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The map label for this gene is recD [H]

Identifier: 126696547

GI number: 126696547

Start: 1023406

End: 1025109

Strand: Reverse

Name: recD [H]

Synonym: P9301_12091

Alternate gene names: 126696547

Gene position: 1025109-1023406 (Counterclockwise)

Preceding gene: 126696548

Following gene: 126696546

Centisome position: 62.44

GC content: 23.83

Gene sequence:

>1704_bases
ATGACTAAAACTTCCACTGATATTGAAAAGTTCCAATACGATCATATATTTAATTTAATTTTAGGTATTTTCAAATTTAG
TGAAAAAAAATATGGAAATTTCGTAAAAGATGTAATAAGAATTTTATTAGAGTTTGAAAAAAATGGTGAAACTATTATTG
ATGTTGATAATAGTTTAATAATCTTTGAATTATTAGAGGATGGCTGGCCCAATAAACATATAGATGTTTTAAAAAATTTA
GGTTTGATTGGTTCCCTTGATTCTCCATTCGTATTAGTAAATAGAAAATTATCCTTATCAAAATGGTCAAAAAAGATAGA
AAGAGTTATTAATTTATTTATAAAAAAAATAGATACCGATAATTTAATGAACTCAATAATTTATAAAGATGATAATAAAA
TTGATCAAATTAAAAATATATTTAAATATTCAAACTTAGTTTTCCTTCAAGGAGGACCAGGCACGGGTAAAACCACTTTA
ATAATAAAGTTAATACTAGAACTGCTTCAAATTGATAACTTTTTAAATATTGGTTTGTCTGCTCCAACTGGTAAAGCTAC
AGCTCGTTTAAAAGAAGCCCTTAATGATAAAAAAAATATTTCCTTTAGCAAATTTCTAGATCAGATAGAATTTCAAACTT
TACATAGATGGATTTTAAATTCTAAAAATAAATCTCTTACTTTGAAATTTAAACTAAAAGAGCTTGATATTTTTATAATT
GATGAAATGTCAATGGTTAATATCGATTTGATTGAATCAGTTTTAAATTTGCTAGCAAAGGATTGTAAAATTATTTTAGT
TGGTGATAAAAATCAATTGTCTCCAGTAAATAACTGTTCTATATGGAATTATTTGTTTGAATATTCCGACAATAGTTCAA
TTAAATCTTGTGTAGTAAATTTAGAAAAAACTTATAGAAACATTGGAGATATAGCATTAATTAGTAGTTTAATATTTAAT
AATGATTTTTCTTTACTTAATCAAAAGATAAAAGAATTAGAAAAAGATAATAATTCAAAAGAAATTACTATTTCAAAGAG
TAGAAAAAAAGATATTCCAAAAGATCTATTATTTTCGATTACAAGTCATCTAAAACAGTTAAATATTTCAACTTCAAATT
TAAGTAAAAAAAAATATATATTTGATAAGTGTATTGATAATTTGTTGCTTAATGAAAAAGATTTAGTAGATAAGATATTT
CTGGATTTACAAAGTCACTTAATTTTATGCGAAAAAAATTCCGGAATATGGAGTGTTGAATATTTGAATGAAATTGTTTT
TGGTCAAAAAAAACCCTATGACCTTAAAACTCTTAAAGAGGGTATTCCGATCATGTGTACAAAAAATAATAATGAACTAG
GATTGTCAAATGGGGATATCGGAGTACTTATAGGTTTAGAAAATAAAAGAAAATATCTTTTTAGAAAATTTAATGATAAT
AACGAAGAAATTGTCACATTAATTGATCCATCTAATTTAGAAAATGTTGTACCAGCAATAGCCATTACTATTCATAAATC
TCAAGGAAGTGAATCTGAAAAAGTAAACATTTTGTGGTCCCAAAACTATAGAAGAAATCAATATGCTGTAAAAGAAAAAA
AAGATAGTCAAAATAGCTTTTGCAGAGATAATTTTGAAAGAAGGTTATTTTATACTGCTGTTACAAGAGCGAAAAAATCT
TTAAATATATATTATTTAAATTAA

Upstream 100 bases:

