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The map label for this gene is gudP [H]

Identifier: 126446408

GI number: 126446408

Start: 845947

End: 847293

Strand: Direct

Name: gudP [H]

Synonym: BMA10247_A0894

Alternate gene names: 126446408

Gene position: 845947-847293 (Clockwise)

Preceding gene: 126447361

Following gene: 126447064

Centisome position: 35.96

GC content: 69.12

Gene sequence:

>1347_bases
ATGCCCCAGCCGATCCACACCGACGCCGCGCCGCGCGCGGCCGTCGCGGCCGCCCGCGCGGCCAGCCCCGCGCGGCCGCG
CTCGAACGCGCGTTACCGGATTCTCGCGCTGCTCGCGTTCGGAACGATGATCAATTATCTCGATCGCACCGTGCTCGGCG
TCGCGGCGCCGGGGCTCACGAAAGAGCTCGGCATCGGCGCGGCGGCGATGGGCGTGATGTTCTCCGCGTTCTCGTGGACC
TACGTGCTCGCGCAGGTGCCGGGCGGCCTGCTGCTCGACCGTTTCGGCAGCAAGCTCACCTATTACTGGTCGATGACGCT
GTGGTCGCTGTTCACGCTGCTGCAGGGCTTCGTGCACGGCGTCGCGCCGCTCCTCGCGTGCCGGCTCGGGCTCGGCTTGT
CCGAGGCGCCGTGCTTTCCGACCAACAGCCGCGTCGTCGCGACGTGGTTTCCGCAGAAGGAGCGTGCGATGGCGACGGGC
ACCTATACCGTCGGCGAATACATCGGCCTCGCGTTCCTGAGCCCCGTGCTGTTCGCGCTGATGGGCGCGTTCGGCTGGCG
CTCGCTGTTCTGGGTCGTGGGCGGCGTCGGCATCGTGTTCGGCTTCGTCTGGTGGAAGTTCTATCACGAGCCGCACGACC
ATCCGCGCGCGAACGCGGCCGAGCTCGCGTACATCGAGGAAGGCGGCGGTCTCGTGCAGGCGACGGCGGGCGGCGGCTCG
CGCGCGAAGTTCAACTGGCGCGTGGCCGGCCGGCTGCTGAAGAAGCGCCAGCTCGCGGGCATCTGCCTCGGCCAGTTCGC
CGGCAACTCGACGCTCGTGTTCTTCCTCACGTGGTTCCCGACCTACCTCGCGACCGAGCGCCACATGGGCTGGCTCAAGA
TCGGCTTCTTCGCGGTGATGCCGTTCATCGCCGCGTCGGTCGGCGTGATGTTCGGCGGGCTCTTCTCCGACTGGCTGCTG
CGCCGCGGTCGATCGGCGAACGTCGCGCGCAAGCTGCCGATCATCGCGGGCCTGCTGCTCGCGTCGACGATCGTGCTCGC
GAACTACGTGCGCAGCAACGAGGCGGTGATCGCGATCATGTCGGTCGCGTTCTTCGCGCAGGGGATGGCCGCGCTCGGCT
GGACGCTCGTGTCCGACATCGCGCCCGAGGGGCTCCTCGGCGCGACGGGCGGCATCTTCAATCTCGCCGCGAATCTCGCG
GGCATCGTCACGCCGCTCGTCGTCGGCTTCATCGTCGCGGCGACCGGCTCGTTCGTCGGCGCGCTCGCGTTCATCGGCGT
GATCGCGCTGATCGGCGCGCTGTCGTACATCTTCGTCGTCGGCGACATCAAGCGGATCGAGCTGTAA

Upstream 100 bases:

>100_bases
CGCCGGATGCCGAGCGAATGTTCGAGCACTTCCGGGCGCTCGTCGCGCGCTGAATTTTCCCCCAATCCGCACATAAAGAC
AGATACATCAGGAGACATCG

Downstream 100 bases:

>100_bases
CCGCAAGCACGCGGCGCGAGCGGCGCGCGCCGCACCGGACGGAGCCGCGCGCGCTTTTTTCATCGCCGCGATGGCGGGCG
GCGAGCGGAGCGCGACCGTC

Product: anion:cation symporter (ACS) family protein

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MPQPIHTDAAPRAAVAAARAASPARPRSNARYRILALLAFGTMINYLDRTVLGVAAPGLTKELGIGAAAMGVMFSAFSWT
YVLAQVPGGLLLDRFGSKLTYYWSMTLWSLFTLLQGFVHGVAPLLACRLGLGLSEAPCFPTNSRVVATWFPQKERAMATG
TYTVGEYIGLAFLSPVLFALMGAFGWRSLFWVVGGVGIVFGFVWWKFYHEPHDHPRANAAELAYIEEGGGLVQATAGGGS
RAKFNWRVAGRLLKKRQLAGICLGQFAGNSTLVFFLTWFPTYLATERHMGWLKIGFFAVMPFIAASVGVMFGGLFSDWLL
RRGRSANVARKLPIIAGLLLASTIVLANYVRSNEAVIAIMSVAFFAQGMAALGWTLVSDIAPEGLLGATGGIFNLAANLA
GIVTPLVVGFIVAATGSFVGALAFIGVIALIGALSYIFVVGDIKRIEL

