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The map label for this gene is uup [H]

Identifier: 138893891

GI number: 138893891

Start: 234441

End: 236372

Strand: Reverse

Name: uup [H]

Synonym: GTNG_0215

Alternate gene names: 138893891

Gene position: 236372-234441 (Counterclockwise)

Preceding gene: 138893896

Following gene: 138893878

Centisome position: 6.66

GC content: 49.02

Gene sequence:

>1932_bases
ATGATCATTTTGCAAGTGCACCAGCTCACGAAATATTTTGGCGCTGACCTTATTTTATCGAATATAAAACTAGAAGTACA
ATCCCGTGACCGAATCGCCCTCGTCGGCCGCAACGGCGCAGGAAAATCGACATTGTTAAAAATCATCGCCGGAGAACTTT
CTTATGACAGCGGCGAAATCATCAAGCCTAGTCATATTAAGATTGGCTATTTGGCACAAAATAGCGGGCTTGACTCGTCG
CGCTCTATTTGGGACGAGATGCTCGAAGTGTTCGCGCCACTTCTAGCCATCGAAAAGCAGCTAGCAGCACTCGGCTCCCA
ACTTGGTGACCCGGATGTACTCGCTGACCCTGCCCGCTATGAAAAAATACTCAAAGCGTATGACGAACTACAAGAACAAT
ATAAAGAACAGGGCGGCTATCAATATGAAGCCGACATCCGTTCGGTCTTACACGGTCTGCAGTTTTCTTCCTATGATTAT
AAAACAACGCTTATCTCCTCATTAAGCGGTGGGCAGCGGACACGTCTCGCTCTCGGGAAGCTTCTATTGTCTAAGCCAGA
TTTGTTGATTTTGGACGAGCCGACCAACCATTTGGATCTTGAAACACTCTCCTGGTTGGAACAATACTTGCAGGCGTACC
CCGGTGCCGTCCTGCTCGTTTCCCATGATCGCTATTTTTTGGATAAAGTCGTCACGGAAGTATACGAGCTATCCAACACG
AAGCTCAAGCGGTATACAGGCAACTACAGCCGCTATTTGGAGCAGCGGGCCGAACAGTATGAACAAGAATTAAAACGATA
TGAGAAACAGCAAGAAGAAATCGCCCGGCTGCAAGACTTTATCCAGCGCAACATCGCCCGTGCCTCGACGACCAAACGCG
CGCAAAGCCGTCGAAAACAACTAGAAAAAATGGAACGGCTTGAACGCCCCACTGGCGATGGAAAATCGGCATCCTTTTCC
TTTACAATTGAACGGCCGAGCGGCCATGAAGTACTCACCGCTGAGGAACTAGCCGTTGGTTACGGCGAAGGAACACCTGT
CATCCGCCAAATCAGCTTTCGCATCACGCGAGGAGAAAGCGTCGCCTTAGTCGGACCGAACGGCATCGGTAAATCAACAT
TGCTAAAGGCGGTCGCGCAGCGGCTTCCTGTCCAAGCGGGAAAGCTTCGCTACGGCTCAAACGTCCAAATCGGCTATTAT
GATCAAAATCAGGCCGAATTGTCATCGAATAAACGAGTGCTGGATGAGCTATGGGACGACTACCCAGATAAAACCGAGAA
GGAAATCCGTACCGTGCTCGGTAACTTTTTGTTTTCCGGAGATGACGTTTTAAAACCAGTCTCGGCGTTAAGCGGTGGGG
AAAAAGCGCGTCTAGCGCTCGCCAAACTGATGCTCCAAAAAGCGAACGTTCTTATTTTGGACGAGCCAACCAACCATTTG
GATCTCGATAGCAAACAGGTGCTCGAGCAAGCGCTCATCGACTATCCAGGCACCATTTTGTTCGTCTCCCACGACCGCTA
CTTCATTAACCGGATTGCGACAAAGCTGTTTGAGCTATCGAGCGATGGCCTCACCGAATATTTAGGTGACTACGATTACT
ACATCGCCAAAAAAGCGGAGATGTGCGAATTGGAGCGCCTTGACGCCCGTCCTGACAAAACGCAGGATAGCAACGAATCG
AGCAAATCCGCTTATAAGCAAGAAAAGGAAGAGAAAAAACGGCAGCGCCAGCGCCAGCGCCGTCTAGATGAAATCGAGGC
CGAGATCGAAACACTTGAGGCGCAAATCGCTGAAGTGGAACAACAGCTATGTGATCCGTCCATTTATGGCGATTATGAAA
CAGTACAACGGTTATCGCAAGAAAACGAGGAACGAAAACGGCAAGTCGAAAAGTTATTGGCTGAATGGGAACAGCTTTAC
TCTTCACTCTAA

Upstream 100 bases:

>100_bases
AAAACAATCTCCTCCAATTATACACTATACACGATTTTTGTTTATCTGTCTTTGACCGTTTTGGCGACATACGTTAAACT
ATTCCGAGAGGTGAAACGAC

Downstream 100 bases:

>100_bases
CCGATAGCCCGCCCGTTATTTTGGCGGGCTGTTTTTAAGTTAGTCACATTATCCACAAAACAATTCACAATCACACCTAT
GAAATATAAGTTATTCACCA

Product: ABC transporter ATP-binding protein Uup

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 643; Mature: 643

Protein sequence:

>643_residues
MIILQVHQLTKYFGADLILSNIKLEVQSRDRIALVGRNGAGKSTLLKIIAGELSYDSGEIIKPSHIKIGYLAQNSGLDSS
RSIWDEMLEVFAPLLAIEKQLAALGSQLGDPDVLADPARYEKILKAYDELQEQYKEQGGYQYEADIRSVLHGLQFSSYDY
KTTLISSLSGGQRTRLALGKLLLSKPDLLILDEPTNHLDLETLSWLEQYLQAYPGAVLLVSHDRYFLDKVVTEVYELSNT
KLKRYTGNYSRYLEQRAEQYEQELKRYEKQQEEIARLQDFIQRNIARASTTKRAQSRRKQLEKMERLERPTGDGKSASFS
FTIERPSGHEVLTAEELAVGYGEGTPVIRQISFRITRGESVALVGPNGIGKSTLLKAVAQRLPVQAGKLRYGSNVQIGYY
DQNQAELSSNKRVLDELWDDYPDKTEKEIRTVLGNFLFSGDDVLKPVSALSGGEKARLALAKLMLQKANVLILDEPTNHL
DLDSKQVLEQALIDYPGTILFVSHDRYFINRIATKLFELSSDGLTEYLGDYDYYIAKKAEMCELERLDARPDKTQDSNES
SKSAYKQEKEEKKRQRQRQRRLDEIEAEIETLEAQIAEVEQQLCDPSIYGDYETVQRLSQENEERKRQVEKLLAEWEQLY
SSL

Sequences:

>Translated_643_residues
MIILQVHQLTKYFGADLILSNIKLEVQSRDRIALVGRNGAGKSTLLKIIAGELSYDSGEIIKPSHIKIGYLAQNSGLDSS
RSIWDEMLEVFAPLLAIEKQLAALGSQLGDPDVLADPARYEKILKAYDELQEQYKEQGGYQYEADIRSVLHGLQFSSYDY
KTTLISSLSGGQRTRLALGKLLLSKPDLLILDEPTNHLDLETLSWLEQYLQAYPGAVLLVSHDRYFLDKVVTEVYELSNT
KLKRYTGNYSRYLEQRAEQYEQELKRYEKQQEEIARLQDFIQRNIARASTTKRAQSRRKQLEKMERLERPTGDGKSASFS
FTIERPSGHEVLTAEELAVGYGEGTPVIRQISFRITRGESVALVGPNGIGKSTLLKAVAQRLPVQAGKLRYGSNVQIGYY
DQNQAELSSNKRVLDELWDDYPDKTEKEIRTVLGNFLFSGDDVLKPVSALSGGEKARLALAKLMLQKANVLILDEPTNHL
DLDSKQVLEQALIDYPGTILFVSHDRYFINRIATKLFELSSDGLTEYLGDYDYYIAKKAEMCELERLDARPDKTQDSNES
SKSAYKQEKEEKKRQRQRQRRLDEIEAEIETLEAQIAEVEQQLCDPSIYGDYETVQRLSQENEERKRQVEKLLAEWEQLY
SSL
>Mature_643_residues
MIILQVHQLTKYFGADLILSNIKLEVQSRDRIALVGRNGAGKSTLLKIIAGELSYDSGEIIKPSHIKIGYLAQNSGLDSS
RSIWDEMLEVFAPLLAIEKQLAALGSQLGDPDVLADPARYEKILKAYDELQEQYKEQGGYQYEADIRSVLHGLQFSSYDY
KTTLISSLSGGQRTRLALGKLLLSKPDLLILDEPTNHLDLETLSWLEQYLQAYPGAVLLVSHDRYFLDKVVTEVYELSNT
KLKRYTGNYSRYLEQRAEQYEQELKRYEKQQEEIARLQDFIQRNIARASTTKRAQSRRKQLEKMERLERPTGDGKSASFS
FTIERPSGHEVLTAEELAVGYGEGTPVIRQISFRITRGESVALVGPNGIGKSTLLKAVAQRLPVQAGKLRYGSNVQIGYY
DQNQAELSSNKRVLDELWDDYPDKTEKEIRTVLGNFLFSGDDVLKPVSALSGGEKARLALAKLMLQKANVLILDEPTNHL
DLDSKQVLEQALIDYPGTILFVSHDRYFINRIATKLFELSSDGLTEYLGDYDYYIAKKAEMCELERLDARPDKTQDSNES
SKSAYKQEKEEKKRQRQRQRRLDEIEAEIETLEAQIAEVEQQLCDPSIYGDYETVQRLSQENEERKRQVEKLLAEWEQLY
SSL

