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The map label for this gene is hslO

Identifier: 126696056

GI number: 126696056

Start: 639245

End: 640153

Strand: Reverse

Name: hslO

Synonym: P9301_07181

Alternate gene names: 126696056

Gene position: 640153-639245 (Counterclockwise)

Preceding gene: 126696057

Following gene: 126696052

Centisome position: 38.99

GC content: 33.11

Gene sequence:

>909_bases
ATGCAGGATAGGATAGTACGAGCCACTGCAGCAAATGGTGGAATAAGATTAGTTGCTGTCTTAACAACAGAATCTTCCCT
AGAAGCCAAAAAAAGACACGATCTTTCTTATCTAACCACCTGCATCTTAGGGAGAGCATTTAGTGCCTCACTGCTTTTAG
CAAGTTCAATGAAGATAATGCATGGAAGAGTAACCCTAAGAGTACGTTCTGACGGACCTTTGAAGGGATTGCTGGTTGAT
GCAGGTAGAGACGGTAAAGTCAGAGGATATGTAGGAAATCCTGATTTAGAATTGGATCTAGTCAAAATAGATAGTAATAA
ATATTCTTTTGATTTCACAAAAGCATTAGGTACTGGATATTTAAATGTTATTAGAGATAGCGGAATTGGAGAACCCTTTA
CAAGCACAGTTGAATTAGTAAATGGGAATATTGCAGAAGACTTAGCTTCATATTTATATCATTCAGAACAAACTCCTTCT
GCTGTATTTATTGGAGAAAAAATTCAAAATCAAGGAATTATTTGTAGTGGTGGATTATTAGCTCAAGTTTTACCTAAAAA
AGATACTGACCCTTTACTAGTCTCACTACTTGAAGAAAGATGTAAAGAAGTAAATTCTTTTAGCGAAGATCTATTTCAAT
CAAAAGATAATCTTCTTTCCTTGATAAAAAAAATATTTCCTGATATCGACGATGAATCAATATCTGAAAAAGCTCGTTCA
CAAGAAGTTAGTTTTAAATGCAAGTGTTCTAAACAAAGAAGTTTAAATGCAATGAATATGCTTGATAAGAGCGAGTTGGA
GGACATCCTCAAGAAAGATGGCAATGCAGAATTAGTATGTGAATTTTGTAAGAATAAATATCTTATAAATTATGAAGAAA
TTAAATTGATGATAGAAAATCAATCATAA

Upstream 100 bases:

>100_bases
ATTATTATTGTTACTCATGAACCTGAAATGTTTGAGGGAATTACTTCTAGGATATTATTCTTGGAAAAAGGGAAAATCAA
AAATTTTATGAAAGAAAATC

Downstream 100 bases:

>100_bases
GAAAATTACGCCTAGCCATAAAATAACCATGGCTGGAATACTTTGAATTTTTTGTATCGATAGAGAATTATTTGAAATTT
CCTGAATGAAAGAATTATTT

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MQDRIVRATAANGGIRLVAVLTTESSLEAKKRHDLSYLTTCILGRAFSASLLLASSMKIMHGRVTLRVRSDGPLKGLLVD
AGRDGKVRGYVGNPDLELDLVKIDSNKYSFDFTKALGTGYLNVIRDSGIGEPFTSTVELVNGNIAEDLASYLYHSEQTPS
AVFIGEKIQNQGIICSGGLLAQVLPKKDTDPLLVSLLEERCKEVNSFSEDLFQSKDNLLSLIKKIFPDIDDESISEKARS
QEVSFKCKCSKQRSLNAMNMLDKSELEDILKKDGNAELVCEFCKNKYLINYEEIKLMIENQS

Sequences:

