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The map label for this gene is zntA [H]

Identifier: 126695488

GI number: 126695488

Start: 138487

End: 140781

Strand: Reverse

Name: zntA [H]

Synonym: P9301_01501

Alternate gene names: 126695488

Gene position: 140781-138487 (Counterclockwise)

Preceding gene: 126695490

Following gene: 126695487

Centisome position: 8.57

GC content: 32.07

Gene sequence:

>2295_bases
ATGGAAAGCATTCAATTAAGGATTACAGGAATGAAGTGCGGAGGTTGTGTTAGTACTGTTGAAAAAATATTAAATAATTC
TGATGGTATTGAAAATGTTTCTGTAAACTTACTAACTGAAAGTGCATATTTTGAAATTACTCAGAAACATATCGAAATAG
AAGCAGTTCTCAAAAATTTAAAAGAAAATGGTTTCCCTTCAAAGATTTACATAAATGATTTTTCAAAAAAAATAAATAAG
GAAGAATTAGAAAAAAAAAAGAAGTGGAATAATCAATGGAAAAAACTAACTTTTGCTTTATTACTTTTATTATTTTCAGG
TTTAGGTCATCTAGCAGAGGGAAGATATATAAATTTTCCGATATTAGGTAATATTTTTTTTCACGCTTCATTAGCAACAT
TAGCTCTATTATTTCCTGGCAGAGAAATAATTATTAATGGGTTTAAATCATTTATTAAGAACCGTCCTGATATGGATTCT
CTAGTAGCTCTTGGAGTAACTAGCGCATATATAACAAGTCTTCTATCTTTAATATTTCCTGCCACTGGTTTTCCTTGTTT
TTTTAATGAACCAGTTATGTTGTTAGGTTTCATATTGATTGGGCGTTTCTTGGAGGAAAGAGCAAGATATCAAACTGGTT
CATCCATTGGAGAGTTATTAGATCTTCAACCTGAAATGGCAAATATCTATACAGAAGATAATCAAATAAAATCAATAAGG
GTAAACACTTTAAGACCTAATCAAGAGATTCAAGTTTTAGCAGGAGACAGAGTACCTGCTGACTGCATTGTTACTCAAGG
TAATTCATATGTTGATGTTTCACATATCACTGGAGAATCTAAACCTATCGAGGTAAAAGAAGGCGAAAATCTATCTAGTG
GATCTTTAAATCTTAATTCAACACTCAGACTTAAAGTACAAAAGGTCGGAGGGGATTCTTCTCTTGCAAAACTAGTAAAT
CTTATTGAGTCTGTAAACGCTAGAAAACCTCGCATTCAAAGAATTGCTGATGAAATTGCAGGCAAATTTACTTACTTTGT
ACTTATTTTTGCTACTTTAACCTTCTTCTTTTGGTGGCAAGGGGCAAGAAACATTTGGCCAGATTTATTAAGTCATAATC
ATCAATTCATCACTCACTCAAGCCATACACTTCATAGTTCGCTTGGTAGTAATGCTGAGAACTTCCTTAGTTTAGCCATT
CAATTGTCAATTGCTGTTTTAGTAATAGCTTGTCCTTGTGCATTAGGTTTAGCCACCCCAACTGTAATAACTGTCGCATC
AGGTAAAGCAGCAAAAAAGGGGGTTCTATTTAAAGGTGGGGACAAAATAGAAATGGCTTCAAAAATTAATCACATTATTT
TTGACAAGACAGGTACATTAACAAAAGGTAAGCCTTTCATCGTTGATTATAAAAATAATGATGATTATTCTTTTTTATTA
AAAGTAGCTGCCAGTTTAGAAAAGGAAAGCAGACATCCAATTGCAGATGCGTTAATTCAAGAAGCCAAAAAACAAAATTT
AAGTTTATTTCCAATAAAAAAAATTGTCACTCATTCAGGCCGGGGGATTTCTGGAGAACTAGAGTCAATTGATGGACTCA
TAAATATTGGAAATATTGAATGGCTACTAAGTAAAGGAATAATTATTGATAGTGATGCAAAAAAAGTAATTGAAAATGAA
GAGACAAAAACTAACACTATTATTGGAGTAAGTATTAAAGATAAATTATTAGGCTTTATCTTCCTAGGAGATTTACTCAG
AGATGATTCTATTAAAACAGTGCAAAATTTAAGAAAAAACAAATTTAAAATTAATATTTTAAGTGGAGATAGAAAACAAA
CGGTTTTAGCTTTAGCAAAAAAAATTGGTTTTAAAGAAGCAGAAGTAAAATGGGATCTTCTTCCTGAAATGAAGCTAAAG
ACTATAGAAAATTTAAAAATTGATAACAAAGTAGCAATGATTGGTGATGGTATTAATGATGTCCCTGCCTTAGCATCCTC
AGACTTAGGAATTGCGGTGGGATCAGGGACTCAAATAGCCAAGGCAAATGCAGATGTAGTCTTGATGGGAGATCAACTAA
ATGGATTACCCTACGCCTTAAATCTCGCAAAAAAAACTATAAGAAAAATAAAACAAAATCTAACATGGGCTTTTGGTTAC
AACTTACTAGCTATACCTATAGCCGCCGGCATTTTATTCCCTAAATACGGTATTCTTCTTACTCCCTCAATAGCAGCATT
ATTGATGGCTATTAGCTCTATTACAGTTGTAATTAATGCTTTATCTTTGGATTAA

