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The map label for this gene is czcB [H]

Identifier: 126447709

GI number: 126447709

Start: 1153160

End: 1154629

Strand: Reverse

Name: czcB [H]

Synonym: BMA10247_A1182

Alternate gene names: 126447709

Gene position: 1154629-1153160 (Counterclockwise)

Preceding gene: 126447292

Following gene: 126445970

Centisome position: 49.08

GC content: 72.65

Gene sequence:

>1470_bases
ATGCAACGCAAGCCCCTGATTCTCGCCGGCGCGGCCGCGGCCGGCGCTCTCGCCATCGTGCTGGCGCTCGCGCGCGCGCC
GTCCACGTCGTCCGCGCCGGCGGCCTCCGGGGCCGCCGCGGCCGCGCCCGCATCCGGCGCGACCGGCCCGCACGGCGGTG
CGATGTTCGCGCAAGGCGCGCTGTCCGCCGAAATCGTGCTGTCCGAGAAGCCGGACGACGCGCGCCTCGTCGTCTATCCG
TTCGTCGACGGCAAGCCCGTCGAGCAAGGCGCGGCCGTCTCCGCGACGCTGACCCGCCACGACGGCGAACGCGTCGCGCT
GCAGTTCGCGCAAGCGGGCGCGAAGTACACGTCGGCGCAGCCGATCGCGAGGCCGCACGTGTTCGACGCGTCGATCGACG
TGAGGATCGGCGCGCGCAGCGCATCGTTTCCGTTCTCGCGCGCGGACGGCGCGATCGCGCTGGACGACGCTCAGCTCGGC
GCGGCGAGGATCGGCATCGCGCGCGCGGGCCCCGCGCAGATCATCACGAGCTTCCAGTTGCCGGGCGAAATCAAGTTCAA
CGAGGATCGCACCGCGCACGTCGTGCCGCGCGTCGCGGGGATCGTCGAGCGGGTCGCCGTGTCGATCGGCGAGAACGTCA
AGCCAGGGCAAGTGCTCGCGGTGATCGCGAGCACGGATCTCGCCGATCGCCGCAGCGAGCTGATGACGGCCGAGCGCCGG
CTGCAGGCGGCCCGCACGTCGTACGCGCGCGAGAAGACCTTGTGGGAGGAGCGGATCTCCGCGGAGCAGGACTATCTGCA
GGCGCAGGTGCAACTGCGCGAGGCGGAGATCGCCGCGGCGAACGCGCGGCAGAAACTCGCCGCGCTGAACGCGAGCGCCG
CATCCGGCGCGCTCAACCGCTACGAGCTGCGCGCGCCGTTCGCGGGCACCATCGTCGAGAAGCACATCGCGCCGGGCGAG
GCGATCGCGGCCGACGCGAACGTGTTCGTCGTGTCCGATCTGTCGTCGGTGTGGGCCGAAATGGCCGTGCCCGCGCAGCG
CCTGAACGACGTGCGCGTCGGCCGCCACGCGACGGTCAGCGCGGCCGCGTTCGAATCGAAGTCGAGCGGGCCGATCGCGT
ACGTCGGCGCGCTGCTCGGCGAGCAGACCCGCACCGCGCCCGCGCGCGTCGTGCTGCCGAATCCCGACGGCGCGTGGCGG
CCGGGCATGTTCGTCAACGTGACCGTCGACGCCGGCGCGCAAAACGTGCCCGTCGCTGTCGAGAGCGACGCGCTGCAGGA
CGTCGACGGCGCGCCCGCCGTGTTCGTTCGAACGCCGAAGGGTTTCGTCGCGCAGGCGATCGAGACGGGCCGGCGCGACG
AGCGGCGCGTCGAGATCGTCAAGGGCCTCGCGCCCGGTCAGACCTACGCCGCGGCGAACAGCTTCGTGCTGAAGGCGGAG
CTCGGCAAGGGCGTCGCCGACGAGCACTGA

Upstream 100 bases:

>100_bases
GCCGACGCGCATCAGTCGTATGCGGACATCGAGCGCGTCGTCGGCGCGCCGGCGCGCGACGCTTCCCGCCCCCTCGCCCA
ACTTCGCTGAAGAACTCGCC

Downstream 100 bases:

>100_bases
CGCGCGGGCCGCTTCGTTTTCCACGCATTCCAGAGGACCGTCACCATGTTTGAGCGCCTGATCCGCTTCGCGATCGCGCA
CCGCTGGCTCGTGATGCTCG

Product: heavy metal resistance protein CzcB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MQRKPLILAGAAAAGALAIVLALARAPSTSSAPAASGAAAAAPASGATGPHGGAMFAQGALSAEIVLSEKPDDARLVVYP
FVDGKPVEQGAAVSATLTRHDGERVALQFAQAGAKYTSAQPIARPHVFDASIDVRIGARSASFPFSRADGAIALDDAQLG
AARIGIARAGPAQIITSFQLPGEIKFNEDRTAHVVPRVAGIVERVAVSIGENVKPGQVLAVIASTDLADRRSELMTAERR
LQAARTSYAREKTLWEERISAEQDYLQAQVQLREAEIAAANARQKLAALNASAASGALNRYELRAPFAGTIVEKHIAPGE
AIAADANVFVVSDLSSVWAEMAVPAQRLNDVRVGRHATVSAAAFESKSSGPIAYVGALLGEQTRTAPARVVLPNPDGAWR
PGMFVNVTVDAGAQNVPVAVESDALQDVDGAPAVFVRTPKGFVAQAIETGRRDERRVEIVKGLAPGQTYAAANSFVLKAE
LGKGVADEH

Sequences:

>Translated_489_residues
MQRKPLILAGAAAAGALAIVLALARAPSTSSAPAASGAAAAAPASGATGPHGGAMFAQGALSAEIVLSEKPDDARLVVYP
FVDGKPVEQGAAVSATLTRHDGERVALQFAQAGAKYTSAQPIARPHVFDASIDVRIGARSASFPFSRADGAIALDDAQLG
AARIGIARAGPAQIITSFQLPGEIKFNEDRTAHVVPRVAGIVERVAVSIGENVKPGQVLAVIASTDLADRRSELMTAERR
LQAARTSYAREKTLWEERISAEQDYLQAQVQLREAEIAAANARQKLAALNASAASGALNRYELRAPFAGTIVEKHIAPGE
AIAADANVFVVSDLSSVWAEMAVPAQRLNDVRVGRHATVSAAAFESKSSGPIAYVGALLGEQTRTAPARVVLPNPDGAWR
PGMFVNVTVDAGAQNVPVAVESDALQDVDGAPAVFVRTPKGFVAQAIETGRRDERRVEIVKGLAPGQTYAAANSFVLKAE
LGKGVADEH
>Mature_489_residues
MQRKPLILAGAAAAGALAIVLALARAPSTSSAPAASGAAAAAPASGATGPHGGAMFAQGALSAEIVLSEKPDDARLVVYP
FVDGKPVEQGAAVSATLTRHDGERVALQFAQAGAKYTSAQPIARPHVFDASIDVRIGARSASFPFSRADGAIALDDAQLG
AARIGIARAGPAQIITSFQLPGEIKFNEDRTAHVVPRVAGIVERVAVSIGENVKPGQVLAVIASTDLADRRSELMTAERR
LQAARTSYAREKTLWEERISAEQDYLQAQVQLREAEIAAANARQKLAALNASAASGALNRYELRAPFAGTIVEKHIAPGE
AIAADANVFVVSDLSSVWAEMAVPAQRLNDVRVGRHATVSAAAFESKSSGPIAYVGALLGEQTRTAPARVVLPNPDGAWR
PGMFVNVTVDAGAQNVPVAVESDALQDVDGAPAVFVRTPKGFVAQAIETGRRDERRVEIVKGLAPGQTYAAANSFVLKAE
LGKGVADEH

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Attached To The Inner Membrane By A Lipid Anchor [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=278, Percent_Identity=24.8201438848921, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI87081796, Length=305, Percent_Identity=24.9180327868852, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 50767; Mature: 50767

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRKPLILAGAAAAGALAIVLALARAPSTSSAPAASGAAAAAPASGATGPHGGAMFAQGA
CCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCC
LSAEIVLSEKPDDARLVVYPFVDGKPVEQGAAVSATLTRHDGERVALQFAQAGAKYTSAQ
CEEEEEEECCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCC
PIARPHVFDASIDVRIGARSASFPFSRADGAIALDDAQLGAARIGIARAGPAQIITSFQL
CCCCCEEECCEEEEEECCCCCCCCCCCCCCCEEECCCCCCHHHEEECCCCHHHHHEEECC
PGEIKFNEDRTAHVVPRVAGIVERVAVSIGENVKPGQVLAVIASTDLADRRSELMTAERR
CCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHH
LQAARTSYAREKTLWEERISAEQDYLQAQVQLREAEIAAANARQKLAALNASAASGALNR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCE
YELRAPFAGTIVEKHIAPGEAIAADANVFVVSDLSSVWAEMAVPAQRLNDVRVGRHATVS
EEECCCCHHHHHHHHCCCCCCEECCCCEEEEECHHHHHHHHCCCHHHHHHCCCCCCCEEE
AAAFESKSSGPIAYVGALLGEQTRTAPARVVLPNPDGAWRPGMFVNVTVDAGAQNVPVAV
HHHHCCCCCCCCEEHHHHHCCCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCCCCEEE
ESDALQDVDGAPAVFVRTPKGFVAQAIETGRRDERRVEIVKGLAPGQTYAAANSFVLKAE
CCCCHHCCCCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEE
LGKGVADEH
CCCCCCCCC
>Mature Secondary Structure
MQRKPLILAGAAAAGALAIVLALARAPSTSSAPAASGAAAAAPASGATGPHGGAMFAQGA
CCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCC
LSAEIVLSEKPDDARLVVYPFVDGKPVEQGAAVSATLTRHDGERVALQFAQAGAKYTSAQ
CEEEEEEECCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCC
PIARPHVFDASIDVRIGARSASFPFSRADGAIALDDAQLGAARIGIARAGPAQIITSFQL
CCCCCEEECCEEEEEECCCCCCCCCCCCCCCEEECCCCCCHHHEEECCCCHHHHHEEECC
PGEIKFNEDRTAHVVPRVAGIVERVAVSIGENVKPGQVLAVIASTDLADRRSELMTAERR
CCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHH
LQAARTSYAREKTLWEERISAEQDYLQAQVQLREAEIAAANARQKLAALNASAASGALNR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCE
YELRAPFAGTIVEKHIAPGEAIAADANVFVVSDLSSVWAEMAVPAQRLNDVRVGRHATVS
EEECCCCHHHHHHHHCCCCCCEECCCCEEEEECHHHHHHHHCCCHHHHHHCCCCCCCEEE
AAAFESKSSGPIAYVGALLGEQTRTAPARVVLPNPDGAWRPGMFVNVTVDAGAQNVPVAV
HHHHCCCCCCCCEEHHHHHCCCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCCCCEEE
ESDALQDVDGAPAVFVRTPKGFVAQAIETGRRDERRVEIVKGLAPGQTYAAANSFVLKAE
CCCCHHCCCCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEE
LGKGVADEH
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]