>100_bases
GAATTATTTGAAAAGTCTAAGTCTGAAGATATATCTCCAGGTATTTTTATTAGCAAAGCACCTTTAAAAAGAATTAATTA
TTTAGATAACCTTTTTTAAA

Downstream 100 bases:

>100_bases
ATTTTATTTTTGAGAAATTAGTAATATCTTAACCCCAAGATGTTAGATTAATATTTCGGCTCTGTAAGGCTAATCAACAA
TTTATGTCAATTTAGATATT

Product: exodeoxyribonuclease V 67 kD polypeptide

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 567; Mature: 566

Protein sequence:

>567_residues
MTKTSTDIEKFQYDHIFNLILGIFKFSEKKYGNFVKDVIRILLEFEKNGETIIDVDNSLIIFELLEDGWPNKHIDVLKNL
GLIGSLDSPFVLVNRKLSLSKWSKKIERVINLFIKKIDTDNLMNSIIYKDDNKIDQIKNIFKYSNLVFLQGGPGTGKTTL
IIKLILELLQIDNFLNIGLSAPTGKATARLKEALNDKKNISFSKFLDQIEFQTLHRWILNSKNKSLTLKFKLKELDIFII
DEMSMVNIDLIESVLNLLAKDCKIILVGDKNQLSPVNNCSIWNYLFEYSDNSSIKSCVVNLEKTYRNIGDIALISSLIFN
NDFSLLNQKIKELEKDNNSKEITISKSRKKDIPKDLLFSITSHLKQLNISTSNLSKKKYIFDKCIDNLLLNEKDLVDKIF
LDLQSHLILCEKNSGIWSVEYLNEIVFGQKKPYDLKTLKEGIPIMCTKNNNELGLSNGDIGVLIGLENKRKYLFRKFNDN
NEEIVTLIDPSNLENVVPAIAITIHKSQGSESEKVNILWSQNYRRNQYAVKEKKDSQNSFCRDNFERRLFYTAVTRAKKS
LNIYYLN

Sequences:

>Translated_567_residues
MTKTSTDIEKFQYDHIFNLILGIFKFSEKKYGNFVKDVIRILLEFEKNGETIIDVDNSLIIFELLEDGWPNKHIDVLKNL
GLIGSLDSPFVLVNRKLSLSKWSKKIERVINLFIKKIDTDNLMNSIIYKDDNKIDQIKNIFKYSNLVFLQGGPGTGKTTL
IIKLILELLQIDNFLNIGLSAPTGKATARLKEALNDKKNISFSKFLDQIEFQTLHRWILNSKNKSLTLKFKLKELDIFII
DEMSMVNIDLIESVLNLLAKDCKIILVGDKNQLSPVNNCSIWNYLFEYSDNSSIKSCVVNLEKTYRNIGDIALISSLIFN
NDFSLLNQKIKELEKDNNSKEITISKSRKKDIPKDLLFSITSHLKQLNISTSNLSKKKYIFDKCIDNLLLNEKDLVDKIF
LDLQSHLILCEKNSGIWSVEYLNEIVFGQKKPYDLKTLKEGIPIMCTKNNNELGLSNGDIGVLIGLENKRKYLFRKFNDN
NEEIVTLIDPSNLENVVPAIAITIHKSQGSESEKVNILWSQNYRRNQYAVKEKKDSQNSFCRDNFERRLFYTAVTRAKKS
LNIYYLN
>Mature_566_residues
TKTSTDIEKFQYDHIFNLILGIFKFSEKKYGNFVKDVIRILLEFEKNGETIIDVDNSLIIFELLEDGWPNKHIDVLKNLG
LIGSLDSPFVLVNRKLSLSKWSKKIERVINLFIKKIDTDNLMNSIIYKDDNKIDQIKNIFKYSNLVFLQGGPGTGKTTLI
IKLILELLQIDNFLNIGLSAPTGKATARLKEALNDKKNISFSKFLDQIEFQTLHRWILNSKNKSLTLKFKLKELDIFIID
EMSMVNIDLIESVLNLLAKDCKIILVGDKNQLSPVNNCSIWNYLFEYSDNSSIKSCVVNLEKTYRNIGDIALISSLIFNN
DFSLLNQKIKELEKDNNSKEITISKSRKKDIPKDLLFSITSHLKQLNISTSNLSKKKYIFDKCIDNLLLNEKDLVDKIFL
DLQSHLILCEKNSGIWSVEYLNEIVFGQKKPYDLKTLKEGIPIMCTKNNNELGLSNGDIGVLIGLENKRKYLFRKFNDNN
EEIVTLIDPSNLENVVPAIAITIHKSQGSESEKVNILWSQNYRRNQYAVKEKKDSQNSFCRDNFERRLFYTAVTRAKKSL
NIYYLN

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=449, Percent_Identity=26.2806236080178, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 65439; Mature: 65307

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTSTDIEKFQYDHIFNLILGIFKFSEKKYGNFVKDVIRILLEFEKNGETIIDVDNSLI
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEE
IFELLEDGWPNKHIDVLKNLGLIGSLDSPFVLVNRKLSLSKWSKKIERVINLFIKKIDTD
EEEEHHCCCCCCHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCHH
NLMNSIIYKDDNKIDQIKNIFKYSNLVFLQGGPGTGKTTLIIKLILELLQIDNFLNIGLS
HHHHHHEECCCCHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHCCHHCCCCC
APTGKATARLKEALNDKKNISFSKFLDQIEFQTLHRWILNSKNKSLTLKFKLKELDIFII
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEEEE
DEMSMVNIDLIESVLNLLAKDCKIILVGDKNQLSPVNNCSIWNYLFEYSDNSSIKSCVVN
CCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHH
LEKTYRNIGDIALISSLIFNNDFSLLNQKIKELEKDNNSKEITISKSRKKDIPKDLLFSI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHH
TSHLKQLNISTSNLSKKKYIFDKCIDNLLLNEKDLVDKIFLDLQSHLILCEKNSGIWSVE
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCEEEEECCCCEEEHH
YLNEIVFGQKKPYDLKTLKEGIPIMCTKNNNELGLSNGDIGVLIGLENKRKYLFRKFNDN
HHHHHHCCCCCCCCHHHHHCCCCEEEECCCCEECCCCCCEEEEEECCCCHHHHHHHCCCC
NEEIVTLIDPSNLENVVPAIAITIHKSQGSESEKVNILWSQNYRRNQYAVKEKKDSQNSF
CCEEEEEECCCCCHHHCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCHHHHCCCCCCCH
CRDNFERRLFYTAVTRAKKSLNIYYLN
HHHHHHHHHHHHHHHHHHHCCEEEEEC
>Mature Secondary Structure 
TKTSTDIEKFQYDHIFNLILGIFKFSEKKYGNFVKDVIRILLEFEKNGETIIDVDNSLI
CCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEE
IFELLEDGWPNKHIDVLKNLGLIGSLDSPFVLVNRKLSLSKWSKKIERVINLFIKKIDTD
EEEEHHCCCCCCHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCHH
NLMNSIIYKDDNKIDQIKNIFKYSNLVFLQGGPGTGKTTLIIKLILELLQIDNFLNIGLS
HHHHHHEECCCCHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHCCHHCCCCC
APTGKATARLKEALNDKKNISFSKFLDQIEFQTLHRWILNSKNKSLTLKFKLKELDIFII
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEEEE
DEMSMVNIDLIESVLNLLAKDCKIILVGDKNQLSPVNNCSIWNYLFEYSDNSSIKSCVVN
CCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHH
LEKTYRNIGDIALISSLIFNNDFSLLNQKIKELEKDNNSKEITISKSRKKDIPKDLLFSI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHH
TSHLKQLNISTSNLSKKKYIFDKCIDNLLLNEKDLVDKIFLDLQSHLILCEKNSGIWSVE
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCEEEEECCCCEEEHH
YLNEIVFGQKKPYDLKTLKEGIPIMCTKNNNELGLSNGDIGVLIGLENKRKYLFRKFNDN
HHHHHHCCCCCCCCHHHHHCCCCEEEECCCCEECCCCCCEEEEEECCCCHHHHHHHCCCC
NEEIVTLIDPSNLENVVPAIAITIHKSQGSESEKVNILWSQNYRRNQYAVKEKKDSQNSF
CCEEEEEECCCCCHHHCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCHHHHCCCCCCCH
CRDNFERRLFYTAVTRAKKSLNIYYLN
HHHHHHHHHHHHHHHHHHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]