Sequences:

>Translated_448_residues
MPQPIHTDAAPRAAVAAARAASPARPRSNARYRILALLAFGTMINYLDRTVLGVAAPGLTKELGIGAAAMGVMFSAFSWT
YVLAQVPGGLLLDRFGSKLTYYWSMTLWSLFTLLQGFVHGVAPLLACRLGLGLSEAPCFPTNSRVVATWFPQKERAMATG
TYTVGEYIGLAFLSPVLFALMGAFGWRSLFWVVGGVGIVFGFVWWKFYHEPHDHPRANAAELAYIEEGGGLVQATAGGGS
RAKFNWRVAGRLLKKRQLAGICLGQFAGNSTLVFFLTWFPTYLATERHMGWLKIGFFAVMPFIAASVGVMFGGLFSDWLL
RRGRSANVARKLPIIAGLLLASTIVLANYVRSNEAVIAIMSVAFFAQGMAALGWTLVSDIAPEGLLGATGGIFNLAANLA
GIVTPLVVGFIVAATGSFVGALAFIGVIALIGALSYIFVVGDIKRIEL
>Mature_447_residues
PQPIHTDAAPRAAVAAARAASPARPRSNARYRILALLAFGTMINYLDRTVLGVAAPGLTKELGIGAAAMGVMFSAFSWTY
VLAQVPGGLLLDRFGSKLTYYWSMTLWSLFTLLQGFVHGVAPLLACRLGLGLSEAPCFPTNSRVVATWFPQKERAMATGT
YTVGEYIGLAFLSPVLFALMGAFGWRSLFWVVGGVGIVFGFVWWKFYHEPHDHPRANAAELAYIEEGGGLVQATAGGGSR
AKFNWRVAGRLLKKRQLAGICLGQFAGNSTLVFFLTWFPTYLATERHMGWLKIGFFAVMPFIAASVGVMFGGLFSDWLLR
RGRSANVARKLPIIAGLLLASTIVLANYVRSNEAVIAIMSVAFFAQGMAALGWTLVSDIAPEGLLGATGGIFNLAANLAG
IVTPLVVGFIVAATGSFVGALAFIGVIALIGALSYIFVVGDIKRIEL