Upstream 100 bases:

>100_bases
AATATAGTAATTTAAAAAATAACTATTTAAAAAGTCTATTACATTTATTATTATAGTTAAAAAATAGGCCGAGCATTAAT
TTGCTTCAACAGTGAAAAAT

Downstream 100 bases:

>100_bases
ATGAAAGGAAAATTTATCGTTATTGAGGGTATTGATGGATGTGGTAAAACTACCCAAATAGATGAACTATCTAAATGGCT
TCCTATTAGTGGTCTACTAA

Product: putative P-type ATPase transporter for copper

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 764; Mature: 764

Protein sequence:

>764_residues
MESIQLRITGMKCGGCVSTVEKILNNSDGIENVSVNLLTESAYFEITQKHIEIEAVLKNLKENGFPSKIYINDFSKKINK
EELEKKKKWNNQWKKLTFALLLLLFSGLGHLAEGRYINFPILGNIFFHASLATLALLFPGREIIINGFKSFIKNRPDMDS
LVALGVTSAYITSLLSLIFPATGFPCFFNEPVMLLGFILIGRFLEERARYQTGSSIGELLDLQPEMANIYTEDNQIKSIR
VNTLRPNQEIQVLAGDRVPADCIVTQGNSYVDVSHITGESKPIEVKEGENLSSGSLNLNSTLRLKVQKVGGDSSLAKLVN
LIESVNARKPRIQRIADEIAGKFTYFVLIFATLTFFFWWQGARNIWPDLLSHNHQFITHSSHTLHSSLGSNAENFLSLAI
QLSIAVLVIACPCALGLATPTVITVASGKAAKKGVLFKGGDKIEMASKINHIIFDKTGTLTKGKPFIVDYKNNDDYSFLL
KVAASLEKESRHPIADALIQEAKKQNLSLFPIKKIVTHSGRGISGELESIDGLINIGNIEWLLSKGIIIDSDAKKVIENE
ETKTNTIIGVSIKDKLLGFIFLGDLLRDDSIKTVQNLRKNKFKINILSGDRKQTVLALAKKIGFKEAEVKWDLLPEMKLK
TIENLKIDNKVAMIGDGINDVPALASSDLGIAVGSGTQIAKANADVVLMGDQLNGLPYALNLAKKTIRKIKQNLTWAFGY
NLLAIPIAAGILFPKYGILLTPSIAALLMAISSITVVINALSLD

Sequences:

