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The map label for this gene is pcaR [H]

Identifier: 126447892

GI number: 126447892

Start: 915805

End: 916755

Strand: Direct

Name: pcaR [H]

Synonym: BMA10247_A0968

Alternate gene names: 126447892

Gene position: 915805-916755 (Clockwise)

Preceding gene: 126446261

Following gene: 126446448

Centisome position: 38.93

GC content: 69.72

Gene sequence:

>951_bases
ATGGCCAAAACCACTACGACCGCCGCGGGTAGACCTGCCGCCGACGCCGCATCGGCCAAGTCGCGCCGTGCCGCGGCCGG
CGCGCGCCCCGAACTTGACGCGGCCGACGACGAAGCCGCGGGCGGCGCATCGTCGTACCTCGTTCCCGGGCTCGAGCGCG
GGCTGCGGATCCTGTCCGAATTTTCCGCGCGCGAGCCGGTGCTGAGCGCGCCGGAGCTGTCCAAGCGCATCGGCATTCCG
CGCACGACGACGTTCCGCCTGCTGCAGACGCTCGAGGCGCTCGGCTTCATCGAGCGCGCGAACGGCGACCGCCATTTCCG
GCTCGGCATCGGCGTGCTGCGGCTCGGTTTCGAATATCTGAATTCGCTCGAATTGACCGATCTCGGCGCGCCGGTGCTCG
AGCGCCTGCGCGACGCGGCCGGGCTGTCGACGCATCTGCTGATCCGCGACCGCCGCGACGTCGTGTTCGTCGCCAAGGCG
CAGAGCAACGCGCCGATGTTCGGCTCGGTGAAGGTGCACGTGGGCACGCGGCTGCCCGCGCACGCGACCGTGCACGGCCA
CGTGTTGATGGGCGACCTCACGCGCGACGCGATGCGCCAGCTCTATCCCGAGAAGCGCCTCGAGGCGTTCACCGAACACA
CGCCCGCGACCGTCGACGAACTGTACGAGCGCGTGCGCCATTACGCGCGTCTCGGTTACGCGCTCAGCGAAGGGGCGTTC
GAGAGCGGGATTTCGGCGGTGACGGCGCCGGTGCGCGACCATTCGGGCTCGATCGTCGCGGCGATCACCGCGACGGTGCC
GCGCTCGGAAATTGGCGCCGTCGACGAAAAGGAGCGGCTCGTCGAACTCGTGTGCGGCGCGGCCGTCGATTTGTCGCAGC
GGCTGAACTACCGGCCGCTCGACGGCGATCCGACCGTCGCGCATGCGCGGCACAAGGTTGCGTTGTTCTGA

Upstream 100 bases:

>100_bases
GTTCGCGCGGATGACGCGGGCCCGCCCGCGCGCCGAAACCGCGCGGCCTTCGGATGATGTCGCGTTATGATTCGGTTTCT
CTCCGTCCCTTGCAGCCGAC

Downstream 100 bases:

>100_bases
CGACGTCCGGCCGCATCGAGCGGGGCGCACATGCGGCGTATTGCGGCGCGCGCCGCGGCGGCCGATGATGCCGGCGCCGG
GGGCGGCATGGCGTAGGCAG

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MAKTTTTAAGRPAADAASAKSRRAAAGARPELDAADDEAAGGASSYLVPGLERGLRILSEFSAREPVLSAPELSKRIGIP
RTTTFRLLQTLEALGFIERANGDRHFRLGIGVLRLGFEYLNSLELTDLGAPVLERLRDAAGLSTHLLIRDRRDVVFVAKA
QSNAPMFGSVKVHVGTRLPAHATVHGHVLMGDLTRDAMRQLYPEKRLEAFTEHTPATVDELYERVRHYARLGYALSEGAF
ESGISAVTAPVRDHSGSIVAAITATVPRSEIGAVDEKERLVELVCGAAVDLSQRLNYRPLDGDPTVAHARHKVALF