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI27881506, Length=543, Percent_Identity=34.622467771639, Blast_Score=275, Evalue=1e-73,
Organism=Homo sapiens, GI10947137, Length=543, Percent_Identity=34.622467771639, Blast_Score=274, Evalue=2e-73,
Organism=Homo sapiens, GI148612853, Length=532, Percent_Identity=32.3308270676692, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI10947135, Length=530, Percent_Identity=31.6981132075472, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI69354671, Length=530, Percent_Identity=31.6981132075472, Blast_Score=209, Evalue=5e-54,
Organism=Homo sapiens, GI90421313, Length=201, Percent_Identity=32.8358208955224, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1789751, Length=611, Percent_Identity=33.8788870703764, Blast_Score=338, Evalue=6e-94,
Organism=Escherichia coli, GI1787041, Length=540, Percent_Identity=33.3333333333333, Blast_Score=312, Evalue=5e-86,
Organism=Escherichia coli, GI1787182, Length=658, Percent_Identity=32.6747720364742, Blast_Score=303, Evalue=3e-83,
Organism=Escherichia coli, GI2367384, Length=529, Percent_Identity=34.9716446124764, Blast_Score=298, Evalue=8e-82,
Organism=Escherichia coli, GI1788165, Length=184, Percent_Identity=28.804347826087, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17555318, Length=532, Percent_Identity=32.1428571428571, Blast_Score=260, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI17553372, Length=527, Percent_Identity=33.3965844402277, Blast_Score=244, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI17559834, Length=538, Percent_Identity=30.6691449814126, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI212646699, Length=279, Percent_Identity=25.8064516129032, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71992285, Length=192, Percent_Identity=30.7291666666667, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25146777, Length=290, Percent_Identity=24.4827586206897, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17569143, Length=266, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=541, Percent_Identity=31.9778188539741, Blast_Score=256, Evalue=7e-69,
Organism=Saccharomyces cerevisiae, GI6320874, Length=550, Percent_Identity=33.4545454545455, Blast_Score=244, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6325030, Length=392, Percent_Identity=28.0612244897959, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6324314, Length=393, Percent_Identity=25.1908396946565, Blast_Score=113, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6323278, Length=241, Percent_Identity=27.8008298755187, Blast_Score=107, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6323217, Length=217, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24666836, Length=541, Percent_Identity=33.641404805915, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24642252, Length=536, Percent_Identity=33.5820895522388, Blast_Score=271, Evalue=1e-72,
Organism=Drosophila melanogaster, GI18859989, Length=536, Percent_Identity=33.5820895522388, Blast_Score=271, Evalue=1e-72,
Organism=Drosophila melanogaster, GI24641342, Length=532, Percent_Identity=32.3308270676692, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI28574259, Length=291, Percent_Identity=23.0240549828179, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281361582, Length=296, Percent_Identity=24.3243243243243, Blast_Score=67, Evalue=5e-11,
Organism=Drosophila melanogaster, GI45552437, Length=289, Percent_Identity=22.8373702422145, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24585557, Length=289, Percent_Identity=22.8373702422145, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 73346; Mature: 73346

