

Sequences:

>Translated_160_residues
MVKVLFVCLGNICRSPMAEAIFRHLVKERGLDRVIAVDSAGTGSWHVGEPPHEGTRRILNENDIDYSGIRARQVERRDLE
EFDYIIAMDAANLNDLRRLAGSNSSAVIARLLDFVPDREKDDVPDPYYTGNFVEVYHLVRSGCEHLLEAIIRDHRLVAGE
>Mature_160_residues
MVKVLFVCLGNICRSPMAEAIFRHLVKERGLDRVIAVDSAGTGSWHVGEPPHEGTRRILNENDIDYSGIRARQVERRDLE
EFDYIIAMDAANLNDLRRLAGSNSSAVIARLLDFVPDREKDDVPDPYYTGNFVEVYHLVRSGCEHLLEAIIRDHRLVAGE

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=149, Percent_Identity=39.5973154362416, Blast_Score=103, Evalue=8e-23,
Organism=Homo sapiens, GI6005988, Length=149, Percent_Identity=38.255033557047, Blast_Score=100, Evalue=4e-22,
Organism=Homo sapiens, GI96304457, Length=78, Percent_Identity=46.1538461538462, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6325330, Length=130, Percent_Identity=36.9230769230769, Blast_Score=100, Evalue=2e-22,
Organism=Drosophila melanogaster, GI78706770, Length=148, Percent_Identity=40.5405405405405, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI78706772, Length=148, Percent_Identity=40.5405405405405, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI78711846, Length=160, Percent_Identity=37.5, Blast_Score=106, Evalue=7e-24,
Organism=Drosophila melanogaster, GI78706764, Length=130, Percent_Identity=40, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI78706766, Length=126, Percent_Identity=40.4761904761905, Blast_Score=96, Evalue=9e-21,
Organism=Drosophila melanogaster, GI78706768, Length=126, Percent_Identity=40.4761904761905, Blast_Score=96, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24648069, Length=156, Percent_Identity=32.6923076923077, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 18102; Mature: 18102

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVLFVCLGNICRSPMAEAIFRHLVKERGLDRVIAVDSAGTGSWHVGEPPHEGTRRILN
CHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHC
ENDIDYSGIRARQVERRDLEEFDYIIAMDAANLNDLRRLAGSNSSAVIARLLDFVPDREK
CCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCC
DDVPDPYYTGNFVEVYHLVRSGCEHLLEAIIRDHRLVAGE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVKVLFVCLGNICRSPMAEAIFRHLVKERGLDRVIAVDSAGTGSWHVGEPPHEGTRRILN
CHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHC
ENDIDYSGIRARQVERRDLEEFDYIIAMDAANLNDLRRLAGSNSSAVIARLLDFVPDREK
CCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCC
DDVPDPYYTGNFVEVYHLVRSGCEHLLEAIIRDHRLVAGE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]