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The map label for this gene is pilC [H]

Identifier: 126696027

GI number: 126696027

Start: 611413

End: 612774

Strand: Reverse

Name: pilC [H]

Synonym: P9301_06891

Alternate gene names: 126696027

Gene position: 612774-611413 (Counterclockwise)

Preceding gene: 126696028

Following gene: 126696025

Centisome position: 37.32

GC content: 31.5

Gene sequence:

>1362_bases
GTGGATTATAGATACATCGAAAACGCAAAATTAAGAAGGCTTATGCAAAAAGCTAGGCATAAAAGAAAAGTGCTTAATAA
TCCAAATAGAATTCCAGAACATAAAAACGCGAGAATCACTCAAAAATATAAAAACGTTATACCTATACCTGCAAAAAATC
AAAATTTAAGAAAAAAAGAAAAAAATAAACTTTCAATTTTGAAAACTTACGTCGAATTGAAAATACAAGAAAGAAAAGAA
TTTATCGAGGGTGACATGACTTCACTAAGAAATAAAAAAAAGATATTAAAGCCAAGGTTAATGGAGGGAAGAAAATTAAA
AAGTCCTCCAATAAAAGATTTAGCAGTTGCAACAAAACAGCTTTCTTCGATGATTAGAACAGGGTTACCTTTATTAGAAT
CCCTAAACATAATTGCAGATACATCTGAAAATATATCCATAAGATACTCATTTAAAGAGATAGCCTCAGGCATAAGCAAA
GGTTCCACCATGTCTGAAATGTTAGATAAATATCCAGAAGTATTTAATGAAATGTATCGAGCGCTTGTAAGCGCCGGAGA
AACTGCTGGATTATTGCCAAACACTTTAGATCGCCAAGCAAAATTATTAGAAAGTCTTGCAAAAATCAAGGGTCAGATAA
AAAGCGCTTTAGCATATCCTTCAGCTATAGCGATACTTACAGTAGTAATAGTTTTTATAATGATGCTTTTTGTTATTCCA
ATTTTTGTAGATATTTATGATCAATCAGGGGCCCCATTGCCTGGGATTACTCAATTTTTAATTAACTTATCAGATCAACT
AAGAACAATTGAATTTTATTTCAAAGCAGTTCCATCTGGGTTTGCTATTTATCTTTTTTATAAATATTTATCAAGTAGAT
CTTCAGTTATTTGGTGGTATGACAAAACTCTTCTCCAATTACCTATCACAAAAGACTTAGTAACAAAATCATGTTTAGCA
AATTTTTCAAGAACCTTATCTTCATTAAATAGTGCAGGGGTTCCAATTTTAGAGTCTTTAACAATCGCTAAGAAAACTTT
GAAAAATAGGATTTTTACCAGGATCATAGAAAATGCTTATTACGATATCCAAGCAGGTAATCCCATGCACAAAGCTTTTG
ATAAAGAGTCCGTAATTCCAGTAATGTTTACATCAATGTTTAGGATAGGAGAAGAGACAGGTGAGCTAAGTGAAATGATT
ACAAAACTAGCTGATTTTTATGAAGATGAAGTCTCTTCAAGCGTCAAAAGCTTAACTTCAATAATGGAACCTTTAATGAT
TATATTCGTAGCTGTTTTTGTAGGAATCATTCTAATTGCTATGTATTTACCTATGTTCAGTATGATGTCTACTGTGGGGT
AA

Upstream 100 bases:

>100_bases
ATAAATGTAATAGGCCAAATGTTTTGAAAGGTTTGCTTGAAGAAATTAATTCTGAGATGCCAACATAAATTGATATGAAC
TTAAATACTACAAAATAATT

Downstream 100 bases:

>100_bases
ATCCTTGTATAATTTATAAAAATAATATATCTAAAAATATCTCATTGCCAAAGTACCAAACAAGCAATCCAGACAAAGCT
AAAAAAATCCCAAAAGGTAT

Product: Type II secretory pathway component PulF-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MDYRYIENAKLRRLMQKARHKRKVLNNPNRIPEHKNARITQKYKNVIPIPAKNQNLRKKEKNKLSILKTYVELKIQERKE
FIEGDMTSLRNKKKILKPRLMEGRKLKSPPIKDLAVATKQLSSMIRTGLPLLESLNIIADTSENISIRYSFKEIASGISK
GSTMSEMLDKYPEVFNEMYRALVSAGETAGLLPNTLDRQAKLLESLAKIKGQIKSALAYPSAIAILTVVIVFIMMLFVIP
IFVDIYDQSGAPLPGITQFLINLSDQLRTIEFYFKAVPSGFAIYLFYKYLSSRSSVIWWYDKTLLQLPITKDLVTKSCLA
NFSRTLSSLNSAGVPILESLTIAKKTLKNRIFTRIIENAYYDIQAGNPMHKAFDKESVIPVMFTSMFRIGEETGELSEMI
TKLADFYEDEVSSSVKSLTSIMEPLMIIFVAVFVGIILIAMYLPMFSMMSTVG