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILQVHQLTKYFGADLILSNIKLEVQSRDRIALVGRNGAGKSTLLKIIAGELSYDSGEI
CEEEEHHHHHHHHHHHHHHHHCEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCC
IKPSHIKIGYLAQNSGLDSSRSIWDEMLEVFAPLLAIEKQLAALGSQLGDPDVLADPARY
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
EKILKAYDELQEQYKEQGGYQYEADIRSVLHGLQFSSYDYKTTLISSLSGGQRTRLALGK
HHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHH
LLLSKPDLLILDEPTNHLDLETLSWLEQYLQAYPGAVLLVSHDRYFLDKVVTEVYELSNT
HHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCC
KLKRYTGNYSRYLEQRAEQYEQELKRYEKQQEEIARLQDFIQRNIARASTTKRAQSRRKQ
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEKMERLERPTGDGKSASFSFTIERPSGHEVLTAEELAVGYGEGTPVIRQISFRITRGES
HHHHHHHCCCCCCCCCCEEEEEEECCCCCCEEEHHHHHHCCCCCCHHHHHHEEEEECCCE
VALVGPNGIGKSTLLKAVAQRLPVQAGKLRYGSNVQIGYYDQNQAELSSNKRVLDELWDD
EEEECCCCCCHHHHHHHHHHHCCCCCCCEECCCCCEEEEECCCHHHHHCCHHHHHHHHCC
YPDKTEKEIRTVLGNFLFSGDDVLKPVSALSGGEKARLALAKLMLQKANVLILDEPTNHL
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCCC
DLDSKQVLEQALIDYPGTILFVSHDRYFINRIATKLFELSSDGLTEYLGDYDYYIAKKAE
CCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHCCHH
MCELERLDARPDKTQDSNESSKSAYKQEKEEKKRQRQRQRRLDEIEAEIETLEAQIAEVE
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQLCDPSIYGDYETVQRLSQENEERKRQVEKLLAEWEQLYSSL
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIILQVHQLTKYFGADLILSNIKLEVQSRDRIALVGRNGAGKSTLLKIIAGELSYDSGEI
CEEEEHHHHHHHHHHHHHHHHCEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCC
IKPSHIKIGYLAQNSGLDSSRSIWDEMLEVFAPLLAIEKQLAALGSQLGDPDVLADPARY
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
EKILKAYDELQEQYKEQGGYQYEADIRSVLHGLQFSSYDYKTTLISSLSGGQRTRLALGK
HHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHH
LLLSKPDLLILDEPTNHLDLETLSWLEQYLQAYPGAVLLVSHDRYFLDKVVTEVYELSNT
HHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCC
KLKRYTGNYSRYLEQRAEQYEQELKRYEKQQEEIARLQDFIQRNIARASTTKRAQSRRKQ
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEKMERLERPTGDGKSASFSFTIERPSGHEVLTAEELAVGYGEGTPVIRQISFRITRGES
HHHHHHHCCCCCCCCCCEEEEEEECCCCCCEEEHHHHHHCCCCCCHHHHHHEEEEECCCE
VALVGPNGIGKSTLLKAVAQRLPVQAGKLRYGSNVQIGYYDQNQAELSSNKRVLDELWDD
EEEECCCCCCHHHHHHHHHHHCCCCCCCEECCCCCEEEEECCCHHHHHCCHHHHHHHHCC
YPDKTEKEIRTVLGNFLFSGDDVLKPVSALSGGEKARLALAKLMLQKANVLILDEPTNHL
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCCC
DLDSKQVLEQALIDYPGTILFVSHDRYFINRIATKLFELSSDGLTEYLGDYDYYIAKKAE
CCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHCCHH
MCELERLDARPDKTQDSNESSKSAYKQEKEEKKRQRQRQRRLDEIEAEIETLEAQIAEVE
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQLCDPSIYGDYETVQRLSQENEERKRQVEKLLAEWEQLYSSL
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]