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The map label for this gene is vanX [H]

Identifier: 126447129

GI number: 126447129

Start: 987665

End: 988234

Strand: Reverse

Name: vanX [H]

Synonym: BMA10247_A1051

Alternate gene names: 126447129

Gene position: 988234-987665 (Counterclockwise)

Preceding gene: 126446758

Following gene: 126447823

Centisome position: 42.0

GC content: 69.82

Gene sequence:

>570_bases
TTGAAGACATCCGCCCATCGCCTCGTCGAGATCGCGCCGCACACGCACGGCGTCGACGTCGATCTCGTCTACGCGACCGA
GCGCAATCTGACCGGCCAGCCGATCTACCGGCGCGCGCACTGCCTGCTGCTCGAGCCGGCCGAAGCGGCGCTGCGCCGCG
CGGTCGCGGTCGCCGCGCGAAGCGGCCTGCGGCTGAGAATCTATGACGCATACCGGCCGCCGCGGGCGCAGCGGATACTG
TGGGACTTCCTGCCCGATCCGAACTTCGTCGCCGATCTCGGCCGCGGCTCGAATCACAGCCGCGGCACCGCGCTCGACCT
GACGCTCGTCGACGCGAACGGCGACGCGCTCGACATGGGCACGGGCTTCGACGAGATGATCGCCGCGTCGAATCATTTCC
ACGACGGCCTGCCCGAGCCCGTGCAGCGCAACCGGCTGCTGCTGCTCGGCGTGATGCACGCGGCGGGCTTCACGCACATC
GCGAGCGAGTGGTGGCATTACGAGCTGCCCGGCTCACGCGCGCTGCCGCTGATCGACGAAGAAGCGGGCGGACCGTGGCG
GCTGATGTGA

Upstream 100 bases:

>100_bases
GACCGGCTCGGCGGCACGATCGACGCGCGCGTCGCGCGCAACCGCGAGCTGCAGCGCGAGCTCGATCAATTCGAACCCTG
AAGCCGCCGGAGCGCCGCCC

Downstream 100 bases:

>100_bases
TCGCCGACCGCGCCGACCGCGCCGCCCCCGTCGCACGCATCGCCCGCGCCGCATGCCCGGCACGCGGCGCGCCCGCCGCG
CCCGGCCCTCGGCCGGGCGC

Product: D-alanyl-D-alanine dipeptidase

Products: NA

Alternate protein names: D-Ala-D-Ala dipeptidase [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MKTSAHRLVEIAPHTHGVDVDLVYATERNLTGQPIYRRAHCLLLEPAEAALRRAVAVAARSGLRLRIYDAYRPPRAQRIL
WDFLPDPNFVADLGRGSNHSRGTALDLTLVDANGDALDMGTGFDEMIAASNHFHDGLPEPVQRNRLLLLGVMHAAGFTHI
ASEWWHYELPGSRALPLIDEEAGGPWRLM

Sequences:

>Translated_189_residues
MKTSAHRLVEIAPHTHGVDVDLVYATERNLTGQPIYRRAHCLLLEPAEAALRRAVAVAARSGLRLRIYDAYRPPRAQRIL
WDFLPDPNFVADLGRGSNHSRGTALDLTLVDANGDALDMGTGFDEMIAASNHFHDGLPEPVQRNRLLLLGVMHAAGFTHI
ASEWWHYELPGSRALPLIDEEAGGPWRLM
>Mature_189_residues
MKTSAHRLVEIAPHTHGVDVDLVYATERNLTGQPIYRRAHCLLLEPAEAALRRAVAVAARSGLRLRIYDAYRPPRAQRIL
WDFLPDPNFVADLGRGSNHSRGTALDLTLVDANGDALDMGTGFDEMIAASNHFHDGLPEPVQRNRLLLLGVMHAAGFTHI
ASEWWHYELPGSRALPLIDEEAGGPWRLM

Specific function: Hydrolyzes D-Ala-D-Ala. May have a role in cell-wall turnover [H]

COG id: COG2173

COG function: function code M; D-alanyl-D-alanine dipeptidase

Gene ontology:

Cell location: Secreted (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M15D family [H]

Homologues:

Organism=Escherichia coli, GI1787763, Length=175, Percent_Identity=49.7142857142857, Blast_Score=183, Evalue=7e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009045
- InterPro:   IPR000755 [H]

Pfam domain/function: PF01427 Peptidase_M15 [H]

EC number: =3.4.13.22 [H]

Molecular weight: Translated: 20999; Mature: 20999

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTSAHRLVEIAPHTHGVDVDLVYATERNLTGQPIYRRAHCLLLEPAEAALRRAVAVAAR
CCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCHHHCEEEEEECCHHHHHHHHHHHHHH
SGLRLRIYDAYRPPRAQRILWDFLPDPNFVADLGRGSNHSRGTALDLTLVDANGDALDMG
CCCEEEEEECCCCCHHHHHHHHCCCCCCCEECCCCCCCCCCCEEEEEEEEECCCCEEECC
TGFDEMIAASNHFHDGLPEPVQRNRLLLLGVMHAAGFTHIASEWWHYELPGSRALPLIDE
CCHHHHHHHCCCCCCCCCCCHHCCCEEEEEEHHHCCHHHHHHHCEEEECCCCCCCCEEEC
EAGGPWRLM
CCCCCEECC
>Mature Secondary Structure
MKTSAHRLVEIAPHTHGVDVDLVYATERNLTGQPIYRRAHCLLLEPAEAALRRAVAVAAR
CCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCHHHCEEEEEECCHHHHHHHHHHHHHH
SGLRLRIYDAYRPPRAQRILWDFLPDPNFVADLGRGSNHSRGTALDLTLVDANGDALDMG
CCCEEEEEECCCCCHHHHHHHHCCCCCCCEECCCCCCCCCCCEEEEEEEEECCCCEEECC
TGFDEMIAASNHFHDGLPEPVQRNRLLLLGVMHAAGFTHIASEWWHYELPGSRALPLIDE
CCHHHHHHHCCCCCCCCCCCHHCCCEEEEEEHHHCCHHHHHHHCEEEECCCCCCCCEEEC
EAGGPWRLM
CCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]