Sequences:

>Translated_453_residues
MDYRYIENAKLRRLMQKARHKRKVLNNPNRIPEHKNARITQKYKNVIPIPAKNQNLRKKEKNKLSILKTYVELKIQERKE
FIEGDMTSLRNKKKILKPRLMEGRKLKSPPIKDLAVATKQLSSMIRTGLPLLESLNIIADTSENISIRYSFKEIASGISK
GSTMSEMLDKYPEVFNEMYRALVSAGETAGLLPNTLDRQAKLLESLAKIKGQIKSALAYPSAIAILTVVIVFIMMLFVIP
IFVDIYDQSGAPLPGITQFLINLSDQLRTIEFYFKAVPSGFAIYLFYKYLSSRSSVIWWYDKTLLQLPITKDLVTKSCLA
NFSRTLSSLNSAGVPILESLTIAKKTLKNRIFTRIIENAYYDIQAGNPMHKAFDKESVIPVMFTSMFRIGEETGELSEMI
TKLADFYEDEVSSSVKSLTSIMEPLMIIFVAVFVGIILIAMYLPMFSMMSTVG
>Mature_453_residues
MDYRYIENAKLRRLMQKARHKRKVLNNPNRIPEHKNARITQKYKNVIPIPAKNQNLRKKEKNKLSILKTYVELKIQERKE
FIEGDMTSLRNKKKILKPRLMEGRKLKSPPIKDLAVATKQLSSMIRTGLPLLESLNIIADTSENISIRYSFKEIASGISK
GSTMSEMLDKYPEVFNEMYRALVSAGETAGLLPNTLDRQAKLLESLAKIKGQIKSALAYPSAIAILTVVIVFIMMLFVIP
IFVDIYDQSGAPLPGITQFLINLSDQLRTIEFYFKAVPSGFAIYLFYKYLSSRSSVIWWYDKTLLQLPITKDLVTKSCLA
NFSRTLSSLNSAGVPILESLTIAKKTLKNRIFTRIIENAYYDIQAGNPMHKAFDKESVIPVMFTSMFRIGEETGELSEMI
TKLADFYEDEVSSSVKSLTSIMEPLMIIFVAVFVGIILIAMYLPMFSMMSTVG

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=363, Percent_Identity=28.6501377410468, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1786295, Length=338, Percent_Identity=26.9230769230769, Blast_Score=134, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 51499; Mature: 51499

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYRYIENAKLRRLMQKARHKRKVLNNPNRIPEHKNARITQKYKNVIPIPAKNQNLRKKE
CCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHH
KNKLSILKTYVELKIQERKEFIEGDMTSLRNKKKILKPRLMEGRKLKSPPIKDLAVATKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LSSMIRTGLPLLESLNIIADTSENISIRYSFKEIASGISKGSTMSEMLDKYPEVFNEMYR
HHHHHHHCCHHHHHCHHHCCCCCCCEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ALVSAGETAGLLPNTLDRQAKLLESLAKIKGQIKSALAYPSAIAILTVVIVFIMMLFVIP
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
IFVDIYDQSGAPLPGITQFLINLSDQLRTIEFYFKAVPSGFAIYLFYKYLSSRSSVIWWY
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEE
DKTLLQLPITKDLVTKSCLANFSRTLSSLNSAGVPILESLTIAKKTLKNRIFTRIIENAY
CCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YDIQAGNPMHKAFDKESVIPVMFTSMFRIGEETGELSEMITKLADFYEDEVSSSVKSLTS
EECCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMEPLMIIFVAVFVGIILIAMYLPMFSMMSTVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDYRYIENAKLRRLMQKARHKRKVLNNPNRIPEHKNARITQKYKNVIPIPAKNQNLRKKE
CCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHH
KNKLSILKTYVELKIQERKEFIEGDMTSLRNKKKILKPRLMEGRKLKSPPIKDLAVATKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LSSMIRTGLPLLESLNIIADTSENISIRYSFKEIASGISKGSTMSEMLDKYPEVFNEMYR
HHHHHHHCCHHHHHCHHHCCCCCCCEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ALVSAGETAGLLPNTLDRQAKLLESLAKIKGQIKSALAYPSAIAILTVVIVFIMMLFVIP
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
IFVDIYDQSGAPLPGITQFLINLSDQLRTIEFYFKAVPSGFAIYLFYKYLSSRSSVIWWY
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEE
DKTLLQLPITKDLVTKSCLANFSRTLSSLNSAGVPILESLTIAKKTLKNRIFTRIIENAY
CCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YDIQAGNPMHKAFDKESVIPVMFTSMFRIGEETGELSEMITKLADFYEDEVSSSVKSLTS
EECCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMEPLMIIFVAVFVGIILIAMYLPMFSMMSTVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]