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The map label for this gene is aroE [H]

Identifier: 126447361

GI number: 126447361

Start: 845045

End: 845899

Strand: Direct

Name: aroE [H]

Synonym: BMA10247_A0893

Alternate gene names: 126447361

Gene position: 845045-845899 (Clockwise)

Preceding gene: 126447489

Following gene: 126446408

Centisome position: 35.92

GC content: 73.22

Gene sequence:

>855_bases
ATGAGCGGGCGTTCGTTTCTGATCGGCCTGATCGGCGCCGGGATCGGCGGCTCGCTGTCGCCCGCGATGCACGAGGCGGA
GGGGCGCCGGCAGGGTCTGAACTACGTGTACCGGCGCATCGATCTCGACGCGCTGGGGCTGACGGCCGACGCGCTGCCCG
AGCTGCTCGCGACCGCCGAGCGGATGGGCTTCGACGGGCTGAACATCACGCATCCGTGCAAGCAGCGCGTGATCGAGCAT
CTCGACGAATTGTCGGCGGACGCGGCCGCGCTCGGCGCGGTCAACACGGTGTGCTTCGCGCACGGCCGGCGCATCGGCCA
CAACACCGATTGGTCGGGCTTCGCGAAGGCGTTCGCGCGCGGGCTGCCGGGCGCGTCGCTCGAGCGCGTCGTGCAGCTTG
GCGCGGGCGGCGCGGGCGCGGCCGTCGCGCACGCGGCGCTCACGATGGGCGCCGCGCAACTCGCGCTCTTCGACGTCGAC
CCCGTGCGCGCGCGCTCGCTTGCCGACCAGTTGCAGGCGCGCTTTCCGCACGCGCGGCTGAGCGCCGGCGGCACGCTCGC
CGACGCGCTCGCGAACGCGACCGGCCTCATTCACGCGACGCCGACGGGCATGCTCGGGCATCCGGGCCTGCCGCTGCCGG
CGCACCTGCTGCGAAGCGGGCTCTGGGTGGCCGACATCGTCTATTTTCCGCTCGAGACCGAGCTGATCCGCGCGGCGCGC
GCGCTCGGCTGCCGCACGCTGCCGGGCGGCGGCATGGCGGTCTATCAGGCGGTCGATGCGTTCGAGCTCTTCACGGGCCG
CGCGCCGGATGCCGAGCGAATGTTCGAGCACTTCCGGGCGCTCGTCGCGCGCTGA

Upstream 100 bases:

>100_bases
TCTCGGCGCTCGCCGATGGCGTGATCTGCGGCTGCGGCACCGAGGGCTACGTGTTCGCGCTGCGGCGGCTCGCGACGCTG
ATCGGCGGGGAGGGCACGCG

Downstream 100 bases:

>100_bases
ATTTTCCCCCAATCCGCACATAAAGACAGATACATCAGGAGACATCGATGCCCCAGCCGATCCACACCGACGCCGCGCCG
CGCGCGGCCGTCGCGGCCGC

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MSGRSFLIGLIGAGIGGSLSPAMHEAEGRRQGLNYVYRRIDLDALGLTADALPELLATAERMGFDGLNITHPCKQRVIEH
LDELSADAAALGAVNTVCFAHGRRIGHNTDWSGFAKAFARGLPGASLERVVQLGAGGAGAAVAHAALTMGAAQLALFDVD
PVRARSLADQLQARFPHARLSAGGTLADALANATGLIHATPTGMLGHPGLPLPAHLLRSGLWVADIVYFPLETELIRAAR
ALGCRTLPGGGMAVYQAVDAFELFTGRAPDAERMFEHFRALVAR

Sequences:

>Translated_284_residues
MSGRSFLIGLIGAGIGGSLSPAMHEAEGRRQGLNYVYRRIDLDALGLTADALPELLATAERMGFDGLNITHPCKQRVIEH
LDELSADAAALGAVNTVCFAHGRRIGHNTDWSGFAKAFARGLPGASLERVVQLGAGGAGAAVAHAALTMGAAQLALFDVD
PVRARSLADQLQARFPHARLSAGGTLADALANATGLIHATPTGMLGHPGLPLPAHLLRSGLWVADIVYFPLETELIRAAR
ALGCRTLPGGGMAVYQAVDAFELFTGRAPDAERMFEHFRALVAR
>Mature_283_residues
SGRSFLIGLIGAGIGGSLSPAMHEAEGRRQGLNYVYRRIDLDALGLTADALPELLATAERMGFDGLNITHPCKQRVIEHL
DELSADAAALGAVNTVCFAHGRRIGHNTDWSGFAKAFARGLPGASLERVVQLGAGGAGAAVAHAALTMGAAQLALFDVDP
VRARSLADQLQARFPHARLSAGGTLADALANATGLIHATPTGMLGHPGLPLPAHLLRSGLWVADIVYFPLETELIRAARA
LGCRTLPGGGMAVYQAVDAFELFTGRAPDAERMFEHFRALVAR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=276, Percent_Identity=30.4347826086957, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1789675, Length=281, Percent_Identity=29.5373665480427, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320332, Length=270, Percent_Identity=24.4444444444444, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR013708
- InterPro:   IPR022893 [H]

Pfam domain/function: PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29784; Mature: 29652

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRSFLIGLIGAGIGGSLSPAMHEAEGRRQGLNYVYRRIDLDALGLTADALPELLATAE
CCCCCEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHH
RMGFDGLNITHPCKQRVIEHLDELSADAAALGAVNTVCFAHGRRIGHNTDWSGFAKAFAR
HHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
GLPGASLERVVQLGAGGAGAAVAHAALTMGAAQLALFDVDPVRARSLADQLQARFPHARL
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCHHH
SAGGTLADALANATGLIHATPTGMLGHPGLPLPAHLLRSGLWVADIVYFPLETELIRAAR
CCCCHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHCCCHHHHHHHHCCHHHHHHHHH
ALGCRTLPGGGMAVYQAVDAFELFTGRAPDAERMFEHFRALVAR
HHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SGRSFLIGLIGAGIGGSLSPAMHEAEGRRQGLNYVYRRIDLDALGLTADALPELLATAE
CCCCEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHH
RMGFDGLNITHPCKQRVIEHLDELSADAAALGAVNTVCFAHGRRIGHNTDWSGFAKAFAR
HHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
GLPGASLERVVQLGAGGAGAAVAHAALTMGAAQLALFDVDPVRARSLADQLQARFPHARL
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCHHH
SAGGTLADALANATGLIHATPTGMLGHPGLPLPAHLLRSGLWVADIVYFPLETELIRAAR
CCCCHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHCCCHHHHHHHHCCHHHHHHHHH
ALGCRTLPGGGMAVYQAVDAFELFTGRAPDAERMFEHFRALVAR
HHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12692562; 11572948 [H]