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The map label for this gene is dasR [H]

Identifier: 126698593

GI number: 126698593

Start: 1177160

End: 1177894

Strand: Direct

Name: dasR [H]

Synonym: CD1009

Alternate gene names: 126698593

Gene position: 1177160-1177894 (Clockwise)

Preceding gene: 126698591

Following gene: 126698594

Centisome position: 27.44

GC content: 30.34

Gene sequence:

>735_bases
ATGAAAATAGTAAATAAATCTAGTAATATACCATTGCATACTCAATTAAGTTCAATAATAAGAGAGATGATAGAAACTGG
TGAGCTTAAAGAGGGCGATGCAATAATGCCAGAAAGAGAACTTTGTAACATACAAAATGTAAGTCGTATGACAGTAAATA
AAACCATTGTTGGATTAGTTACAGAAGGACTTCTTTATAGGGTACAAGGTAAAGGGACATTCGTTGCAAAGCAAAAAAAG
AAGTATCAGTTTTCAAATGTAAAAGGTTTTACTGATGTTATGAAAGAAAAGGGAGTAAACATAAAAACGGATATATTATC
CTTTGAGATGGAACTACCAGATGATTTAGTTAAAAGAAAGCTTGGAATAAGTGATAATACTACAAATATATATAAGATTG
TCAGACTTAGATATACTGATGGAGAGCCATTTGGATTAGAAATAGTATATCTATCAGAAGAAATGTGTAAGGGTCTAACA
AAAGGGATATTGGATAATTCTTCATTATATAGGGTTTTAAATGAAAAATATGGCTATAAGATACAAAAAGCTGAACAGGT
AATGGAGCCAGTAATACTTTCAGATGAAGAAAGTAAGCTTCTTGAAACAGATGAAGGTGCTTTAGCTCTTAAACTTCATA
GAAATTCCTATAATAGAGAAGGTAGCCCTATAGAATATACCATATCAATATTTAGAACAGATAAATATCAATATGAAATA
GTATTGAGTGAGTAG

Upstream 100 bases:

>100_bases
TTTACAAAATAAGTTAAAAAGTATTGAAATAAAATTTCTTTTAAAGTATAATTGGTATATACCAAAATTGGTATATACCA
TATCGAAAAGTGGTGACTAT

Downstream 100 bases:

>100_bases
GTGAATAATATGAAATGTTTAATTAATGGAAAGATAATATTAAAAAATCAAATCTTAGAAAATAAAGTATTAGTATTTGA
TGAAAAAATAATTGATATAG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNIQNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKK
KYQFSNVKGFTDVMKEKGVNIKTDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYNREGSPIEYTISIFRTDKYQYEI
VLSE

Sequences:

>Translated_244_residues
MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNIQNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKK
KYQFSNVKGFTDVMKEKGVNIKTDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYNREGSPIEYTISIFRTDKYQYEI
VLSE
>Mature_244_residues
MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNIQNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKK
KYQFSNVKGFTDVMKEKGVNIKTDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYNREGSPIEYTISIFRTDKYQYEI
VLSE

Specific function: Global regulator that is part of the nutrient-sensing system. In the absence of N-acetylglucosamine 6-P, represses the phosphotransferase system (PTS) specific for the uptake of N- acetylglucosamine (PTSNag), and genes involved in the metabolism of chitin

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=231, Percent_Identity=29.4372294372294, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI87082252, Length=235, Percent_Identity=24.6808510638298, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1790118, Length=208, Percent_Identity=25.9615384615385, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788418, Length=236, Percent_Identity=24.1525423728814, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27925; Mature: 27925

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNIQNVSRMTVNKTIVGLV
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHH
TEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIKTDILSFEMELPDDLVKRK
HCCEEEEEECCCEEEECHHHCCCCCCCCHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHH
LGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLTKGILDNSSLYRVLNEKYGYK
CCCCCCCCEEEEEEEEEECCCCCCEEEEEEECHHHHHHHHHHHCCCHHHHHHHHHHHCCE
IQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYNREGSPIEYTISIFRTDKYQYEI
EHHHHHHHCCEEECCCCHHHEECCCCEEEEEEECCCCCCCCCCEEEEEEEEEECCEEEEE
VLSE
EEEC
>Mature Secondary Structure
MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNIQNVSRMTVNKTIVGLV
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHH
TEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIKTDILSFEMELPDDLVKRK
HCCEEEEEECCCEEEECHHHCCCCCCCCHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHH
LGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLTKGILDNSSLYRVLNEKYGYK
CCCCCCCCEEEEEEEEEECCCCCCEEEEEEECHHHHHHHHHHHCCCHHHHHHHHHHHCCE
IQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYNREGSPIEYTISIFRTDKYQYEI
EHHHHHHHCCEEECCCCHHHEECCCCEEEEEEECCCCCCCCCCEEEEEEEEEECCEEEEE
VLSE
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]