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The map label for this gene is mntH [H]

Identifier: 126447874

GI number: 126447874

Start: 1007909

End: 1009222

Strand: Direct

Name: mntH [H]

Synonym: BMA10247_A1068

Alternate gene names: 126447874

Gene position: 1007909-1009222 (Clockwise)

Preceding gene: 126447344

Following gene: 126447038

Centisome position: 42.84

GC content: 71.54

Gene sequence:

>1314_bases
ATGCTTTCCTCAACCACGATGAGCCGATCCGCCGGCGATTTCGCGACGGCGGGAGACGCGAGCTCGCGCACCGTCCGCGC
CGCGCGCGACGCGCTCGAAGGGCGCCGCAAGGGCGTCGCGGCCGCGCTGCCGTTCGTCGGGCCGGCCGTGATCGCGTCGA
TCGGCTACATGGACCCCGGCAACTTCGCGACCAACATCCAGGCGGGCGCCGCGTACGGCTACGAGCTGCTGTGGGTCGTG
CTCGCCGCGAACGTGATCGCGATGGTGTTTCAGGCGATGTCGGCGAAGCTCGGCATCGTGACGGGCCGCAACCTCGCCGA
GCTGTGCCGCGAGCATTTTCCGCGGCCCGTCGTCTGGGGGATGTGGGCGACGTCCGAGATCGCCGCGATGGCGACCGATC
TCGCCGAATTCCTGGGCGGGGCGCTCGCGTTCGGCCTGCTGCTGCATCTGCCGCTCATCGCCGGGATGGCCGCGACGGCG
GTGCTGACCTGCGCGATCCTCACGCTGGAAAAGCGCGGCTTCCGGCCGCTCGAGGCCGCGATCGCGGCGCTGGTCGGCGT
GATCGGCGCGAGCTACCTCGGCGAATTGCTGATCGCGCCGCAGGACTGGCACGCGGCCGCATACCATCTCGTCGTGCCGC
AGTTGCGCGACGGCACGGCGCTCACGCTCGCGGTGGGCATCATCGGCGCGACGATCATGCCGCACACGCTCTATCTGCAC
TCCGGCCTCACGCAGCGGCGCACGACGCCGCGCGACGCGCGCGAGCGCCGGCTGCTGCTGCGCTTCTCGAACCGCGAGGT
CGCGGTCGCGCTCGGCGTCGCCGGCTTCGTGAACATCGCGATGGTGATGATGGCGTCGTCCGCGTTCCACCGGACGGCGC
CGGGCATGGCCGATATCGGCGACGCGTATCACACGCTGATTCCGCTGCTCGGCCCGGCGGCGGGCGCGCTCTTTCTCGTC
GCGCTGTTCGCGTCCGGCGTGTCGAGTTCGGTCGTCGGCACGCTCGCGGGGCAGGTCGTGATGCAGGGCTTCCTGCGTCG
CCGGGTGCCGATCTGGGTGCGGCGGCTCGTGACGATCGCGCCCGCGTTCGCGATCGTCGCGCTCGGCTGCGACGTCACGC
GCGCGATGGTGCTGAGCCAGGTCGTGCTGAGCCTCGTGCTGCCGCTGCCGATGGCCGCGCTGCTGCTGCTGTCGAGCCGG
CGCGCGCTGCTCGGCGAGCATGCGCTGCGCGCGCCGACGCTCGTCGCGGCGAGCGCGGCGGCGGCGGCGATCGTCGCGTT
GAACGTGTATCTGATCTGGGCGGCGTTCAATTGA

Upstream 100 bases:

>100_bases
AAGCGCGCGGCGCGCGGGCGGCCTAACCGGCCGCCGCCCGGTCGCGCGGCCTGCCGCGCCGCGCATGTCCAATCATGCTG
CACTCCAACGGATACCCACC

Downstream 100 bases:

>100_bases
ACGAGCGCGCAGGCGGGGCGGCGCGCGTGTTTCGCGCCGGCGGAGCGGGGCAGTCAATGCGCGGCATGGCGGCCGCCTCG
CTCGACCGAATCGCGAACGC

Product: manganese/iron transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MLSSTTMSRSAGDFATAGDASSRTVRAARDALEGRRKGVAAALPFVGPAVIASIGYMDPGNFATNIQAGAAYGYELLWVV
LAANVIAMVFQAMSAKLGIVTGRNLAELCREHFPRPVVWGMWATSEIAAMATDLAEFLGGALAFGLLLHLPLIAGMAATA
VLTCAILTLEKRGFRPLEAAIAALVGVIGASYLGELLIAPQDWHAAAYHLVVPQLRDGTALTLAVGIIGATIMPHTLYLH
SGLTQRRTTPRDARERRLLLRFSNREVAVALGVAGFVNIAMVMMASSAFHRTAPGMADIGDAYHTLIPLLGPAAGALFLV
ALFASGVSSSVVGTLAGQVVMQGFLRRRVPIWVRRLVTIAPAFAIVALGCDVTRAMVLSQVVLSLVLPLPMAALLLLSSR
RALLGEHALRAPTLVAASAAAAAIVALNVYLIWAAFN

Sequences:

>Translated_437_residues
MLSSTTMSRSAGDFATAGDASSRTVRAARDALEGRRKGVAAALPFVGPAVIASIGYMDPGNFATNIQAGAAYGYELLWVV
LAANVIAMVFQAMSAKLGIVTGRNLAELCREHFPRPVVWGMWATSEIAAMATDLAEFLGGALAFGLLLHLPLIAGMAATA
VLTCAILTLEKRGFRPLEAAIAALVGVIGASYLGELLIAPQDWHAAAYHLVVPQLRDGTALTLAVGIIGATIMPHTLYLH
SGLTQRRTTPRDARERRLLLRFSNREVAVALGVAGFVNIAMVMMASSAFHRTAPGMADIGDAYHTLIPLLGPAAGALFLV
ALFASGVSSSVVGTLAGQVVMQGFLRRRVPIWVRRLVTIAPAFAIVALGCDVTRAMVLSQVVLSLVLPLPMAALLLLSSR
RALLGEHALRAPTLVAASAAAAAIVALNVYLIWAAFN
>Mature_437_residues
MLSSTTMSRSAGDFATAGDASSRTVRAARDALEGRRKGVAAALPFVGPAVIASIGYMDPGNFATNIQAGAAYGYELLWVV
LAANVIAMVFQAMSAKLGIVTGRNLAELCREHFPRPVVWGMWATSEIAAMATDLAEFLGGALAFGLLLHLPLIAGMAATA
VLTCAILTLEKRGFRPLEAAIAALVGVIGASYLGELLIAPQDWHAAAYHLVVPQLRDGTALTLAVGIIGATIMPHTLYLH
SGLTQRRTTPRDARERRLLLRFSNREVAVALGVAGFVNIAMVMMASSAFHRTAPGMADIGDAYHTLIPLLGPAAGALFLV
ALFASGVSSSVVGTLAGQVVMQGFLRRRVPIWVRRLVTIAPAFAIVALGCDVTRAMVLSQVVLSLVLPLPMAALLLLSSR
RALLGEHALRAPTLVAASAAAAAIVALNVYLIWAAFN

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=427, Percent_Identity=32.7868852459016, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI295293178, Length=476, Percent_Identity=28.9915966386555, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI295293167, Length=476, Percent_Identity=28.9915966386555, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI295293171, Length=476, Percent_Identity=28.9915966386555, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI295293169, Length=476, Percent_Identity=28.9915966386555, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI295293175, Length=476, Percent_Identity=28.9915966386555, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI295293173, Length=476, Percent_Identity=28.9915966386555, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI10835169, Length=476, Percent_Identity=28.9915966386555, Blast_Score=157, Evalue=2e-38,
Organism=Escherichia coli, GI1788736, Length=391, Percent_Identity=48.3375959079284, Blast_Score=350, Evalue=1e-97,
Organism=Caenorhabditis elegans, GI17569473, Length=396, Percent_Identity=30.5555555555556, Blast_Score=181, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI71999499, Length=432, Percent_Identity=30.3240740740741, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI193210616, Length=428, Percent_Identity=30.3738317757009, Blast_Score=171, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI71993856, Length=246, Percent_Identity=33.739837398374, Blast_Score=134, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6324450, Length=441, Percent_Identity=31.9727891156463, Blast_Score=206, Evalue=7e-54,
Organism=Saccharomyces cerevisiae, GI6323062, Length=408, Percent_Identity=32.843137254902, Blast_Score=206, Evalue=7e-54,
Organism=Saccharomyces cerevisiae, GI6321841, Length=441, Percent_Identity=31.2925170068027, Blast_Score=189, Evalue=6e-49,
Organism=Drosophila melanogaster, GI24648607, Length=428, Percent_Identity=31.3084112149533, Blast_Score=192, Evalue=4e-49,
Organism=Drosophila melanogaster, GI281362176, Length=428, Percent_Identity=31.3084112149533, Blast_Score=192, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24648609, Length=428, Percent_Identity=31.3084112149533, Blast_Score=192, Evalue=4e-49,
Organism=Drosophila melanogaster, GI45553443, Length=402, Percent_Identity=32.8358208955224, Blast_Score=190, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 45777; Mature: 45777

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSSTTMSRSAGDFATAGDASSRTVRAARDALEGRRKGVAAALPFVGPAVIASIGYMDPG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHCCCCCC
NFATNIQAGAAYGYELLWVVLAANVIAMVFQAMSAKLGIVTGRNLAELCREHFPRPVVWG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCHHHHHHHHCCCCEEEC
MWATSEIAAMATDLAEFLGGALAFGLLLHLPLIAGMAATAVLTCAILTLEKRGFRPLEAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
IAALVGVIGASYLGELLIAPQDWHAAAYHLVVPQLRDGTALTLAVGIIGATIMPHTLYLH
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SGLTQRRTTPRDARERRLLLRFSNREVAVALGVAGFVNIAMVMMASSAFHRTAPGMADIG
CCCHHCCCCCCHHHHHEEHHEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
DAYHTLIPLLGPAAGALFLVALFASGVSSSVVGTLAGQVVMQGFLRRRVPIWVRRLVTIA
HHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
PAFAIVALGCDVTRAMVLSQVVLSLVLPLPMAALLLLSSRRALLGEHALRAPTLVAASAA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AAAIVALNVYLIWAAFN
HHHHHHHHHHHEEEECC
>Mature Secondary Structure
MLSSTTMSRSAGDFATAGDASSRTVRAARDALEGRRKGVAAALPFVGPAVIASIGYMDPG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHCCCCCC
NFATNIQAGAAYGYELLWVVLAANVIAMVFQAMSAKLGIVTGRNLAELCREHFPRPVVWG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCHHHHHHHHCCCCEEEC
MWATSEIAAMATDLAEFLGGALAFGLLLHLPLIAGMAATAVLTCAILTLEKRGFRPLEAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
IAALVGVIGASYLGELLIAPQDWHAAAYHLVVPQLRDGTALTLAVGIIGATIMPHTLYLH
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SGLTQRRTTPRDARERRLLLRFSNREVAVALGVAGFVNIAMVMMASSAFHRTAPGMADIG
CCCHHCCCCCCHHHHHEEHHEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
DAYHTLIPLLGPAAGALFLVALFASGVSSSVVGTLAGQVVMQGFLRRRVPIWVRRLVTIA
HHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
PAFAIVALGCDVTRAMVLSQVVLSLVLPLPMAALLLLSSRRALLGEHALRAPTLVAASAA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AAAIVALNVYLIWAAFN
HHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA