Click here to switch to the map view.

The map label for this gene is lrp [H]

Identifier: 126446556

GI number: 126446556

Start: 1352566

End: 1353024

Strand: Direct

Name: lrp [H]

Synonym: BMA10247_A1387

Alternate gene names: 126446556

Gene position: 1352566-1353024 (Clockwise)

Preceding gene: 126446633

Following gene: 126445713

Centisome position: 57.49

GC content: 66.23

Gene sequence:

>459_bases
GTGGACATCGACCGCGTCGATCGCGCGATCCTCCGCGTGCTGCAGCGCGACGCGTCGGTCTCGAACGTCGCGCTCGCCGC
GAAGGTGAACCTGAGCCCGCCCGCGTGCCTGCGCCGCGTCGAGCGGCTGAAGGAAATGGGGCTGATCCGCGGGATCGTCG
CGCTGCTCGAGCCGAAGGCGCTGAATGCGGGGATGCTCGTGATGATCGGCGTCGTGCTCGACCGCTCGACGCCCGACTCG
TTCGGCGCGTTCGAGCAGGCCGCGCAGAAGGTGTCGGGCTGCATGGAATGCCACGTCGTGACGGGCGAGTTCGACTACAT
CATGCTGATCCGCACGCGCGACAGCGATACGTTCAACCGGCTGCACGCCGAGCAGTTGCTGTACCTGCCCGGCGTGCGGC
AGATCCGCACGTTCGTCGTGCTCAAGGAGATTCTGTCGACGACGAGTTTTCCGATTTGA

Upstream 100 bases:

>100_bases
TATACTTTTCAATCAGAATTCACGTTAATTAAATTAGGAATCGTTCAGCATGCGCGCAACAAAAAAATCCTCACCGAAGG
CCGCCGCCCCACCGGCGGGC

Downstream 100 bases:

>100_bases
GCCGCGCCGCTTTCGCGCGCCGCACCGCGGACGCGAATCGCGCGCCGAACGCGCCGTCGGCGGCCCGGTGCGCGCCGCCG
ACGGCGCATGCATGCCGCCA

Product: putative leucine-responsive regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MDIDRVDRAILRVLQRDASVSNVALAAKVNLSPPACLRRVERLKEMGLIRGIVALLEPKALNAGMLVMIGVVLDRSTPDS
FGAFEQAAQKVSGCMECHVVTGEFDYIMLIRTRDSDTFNRLHAEQLLYLPGVRQIRTFVVLKEILSTTSFPI

Sequences:

>Translated_152_residues
MDIDRVDRAILRVLQRDASVSNVALAAKVNLSPPACLRRVERLKEMGLIRGIVALLEPKALNAGMLVMIGVVLDRSTPDS
FGAFEQAAQKVSGCMECHVVTGEFDYIMLIRTRDSDTFNRLHAEQLLYLPGVRQIRTFVVLKEILSTTSFPI
>Mature_152_residues
MDIDRVDRAILRVLQRDASVSNVALAAKVNLSPPACLRRVERLKEMGLIRGIVALLEPKALNAGMLVMIGVVLDRSTPDS
FGAFEQAAQKVSGCMECHVVTGEFDYIMLIRTRDSDTFNRLHAEQLLYLPGVRQIRTFVVLKEILSTTSFPI

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=151, Percent_Identity=45.0331125827815, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=27.3333333333333, Blast_Score=86, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 16914; Mature: 16914

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIDRVDRAILRVLQRDASVSNVALAAKVNLSPPACLRRVERLKEMGLIRGIVALLEPKA
CCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
LNAGMLVMIGVVLDRSTPDSFGAFEQAAQKVSGCMECHVVTGEFDYIMLIRTRDSDTFNR
CCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCEEEEEEECCCHHHHH
LHAEQLLYLPGVRQIRTFVVLKEILSTTSFPI
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDIDRVDRAILRVLQRDASVSNVALAAKVNLSPPACLRRVERLKEMGLIRGIVALLEPKA
CCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
LNAGMLVMIGVVLDRSTPDSFGAFEQAAQKVSGCMECHVVTGEFDYIMLIRTRDSDTFNR
CCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCEEEEEEECCCHHHHH
LHAEQLLYLPGVRQIRTFVVLKEILSTTSFPI
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]