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=419, Percent_Identity=25.5369928400955, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI9966811, Length=405, Percent_Identity=25.679012345679, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI9945322, Length=402, Percent_Identity=25.6218905472637, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI21322234, Length=412, Percent_Identity=25.4854368932039, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI148743791, Length=394, Percent_Identity=26.3959390862944, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI4885441, Length=360, Percent_Identity=26.1111111111111, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI148728191, Length=339, Percent_Identity=26.8436578171091, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI6912666, Length=439, Percent_Identity=23.6902050113895, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI5031955, Length=258, Percent_Identity=25.968992248062, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI223718438, Length=235, Percent_Identity=26.3829787234043, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI154800443, Length=298, Percent_Identity=25.1677852348993, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789152, Length=441, Percent_Identity=45.3514739229025, Blast_Score=398, Evalue=1e-112,
Organism=Escherichia coli, GI1789515, Length=430, Percent_Identity=45.5813953488372, Blast_Score=380, Evalue=1e-107,
Organism=Escherichia coli, GI87082320, Length=433, Percent_Identity=45.9584295612009, Blast_Score=366, Evalue=1e-102,
Organism=Escherichia coli, GI2367379, Length=442, Percent_Identity=33.710407239819, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI2367193, Length=429, Percent_Identity=28.2051282051282, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI87082071, Length=419, Percent_Identity=25.5369928400955, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115533556, Length=356, Percent_Identity=28.0898876404494, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI115533554, Length=356, Percent_Identity=28.0898876404494, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI25141316, Length=362, Percent_Identity=27.3480662983425, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25141341, Length=362, Percent_Identity=27.3480662983425, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25141318, Length=362, Percent_Identity=27.3480662983425, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17552542, Length=472, Percent_Identity=24.364406779661, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI86561091, Length=304, Percent_Identity=27.6315789473684, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17535049, Length=405, Percent_Identity=22.4691358024691, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17554148, Length=399, Percent_Identity=24.0601503759398, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71997452, Length=443, Percent_Identity=22.7990970654628, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193205400, Length=246, Percent_Identity=23.9837398373984, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32565916, Length=243, Percent_Identity=21.3991769547325, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32565914, Length=243, Percent_Identity=21.3991769547325, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17532009, Length=365, Percent_Identity=18.9041095890411, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17554962, Length=373, Percent_Identity=22.2520107238606, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550460, Length=409, Percent_Identity=26.4058679706601, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24648416, Length=444, Percent_Identity=24.7747747747748, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI21356189, Length=444, Percent_Identity=24.7747747747748, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24655255, Length=364, Percent_Identity=26.3736263736264, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19922400, Length=367, Percent_Identity=26.4305177111717, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24654215, Length=367, Percent_Identity=26.4305177111717, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573299, Length=410, Percent_Identity=24.390243902439, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI20130135, Length=415, Percent_Identity=25.3012048192771, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24655271, Length=415, Percent_Identity=25.5421686746988, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24583789, Length=389, Percent_Identity=23.9074550128535, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24641682, Length=384, Percent_Identity=26.0416666666667, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24658658, Length=419, Percent_Identity=25.5369928400955, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24653727, Length=354, Percent_Identity=25.1412429378531, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI62484226, Length=455, Percent_Identity=25.4945054945055, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24639764, Length=436, Percent_Identity=24.7706422018349, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI20129235, Length=352, Percent_Identity=26.7045454545455, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573708, Length=358, Percent_Identity=24.8603351955307, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28573707, Length=358, Percent_Identity=24.8603351955307, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24580790, Length=380, Percent_Identity=25.7894736842105, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24584153, Length=388, Percent_Identity=22.1649484536082, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45550495, Length=408, Percent_Identity=25.2450980392157, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI221474708, Length=158, Percent_Identity=34.1772151898734, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI281361682, Length=359, Percent_Identity=25.3481894150418, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24658689, Length=409, Percent_Identity=24.6943765281174, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45552797, Length=409, Percent_Identity=24.6943765281174, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20130167, Length=293, Percent_Identity=24.9146757679181, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24651789, Length=413, Percent_Identity=24.2130750605327, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24651787, Length=413, Percent_Identity=24.2130750605327, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47873; Mature: 47742

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQPIHTDAAPRAAVAAARAASPARPRSNARYRILALLAFGTMINYLDRTVLGVAAPGLT
CCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
KELGIGAAAMGVMFSAFSWTYVLAQVPGGLLLDRFGSKLTYYWSMTLWSLFTLLQGFVHG
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHH
VAPLLACRLGLGLSEAPCFPTNSRVVATWFPQKERAMATGTYTVGEYIGLAFLSPVLFAL
HHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHH
MGAFGWRSLFWVVGGVGIVFGFVWWKFYHEPHDHPRANAAELAYIEEGGGLVQATAGGGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEEECCCCEEEEECCCCC
RAKFNWRVAGRLLKKRQLAGICLGQFAGNSTLVFFLTWFPTYLATERHMGWLKIGFFAVM
CCEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHH
PFIAASVGVMFGGLFSDWLLRRGRSANVARKLPIIAGLLLASTIVLANYVRSNEAVIAIM
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
SVAFFAQGMAALGWTLVSDIAPEGLLGATGGIFNLAANLAGIVTPLVVGFIVAATGSFVG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAFIGVIALIGALSYIFVVGDIKRIEL
HHHHHHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure 
PQPIHTDAAPRAAVAAARAASPARPRSNARYRILALLAFGTMINYLDRTVLGVAAPGLT
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
KELGIGAAAMGVMFSAFSWTYVLAQVPGGLLLDRFGSKLTYYWSMTLWSLFTLLQGFVHG
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHH
VAPLLACRLGLGLSEAPCFPTNSRVVATWFPQKERAMATGTYTVGEYIGLAFLSPVLFAL
HHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHH
MGAFGWRSLFWVVGGVGIVFGFVWWKFYHEPHDHPRANAAELAYIEEGGGLVQATAGGGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEEECCCCEEEEECCCCC
RAKFNWRVAGRLLKKRQLAGICLGQFAGNSTLVFFLTWFPTYLATERHMGWLKIGFFAVM
CCEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHH
PFIAASVGVMFGGLFSDWLLRRGRSANVARKLPIIAGLLLASTIVLANYVRSNEAVIAIM
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
SVAFFAQGMAALGWTLVSDIAPEGLLGATGGIFNLAANLAGIVTPLVVGFIVAATGSFVG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAFIGVIALIGALSYIFVVGDIKRIEL
HHHHHHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9772162; 10762278 [H]