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The map label for this gene is phoP [H]

Identifier: 126698597

GI number: 126698597

Start: 1180992

End: 1181696

Strand: Direct

Name: phoP [H]

Synonym: CD1013

Alternate gene names: 126698597

Gene position: 1180992-1181696 (Clockwise)

Preceding gene: 126698595

Following gene: 126698598

Centisome position: 27.53

GC content: 28.09

Gene sequence:

>705_bases
ATGAGTAAGTTAATTTATATAGCAGATGATGAAGATAATATAAGAAATTTGGTAAAGACATTCTTAAAAAATGAAGGTCA
TGATGTTATGGATTTTAAAACGGGTGATGAACTTTTAGAACAATTTAATATAAAGGAGTGTGACTTAGTAATACTAGATA
TAATGATGCCTGGCTCAAGTGGTTTTGAAGTATGTACAAAACTTCGTGAGAAAAGTACAGTCCCAATAATCATGCTTACT
GCAAGAGATACAGATATAGATTATATTACAGGGATAACCTTAGGTAGTGATGATTATTTTACAAAACCATTTAGCCCAAT
GTCTTTGGTTATGAGAGTAAAATCTATATTTAGAAGGATAGAGTTTGAAAAGAAACAAAATTATGATAAATATAGTAACT
CGATAGATATGGAATTAAAATTTGGTGATGTAATAATAAATAAAAAGAATAAAATCGTTACAAGTAAAAATGTAAATATA
GACCTTACACCAAATGAATATAACCTATTGACTTATTTGTTTGAAAATATAGATAGAGCAGTTTCCAGAGATGAATTATT
AAACAAAATATGGGGATACGATATAGAAGTTGAGACAAGGGCTGCTGATGATACAGTGAAGAGATTACGTAAAAAAATTT
TAAATACAAATATTTTAATAGAAACTGTATGGGGGTTTGGATTTAGGTTGAAGGAGAAAAGTTAA

Upstream 100 bases:

>100_bases
AGTAAAAAATAAGATTTATCTTATCTATTGGGATTTAATTATTTAATCAATATATTTATACCATTTAATTTAAATAAAAA
GTCTATTAAGGAGTGAGCTT

Downstream 100 bases:

>100_bases
GATGAAGAATGGAAATGACAAGAATAGAATTGGAAAGATTAAATCCAAATTTAAATTAAAGTTCTCAAAGAAAAATATAA
GCATAAAAACTAGGATTTTG

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNIKECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLT
ARDTDIDYITGITLGSDDYFTKPFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
DLTPNEYNLLTYLFENIDRAVSRDELLNKIWGYDIEVETRAADDTVKRLRKKILNTNILIETVWGFGFRLKEKS

Sequences:

>Translated_234_residues
MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNIKECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLT
ARDTDIDYITGITLGSDDYFTKPFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
DLTPNEYNLLTYLFENIDRAVSRDELLNKIWGYDIEVETRAADDTVKRLRKKILNTNILIETVWGFGFRLKEKS
>Mature_233_residues
SKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNIKECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTA
RDTDIDYITGITLGSDDYFTKPFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNID
LTPNEYNLLTYLFENIDRAVSRDELLNKIWGYDIEVETRAADDTVKRLRKKILNTNILIETVWGFGFRLKEKS

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=238, Percent_Identity=31.0924369747899, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=31.8777292576419, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=28.5087719298246, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=30.6382978723404, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=32.6086956521739, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=29.4372294372294, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786911, Length=231, Percent_Identity=29.004329004329, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=31.4410480349345, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI2367329, Length=210, Percent_Identity=30.4761904761905, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=30.1310043668122, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786784, Length=187, Percent_Identity=32.620320855615, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI145693140, Length=216, Percent_Identity=30.5555555555556, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI87082012, Length=182, Percent_Identity=30.7692307692308, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787375, Length=231, Percent_Identity=27.7056277056277, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27241; Mature: 27110

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNIKECDLVILDIMMPGSS
CCCEEEEECCCHHHHHHHHHHHCCCCCCEEEECCHHHHHHHCCCCCCCEEEEEEEECCCC
GFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTKPFSPMSLVMRVKSIFRRI
HHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
EFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNIDLTPNEYNLLTYLFENIDRA
HHHHHCCHHHHCCCEEEEEEECEEEEECCCEEEEECCCEEEECCCCHHHHHHHHHHHHHH
VSRDELLNKIWGYDIEVETRAADDTVKRLRKKILNTNILIETVWGFGFRLKEKS
HHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEECCC
>Mature Secondary Structure 
SKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNIKECDLVILDIMMPGSS
CCEEEEECCCHHHHHHHHHHHCCCCCCEEEECCHHHHHHHCCCCCCCEEEEEEEECCCC
GFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTKPFSPMSLVMRVKSIFRRI
HHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
EFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNIDLTPNEYNLLTYLFENIDRA
HHHHHCCHHHHCCCEEEEEEECEEEEECCCEEEEECCCEEEECCCCHHHHHHHHHHHHHH
VSRDELLNKIWGYDIEVETRAADDTVKRLRKKILNTNILIETVWGFGFRLKEKS
HHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]