>Translated_302_residues
MQDRIVRATAANGGIRLVAVLTTESSLEAKKRHDLSYLTTCILGRAFSASLLLASSMKIMHGRVTLRVRSDGPLKGLLVD
AGRDGKVRGYVGNPDLELDLVKIDSNKYSFDFTKALGTGYLNVIRDSGIGEPFTSTVELVNGNIAEDLASYLYHSEQTPS
AVFIGEKIQNQGIICSGGLLAQVLPKKDTDPLLVSLLEERCKEVNSFSEDLFQSKDNLLSLIKKIFPDIDDESISEKARS
QEVSFKCKCSKQRSLNAMNMLDKSELEDILKKDGNAELVCEFCKNKYLINYEEIKLMIENQS
>Mature_302_residues
MQDRIVRATAANGGIRLVAVLTTESSLEAKKRHDLSYLTTCILGRAFSASLLLASSMKIMHGRVTLRVRSDGPLKGLLVD
AGRDGKVRGYVGNPDLELDLVKIDSNKYSFDFTKALGTGYLNVIRDSGIGEPFTSTVELVNGNIAEDLASYLYHSEQTPS
AVFIGEKIQNQGIICSGGLLAQVLPKKDTDPLLVSLLEERCKEVNSFSEDLFQSKDNLLSLIKKIFPDIDDESISEKARS
QEVSFKCKCSKQRSLNAMNMLDKSELEDILKKDGNAELVCEFCKNKYLINYEEIKLMIENQS

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=303, Percent_Identity=24.0924092409241, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_PROM0 (A3PC66)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001090942.1
- ProteinModelPortal:   A3PC66
- SMR:   A3PC66
- STRING:   A3PC66
- GeneID:   4912641
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_07181
- eggNOG:   COG1281
- HOGENOM:   HBG286231
- OMA:   VMLGRAM
- ProtClustDB:   PRK00114
- BioCyc:   PMAR167546:P9301ORF_0732-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 33458; Mature: 33458

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDRIVRATAANGGIRLVAVLTTESSLEAKKRHDLSYLTTCILGRAFSASLLLASSMKIM
CCCCEEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
HGRVTLRVRSDGPLKGLLVDAGRDGKVRGYVGNPDLELDLVKIDSNKYSFDFTKALGTGY
ECEEEEEECCCCCEEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCEEEEHHHHHCCHH
LNVIRDSGIGEPFTSTVELVNGNIAEDLASYLYHSEQTPSAVFIGEKIQNQGIICSGGLL
HHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEHHHCCCCEEECCCHH
AQVLPKKDTDPLLVSLLEERCKEVNSFSEDLFQSKDNLLSLIKKIFPDIDDESISEKARS
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHH
QEVSFKCKCSKQRSLNAMNMLDKSELEDILKKDGNAELVCEFCKNKYLINYEEIKLMIEN
CCCEEEEECCHHHCCHHHHHCCHHHHHHHHHCCCCHHHHHHHHCCCEEEEHHHEEEEEEC
QS
CC
>Mature Secondary Structure
MQDRIVRATAANGGIRLVAVLTTESSLEAKKRHDLSYLTTCILGRAFSASLLLASSMKIM
CCCCEEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
HGRVTLRVRSDGPLKGLLVDAGRDGKVRGYVGNPDLELDLVKIDSNKYSFDFTKALGTGY
ECEEEEEECCCCCEEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCEEEEHHHHHCCHH
LNVIRDSGIGEPFTSTVELVNGNIAEDLASYLYHSEQTPSAVFIGEKIQNQGIICSGGLL
HHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEHHHCCCCEEECCCHH
AQVLPKKDTDPLLVSLLEERCKEVNSFSEDLFQSKDNLLSLIKKIFPDIDDESISEKARS
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHH
QEVSFKCKCSKQRSLNAMNMLDKSELEDILKKDGNAELVCEFCKNKYLINYEEIKLMIEN
CCCEEEEECCHHHCCHHHHHCCHHHHHHHHHCCCCHHHHHHHHCCCEEEEHHHEEEEEEC
QS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA