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The map label for this gene is moaC [H]

Identifier: 138893892

GI number: 138893892

Start: 236471

End: 236959

Strand: Direct

Name: moaC [H]

Synonym: GTNG_0216

Alternate gene names: 138893892

Gene position: 236471-236959 (Clockwise)

Preceding gene: 138893890

Following gene: 138893893

Centisome position: 6.66

GC content: 49.69

Gene sequence:

>489_bases
TTGTCGTCGTTTACTCATTTCAATGAGCAAGGCCGCGCGAAAATGGTCGATATTACGAACAAGGAAGATACGGTGCGGGT
CGCAGTGGCAAAAACGAGCGTCACCGTCAGCGAAGAGATTTATGAAAAAATGACAAACAACGCCATCGAGAAAGGTGACG
TGTTGGCAGTGGCCCAAGTGGCCGGGGTGATGGCAGCGAAAAAAACAGCCGATCTCATTCCGATGTGCCATCCGCTCATG
TTAAAAGGTGTCGATATCGCATTTTCATGGGAAAACGAAGCGGATGCATATAAACTCGTCATCACCGCAACAGTGAAAAC
GAAAGGGAGCACAGGGGTGGAAATGGAAGCGCTGACGGCCGCCTCGGTATGTGCGTTGACGGTGTATGATATGTGTAAAG
CACTTGATAAAGGGATGATCATCGGTCCGACGTATTTGGTCGAGAAAACGGGCGGAAAGTCCGGCCATTATCGACGGAAA
ACCGATTAG

Upstream 100 bases:

>100_bases
ATGTCGTTTCACCTCTCGGAATAGTTTAACGTATGTCGCCAAAACGGTCAAAGACAGATAAACAAAAATCGTGTATAGTG
TATAATTGGAGGAGATTGTT

Downstream 100 bases:

>100_bases
CTGGGGGATGAAATGATGAGTAACGAACAACCGAAAATTCCGCAAGCAACCGCGAAGCGGCTGCCGCTGTACTACCGGTT
TTTGAAGAATTTGCATGCGT

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MSSFTHFNEQGRAKMVDITNKEDTVRVAVAKTSVTVSEEIYEKMTNNAIEKGDVLAVAQVAGVMAAKKTADLIPMCHPLM
LKGVDIAFSWENEADAYKLVITATVKTKGSTGVEMEALTAASVCALTVYDMCKALDKGMIIGPTYLVEKTGGKSGHYRRK
TD

Sequences:

>Translated_162_residues
MSSFTHFNEQGRAKMVDITNKEDTVRVAVAKTSVTVSEEIYEKMTNNAIEKGDVLAVAQVAGVMAAKKTADLIPMCHPLM
LKGVDIAFSWENEADAYKLVITATVKTKGSTGVEMEALTAASVCALTVYDMCKALDKGMIIGPTYLVEKTGGKSGHYRRK
TD
>Mature_161_residues
SSFTHFNEQGRAKMVDITNKEDTVRVAVAKTSVTVSEEIYEKMTNNAIEKGDVLAVAQVAGVMAAKKTADLIPMCHPLML
KGVDIAFSWENEADAYKLVITATVKTKGSTGVEMEALTAASVCALTVYDMCKALDKGMIIGPTYLVEKTGGKSGHYRRKT
D

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=162, Percent_Identity=50, Blast_Score=160, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI32566331, Length=153, Percent_Identity=44.4444444444444, Blast_Score=144, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28574490, Length=159, Percent_Identity=46.5408805031447, Blast_Score=143, Evalue=6e-35,
Organism=Drosophila melanogaster, GI28574492, Length=146, Percent_Identity=46.5753424657534, Blast_Score=130, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17514; Mature: 17383

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSFTHFNEQGRAKMVDITNKEDTVRVAVAKTSVTVSEEIYEKMTNNAIEKGDVLAVAQV
CCCCCCCCCCCCEEEEEECCCCCEEEEEEEECEEEHHHHHHHHHHCCCCCCCCEEHHHHH
AGVMAAKKTADLIPMCHPLMLKGVDIAFSWENEADAYKLVITATVKTKGSTGVEMEALTA
HHHHHHHHHHHHCCCCCHHHHCCCEEEEEECCCCCEEEEEEEEEEEECCCCCCEEHHHHH
ASVCALTVYDMCKALDKGMIIGPTYLVEKTGGKSGHYRRKTD
HHHHHHHHHHHHHHHCCCEEECCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SSFTHFNEQGRAKMVDITNKEDTVRVAVAKTSVTVSEEIYEKMTNNAIEKGDVLAVAQV
CCCCCCCCCCCEEEEEECCCCCEEEEEEEECEEEHHHHHHHHHHCCCCCCCCEEHHHHH
AGVMAAKKTADLIPMCHPLMLKGVDIAFSWENEADAYKLVITATVKTKGSTGVEMEALTA
HHHHHHHHHHHHCCCCCHHHHCCCEEEEEECCCCCEEEEEEEEEEEECCCCCCEEHHHHH
ASVCALTVYDMCKALDKGMIIGPTYLVEKTGGKSGHYRRKTD
HHHHHHHHHHHHHHHCCCEEECCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA