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The map label for this gene is 126447618

Identifier: 126447618

GI number: 126447618

Start: 1970192

End: 1971214

Strand: Reverse

Name: 126447618

Synonym: BMA10247_A2035

Alternate gene names: NA

Gene position: 1971214-1970192 (Counterclockwise)

Preceding gene: 262192892

Following gene: 126446263

Centisome position: 83.79

GC content: 72.63

Gene sequence:

>1023_bases
ATGGGGATGACGACGCGGCCGCAGGCGAACGCGAAGGCGCGCGCGCGCAAGGCGGCCGCGCGCGGGGAGCCGGCGCGCGG
CGCGCTGCTGCGCGTCACGCATGATACGCGCTATCGATACGCGGCGCGCGTCGAATCCGCGCAGCATCAGGCGCGTCTGC
GCCCGCTCGAGACGCCGCGGCAGCGCGTGATCGAGTTCTCGCTCGAGATCGAGCCGCGCGCGGAAGGGCTCGTCGTCGAC
ATCGATTCGTTCGGCAACGAGCGCGCTTCGTTCGCGCTCAACCAGCCGCACGAGGAGCTGTTCGTGCGCAGCCGCAGCGT
CGTGCGCGTCACGCCGCCCGCGCTGGCGGCGGGCAAGCGCGGCGAGCCGCCGCCCGCCGTCGCCGCGCCGCGCGACGGCT
GCGCGAGCGCGTGGGAAGCGGTGCGTGAGCGCCTGACGTTTCGTGCCGGCCGCCCGTTCGATCCGGCGAGCGAATTCGTG
TTCGCTTCGCCGCACGTCGCATGCCACTCCGATCTCGCCGCCTATGCGGCGGCGAGCTTCACGCCGGGCCGGCCGCTCGT
GCAGGCCGCGTGGGAGCTGATGCGCCGCATCCACGCGGATTTCGCGTATGCGCCGAACAGCACCGACGTCGGCACGACCG
TGCTCGATGCGCTCGCGCTGCGCCAGGGCGTGTGCCAGGATTTCGCGCACGTGATGATCGGCGCGCTGCGCTCGCTCGGG
CTTGCCGCGCGCTACGTGAGCGGCTATCTGCTGACGCAGCCGCCGCCCGGGCAGCCGCGATTGATCGGCGCGGACGCATC
GCATGCGTGGGTCGAGGTCTACGATCCCGCGTGGCCCGAGGACGGTGGCTGGCTGCCGCTCGATCCGACCAACGATCGCG
CGCCCGGCGACGATTACGTGATGTTGTCGATCGGCCGCGACTACGCGGACGTGACGCCGTTGCGCGGCGTCATTCGCGGC
GGCGGGGCCGATCAGGTGCTGACGGTCGGCGTGACGGTGGAGCCGCTCGATTCGGCGTCCTGA

Upstream 100 bases:

>100_bases
TGCTCGCGCGCCTGCAAGCGTGCGGCAAGGCGGCGTGGGACGTGTCGAACCGGATCGGCGAGCGCTATTTCAGCCACGTG
CGCGATGCGGGCAGGTCGCT

Downstream 100 bases:

>100_bases
CTGTTCGAGGACGGCGCGCGGCCGTTGCGCATGTCGCGCCGGATATTGCGCGTGGGGGCGAGACGAGATGTCGCTCGATG
CGAGCGATGAGTGATCGTTG

Product: transglutaminase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MGMTTRPQANAKARARKAAARGEPARGALLRVTHDTRYRYAARVESAQHQARLRPLETPRQRVIEFSLEIEPRAEGLVVD
IDSFGNERASFALNQPHEELFVRSRSVVRVTPPALAAGKRGEPPPAVAAPRDGCASAWEAVRERLTFRAGRPFDPASEFV
FASPHVACHSDLAAYAAASFTPGRPLVQAAWELMRRIHADFAYAPNSTDVGTTVLDALALRQGVCQDFAHVMIGALRSLG
LAARYVSGYLLTQPPPGQPRLIGADASHAWVEVYDPAWPEDGGWLPLDPTNDRAPGDDYVMLSIGRDYADVTPLRGVIRG
GGADQVLTVGVTVEPLDSAS

Sequences:

>Translated_340_residues
MGMTTRPQANAKARARKAAARGEPARGALLRVTHDTRYRYAARVESAQHQARLRPLETPRQRVIEFSLEIEPRAEGLVVD
IDSFGNERASFALNQPHEELFVRSRSVVRVTPPALAAGKRGEPPPAVAAPRDGCASAWEAVRERLTFRAGRPFDPASEFV
FASPHVACHSDLAAYAAASFTPGRPLVQAAWELMRRIHADFAYAPNSTDVGTTVLDALALRQGVCQDFAHVMIGALRSLG
LAARYVSGYLLTQPPPGQPRLIGADASHAWVEVYDPAWPEDGGWLPLDPTNDRAPGDDYVMLSIGRDYADVTPLRGVIRG
GGADQVLTVGVTVEPLDSAS
>Mature_339_residues
GMTTRPQANAKARARKAAARGEPARGALLRVTHDTRYRYAARVESAQHQARLRPLETPRQRVIEFSLEIEPRAEGLVVDI
DSFGNERASFALNQPHEELFVRSRSVVRVTPPALAAGKRGEPPPAVAAPRDGCASAWEAVRERLTFRAGRPFDPASEFVF
ASPHVACHSDLAAYAAASFTPGRPLVQAAWELMRRIHADFAYAPNSTDVGTTVLDALALRQGVCQDFAHVMIGALRSLGL
AARYVSGYLLTQPPPGQPRLIGADASHAWVEVYDPAWPEDGGWLPLDPTNDRAPGDDYVMLSIGRDYADVTPLRGVIRGG
GADQVLTVGVTVEPLDSAS

Specific function: Unknown

COG id: COG1305

COG function: function code E; Transglutaminase-like enzymes, putative cysteine proteases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML0607 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013589
- InterPro:   IPR002931 [H]

Pfam domain/function: PF08379 Bact_transglu_N; PF01841 Transglut_core [H]

EC number: NA

Molecular weight: Translated: 36773; Mature: 36642

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMTTRPQANAKARARKAAARGEPARGALLRVTHDTRYRYAARVESAQHQARLRPLETPR
CCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHH
QRVIEFSLEIEPRAEGLVVDIDSFGNERASFALNQPHEELFVRSRSVVRVTPPALAAGKR
HHHEEEEEEECCCCCEEEEECCCCCCCCCEEECCCCHHHHHHHCCCEEEECCCHHHCCCC
GEPPPAVAAPRDGCASAWEAVRERLTFRAGRPFDPASEFVFASPHVACHSDLAAYAAASF
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHCEEECCCCHHHHHHHHHHHHHCC
TPGRPLVQAAWELMRRIHADFAYAPNSTDVGTTVLDALALRQGVCQDFAHVMIGALRSLG
CCCCHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAARYVSGYLLTQPPPGQPRLIGADASHAWVEVYDPAWPEDGGWLPLDPTNDRAPGDDYV
HHHHHHCCEEEECCCCCCCEEEECCCCCCEEEEECCCCCCCCCEECCCCCCCCCCCCCEE
MLSIGRDYADVTPLRGVIRGGGADQVLTVGVTVEPLDSAS
EEEECCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCC
>Mature Secondary Structure 
GMTTRPQANAKARARKAAARGEPARGALLRVTHDTRYRYAARVESAQHQARLRPLETPR
CCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHH
QRVIEFSLEIEPRAEGLVVDIDSFGNERASFALNQPHEELFVRSRSVVRVTPPALAAGKR
HHHEEEEEEECCCCCEEEEECCCCCCCCCEEECCCCHHHHHHHCCCEEEECCCHHHCCCC
GEPPPAVAAPRDGCASAWEAVRERLTFRAGRPFDPASEFVFASPHVACHSDLAAYAAASF
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHCEEECCCCHHHHHHHHHHHHHCC
TPGRPLVQAAWELMRRIHADFAYAPNSTDVGTTVLDALALRQGVCQDFAHVMIGALRSLG
CCCCHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAARYVSGYLLTQPPPGQPRLIGADASHAWVEVYDPAWPEDGGWLPLDPTNDRAPGDDYV
HHHHHHCCEEEECCCCCCCEEEECCCCCCEEEEECCCCCCCCCEECCCCCCCCCCCCCEE
MLSIGRDYADVTPLRGVIRGGGADQVLTVGVTVEPLDSAS
EEEECCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]