>Translated_764_residues
MESIQLRITGMKCGGCVSTVEKILNNSDGIENVSVNLLTESAYFEITQKHIEIEAVLKNLKENGFPSKIYINDFSKKINK
EELEKKKKWNNQWKKLTFALLLLLFSGLGHLAEGRYINFPILGNIFFHASLATLALLFPGREIIINGFKSFIKNRPDMDS
LVALGVTSAYITSLLSLIFPATGFPCFFNEPVMLLGFILIGRFLEERARYQTGSSIGELLDLQPEMANIYTEDNQIKSIR
VNTLRPNQEIQVLAGDRVPADCIVTQGNSYVDVSHITGESKPIEVKEGENLSSGSLNLNSTLRLKVQKVGGDSSLAKLVN
LIESVNARKPRIQRIADEIAGKFTYFVLIFATLTFFFWWQGARNIWPDLLSHNHQFITHSSHTLHSSLGSNAENFLSLAI
QLSIAVLVIACPCALGLATPTVITVASGKAAKKGVLFKGGDKIEMASKINHIIFDKTGTLTKGKPFIVDYKNNDDYSFLL
KVAASLEKESRHPIADALIQEAKKQNLSLFPIKKIVTHSGRGISGELESIDGLINIGNIEWLLSKGIIIDSDAKKVIENE
ETKTNTIIGVSIKDKLLGFIFLGDLLRDDSIKTVQNLRKNKFKINILSGDRKQTVLALAKKIGFKEAEVKWDLLPEMKLK
TIENLKIDNKVAMIGDGINDVPALASSDLGIAVGSGTQIAKANADVVLMGDQLNGLPYALNLAKKTIRKIKQNLTWAFGY
NLLAIPIAAGILFPKYGILLTPSIAALLMAISSITVVINALSLD
>Mature_764_residues
MESIQLRITGMKCGGCVSTVEKILNNSDGIENVSVNLLTESAYFEITQKHIEIEAVLKNLKENGFPSKIYINDFSKKINK
EELEKKKKWNNQWKKLTFALLLLLFSGLGHLAEGRYINFPILGNIFFHASLATLALLFPGREIIINGFKSFIKNRPDMDS
LVALGVTSAYITSLLSLIFPATGFPCFFNEPVMLLGFILIGRFLEERARYQTGSSIGELLDLQPEMANIYTEDNQIKSIR
VNTLRPNQEIQVLAGDRVPADCIVTQGNSYVDVSHITGESKPIEVKEGENLSSGSLNLNSTLRLKVQKVGGDSSLAKLVN
LIESVNARKPRIQRIADEIAGKFTYFVLIFATLTFFFWWQGARNIWPDLLSHNHQFITHSSHTLHSSLGSNAENFLSLAI
QLSIAVLVIACPCALGLATPTVITVASGKAAKKGVLFKGGDKIEMASKINHIIFDKTGTLTKGKPFIVDYKNNDDYSFLL
KVAASLEKESRHPIADALIQEAKKQNLSLFPIKKIVTHSGRGISGELESIDGLINIGNIEWLLSKGIIIDSDAKKVIENE
ETKTNTIIGVSIKDKLLGFIFLGDLLRDDSIKTVQNLRKNKFKINILSGDRKQTVLALAKKIGFKEAEVKWDLLPEMKLK
TIENLKIDNKVAMIGDGINDVPALASSDLGIAVGSGTQIAKANADVVLMGDQLNGLPYALNLAKKTIRKIKQNLTWAFGY
NLLAIPIAAGILFPKYGILLTPSIAALLMAISSITVVINALSLD

Specific function: Involved in copper transport [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HMA domain [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=813, Percent_Identity=32.4723247232472, Blast_Score=385, Evalue=1e-107,
Organism=Homo sapiens, GI115529486, Length=842, Percent_Identity=28.8598574821853, Blast_Score=349, Evalue=5e-96,
Organism=Homo sapiens, GI55743073, Length=578, Percent_Identity=31.1418685121107, Blast_Score=266, Evalue=4e-71,
Organism=Escherichia coli, GI1786691, Length=774, Percent_Identity=31.0077519379845, Blast_Score=362, Evalue=1e-101,
Organism=Escherichia coli, GI1789879, Length=726, Percent_Identity=28.6501377410468, Blast_Score=236, Evalue=4e-63,
Organism=Escherichia coli, GI1786914, Length=477, Percent_Identity=26.4150943396226, Blast_Score=108, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17556548, Length=803, Percent_Identity=30.2615193026152, Blast_Score=305, Evalue=6e-83,
Organism=Saccharomyces cerevisiae, GI6320475, Length=693, Percent_Identity=33.9105339105339, Blast_Score=313, Evalue=9e-86,
Organism=Saccharomyces cerevisiae, GI6319772, Length=650, Percent_Identity=30, Blast_Score=276, Evalue=8e-75,
Organism=Saccharomyces cerevisiae, GI6325221, Length=581, Percent_Identity=22.8915662650602, Blast_Score=107, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6321430, Length=581, Percent_Identity=22.3752151462995, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321271, Length=188, Percent_Identity=28.7234042553192, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221329854, Length=588, Percent_Identity=29.0816326530612, Blast_Score=209, Evalue=8e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121
- InterPro:   IPR000150 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase [H]

EC number: =3.6.3.4 [H]

Molecular weight: Translated: 84008; Mature: 84008

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS00154 ATPASE_E1_E2 ; PS01047 HMA_1 ; PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESIQLRITGMKCGGCVSTVEKILNNSDGIENVSVNLLTESAYFEITQKHIEIEAVLKNL
CCCEEEEEEEEECCHHHHHHHHHHCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHH
KENGFPSKIYINDFSKKINKEELEKKKKWNNQWKKLTFALLLLLFSGLGHLAEGRYINFP
HHCCCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEECC
ILGNIFFHASLATLALLFPGREIIINGFKSFIKNRPDMDSLVALGVTSAYITSLLSLIFP
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
ATGFPCFFNEPVMLLGFILIGRFLEERARYQTGSSIGELLDLQPEMANIYTEDNQIKSIR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHCCCCCCEEEEE
VNTLRPNQEIQVLAGDRVPADCIVTQGNSYVDVSHITGESKPIEVKEGENLSSGSLNLNS
EEEECCCCCEEEEECCCCCCCEEEECCCCEEEEEEECCCCCCEEECCCCCCCCCCEECCC
TLRLKVQKVGGDSSLAKLVNLIESVNARKPRIQRIADEIAGKFTYFVLIFATLTFFFWWQ
EEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GARNIWPDLLSHNHQFITHSSHTLHSSLGSNAENFLSLAIQLSIAVLVIACPCALGLATP
CCHHCCHHHHCCCCEEEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TVITVASGKAAKKGVLFKGGDKIEMASKINHIIFDKTGTLTKGKPFIVDYKNNDDYSFLL
CEEEEECCCCCCCCCEEECCCCEEHHHHCCEEEECCCCCCCCCCCEEEEECCCCCHHHHH
KVAASLEKESRHPIADALIQEAKKQNLSLFPIKKIVTHSGRGISGELESIDGLINIGNIE
HHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCCCHHHCCCEEEECCCH
WLLSKGIIIDSDAKKVIENEETKTNTIIGVSIKDKLLGFIFLGDLLRDDSIKTVQNLRKN
HHHHCCEEEECCHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
KFKINILSGDRKQTVLALAKKIGFKEAEVKWDLLPEMKLKTIENLKIDNKVAMIGDGIND
CEEEEEECCCCHHHHHHHHHHCCCCHHCEEEECCCCHHHHHHHCCCCCCEEEEECCCCCC
VPALASSDLGIAVGSGTQIAKANADVVLMGDQLNGLPYALNLAKKTIRKIKQNLTWAFGY
CCHHCCCCCEEEECCCCEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEECCC
NLLAIPIAAGILFPKYGILLTPSIAALLMAISSITVVINALSLD
CHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHEECCCC
>Mature Secondary Structure
MESIQLRITGMKCGGCVSTVEKILNNSDGIENVSVNLLTESAYFEITQKHIEIEAVLKNL
CCCEEEEEEEEECCHHHHHHHHHHCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHH
KENGFPSKIYINDFSKKINKEELEKKKKWNNQWKKLTFALLLLLFSGLGHLAEGRYINFP
HHCCCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEECC
ILGNIFFHASLATLALLFPGREIIINGFKSFIKNRPDMDSLVALGVTSAYITSLLSLIFP
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
ATGFPCFFNEPVMLLGFILIGRFLEERARYQTGSSIGELLDLQPEMANIYTEDNQIKSIR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHCCCCCCEEEEE
VNTLRPNQEIQVLAGDRVPADCIVTQGNSYVDVSHITGESKPIEVKEGENLSSGSLNLNS
EEEECCCCCEEEEECCCCCCCEEEECCCCEEEEEEECCCCCCEEECCCCCCCCCCEECCC
TLRLKVQKVGGDSSLAKLVNLIESVNARKPRIQRIADEIAGKFTYFVLIFATLTFFFWWQ
EEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GARNIWPDLLSHNHQFITHSSHTLHSSLGSNAENFLSLAIQLSIAVLVIACPCALGLATP
CCHHCCHHHHCCCCEEEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TVITVASGKAAKKGVLFKGGDKIEMASKINHIIFDKTGTLTKGKPFIVDYKNNDDYSFLL
CEEEEECCCCCCCCCEEECCCCEEHHHHCCEEEECCCCCCCCCCCEEEEECCCCCHHHHH
KVAASLEKESRHPIADALIQEAKKQNLSLFPIKKIVTHSGRGISGELESIDGLINIGNIE
HHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCCCHHHCCCEEEECCCH
WLLSKGIIIDSDAKKVIENEETKTNTIIGVSIKDKLLGFIFLGDLLRDDSIKTVQNLRKN
HHHHCCEEEECCHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
KFKINILSGDRKQTVLALAKKIGFKEAEVKWDLLPEMKLKTIENLKIDNKVAMIGDGIND
CEEEEEECCCCHHHHHHHHHHCCCCHHCEEEECCCCHHHHHHHCCCCCCEEEEECCCCCC
VPALASSDLGIAVGSGTQIAKANADVVLMGDQLNGLPYALNLAKKTIRKIKQNLTWAFGY
CCHHCCCCCEEEECCCCEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEECCC
NLLAIPIAAGILFPKYGILLTPSIAALLMAISSITVVINALSLD
CHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7937823 [H]