Sequences:

>Translated_316_residues
MAKTTTTAAGRPAADAASAKSRRAAAGARPELDAADDEAAGGASSYLVPGLERGLRILSEFSAREPVLSAPELSKRIGIP
RTTTFRLLQTLEALGFIERANGDRHFRLGIGVLRLGFEYLNSLELTDLGAPVLERLRDAAGLSTHLLIRDRRDVVFVAKA
QSNAPMFGSVKVHVGTRLPAHATVHGHVLMGDLTRDAMRQLYPEKRLEAFTEHTPATVDELYERVRHYARLGYALSEGAF
ESGISAVTAPVRDHSGSIVAAITATVPRSEIGAVDEKERLVELVCGAAVDLSQRLNYRPLDGDPTVAHARHKVALF
>Mature_315_residues
AKTTTTAAGRPAADAASAKSRRAAAGARPELDAADDEAAGGASSYLVPGLERGLRILSEFSAREPVLSAPELSKRIGIPR
TTTFRLLQTLEALGFIERANGDRHFRLGIGVLRLGFEYLNSLELTDLGAPVLERLRDAAGLSTHLLIRDRRDVVFVAKAQ
SNAPMFGSVKVHVGTRLPAHATVHGHVLMGDLTRDAMRQLYPEKRLEAFTEHTPATVDELYERVRHYARLGYALSEGAFE
SGISAVTAPVRDHSGSIVAAITATVPRSEIGAVDEKERLVELVCGAAVDLSQRLNYRPLDGDPTVAHARHKVALF

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786715, Length=251, Percent_Identity=26.2948207171315, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786468, Length=253, Percent_Identity=28.4584980237154, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082359, Length=224, Percent_Identity=25.4464285714286, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1789999, Length=263, Percent_Identity=23.1939163498099, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788581, Length=258, Percent_Identity=27.1317829457364, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788131, Length=231, Percent_Identity=25.1082251082251, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 34085; Mature: 33954

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTTTTAAGRPAADAASAKSRRAAAGARPELDAADDEAAGGASSYLVPGLERGLRILSE
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
FSAREPVLSAPELSKRIGIPRTTTFRLLQTLEALGFIERANGDRHFRLGIGVLRLGFEYL
HHHCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHH
NSLELTDLGAPVLERLRDAAGLSTHLLIRDRRDVVFVAKAQSNAPMFGSVKVHVGTRLPA
CCCCHHHCCHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEEEECCCCCC
HATVHGHVLMGDLTRDAMRQLYPEKRLEAFTEHTPATVDELYERVRHYARLGYALSEGAF
CCEEECEEEECHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHH
ESGISAVTAPVRDHSGSIVAAITATVPRSEIGAVDEKERLVELVCGAAVDLSQRLNYRPL
HHCHHHHCCCCCCCCCCEEEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
DGDPTVAHARHKVALF
CCCCCHHHCCCEEECC
>Mature Secondary Structure 
AKTTTTAAGRPAADAASAKSRRAAAGARPELDAADDEAAGGASSYLVPGLERGLRILSE
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
FSAREPVLSAPELSKRIGIPRTTTFRLLQTLEALGFIERANGDRHFRLGIGVLRLGFEYL
HHHCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHH
NSLELTDLGAPVLERLRDAAGLSTHLLIRDRRDVVFVAKAQSNAPMFGSVKVHVGTRLPA
CCCCHHHCCHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEEEECCCCCC
HATVHGHVLMGDLTRDAMRQLYPEKRLEAFTEHTPATVDELYERVRHYARLGYALSEGAF
CCEEECEEEECHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHH
ESGISAVTAPVRDHSGSIVAAITATVPRSEIGAVDEKERLVELVCGAAVDLSQRLNYRPL
HHCHHHHCCCCCCCCCCEEEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
DGDPTVAHARHKVALF
CCCCCHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]