BacMap

Definition	Burkholderia mallei NCTC 10247 chromosome II, complete genome.
Accession	NC_009079
Length	2,352,693

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The map label for this gene is ucpA [C]

Identifier: 126447602

GI number: 126447602

Start: 923421

End: 924218

Strand: Direct

Name: ucpA [C]

Synonym: BMA10247_A0977

Alternate gene names: 126447602

Gene position: 923421-924218 (Clockwise)

Preceding gene: 126447850

Following gene: 126446508

Centisome position: 39.25

GC content: 68.8

Gene sequence:

>798_bases
ATGATCCAGATCGACTTGAGCGGGCAGGTCGCCGTGGTGACGGGCGGCTCGTCCGGCATCGGCTACGCGAGCGCCGAGCT
CTTCCTGCGCGCGGGCGCGTCGGTCGCGATATGCGGCCGCGGCGATGAGCGGCTCGCGAGCGCGCACGCGCGGCTCGTGC
GGCAGTTCCCGCGCGAGCGCGTGCTTGCCGTGCGTTGCGACGTGCTCGACGAAGCCGACGTGACCGCGTTCGCGCAGGCC
GTTGCCGAGCGCTTCGGCGGCGCGGACATGCTCGTCAACAACGCGGGCCAGGGCCGCGTGTCGACGTTCGCGGACACGAC
GGACGACGCGTGGCGCGACGAACTCGAACTGAAATACTTCAGCATCATCCGCCCGACGCGCGCGTTCCTGCCGCTGCTGC
GCGCGTCGAGTGCGCCGAGCATCACCTGCGTGAATTCGCTGCTCGCGCTGCAGCCCGAGCCGCACATGGTCGCGACTTCG
TCGGCGCGCGCCGGCACGCTGAGCCTCGTCAAATCGCTCGCGACCGAGCTCGCGCCCGAGCGCGTCCGCGTCAATTCGAT
CCTGATCGGCATCGTCGAATCGGGTCAATGGCGGCGGCGCTACGACGCGCAGGCCGCGCCGGGCGAATCGTGGGAAGCGT
GGACAGCCGCGCTCGCCGCGAAGAAAAACATTCCGCTTGCGCGCTTCGGCCGGCCCGACGAGGCCGCGTGGGCGCTCTTT
TATCTCGCAACGAATCTGTCGTCTTACACGACGGGCAGCCATATCGACGTATCAGGAGGCTTTGCACGCCATGTCTAA

Upstream 100 bases:

>100_bases
GGCTCGTCGAGAAGGTCGTGCGTGCGGCGGCCGAGCTGTCGCGGCGGCTGAACTATCGGTCCGACGACGAAAACACCTAT
TTGAAGGCATTGGGATTGCG

Downstream 100 bases:

>100_bases
CCCAACCACGACCACGGTCGGCGAGCTGATTGCCGCCTTCCTCGAACAATGCGGCGTGAAGACCGCCTTCGGCGTGATCT
CGATTCACAACATGCCGATC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MIQIDLSGQVAVVTGGSSGIGYASAELFLRAGASVAICGRGDERLASAHARLVRQFPRERVLAVRCDVLDEADVTAFAQA
VAERFGGADMLVNNAGQGRVSTFADTTDDAWRDELELKYFSIIRPTRAFLPLLRASSAPSITCVNSLLALQPEPHMVATS
SARAGTLSLVKSLATELAPERVRVNSILIGIVESGQWRRRYDAQAAPGESWEAWTAALAAKKNIPLARFGRPDEAAWALF
YLATNLSSYTTGSHIDVSGGFARHV

Sequences:

>Translated_265_residues
MIQIDLSGQVAVVTGGSSGIGYASAELFLRAGASVAICGRGDERLASAHARLVRQFPRERVLAVRCDVLDEADVTAFAQA
VAERFGGADMLVNNAGQGRVSTFADTTDDAWRDELELKYFSIIRPTRAFLPLLRASSAPSITCVNSLLALQPEPHMVATS
SARAGTLSLVKSLATELAPERVRVNSILIGIVESGQWRRRYDAQAAPGESWEAWTAALAAKKNIPLARFGRPDEAAWALF
YLATNLSSYTTGSHIDVSGGFARHV
>Mature_265_residues
MIQIDLSGQVAVVTGGSSGIGYASAELFLRAGASVAICGRGDERLASAHARLVRQFPRERVLAVRCDVLDEADVTAFAQA
VAERFGGADMLVNNAGQGRVSTFADTTDDAWRDELELKYFSIIRPTRAFLPLLRASSAPSITCVNSLLALQPEPHMVATS
SARAGTLSLVKSLATELAPERVRVNSILIGIVESGQWRRRYDAQAAPGESWEAWTAALAAKKNIPLARFGRPDEAAWALF
YLATNLSSYTTGSHIDVSGGFARHV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=261, Percent_Identity=30.6513409961686, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI32483357, Length=256, Percent_Identity=27.34375, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI40254992, Length=253, Percent_Identity=28.4584980237154, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI10190704, Length=255, Percent_Identity=27.843137254902, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI5031737, Length=255, Percent_Identity=28.2352941176471, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI31542939, Length=196, Percent_Identity=30.1020408163265, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI7706318, Length=194, Percent_Identity=29.3814432989691, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI59889578, Length=234, Percent_Identity=29.4871794871795, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7705925, Length=261, Percent_Identity=26.8199233716475, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=31.0526315789474, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI126723750, Length=259, Percent_Identity=24.7104247104247, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI224922801, Length=174, Percent_Identity=29.3103448275862, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI66933014, Length=260, Percent_Identity=27.3076923076923, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=28.4153005464481, Blast_Score=71, Evalue=8e-13,
Organism=Escherichia coli, GI87082100, Length=270, Percent_Identity=30.7407407407407, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1787335, Length=258, Percent_Identity=27.5193798449612, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1789378, Length=265, Percent_Identity=29.0566037735849, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1787905, Length=259, Percent_Identity=27.7992277992278, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788459, Length=261, Percent_Identity=28.3524904214559, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI2367175, Length=256, Percent_Identity=28.125, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786812, Length=263, Percent_Identity=28.5171102661597, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=23.2558139534884, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789208, Length=260, Percent_Identity=25, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789057, Length=253, Percent_Identity=24.5059288537549, Blast_Score=64, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=32.6996197718631, Blast_Score=110, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=30.3501945525292, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=30.8270676691729, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI25147288, Length=261, Percent_Identity=29.5019157088123, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=29.6442687747036, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=29.3893129770992, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=31.9702602230483, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=30.1158301158301, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=27.5862068965517, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=27.9527559055118, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=28.125, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=29.5454545454545, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=30.0751879699248, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=28.4644194756554, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=30.0380228136882, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=30.9701492537313, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=30.7984790874525, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17555706, Length=257, Percent_Identity=27.6264591439689, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=28.030303030303, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17536025, Length=258, Percent_Identity=28.6821705426357, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=261, Percent_Identity=29.5019157088123, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=269, Percent_Identity=28.2527881040892, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=258, Percent_Identity=26.3565891472868, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=177, Percent_Identity=27.1186440677966, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=261, Percent_Identity=29.8850574712644, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=27.1375464684015, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=259, Percent_Identity=28.957528957529, Blast_Score=90, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6323882, Length=203, Percent_Identity=26.6009852216749, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=32.4324324324324, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=29.5719844357977, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=29.9610894941634, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24644337, Length=259, Percent_Identity=32.046332046332, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24644339, Length=262, Percent_Identity=29.0076335877863, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24643142, Length=261, Percent_Identity=30.6513409961686, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI28571526, Length=260, Percent_Identity=29.2307692307692, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24639444, Length=259, Percent_Identity=27.027027027027, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21355631, Length=173, Percent_Identity=28.9017341040462, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28405; Mature: 28405

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQIDLSGQVAVVTGGSSGIGYASAELFLRAGASVAICGRGDERLASAHARLVRQFPRER
CEEEECCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCHHH
VLAVRCDVLDEADVTAFAQAVAERFGGADMLVNNAGQGRVSTFADTTDDAWRDELELKYF
EEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCCCCHHHHHHHHHHHH
SIIRPTRAFLPLLRASSAPSITCVNSLLALQPEPHMVATSSARAGTLSLVKSLATELAPE
HHHCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCC
RVRVNSILIGIVESGQWRRRYDAQAAPGESWEAWTAALAAKKNIPLARFGRPDEAAWALF
CEEEEEEEEEEECCCCHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHCCCCCHHHHHHH
YLATNLSSYTTGSHIDVSGGFARHV
HHHHCCCCCCCCCEEECCCCHHCCC
>Mature Secondary Structure
MIQIDLSGQVAVVTGGSSGIGYASAELFLRAGASVAICGRGDERLASAHARLVRQFPRER
CEEEECCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCHHH
VLAVRCDVLDEADVTAFAQAVAERFGGADMLVNNAGQGRVSTFADTTDDAWRDELELKYF
EEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCCCCHHHHHHHHHHHH
SIIRPTRAFLPLLRASSAPSITCVNSLLALQPEPHMVATSSARAGTLSLVKSLATELAPE
HHHCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCC
RVRVNSILIGIVESGQWRRRYDAQAAPGESWEAWTAALAAKKNIPLARFGRPDEAAWALF
CEEEEEEEEEEECCCCHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHCCCCCHHHHHHH
YLATNLSSYTTGSHIDVSGGFARHV
HHHHCCCCCCCCCEEECCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]